公开(公告)号：CA1110654A

公开(公告)日：1981-10-13

申请号：CA298909

申请日：1978-03-14

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  VAYSSIE CHARLES

IPC: C07C69/017 ,  A61K8/00 ,  A61K8/04 ,  A61K8/31 ,  A61K8/34 ,  A61K8/35 ,  A61K8/37 ,  A61K8/46 ,  A61K8/86 ,  A61K8/92 ,  A61K8/97 ,  A61K31/195 ,  A61K31/235 ,  A61Q17/00 ,  A61Q17/04 ,  B01J19/12 ,  C07C45/00 ,  C07C45/51 ,  C07C45/63 ,  C07C45/64 ,  C07C45/70 ,  C07C45/71 ,  C07C45/72 ,  C07C49/417 ,  C07C49/587 ,  C07C49/683 ,  C07C49/697 ,  C07C49/743 ,  C07C49/747 ,  C07C49/753 ,  C07C49/757 ,  C07C49/84 ,  C07C51/00 ,  C07C59/76 ,  C07C59/86 ,  C07C59/90 ,  C07C65/21 ,  C07C65/38 ,  C07C65/40 ,  C07C67/00 ,  C07C69/007 ,  C07C69/738 ,  C07C69/76 ,  C07C69/92 ,  C07C213/00 ,  C07C225/18 ,  C07C225/22 ,  C07C253/00 ,  C07C255/40 ,  C07C255/56 ,  C07C301/00 ,  C07C303/22 ,  C07C309/24 ,  C07C309/25 ,  C07C313/00 ,  C07C317/28 ,  C07C317/44 ,  C07C317/48 ,  C07C323/65 ,  C07C323/66 ,  C07C325/00 ,  C07C381/02 ,  C07D277/70 ,  C07D277/74 ,  C07D295/10 ,  C07D295/116 ,  C07C49/27 ,  C07C143/24 ,  A61K7/40

Abstract: Dérivés bromés du para-méthyl-benzylidène camphre ayant la formule: I dans laquelle Y désigne H ou le radical SO3H et ses sels avec les bases organiques ou minérales, et Z désigne les radicaux -CH2Br ou -CH BrBr. Les composés de formule I sont des composés nouveaux qui sont utiles, soit comme intermédiaires de synthèse, soit comme filtres protecteurs dans les compositions pour la protection de l'épiderme humain contre les radiations actiniques Compositions renfermant des composés de formule I. Procédé de préparation de ces composés.

公开(公告)号：FR2462159A1

公开(公告)日：1981-02-13

申请号：FR7919840

申请日：1979-08-02

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  DARMENTON PATRICK

IPC: A61K8/46 ,  A61Q3/00 ,  A61K7/04

Abstract: Brittle and damaged nails can be strengthened and revitalised by the use of at least one salt (I) of an inorganic or organic acid with benzyl-2-thiothylamine of formula C6H5-CH2-S-CH2-CH2-NH2 (II). The treated nails are stronger and have a healthier appearance.

公开(公告)号：DE3002878A1

公开(公告)日：1980-08-07

申请号：DE3002878

申请日：1980-01-28

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  MAIGNAN JEAN

IPC: A61K8/00 ,  A61K8/30 ,  A61K8/34 ,  A61K8/46 ,  A61K8/64 ,  A61K8/73 ,  A61K31/095 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q19/00 ,  C07C317/00 ,  C07C323/25 ,  A61K7/06 ,  A61K7/08 ,  A61K7/48

公开(公告)号：DE2927820A1

公开(公告)日：1980-01-24

申请号：DE2927820

申请日：1979-07-10

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  VAYSSIE CHARLES

IPC: C07C69/712 ,  A61K8/00 ,  A61K8/04 ,  A61K8/29 ,  A61K8/34 ,  A61K8/36 ,  A61K8/365 ,  A61K8/37 ,  A61K8/39 ,  A61K8/40 ,  A61K8/41 ,  A61K8/44 ,  A61K8/86 ,  A61K8/92 ,  A61K31/185 ,  A61Q17/04 ,  C07C45/00 ,  C07C45/45 ,  C07C45/67 ,  C07C45/71 ,  C07C45/74 ,  C07C49/697 ,  C07C49/743 ,  C07C49/747 ,  C07C49/753 ,  C07C49/757 ,  C07C49/84 ,  C07C51/00 ,  C07C51/353 ,  C07C59/125 ,  C07C59/86 ,  C07C59/90 ,  C07C65/38 ,  C07C65/40 ,  C07C67/00 ,  C07C67/293 ,  C07C213/00 ,  C07C217/18 ,  C07C217/32 ,  C07C217/36 ,  C07C301/00 ,  C07C303/06 ,  C07C303/08 ,  C07C303/22 ,  C07C303/32 ,  C07C309/10 ,  C07C309/23 ,  C07C309/25 ,  C07C309/42 ,  C07C309/44 ,  C07D295/00 ,  C07D295/092 ,  C09K3/00 ,  C07C143/00 ,  A61K7/40

Abstract: The invention relates to oxybenzylidene-bornanones which correspond to the general formula: in which Z and Z' denote hydrogen or a radical SO3H, at least one of the two radicals Z and Z' denoting hydrogen, R1 denotes hydrogen, an alkyl radical having 2 to 18 carbon atoms, an alkenyl radical having 3 to 18 carbon atoms, a radical +TR in which R denotes H or an alkyl radical, -(CH2)3SO3H or a divalent radical -(CH2)m or -CH2-CHOH-CH2, m having the values 1 to 10, n having the values 1 to 20 and p having the values 1 to 6, and R3 and R4 representing hydrogen or an optionally branched or hydroxylic alkyl radical, or forming an amino-aliphatic heterocyclic ring with the nitrogen atom, R2 denotes a hydrogen atom, an alkoxy radical or a divalent radical -O- bonded to the radical R1 if the latter is also divalent, and q denotes 1 or 2; if q has the value 2, R1 is a divalent radical, and, if R1 denotes hydrogen, R2 also denotes hydrogen. These compounds can be used in cosmetic compositions for providing protection against actinic rays.

公开(公告)号：NL161746B

公开(公告)日：1979-10-15

申请号：NL7013073

申请日：1970-09-03

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  BOUILLON CLAUDE

IPC: A61K8/49 ,  A61K31/44 ,  A61Q5/02 ,  A61Q15/00 ,  C07D213/89 ,  A01N9/12 ,  A61K7/00 ,  A61K31/555

公开(公告)号：CH609241A5

公开(公告)日：1979-02-28

申请号：CH1687675

申请日：1975-12-30

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  BERREBI CLAUDINE

IPC: A61K8/00 ,  A61K8/02 ,  A61K8/04 ,  A61K8/30 ,  A61K8/33 ,  A61K8/34 ,  A61K8/36 ,  A61K8/362 ,  A61K8/365 ,  A61K8/44 ,  A61K8/46 ,  A61K8/49 ,  A61K8/92 ,  A61K9/00 ,  A61K31/10 ,  A61K31/16 ,  A61K31/195 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q19/00 ,  C07C317/00 ,  C07C317/42 ,  A61K7/00

Abstract: A composition for treating oily hair or skin to reduce the oily appearance thereof comprises in an appropriate vehicle an active compound having the formula +TR wherein R3 is lower alkyl containing 1-3 carbon atoms; n= 0 or 1 with the proviso that when n= 0, and when n= 1, R2 is hydrogen; and HX represents a mineral or organic acid. The composition can be applied topically or be orally administered to a person whose hair or skin has an oily appearance to reduce said oily appearance.

公开(公告)号：IT7867555D0

公开(公告)日：1978-03-14

申请号：IT6755578

申请日：1978-03-14

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  VAYSSIE CHARLES

IPC: C07C69/017 ,  A61K8/00 ,  A61K8/04 ,  A61K8/31 ,  A61K8/34 ,  A61K8/35 ,  A61K8/37 ,  A61K8/46 ,  A61K8/86 ,  A61K8/92 ,  A61K8/97 ,  A61K31/195 ,  A61K31/235 ,  A61Q17/00 ,  A61Q17/04 ,  B01J19/12 ,  C07C45/00 ,  C07C45/51 ,  C07C45/63 ,  C07C45/64 ,  C07C45/70 ,  C07C45/71 ,  C07C45/72 ,  C07C49/417 ,  C07C49/587 ,  C07C49/683 ,  C07C49/697 ,  C07C49/743 ,  C07C49/747 ,  C07C49/753 ,  C07C49/757 ,  C07C49/84 ,  C07C51/00 ,  C07C59/76 ,  C07C59/86 ,  C07C59/90 ,  C07C65/21 ,  C07C65/38 ,  C07C65/40 ,  C07C67/00 ,  C07C69/007 ,  C07C69/738 ,  C07C69/76 ,  C07C69/92 ,  C07C213/00 ,  C07C225/18 ,  C07C225/22 ,  C07C253/00 ,  C07C255/40 ,  C07C255/56 ,  C07C301/00 ,  C07C303/22 ,  C07C309/24 ,  C07C309/25 ,  C07C313/00 ,  C07C317/28 ,  C07C317/44 ,  C07C317/48 ,  C07C323/65 ,  C07C323/66 ,  C07C325/00 ,  C07C381/02 ,  C07D277/70 ,  C07D277/74 ,  C07D295/10 ,  C07D295/116 ,  A61K

Abstract: The invention provides compounds which are particularly valuable for use as the active ingredient in sun tan lotions and creams and the like. These compounds have the general formula: in which Y denotes hydrogen or the radical SO3H or a salt thereof with an organic or inorganic base, and Z denotes the radical -CH2Br or -CHBrBr or a radical Z' which denotes the radical -CH2I, -CH2R, -CHR'R', -CHO or -COOR'', in which R denotes -NR1R2, -N+R1R2R3, -OR4, -OCOR5, -SR6, -CN, -COOR'' or -SSO3Na, in which R1 and R2 independently denote hydrogen, C1-18 alkyl or hydroxyalkyl, or R1 and R2, together with the nitrogen atom to which they are attached, denote a heterocyclic ring, R3 denotes C1-4 alkyl or hydroxyalkyl or sulphonatopropyl, R4 denotes hydrogen, alkyl, polyoxyethylene, aryl which is optionally substituted, menthyl or dialkylaminoalkyl, R5 denotes alkyl, alkenyl, aryl or a 5 or 6 membered heterocyclic ring which is optionally aromatic, and R6 denotes hydrogen, alkyl, carboxyalkyl, aminoalkyl, hydroxyalkyl, aryl or 3-alanyl, R' denotes -OR'4 or -SR'6, in which R'4 and R'6 are as defined under R4 and R6, respectively, except for hydrogen, polyoxyethylene, hydroxyalkyl, 3-alanyl and aryl, and R'' denotes hydrogen or alkyl, such that when R denotes N+R1R2R3, R1 and R2 are not hydrogen and either R3 denotes sulphonatopropyl, or the compound is in the form of a salt with an anion, which is SO4alkyl, SO3aryl, SO3alkyl or halogen or an inorganic or organic acid addition salt thereof when R denotes -NR1R2.

公开(公告)号：CH595336A5

公开(公告)日：1978-02-15

申请号：CH563977

申请日：1974-02-18

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  VAYSSIE CHARLES ,  RICHARD FRANCOISE

IPC: A61K8/00 ,  A61K20060101 ,  A61K8/34 ,  A61K8/92 ,  A61K31/235 ,  A61L9/04 ,  A61Q17/04 ,  C07C20060101 ,  C07C49/613 ,  C07C49/743 ,  C07C67/00 ,  C07C301/00 ,  C07C303/06 ,  C07C303/08 ,  C07C303/32 ,  C07C309/25 ,  C07C309/28 ,  C07C309/44 ,  C07C309/58 ,  C07F3/06 ,  C09K3/30 ,  D06P1/41 ,  D06P3/04 ,  C07C143/24

Abstract: An anti-solar cosmetic composition contains as the anti-solar agent a compound of the formula wherein R represents a member selected from the group consisting of hydrogen, a halogen selected from the group consisting of chlorine and fluorine and alkyl containing 1-4 carbon atoms; R' and R'' each independently represent a member selected from the group consisting of hydrogen and SO3M wherein M represents a member selected from the group consisting of hydrogen, organic ammonium group and a metal, wherein at least one of R' and R'' is other than hydrogen, and R'' is a substituent at the para or meta position relative to the bornylidene ring. The anti-solar agent is present in amounts of 0.5-10 percent by weight of said composition.

公开(公告)号：CA1015371A

公开(公告)日：1977-08-09

申请号：CA181767

申请日：1973-09-24

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  BOUILLON CLAUDE ,  VAYSSIE CHARLES

IPC: A61K8/00 ,  A61K20060101 ,  A61K8/34 ,  A61K8/40 ,  A61K8/46 ,  A61K33/40 ,  A61L20060101 ,  A61Q5/10 ,  A61Q17/00 ,  A61Q17/04 ,  C07C20060101 ,  C07C225/16 ,  C07C225/22 ,  C08K5/03 ,  C09K3/00 ,  D06P1/41 ,  D06P3/04

公开(公告)号：FR2282426A2

公开(公告)日：1976-03-19

申请号：FR7428478

申请日：1974-08-19

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  VAYSSIE CHARLES ,  RICHARD FRANCOISE

IPC: C07C143/24 ,  A61K7/44

Abstract: Ultra-violet absorbing agents have the formula:- where R' is H or SO3M and R'' is SO3M; M is H, a metal or an organic ammonium group. Cosmetic compositions contain the above cpds. for protection against light. The cpds. may also be used to protect human skin against U.V. rays. They protect against light of 280-315 nm but allow light of 315-320 nm to pass. Also the cpds. have improved solubility, particularly in water, compared with 3-benzylidene camphor or 4-methyl-3-benzylidene camphor. Prepn. is by reacting the corresponding cpd. where R" is H with conc. sulphuric acid, oleum or chlorsulphonic acid, followed by salt formation with a cpd. bearing the radical M.