公开(公告)号：JP2010101819A

公开(公告)日：2010-05-06

申请号：JP2008275113

申请日：2008-10-27

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： USHIO KOJI ,  NAKATANI MASAYA ,  TAKAHASHI MAKOTO ,  YAMAMOTO KENJU ,  UEDA SATOSHI

IPC: G01N27/28 ,  G01N27/00 ,  G01N27/416

Abstract: PROBLEM TO BE SOLVED: To improve measurement accuracy by preventing surfaces of sheets of sensor chips from being covered with air bubbles. SOLUTION: A cell electrophysiological sensor is provided with a mounted plate 8 having through-holes 7 and the sensor chips 9 inserted in the through-holes 7. The sensor chips 9 have the sheets 10 having conduction holes 12. A plurality of protrusions 13 in contact with ends of the sensor chips 9 are formed at internal walls of the through-holes 7. The protrusions 13 are arranged in such a way that gaps may be present between each tip and tips of adjacent protrusions 13. This invention can thereby enlarge cross-sectional areas of the through-holes 7 by amounts of the gaps. As a result of this, the surfaces of the sheets 10 is prevented from being covered with air bubbles and measurement accuracy is improved. COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：通过防止传感器芯片的表面被气泡覆盖来提高测量精度。 解决方案：细胞电生理传感器设置有安装板8，安装板8具有通孔7，传感器芯片9插入通孔7.传感器芯片9具有带有导电孔12的片10。 在通孔7的内壁上形成有与传感器芯片9的端部相接触的突出部13.突起部13的布置方式使得相邻的突起部13的各端部和前端之间可以存在间隙。本发明可以 从而通过间隙的量来扩大通孔7的横截面面积。 结果，防止了片材10的表面被气泡覆盖，并提高了测量精度。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2009145097A

公开(公告)日：2009-07-02

申请号：JP2007320535

申请日：2007-12-12

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： NAKATANI MASAYA ,  DANIEL YAZBECK

IPC: G01N33/53 ,  G01N21/78

Abstract: PROBLEM TO BE SOLVED: To provide a chemical material identifying sensor for surely arranging, at a predetermined portion, a bead which has caused hybridization with a target material such as many chemical materials, with no need of a chemical bonding portion, and to provide a measuring method using it. SOLUTION: This sensor includes a plate 1 where a recess 2 having a through-hole 3 is arranged and a first and a second region 4, 5 which are divided by the plate 1. While a micro particle 11 having a probe function is disposed at the recess 2 of the through-hole, a liquid is filled in one of the first, the second region 4, 5 and in the through-hole 3. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种化学物质识别传感器，用于在预定部分确保在不需要化学键合部分的情况下与诸如许多化学材料的目标材料杂交的珠粒，以及 以提供使用它的测量方法。 解决方案：该传感器包括板1，其中布置有具有通孔3的凹部2和由板1分隔的第一和第二区域4,5。而具有探针功能的微粒11 设置在通孔的凹部2处，在第一，第二区域4,5和通孔3中的一个中填充液体。（C）2009，JPO＆INPIT

公开(公告)号：JP2009124968A

公开(公告)日：2009-06-11

申请号：JP2007301497

申请日：2007-11-21

Applicant: PANASONIC CORP

Inventor： USHIO KOJI ,  NAKATANI MASAYA ,  HIRAOKA SOICHIRO ,  OSHIMA AKIYOSHI

IPC: C12M1/34 ,  G01N27/06 ,  G01N27/416 ,  G01N35/10

Abstract: PROBLEM TO BE SOLVED: To provide an apparatus for measuring electrophysiological phenomenon of cells that can realize high-accuracy measurements in stable manner. SOLUTION: The apparatus for measuring electrophysiological phenomenon of cells is constituted of a cellular electrophysiology sensor, produced by fixing a sensor chip 2 which is constituted of a thin plate 3, having a through-hole 5 and a frame 4 for holding the plate to the inner side of the opening of a substrate 1 which has an opening; and a dispensing means for filling a measuring liquid 12 into a cavity 6 of the sensor chip 2. The dispensing means has a head part 8 of a non-contact jet dispenser to make liquid droplets 12a fly into the cavity 6, and a moving mechanism. COPYRIGHT: (C)2009,JPO&INPIT

公开(公告)号：JP2009103705A

公开(公告)日：2009-05-14

申请号：JP2008310641

申请日：2008-12-05

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： NAKATANI MASAYA ,  YOSHIDA TAKUJI ,  KOJIMA MASATOSHI

IPC: G01N27/28 ,  C12M1/34 ,  G01N27/00 ,  G01N27/416

CPC classification number: G01N33/48728

Abstract: PROBLEM TO BE SOLVED: To provide a cell electric physiology measurement device in which less breakage such as the cracking of a thin sheet occurs and which has excellent productivity. SOLUTION: This cell electric physiology measurement device 1 includes the thin sheet 7 and a frame 6. The thin sheet includes a first surface 3a and a second surface 4a, recessed parts 8 opened to the first surface 3a side, and through-holes 9 opened to the second surface 4a side. The frame 6 is brought into contact with the thin sheet outer peripheral part 4b of the thin sheet 7 on the second surface 4a side. The recessed parts 8 have an inner wall whose vertical cross section is constituted by a curve bent outside the recessed parts 8. The upper outer periphery end 3b of the thin sheet 7 has a round shape whose vertical cross section is constituted by a curve bent inside the thin sheet 7 from the first surface 3a side to the second surface 4a side. Thus, this invention can easily achieve a structure where the outer peripheral part 4b of the thin sheet 7 does not protrude from the outer peripheral part 6a of the frame 6. The cell electric physiology measurement device 1 less causing breakage such as the cracking of the thin sheet 7 and having excellent productivity can be provided by this structure. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种细胞电生理学测量装置，其中发生较少的破裂，例如薄片的破裂，并且具有优异的生产率。 解决方案：该电池电生理测量装置1包括薄片7和框架6.薄片包括第一表面3a和第二表面4a，通向第一表面3a侧的凹部8， 孔9向第二表面4a侧开口。 框架6与第二表面4a侧的薄片7的薄片外周部4b接触。 凹部8具有内壁，其垂直截面由弯曲在凹部8的外侧的曲线构成。薄片7的上外周端3b具有圆形，其垂直截面由弯曲内侧的曲线构成 薄板7从第一表面3a侧到第二表面4a侧。 因此，本发明可以容易地实现薄片7的外周部分4b不从框架6的外周部分6a突出的结构。电池电生理学测量装置1不会导致破裂 可以通过该结构提供薄片7并具有优异的生产率。 版权所有（C）2009，JPO＆INPIT