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61.发明专利
公开(公告)号：CA3080116A1
公开(公告)日：2019-05-02
申请号：CA3080116
申请日：2018-10-24
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： STARCK JEROME-BENOIT , DURAND DIDIER , CHEN I-JEN , LE TIRAN ARNAUD , ORTUNO JEAN-CLAUDE , NYERGES MIKLOS , LIGETI MELINDA , FEJES IMRE
IPC: C07D498/22 , A61K31/407 , A61P35/00
Abstract: Composé de formule (I): dans laquelle A1, A2, Ra, Rb, Rc, Rd, R3, R4, X, Y et G sont tels que définis dans la description, et leur utilisation dans la fabrication de médicaments.
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62.发明专利
公开(公告)号：EA027444B1
公开(公告)日：2017-07-31
申请号：EA201400754
申请日：2014-07-22
Applicant: SERVIER LAB , VERNALIS (R&D) LTD
Inventor： LE TIRAN ARNAUD , LE DIGUARHER THIERRY , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , GUILLOUZIC ANNE-FRANCOISE , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN
IPC: C07F9/62 , A61K31/661 , A61P35/00
Abstract: Соединенияформулы (I)вкоторой X, Y, А, А, R, R, R, R, R, R, T и Rпринимаютзначения, определенныев описании. Лекарственныесредства.
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63.发明专利
公开(公告)号：GEP201706686B
公开(公告)日：2017-06-26
申请号：GEAP2014013527
申请日：2014-07-21
Applicant: SERVIER LAB , VERNALIS (R & D) LTD
Inventor： LE TIRAN ARNAUD , LE DIGUARHER THIERRY , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , GUILLOUZIC ANNE-FRANÇOISE , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , FEJES IMR , TATAI JANOS , NYERGES MIKLOS LAZLO , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN , DURAND DIDIER
IPC: C07D401/14 , A61K31/4709 , A61P35/00 , A61P37/00 , C07D401/10 , C07D405/14 , C07D471/04 , C07D491/10 , C07D498/04
Abstract: Compound of formula (I), method for preparation thereof, pharmaceutical compositions on basis thereof and usage therefor drug preparation for the treatment of cancer, and immune system and autoimmune diseases.
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公开(公告)号：CA2919572C
公开(公告)日：2017-06-20
申请号：CA2919572
申请日：2014-07-22
Applicant: VERNALIS (R&D) LTD , SERVIER LAB
Inventor： DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN , WALMSLEY CLAIRE , DODSWORTH MARK , MEISSNER JOHANNES W G , BROUGH PAUL , FEJES IMRE , TATAI JANOS , NYERGES MIKLOS , KOTSCHY ANDRAS , SZLAVIK ZOLTAN , GENESTE OLIVIER , LE TIRAN ARNAUD , LE DIGUARHER THIERRY , HENLIN JEAN-MICHEL , STARCK JEROME-BENOIT , GUILLOUZIC ANNE-FRANCOISE , DE NANTEUIL GUILLAUME
IPC: C07D401/14 , A61K31/4709 , A61K31/4725 , A61P35/00 , A61P37/00 , C07D401/10 , C07D405/14 , C07D409/14 , C07D471/04
Abstract: Compounds of formula (I): (I) wherein Het, R3, R4, R5, R7, R8, R9, T, p, p', q, and q' are as defined in the description are pro-apoptotic agents useful in the treatment of cancers and of auto-immune and immune system diseases.
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65.发明专利
公开(公告)号：EA026906B1
公开(公告)日：2017-05-31
申请号：EA201400753
申请日：2014-07-22
Applicant: SERVIER LAB , VERNALIS (R&D) LTD
Inventor： LE TIRAN ARNAUD , LE DIGUARHER THIERRY , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , GUILLOUZIC ANNE-FRANCOISE , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , FEJES IMRE , TATAI JANOS , NYERGES MIKLOS , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN , DURAND DIDIER
IPC: C07D401/14 , A61K31/4025 , A61K31/407 , A61K31/4427 , A61K31/4709 , A61K31/5377 , A61P35/00 , C07D405/14 , C07D413/14 , C07D471/04
Abstract: Настоящееизобретениеотноситсяк соединениямформулы (I), вкоторой A, A, R, R, R, R, R, R, RиТ принимаютуказанныезначения, атакжек способуихполученияи кфармацевтическимкомпозициям, содержащихих, которыепредназначеныдляпримененияв качествепроапоптотическихагентов.
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Patent Agency Ranking
公开(公告)号：AU2014294867A1
公开(公告)日：2016-02-11
申请号：AU2014294867
申请日：2014-07-22
Applicant: VERNALIS R&D LTD , SERVIER LAB
Inventor： LE TIRAN ARNAUD , LE DIGUARHER THIERRY , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN
IPC: C07D471/04 , A61K31/4709 , A61K31/4985 , A61P35/00 , A61P37/00 , C07D487/04 , C07D519/00
Abstract: The invention relates to compounds of formula (I), wherein R
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公开(公告)号：CL2014001865A1
公开(公告)日：2015-06-26
申请号：CL2014001865
申请日：2014-07-15
Applicant: SERVIER LAB , VERNALIS R&D LTD
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公开(公告)号：MD20140073A2
公开(公告)日：2015-01-31
申请号：MD20140073
申请日：2014-07-15
Applicant: SERVIER LAB , VERNALIS R & D LTD
Inventor： LE TIRAN ARNAUD , LE DIGUARHER THIERRY , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , GUILLOUZIC ANNE-FRANCOISE , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN
IPC: C07D401/10 , A61K31/4725 , A61P35/00 , A61P37/00
Abstract: Invenţia se referă la compuşii cu formula (I):unde X, Y, A1, A2, Ra, Rb, Rc, Rd, R3, R4, T şi R5 sunt definiţi în descrierea invenţiei.Invenţia se referă, de asemenea, la un procedeu de obţinere a compuşilor cu formula (I), la compoziţii farmaceutice, care conţin un compus cu formula (I) sau o sare de adiţie a acestuia cu un acid sau o bază acceptabilă farmaceutic, şi la utilizarea compoziţiilor farmaceutice în fabricarea medicamentelor.
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公开(公告)号：FR3008979A1
公开(公告)日：2015-01-30
申请号：FR1357259
申请日：2013-07-23
Applicant: SERVIER LAB , VERNALIS R & D LTD
Inventor： LE TIRAN ARNAUD , LE DIGUARHER THIERRY , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , GUILLOUZIC ANNE-FRANCOISE , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN
IPC: C07F9/09 , A61K31/6615 , A61P35/00 , A61P37/00
Abstract: Composés de formule (I) : dans laquelle X, Y, A1, A2, Ra, Rb, Rc, Rd, R3, R4, T et R5, sont tels que définis dans la description.
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公开(公告)号：CL2014001829A1
公开(公告)日：2015-01-02
申请号：CL2014001829
申请日：2014-07-10
Applicant: SERVIER LAB , VERNALIS R & D LTD
Inventor： LE DIGUARHER THIERRY , CASARA PATRICK , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , GRAHAM CHRISTOPHER JOHN , CHEN I-JEN , GENESTE OLIVIER , HICKMAN JOHN , DEPIL STEPHANE , LE TIRAN ARNAUD , NYERGES MIKLOS , DE NANTEUIL GUILLAUME
IPC: C07D471/00 , A61K31/435 , A61P35/00 , C07D471/04 , C07D487/04 , C07D491/052
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