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公开(公告)号:JP2002143298A
公开(公告)日:2002-05-21
申请号:JP2000349170
申请日:2000-11-16
Applicant: TORAY INDUSTRIES
Inventor: SUGAYA HIROYUKI
Abstract: PROBLEM TO BE SOLVED: To provide a blood treatment apparatus which is excellent in permeation performance and is miniaturized. SOLUTION: In this apparatus, the effective length of a hollow fiber membrane bundle is 20 cm or more and less than 40 cm, the inside diameter of the hollow fiber membrane is 150 μm or more and less than 45 μm, a filling ratio of the fiber bundle is 55% or more and less than 70%, a bovine blood filtration coefficient is 50 ml/m2 hr mmHg or more, and a pure water filtration coefficient is 200 ml/m2 hr mmHg or more.
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公开(公告)号:JP2002102341A
公开(公告)日:2002-04-09
申请号:JP2000298994
申请日:2000-09-29
Applicant: TORAY INDUSTRIES
Inventor: UENO YOSHIYUKI , AGA YOSHIHIRO , SUGAYA HIROYUKI
Abstract: PROBLEM TO BE SOLVED: To provide an adsorptive material capable of selectively adsorbing LDL oxide with substantially no loss of the effective components in body fluid. SOLUTION: The adsorptive material prepared by imparting a dialkylaminoalkyldextran to a supporting body selectively adsorbs the LDL oxide and therefore the material is capable of removing the LDL oxide with substantially no loss of the effective components in the body fluid.
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公开(公告)号:JP2001238946A
公开(公告)日:2001-09-04
申请号:JP2000390238
申请日:2000-12-22
Applicant: TORAY INDUSTRIES
Inventor: AGA YOSHIHIRO , YAMADA TOMOKO , SUGAYA HIROYUKI
Abstract: PROBLEM TO BE SOLVED: To provide a membrane type lipoperoxide adsorber which is capable of adsorbing and removing the lipoperoxide in blood. SOLUTION: The membrane type lipoperoxide adsorber is 10 to 30 nm in the radius of rotation of polyvinyl pyrrolidone corresponding to a molecular weight 1,000,000 in a filler liquid.
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公开(公告)号:JP2000126287A
公开(公告)日:2000-05-09
申请号:JP29943898
申请日:1998-10-21
Applicant: TORAY INDUSTRIES
Inventor: KAWASHIMA MADOKA , SUGAYA HIROYUKI
IPC: A61M1/18
Abstract: PROBLEM TO BE SOLVED: To improve a blood remaining characteristic by passing a model blood which exhibits the behavior similar to the behavior of the human total blood of a specific temperature in a relation between a viscosity and a shear rate in a specific amount in such a manner that the residual amount of the model blood at the time of washing with a specified amount of a phosphoric acid buffer solution of a specific pH and specific formulation attains a specific value or below. SOLUTION: The model blood which exhibits the behavior similar to the behavior of the human total blood of 37 deg.C in the relation between the viscosity and the shear rate is introduced into the hollow fiber type blood purifying device at a flow rate of 1.28 times the volume of the flow passage of this device. The hollow fiber membranes are then washed by passing the phosphoric acid buffer solution of pH 7.5 at 125 ml/m2 per unit inside surface area of the hollow fiber membranes and at a flow rate of 100 ml/min. The human total blood is hematocrit(ht) 40%.total protein(TP) 8. The phosphoric acid buffer solution is 5.33 mmol disodium hydrogenphoshate dodecahydrate, 1.34 mmol potassium dihydrogenphoshate and 154 mmol sodium chloride. The remaining of the blood after washing is confined to
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公开(公告)号:JP2010223576A
公开(公告)日:2010-10-07
申请号:JP2010039755
申请日:2010-02-25
Applicant: TORAY INDUSTRIES
Inventor: UENO YOSHIYUKI , OSABE MASAHIRO , SUGAYA HIROYUKI
Abstract: PROBLEM TO BE SOLVED: To provide a compact light-weighted hollow fiber membrane type heat exchanger, capable of preventing a refrigerant from being leaked out of the heat exchanger. SOLUTION: This hollow fiber membrane type heat exchanger is built in with a hollow fiber membrane containing a polymer with a hydrophilic group as a constitutive component, and having 15 mL/hr/mmHg/m 2 or less of water permeability. COPYRIGHT: (C)2011,JPO&INPIT
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公开(公告)号:JP2003260340A
公开(公告)日:2003-09-16
申请号:JP2002068050
申请日:2002-03-13
Applicant: TORAY INDUSTRIES
Inventor: ITO AKIHIKO , SUGAYA HIROYUKI
Abstract: PROBLEM TO BE SOLVED: To provide a polysulfone membrane with suppressed adsorption of proteins as a membrane for separation or concentration of antigens, enzymes or the like or for hemocatharsis by dialysis of blood or filtration of blood. SOLUTION: The membrane comprises a polysulfone resin containing a hydrophilic polymer or a polymer having a hydrophilic segment. In the IR absorption spectra of the membrane measured at 100 points with a 20×20 μm angle of view, the number of measuring points satisfying an inequality of (Aco)/(Acc)≤0.15 is ≤5, wherein Aco is the intensity of the absorption peak indicating C=O near 1660 cm -1 and Acc is the intensity of the absorption peak indicating the benzene ring C=C in the polysulfone near 1580 cm -1 . The average μof the ratio (Aco)/(Acc) is ≥0.1 and COPYRIGHT: (C)2003,JPO
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公开(公告)号:JP2002102692A
公开(公告)日:2002-04-09
申请号:JP2000298995
申请日:2000-09-29
Applicant: TORAY INDUSTRIES
Inventor: AGA YOSHIHIRO , UENO YOSHIYUKI , SUGAYA HIROYUKI
Abstract: PROBLEM TO BE SOLVED: To provide a manufacturing method for lipoperoxide-adsorbing material capable of adsorbing and removing a peroxide lipid. SOLUTION: In the manufacturing method for lipoperoxide-adsorbing material, a cationic polymer is immobilized on a support by irradiating a radiation to the support in the state that the cationic polymer is deposited thereon.
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公开(公告)号:JP2002102339A
公开(公告)日:2002-04-09
申请号:JP2000298992
申请日:2000-09-29
Applicant: TORAY INDUSTRIES
Inventor: AGA YOSHIHIRO , UENO YOSHIYUKI , SUGAYA HIROYUKI
IPC: A61M1/36 , B01J20/26 , B01J20/28 , C08L39/06 , C08L79/02 , C08L81/06 , C08L101/00 , C08L101/02
Abstract: PROBLEM TO BE SOLVED: To provide a lipoperoxide adsorptive material capable of adsorbing away lipoperoxide. SOLUTION: This lipoperoxide adsorptive material is prepared by imparting a cationic polymer to a supporting body of >=0.1 m2/g in specific surface area.
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公开(公告)号:JP2002028461A
公开(公告)日:2002-01-29
申请号:JP2000213872
申请日:2000-07-14
Applicant: TORAY INDUSTRIES
Inventor: AGA YOSHIHIRO , UENO YOSHIYUKI , SUGAYA HIROYUKI
Abstract: PROBLEM TO BE SOLVED: To provide a hollow yarn membrane for adsorbing peroxylipid which can selectively adsorb and remove the peroxylipid. SOLUTION: The hollow yarn membrane for adsorbing peroxylipid is distinguished by that a cationic polymer is contained in a hollow yarn membrane raw material.
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公开(公告)号:JP2002001073A
公开(公告)日:2002-01-08
申请号:JP2000181036
申请日:2000-06-16
Applicant: TORAY INDUSTRIES
Inventor: SAKAI YOSHITADA , KURACHI TOMOKO , SUGAYA HIROYUKI
Abstract: PROBLEM TO BE SOLVED: To prepare a membrane capable of removing a cationic substance safely and selectively. SOLUTION: The membrane capable of selectively removing cationic peptide or/and cationic low molecular weight protein and a cationic substance is obtained by using such material as a membrane material that 0.1-3% substance having anionic properties is introduced by a chemical bond.
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