公开(公告)号：WO1991003233A1

公开(公告)日：1991-03-21

申请号：PCT/US1989003801

申请日：1989-09-05

Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION

Inventor： UNIVERSITY OF UTAH RESEARCH FOUNDATION ,  STANLEY, Theodore, H. ,  HAGUE, Brian

IPC: A61K09/20

CPC classification number: A61K9/0056

Abstract: The present invention is directed to methods and compositions for noninvasively administering lipophilic drugs in a dose-to-effect manner to produce antimigraine, oxytoxic, antiemetic, hypoglycemic, anti-Parkinsonian, antidiuretic, antifungal, antisecretory, or bronchodilator activity. A patient is put at ease when given the lollipop, and the lipophilic drug rapidly enters the patient's bloodstream as the lollipop is sucked. When treating the patient, the physician can observe the patient's condition and terminate the use of the lollipop when it has had a desired effect on the patient. The drug-containing lollipop can be self-administered by the patient in response to subjective symptoms and to the patient's susceptibility to the lipophilic drug.

Abstract translation: 本发明涉及以剂量效应方式非侵入性地施用亲脂性药物以产生抗偏头痛，含氧毒性，止吐药，降血糖，抗帕金森病，抗利尿，抗真菌，抗分泌或支气管扩张剂活性的方法和组合物。 当给予棒棒糖时，患者放心，并且当吸食棒棒糖时，亲脂性药物迅速进入病人的血液流中。 当治疗患者时，医生可以观察患者的状况，并且当对患者具有期望的效果时终止棒棒糖的使用。 药物的棒棒糖可以由患者自主施用以响应主观症状和患者对亲脂性药物的易感性。