公开(公告)号：US20160374596A1

公开(公告)日：2016-12-29

申请号：US15191708

申请日：2016-06-24

Applicant: Fresenius Medical Care Holdings, Inc.

Inventor： Louis L. Barrett

IPC: A61B5/1455 ,  G01N21/27 ,  A61B5/00 ,  G01N33/49

CPC classification number: A61B5/1455 ,  A61B5/0022 ,  A61B5/14557 ,  A61B2560/0223 ,  G01J1/0214 ,  G01J3/0205 ,  G01J3/28 ,  G01J3/42 ,  G01J2001/444 ,  G01N15/06 ,  G01N21/274 ,  G01N21/314 ,  G01N21/3577 ,  G01N33/49 ,  G01N2015/0065 ,  G01N2015/0693 ,  G01N2201/062 ,  G01N2201/0624

Abstract: A measurement system for measuring blood characteristics includes a controller, an emitter, a sensor, a reference photo sensor, and a mask. The emitter emits light at a plurality of wavelengths from a first side of a blood flow channel to a second side of the blood flow channel. The sensor is provided on the second side of the blood flow channel. The reference photo sensor is provided on the first side of the blood flow channel. The mask is provided on the first side blocking reflected light other than from the light from the emitter to enter the reference photo sensor. The controller compensates measurements from the sensor based upon measurements from the reference photo sensor.

Abstract translation: 用于测量血液特性的测量系统包括控制器，发射器，传感器，参考光传感器和掩模。 发射器从血流通道的第一侧到血流通道的第二侧以多个波长发射光。 传感器设置在血流通道的第二侧。 参考光传感器设置在血流通道的第一侧。 掩模设置在第一面上，阻挡来​​自发射器的光之外的反射光，以进入参考光传感器。 控制器根据参考光电传感器的测量值补偿传感器的测量结果。

公开(公告)号：US09389171B2

公开(公告)日：2016-07-12

申请号：US13655305

申请日：2012-10-18

Applicant: Bluepoint-Medical GmbH & Co. KG

Inventor： Martin Degner ,  Nils Damaschke ,  Hartmut Ewald

IPC: G01N21/59 ,  G01N21/27 ,  G01J3/42 ,  G01N21/31 ,  G01N21/33 ,  G01N21/3577 ,  G01J3/10

CPC classification number: G01N21/274 ,  G01J3/10 ,  G01J3/42 ,  G01N21/314 ,  G01N21/33 ,  G01N21/3577 ,  G01N2201/062 ,  G01N2201/0624

Abstract: The present invention relates to a device for determining the concentration of substances in fluid media.

Abstract translation: 本发明涉及一种用于确定流体介质中物质浓度的装置。

公开(公告)号：US20150346085A1

公开(公告)日：2015-12-03

申请号：US14648855

申请日：2013-12-04

Applicant: SP3H

Inventor： Sylvain OBERTI ,  Johan FOURNEL

IPC: G01N21/27 ,  G01N21/3504

CPC classification number: G01N21/3577 ,  G01N21/274 ,  G01N21/3504 ,  G01N2021/3181 ,  G01N2201/062 ,  G01N2201/0624 ,  G01N2201/121 ,  G01N2201/1211 ,  G01N2201/124 ,  G01N2201/1242 ,  G01N2201/1247 ,  G01N2201/127 ,  G01N2201/12723

Abstract: A method for controlling a spectrometer for analyzing a product includes steps of: acquiring a measurement representative of the operation of a light source, determining, depending on the measurement, a value of supply current of the light source, and/or a value of integration time of light-sensitive cells of a sensor, disposed on a route of a light beam emitted by the light source and having interacted with a product to be analyzed, and if the integration time and/or supply current value is between threshold values, supplying the light source with a supply current corresponding to the determined supply current value, adjusting the integration time of a light-sensitive cell to the determined integration time value, and acquiring light intensity measurements supplied by the sensor, enabling a spectrum to be formed.

Abstract translation: 一种用于控制用于分析产品的光谱仪的方法包括以下步骤：获取代表光源的操作的测量，根据测量确定光源的电源电流的值和/或积分值 传感器的感光单元的时间设置在由光源发射的光束的路径上并且与待分析的产品相互作用，并且如果积分时间和/或电源电流值在阈值之间，则提供 所述光源具有与所确定的电源电流值相对应的电源电流，将感光单元的积分时间调整到所确定的积分时间值，以及获取由所述传感器提供的光强度测量值，从而能够形成光谱。

公开(公告)号：US09121727B2

公开(公告)日：2015-09-01

申请号：US13478297

申请日：2012-05-23

Applicant: Laurent Chiesi ,  Hynek Raisigel ,  Gilles Chabanis

Inventor： Laurent Chiesi ,  Hynek Raisigel ,  Gilles Chabanis

IPC: H01J40/14 ,  G01D3/036 ,  G01D5/34

CPC classification number: G01D3/036 ,  G01D5/34 ,  G01N2201/0624

Abstract: A detection system that includes an emitter, a power supply source, a receiver, a detector, and a processor. The emitter includes a light-emitting diode that emits a luminous signal. The power supply source applies a constant voltage to the light-emitting diode. The receiver senses the luminous signal emitted by the light-emitting diode and generates a first input signal representative of the luminous signal detected. The detector measures the current passing through the light-emitting diode and generates a second input signal representative of the current measured. The processor is connected to the receiver and provides an output signal as a function of the first input signal and of the second input signal.

Abstract translation: 一种检测系统，包括发射器，电源，接收器，检测器和处理器。 发射器包括发射发光信号的发光二极管。 电源对发光二极管施加恒定电压。 接收器感测由发光二极管发出的发光信号，并产生表示检测到的发光信号的第一输入信号。 检测器测量通过发光二极管的电流，并产生代表所测量电流的第二输入信号。 处理器连接到接收器，并提供作为第一输入信号和第二输入信号的函数的输出信号。

公开(公告)号：US20140154792A1

公开(公告)日：2014-06-05

申请号：US14234136

申请日：2012-07-20

Applicant: BIOSENSIA PATENTS LIMITED

Inventor： Shane Moynihan ,  Diarmuid Flavin

IPC: G01N21/64 ,  G01N33/53

CPC classification number: G01N21/6486 ,  G01N21/278 ,  G01N21/645 ,  G01N21/6452 ,  G01N33/5302 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6441 ,  G01N2021/6471 ,  G01N2201/0624 ,  G01N2201/0627 ,  G01N2201/0648 ,  G01N2201/0693

Abstract: The present disclosure, among other things, describes a reader system for analyzing one or more analytes in a fluid sample, comprising a casing (204) with at least one port (201) leading to a holster (301) which is configured to receive a cartridge (107) comprising a vertically oriented immunoassay device for analyzing one or more analytes in a fluid sample, an optical system (121) with excitation optics comprising a light source (302) and an excitation lens (305) configured to transmit light from the light source (302) and thereby excite a region of the vertically oriented immunoassay device when a cartridge (107) is placed in the holster (301), and collection optics comprising a photosensor (306) and a collection lens (307) configured to collect emitted light from the vertically oriented immunoassay device when a cartridge (107) is placed in the holster (301), an electromechanical motor system (106) configured to move the holster (301) in a vertical direction with respect to the optical system (121) so that the optical system (121) can interrogate different regions of the vertically oriented immunoassay device when a cartridge (107) is placed in the holster (301), and one or more digital processors (104a, 104b) and associated electronics configured to receive data from and control the optical system (121) and to control the electromechanical motor system (106).

Abstract translation: 本公开尤其描述了用于分析流体样品中的一种或多种分析物的读取器系统，其包括具有至少一个通向皮套（301）的端口（201）的壳体（204），所述壳体被配置为接收 盒（107）包括用于分析流体样品中的一种或多种分析物的垂直取向的免疫测定装置，具有激发光学元件的光学系统（121），其包括光源（302）和激发透镜（305），所述光学系统被配置为透射来自 并且由此当盒（107）被放置在机架（301）中时激发垂直取向的免疫测定装置的区域，并且收集光学器件包括光电传感器（306）和收集透镜（307），其被配置为收集 当盒（107）被放置在机架（301）中时，来自垂直取向的免疫测定装置的光发射;机构电动机系统（106），被配置成相对于所述光学装置在垂直方向上移动所述机架 cal系统（121），使得当盒（107）被放置在机架（301）中时，光学系统（121）可以询问垂直定向的免疫测定装置的不同区域，以及一个或多个数字处理器（104a，104b）和 配置为从光学系统（121）接收数据和控制光学系统（121）并控制机电马达系统（106）的相关电子设备。

公开(公告)号：US20130243657A1

公开(公告)日：2013-09-19

申请号：US13988083

申请日：2011-10-19

Applicant: Keiko Yoshikawa ,  Hajime Yamazaki

Inventor： Keiko Yoshikawa ,  Hajime Yamazaki

IPC: G01N21/17

CPC classification number: G01N21/17 ,  F21Y2115/10 ,  G01N21/272 ,  G01N2021/3181 ,  G01N2035/00346 ,  G01N2201/0231 ,  G01N2201/0624 ,  G01N2201/0695 ,  G01N2201/1211

Abstract: An automatic analyzing apparatus which can make an adjustment to a target temperature so as to stabilize the light intensity of an LED and also can make the adjustment to that temperature in a short time is provided. The automatic analyzing apparatus in which an LED is used for a light source 114 includes a temperature adjusting mechanism 201 for the LED, and the temperature adjusting mechanism 201 includes a metal member 202 provided with the light source 114, a pair of metal pipes (water-flowing pipes) 203 buried in the metal member 202 and allowing constant-temperature bath water to flow therein, and pins (small metal piece members) 204 bringing only a heat-generating lead 252 of the light source 114 into direct contact with the metal member 202. Therefore, the temperature adjusting mechanism 201 can make an adjustment to a target temperature so as to stabilize the light intensity of the LED, and the adjustment to that temperature can be made in a short time.

Abstract translation: 一种自动分析装置，其可以对目标温度进行调节，以稳定LED的光强度，并且还可以在短时间内对该温度进行调节。 其中LED用于光源114的自动分析装置包括用于LED的温度调节机构201，温度调节机构201包括设置有光源114的金属构件202，一对金属管（水 埋入金属构件202中并允许恒温槽水流入其中的引脚（小金属构件）204，仅使光源114的发热引线252与金属直接接触 因此，温度调节机构201可以调节目标温度以稳定LED的光强度，并且可以在短时间内对该温度进行调节。

公开(公告)号：US20110057120A1

公开(公告)日：2011-03-10

申请号：US12593092

申请日：2009-06-05

Applicant: Heinrich Ostendarp ,  Siegfried Piontek

Inventor： Heinrich Ostendarp ,  Siegfried Piontek

IPC: G01N21/64 ,  G01N21/958

CPC classification number: G01N21/645 ,  G01N21/896 ,  G01N21/94 ,  G01N2201/0624 ,  G01N2201/0625

Abstract: An apparatus for determining element occupancy on a surface includes a UV beam source comprising at least one UV light-emitting diode whose UV radiation excites the element to fluorescence and a detector unit for the detection of fluorescence radiation. The apparatus, in accordance with the invention, is characterized in that beam guidance is configured by alignment of the UV beam source and the detector unit relative to the surface and/or by using a wavelength-selective beam splitter in the beam path in such a manner that the UV radiation back-reflected from the surface is kept away from the detector unit.

Abstract translation: 用于确定表面上的元件占用的装置包括UV束源，其包括至少一个紫外线发射二极管，其UV辐射将元件激发到荧光，以及用于检测荧光辐射的检测器单元。 根据本发明的装置的特征在于，通过UV光源和检测器单元相对于表面的对准和/或通过在波束路径中使用波长选择性分束器来配置光束引导 使得从表面反向反射的UV辐射远离检测器单元的方式。

公开(公告)号：US20100187450A1

公开(公告)日：2010-07-29

申请号：US12665068

申请日：2008-06-18

Applicant: Josephus Arnoldus Henricus Maria Kahlman ,  Coen Adrianus Verschuren

Inventor： Josephus Arnoldus Henricus Maria Kahlman ,  Coen Adrianus Verschuren

IPC: G01J3/50 ,  G01N15/06 ,  H01J3/14

CPC classification number: G01N21/552 ,  G01N21/274 ,  G01N21/4788 ,  G01N21/648 ,  G01N2021/0378 ,  G01N2201/0624 ,  G01N2201/0625 ,  G01N2201/124

Abstract: The invention relates to a method and a microelectronic sensor device for making optical examinations in an investigation region (3). An input light beam (L1) is emitted by a light source (20) into said investigation region (3), and an output light beam (L2) coming from the investigation region (3) is detected by a light detector (30) providing a measurement signal (X). An evaluation unit (40) provides a result signal (R) based on a characteristic parameter (e.g. the intensity) of the input light beam (L1) and the output light beam (L2). Preferably, the input light beam (L1) is modulated with a given frequency (ω) and monitored with a sensor unit (22) that provides a monitoring signal (M). The monitoring signal (M) and the measurement signal (X) can then be demodulated with respect to the monitoring signal, and their ratio can be determined. This allows to obtain a result signal (R) that is largely independent of environmental influences and variations in the light source.

Abstract translation: 本发明涉及一种用于在调查区域（3）进行光学检查的方法和微电子传感器装置。 输入光束（L1）由光源（20）发射到所述调查区域（3）中，来自调查区域（3）的输出光束（L2）由光检测器（30）检测，提供 测量信号（X）。 评估单元（40）基于输入光束（L1）和输出光束（L2）的特征参数（例如强度）提供结果信号（R）。 优选地，以给定频率（ω）调制输入光束（L1），并用提供监视信号（M）的传感器单元（22）监视输入光束（L1）。 监测信号（M）和测量信号（X）可以相对于监视信号被解调，并且可以确定其比例。 这允许获得在很大程度上独立于光源的环境影响和变化的结果信号（R）。

公开(公告)号：US20080304048A1

公开(公告)日：2008-12-11

申请号：US12095326

申请日：2006-11-28

Applicant: Stig Tormod

Inventor： Stig Tormod

IPC: G01N21/33 ,  G01N21/59

CPC classification number: G01N21/33 ,  G01N21/05 ,  G01N21/274 ,  G01N30/74 ,  G01N2021/0193 ,  G01N2030/746 ,  G01N2201/062 ,  G01N2201/0624 ,  G01N2201/0639

Abstract: The present invention relates to methods and apparatus for detecting and measuring the concentration of a substance in a solution, the substance having an absorption at 300 nm or less. The methods and apparatus have particular utility in detecting and measuring the concentration of proteins and nucleic acids.

Abstract translation: 本发明涉及用于检测和测量溶液中物质浓度的方法和装置，该物质在300nm以下具有吸收。 该方法和装置在检测和测量蛋白质和核酸的浓度方面具有特殊的用途。

公开(公告)号：US07390665B2

公开(公告)日：2008-06-24

申请号：US10378797

申请日：2003-03-04

Applicant: Steven B. Gilmour ,  Brent E. Modzelewski

Inventor： Steven B. Gilmour ,  Brent E. Modzelewski

IPC: G01N35/00 ,  G01N15/06 ,  G01N33/00 ,  G01N33/48 ,  C12Q1/68

CPC classification number: G01N21/8483 ,  G01N21/78 ,  G01N33/54386 ,  G01N35/00594 ,  G01N35/00712 ,  G01N35/0092 ,  G01N2035/00108 ,  G01N2201/062 ,  G01N2201/0621 ,  G01N2201/0624 ,  G01N2201/0625 ,  G01N2201/0694 ,  Y10T436/10 ,  Y10T436/110833

Abstract: A method and apparatus for automatically selecting test types for an analytical meter system based on the insertion into the meter of a test element. The test element can be an analytical element, formed by a test strip with a fluid such as blood applied thereto; a control element, formed by a test strip with control fluid applied thereto; or a standard element, or a standard strip exhibiting known optical properties. By inserting the test element into the analytical meter system, optical properties are measured and the existence of relationships between the measurements are ascertained. Based on the existence or nonexistence of certain relationships, the proper test can be automatically selected by the meter without the need for user interaction. Advantageously, the results of the test can be classified and stored according to test type.

Abstract translation: 一种用于根据插入测试元件的仪表自动选择分析仪表系统的测试类型的方法和装置。 测试元件可以是由测试条形成的分析元件，所述测试条带有施加于其上的诸如血液的流体; 由控制流体施加到其上的测试条形成的控制元件; 或标准元件，或具有已知光学性质的标准条。 通过将测试元件插入分析仪表系统，测量光学性质，并确定测量之间的关系的存在。 基于某些关系的存在或不存在，仪表可以自动选择正确的测试，而无需用户交互。 有利地，可以根据测试类型对测试结果进行分类和存储。