公开(公告)号：US20170016890A1

公开(公告)日：2017-01-19

申请号：US15124076

申请日：2015-03-05

Applicant: PAIA BIOTECH GMBH

Inventor： Sebastian GIEHRING

IPC: G01N33/543 ,  G01N21/64 ,  B01L3/00

CPC classification number: G01N33/54326 ,  B01L3/5025 ,  B01L3/5085 ,  B01L2200/0647 ,  B01L2200/0668 ,  B01L2300/0654 ,  B01L2300/0829 ,  B01L2300/0848 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/0887 ,  B01L2300/168 ,  B01L2400/0409 ,  B01L2400/043 ,  B01L2400/0457 ,  G01N21/0303 ,  G01N21/6428 ,  G01N21/6452 ,  G01N33/54366 ,  G01N2021/6439 ,  G01N2021/6482 ,  G01N2201/0642

Abstract: The invention relates to a method for quantitatively determining biological analytes in an aqueous solution in the presence of one or more functionalised surfaces, wherein the aqueous solution comprises at least one type of biological analyte and at least one type of fluorescence marker, characterised in that the quantity and/or concentration of the biological analyte or analytes is determined by measuring the fluorescence emission of the unbound fluorescence markers, as well as to a devices for carrying out said method.

Abstract translation: 本发明涉及在一种或多种官能化表面存在下定量测定水溶液中生物分析物的方法，其中所述水溶液包含至少一种类型的生物分析物和至少一种类型的荧光标记物，其特征在于， 通过测量未结合荧光标记物的荧光发射以及用于实施所述方法的装置来确定生物分析物或分析物的量和/或浓度。

公开(公告)号：US09528932B2

公开(公告)日：2016-12-27

申请号：US14761378

申请日：2014-01-16

Applicant: Westboro Photonics

Inventor： Tim Moggridge

IPC: G01N21/00 ,  G01N21/47

CPC classification number: G01N21/4738 ,  G01N2201/0642 ,  G01N2201/065

Abstract: The invention relates to a light integrating cavity device, such as an integrating sphere, for measuring diffuse reflectance of a sample. A light trap is movable within a light scattering cavity of the device for controlling specular reflections during measurements. The light trap may be rotatable around the sample under test inside the cavity so that specular reflections off the sample can be included or excluded from the measurement. The sample may also be placed at the outside against a measurement port, and a measurement instrument is moveable on a rotating arm within or outside of the cavity.

Abstract translation: 本发明涉及一种用于测量样品的漫反射率的光积分腔装置，例如积分球。 光阱可在器件的光散射腔内移动，用于在测量期间控制镜面反射。 光阱可以在空腔内围绕被测试样品旋转，使得样品的镜面反射可以包含或排除在测量之外。 样品也可以放置在外部抵靠测量端口，并且测量仪器可以在空腔内部或外部的旋转臂上移动。

公开(公告)号：US09389188B2

公开(公告)日：2016-07-12

申请号：US14704007

申请日：2015-05-05

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Dmitri Simonian ,  Mikhail Fouksman

IPC: G01N21/64 ,  G01N21/896 ,  G01N21/89

CPC classification number: G01N21/896 ,  G01N21/8901 ,  G01N2201/0642

Abstract: A structure for testing a luminescent film includes a Lambertian light source, an integrating sphere having an input port, and a measuring device. The Lambertian light source includes a mixing chamber having an input port and an output port, and a light emitter coupled to the input port. During testing the luminescent film is positioned between the output port of the mixing chamber and the input port of the integrating sphere. The measuring device is optically coupled to the integrating sphere.

Abstract translation: 用于测试发光膜的结构包括朗伯光源，具有输入端口的积分球和测量装置。 朗伯光源包括具有输入端口和输出端口的混合室以及耦合到输入端口的光发射器。 在测试期间，发光膜位于混合室的输出端口和积分球的输入端口之间。 测量装置光学耦合到积分球。

公开(公告)号：US20160153886A1

公开(公告)日：2016-06-02

申请号：US14951501

申请日：2015-11-25

Applicant: HACH LANGE GMBH

Inventor： BAS DE HEIJ ,  PERRY PALUMBO

IPC: G01N15/14

CPC classification number: G01N15/1404 ,  G01N15/1436 ,  G01N21/05 ,  G01N21/53 ,  G01N33/18 ,  G01N2201/0642

Abstract: A nephelometric process turbidimeter for measuring a turbidity of a liquid sample includes a transparent sample vial which comprises a sample vial lateral inner surface. A vial head comprises a vial head lateral inner surface. The vial head and the sample vial together define a sample volume of a liquid sample having a shape of a cylinder. A sample inlet opening is arranged at the vial head and comprises an inlet opening axis. A sample outlet opening is arranged at the cylindrical vial head lateral inner surface to be axially closer to the sample vial than to the sample outlet opening. The inlet opening axis is inclined with respect to an inlet cross plane with an inclination angle of 10° to 80°, and is angled with respect to a radius line from a middle of the cylinder to the sample inlet opening with a tangency angle of more than 15°.

Abstract translation: 用于测量液体样品的浊度的比浊法工艺浊度计包括透明样品瓶，其包括样品瓶横向内表面。 小瓶头包括小瓶头侧面内表面。 样品瓶头和样品瓶一起限定了具有圆筒形状的液体样品的样品体积。 样品入口开口布置在小瓶头部并且包括入口开口轴线。 样品出口开口布置在圆柱形瓶头横向内表面上，以轴向更靠近样品瓶而不是样品出口。 入口开口轴线相对于倾斜角度为10°至80°的入口横截面倾斜，并且相对于从圆柱体的中部到样品入口开口的半径线成角度，具有更多的相切角度 超过15°。

公开(公告)号：US20160091365A1

公开(公告)日：2016-03-31

申请号：US14501544

申请日：2014-09-30

Applicant: PerkinElmer Health Sciences, Inc.

Inventor： Joseph L. DiCesare ,  Feng Jin ,  Timothy P. Neal ,  David Aikens

IPC: G01J3/02 ,  G01J3/44 ,  G02B6/26

CPC classification number: G01J3/0202 ,  G01J3/0218 ,  G01J3/4406 ,  G01N21/05 ,  G01N21/645 ,  G01N2021/0389 ,  G01N2021/6417 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/0642 ,  G01N2201/0826 ,  G01N2201/0833 ,  G02B6/262

Abstract: A flow cell for a fluorescence spectrometer includes a flow channel to receive a flow of a liquid sample, an excitation light entrance window to receive excitation light from a light source, and an emission light exit window to transmit fluorescent emission light from the liquid sample in the flow channel from the flow cell. The excitation light entrance window and/or emission light exit window includes a waveguide including: a waveguide core formed of a core material; and a cladding medium surrounding a portion of the waveguide core, wherein the cladding medium has a refractive index less than the refractive index of the core material. The waveguide defines a portion of the flow channel.

Abstract translation: 用于荧光光谱仪的流动池包括用于接收液体样品流动的流动通道，用于接收来自光源的激发光的激发光入射窗口和用于从液体样品透射荧光发射光的发射光出射窗口 来自流动池的流动通道。 激发光入射窗口和/或发射光出射窗口包括波导，包括：由芯材形成的波导芯; 以及围绕所述波导芯的一部分的包层介质，其中所述包层介质具有小于所述芯材料的折射率的折射率。 波导限定了流动通道的一部分。

公开(公告)号：US20150204841A1

公开(公告)日：2015-07-23

申请号：US14421037

申请日：2013-07-09

Applicant: OBSCHESTVO OGRANICHENNOY OTVETSTVENNOSTYU << GEMATOLOGICHESKAYA KORPORATSIYA>>

Inventor： Fazoil Inoyatovich Ataullakhanov ,  Vasilii Ivanovich Sarbash ,  Mikhail Aleksandrovich Panteleev ,  Sergey Sergeevich Karamzin

IPC: G01N33/49 ,  B01L99/00

CPC classification number: G01N33/49 ,  B01L99/00 ,  B01L2300/14 ,  B01L2300/185 ,  C12Q1/56 ,  G01N21/0332 ,  G01N21/82 ,  G01N2201/0642

Abstract: The invention relates to the field of medicine and biology. A device for monitoring of spatial coagulation of blood and its uses for diagnostic and research purposes is described. The device includes a thermostatically controlled chamber, at least one means of illumination, a means of recording connected to the thermostatically controlled chamber. The thermostatically controlled chamber includes a cuvette to place a sample of a test medium, a light trap, and is filled with a substance suitable for temperature regulation. The light trap is formed by geometry of the inner surfaces of the thermostatically controlled chamber.

Abstract translation: 本发明涉及医学和生物学领域。 描述了用于监测血液的空间凝血及其用于诊断和研究目的的用途的装置。 该装置包括恒温控制室，至少一个照明装置，连接到恒温控制室的记录装置。 恒温控制室包括用于放置测试介质，光阱的样品的比色皿，并且填充有适于温度调节的物质。 光阱由恒温控制室的内表面的几何形状形成。

公开(公告)号：US20150192493A1

公开(公告)日：2015-07-09

申请号：US14408455

申请日：2013-04-30

Applicant: TOYO SEIKAN GROUP HOLDINGS, LTD.

Inventor： Yasuhiro Kouji ,  Yuuma Ishii ,  Tomoki Seo

IPC: G01M3/38 ,  G01N21/90 ,  G01N21/894

CPC classification number: G01M3/38 ,  G01N21/894 ,  G01N21/909 ,  G01N2201/062 ,  G01N2201/0642

Abstract: Provided is a pinhole inspection apparatus for can bodies capable of effectively preventing entrance of ambient light to a photodetector side through a gap between a movable plate and a rotating turret that may be formed due to a surface condition or the like. The pinhole inspection apparatus of the present invention includes: a rotating turret having a penetrating through hole; a movable plate provided on a stationary frame opposite the rotating turret; a can body holding member supporting a can body; a photodetector detecting light leaking inside the can body; and a light source irradiating the can body with light. The pinhole inspection apparatus is characterized in that a detour path formed by a pair of shield parts spaced apart a predetermined distance and opposite from each other is provided as a shield mechanism in an entire outer peripheral region of the rotating turret.

Abstract translation: 本发明提供一种用于罐体的针孔检查装置，其能够有效地防止环境光通过由于表面状况等而形成的可动板和旋转转台之间的间隙而进入光电检测器侧。 本发明的针孔检查装置包括：具有贯通孔的旋转转台; 设置在与所述旋转转台相对的固定框架上的可动板; 支撑罐体的罐体保持构件; 检测在罐体内部泄漏的光的光检测器; 以及用光照射罐体的光源。 针孔检查装置的特征在于，在旋转转台的整个外周区域中设置由隔开预定距离并相互相对的一对屏蔽部件形成的迂回路径作为屏蔽机构。

公开(公告)号：US08976362B2

公开(公告)日：2015-03-10

申请号：US13570100

申请日：2012-08-08

Applicant: John G. Hagopian ,  Stephanie A. Getty ,  Manuel A. Quijada

Inventor： John G. Hagopian ,  Stephanie A. Getty ,  Manuel A. Quijada

IPC: G01N21/47

CPC classification number: C23C16/26 ,  B82Y30/00 ,  B82Y40/00 ,  C23C16/0281 ,  G01N2201/0642

Abstract: A system, apparatus and method employing carbon nanotubes on substrates such as silicon, titanium, copper, stainless steel and other substrates, where the carbon nanotubes are blacker than existing paints and coatings, thereby providing an exponential increase in stray light suppression depending on the number of bounces of such treated surfaces. Additionally, the present invention is directed to techniques to better absorb and radiate unwanted energies. Further, the alternate substrates offer strength of material for numerous components and in numerous physical applications. The present invention is also directed to techniques for improving the adhesion of the nanotubes to the alternate substrate materials and also extending the wavelength of operation from the near ultraviolet to the far infrared portion of the spectrum (0.2 microns to 120 microns wavelength).

Abstract translation: 在诸如硅，钛，铜，不锈钢和其他基底的基底上使用碳纳米管的系统，设备和方法，其中碳纳米管比现有的涂料和涂层更黑，从而根据数量提供杂散光抑制的指数增加 的这种处理表面的反弹。 另外，本发明涉及更好地吸收和辐射不需要的能量的技术。 此外，替代的基板提供了许多部件和许多物理应用中的材料的强度。 本发明还涉及用于改善纳米管与替代的基底材料的粘合性并且还将波长的波长从光谱的近紫外到远红外部分延伸（0.2微米到120微米波长）的技术。

公开(公告)号：US08705030B2

公开(公告)日：2014-04-22

申请号：US13085343

申请日：2011-04-12

Applicant: Yang Zhou ,  Zefei Jiang ,  Jinhong Qiu

Inventor： Yang Zhou ,  Zefei Jiang ,  Jinhong Qiu

IPC: G01J3/28

CPC classification number: G01N21/01 ,  G01N21/31 ,  G01N2201/06 ,  G01N2201/0642

Abstract: An optical sample detection system is provided, including a light source; a convergence projection component for converging light rays emitted by the light source; a sample accommodation component for accommodating a detected sample; a light beam collection component for receiving light rays carrying sample characteristic information and transmitted from the sample accommodation component; a light splitting component for splitting polychromatic lights collected by the light beam collection component into independent spectrums or spectral bands; and a photoelectric detection component for receiving optical signals of different wavelengths separated through the light splitting component.

Abstract translation: 提供了一种光学样本检测系统，包括光源; 用于会聚由光源发射的光线的会聚投影部件; 用于容纳检测到的样本的样本容纳部件; 光束采集部件，用于接收携带样品特征信息并从样品容纳部件传输的光线; 用于将由光束收集部件收集的多色光分解成独立光谱或光谱带的光分离部件; 以及用于接收通过分光部件分离的不同波长的光信号的光电检测部件。

公开(公告)号：US20130242308A1

公开(公告)日：2013-09-19

申请号：US13822147

申请日：2011-09-02

Applicant: Ying'an Zhan ,  Wei Liu ,  Yinfei Wu ,  Fei Gao

Inventor： Ying'an Zhan ,  Wei Liu ,  Yinfei Wu ,  Fei Gao

IPC: G01N21/55

CPC classification number: G01N21/553 ,  G01N21/4738 ,  G01N21/8483 ,  G01N2201/0642

Abstract: A device for reading an assay test result on a test carrier comprises: a light-emitting element (5) for emitting and irradiating light onto corresponding one or more zones of the test carrier (3); a light-blocking element (12) for blocking the light mirror-reflected by the test carrier (3) from being irradiated on a photodetector (7); and a window (10), through which the light emitted from the light-emitting element (5) is irradiated onto the corresponding zones of the test carrier (3). In one preferred embodiment, the positions of the light-emitting element (5), the light-blocking element and the window (10) meet the function of S3≦>2*S7−S7*S2/S1, where S1 represents the vertical distance between the light-emitting element and the window; S2 represents the vertical height of the light-blocking element; S3 represents the vertical distance between the light-blocking element and the light-emitting element; and S7 represents the length of the window.

Abstract translation: 用于读取测试载体上的测定结果的装置包括：发光元件（5），用于发射和照射到测试载体（3）的相应一个或多个区域上的光; 用于阻挡由所述测试载体（3）反射的光的光阻元件（12）照射在光电检测器（7）上; 以及窗口（10），从发光元件（5）发射的光被照射到测试载体（3）的相应区域上。 在一个优选实施例中，发光元件（5），遮光元件和窗（10）的位置满足S3 @ 2 * S7-S7 * S2 / S1的功能，其中S1表示垂直 发光元件与窗之间的距离; S2表示遮光元件的垂直高度; S3表示遮光元件与发光元件之间的垂直距离; S7表示窗口的长度。