公开(公告)号：US4627284A

公开(公告)日：1986-12-09

申请号：US757165

申请日：1985-07-22

Applicant: Michael E. Gersh ,  Fritz Bien ,  Lawrence S. Bernstein

Inventor： Michael E. Gersh ,  Fritz Bien ,  Lawrence S. Bernstein

IPC: G01J1/16 ,  G01N21/31 ,  G01N21/33 ,  G01W1/00

CPC classification number: G01N21/33 ,  G01W1/00 ,  G01J1/1626 ,  G01N21/314 ,  G01N2201/0696 ,  G01N2201/0806

Abstract: An ultraviolet absorption hygrometer is provided including a source of pulsed ultraviolet radiation for providing radiation in a first wavelength region where water absorbs significantly and in a second proximate wavelength region where water absorbs weakly. Ultraviolet radiation in the first and second regions which has been transmitted through a sample path of atmosphere is detected. The intensity of the radiation transmitted in each of the first and second regions is compared and from this comparison the amount of water in the sample path is determined.

Abstract translation: 提供一种紫外线吸收式湿度计，其包括用于在水吸收显着的第一波长区域中提供辐射的脉冲紫外线辐射源，以及在弱吸收水的第二接近波长区域。 检测已经透过大气样本路径的第一和第二区域中的紫外线辐射。 比较在第一和第二区域中的每一个中发射的辐射的强度，并从该比较中确定样品路径中的水量。

公开(公告)号：US3963351A

公开(公告)日：1976-06-15

申请号：US567946

申请日：1975-04-14

Applicant: Britton Chance ,  Victor Legallais ,  John R. Sorge ,  Norman C. Graham, Jr.

Inventor： Britton Chance ,  Victor Legallais ,  John R. Sorge ,  Norman C. Graham, Jr.

IPC: G01J1/44 ,  G01J3/12 ,  G01N21/31 ,  G01J3/30 ,  G01J3/48

CPC classification number: G01N21/314 ,  G01J2001/444 ,  G01J2003/123 ,  G01N2021/3162 ,  G01N2021/3174 ,  G01N2021/4742 ,  G01N2021/6421 ,  G01N21/6408 ,  G01N2201/0621 ,  G01N2201/0806

Abstract: A multi-wavelength time-sharing apparatus usable in various different configurations of optical measuring equipment to provide a plurality of time-shared optical channels and including appropriate circuitry. The apparatus employs a turbine-driven filter wheel having a shaft position-encoding arrangement consisting of a hollow shaft portion which is internally illuminated. The hollow shaft portion has two sets of spaced apertures cyclically communicating with respective angularly spaced pairs of externally fixedly mounted phototransistors which are sequentially illuminated as the shaft portion rotates and which produce timing pulses which drive Schmitt triggers, which, in a typical embodiment, in turn produce pulses compatible with a logic circuit employed to decode the phototransistor signals into triggers for driving a 4-channel switched gain equalizer, a dark current clamp, and detector gates. Appropriate selection of the signals enables the instrument to function as a fluorometer or a spectrophotometer.

Abstract translation: 一种可用于各种不同配置的光学测量设备以提供多个时间共享的光学信道并且包括适当的电路的多波长时间共享装置。 该装置采用具有轴位置编码装置的涡轮驱动滤光轮，该轴位置编码装置由内部照明的中空轴部分组成。 空心轴部分具有两组间隔开的孔，这些孔与相应的有角度地间隔开的外部固定安装的光电晶体管对循环连通，随着轴部分旋转，该光电晶体管依次被照亮，并且产生驱动施密特触发器的定时脉冲，在典型的实施例中， 产生与用于将光电晶体管信号解码为用于驱动4通道开关增益均衡器，暗电流钳和检测器门的触发器的逻辑电路兼容的脉冲。 信号的适当选择使得仪器能够用作荧光计或分光光度计。

公开(公告)号：US20240060895A1

公开(公告)日：2024-02-22

申请号：US18496681

申请日：2023-10-27

Applicant: Illumina, Inc.

Inventor： Rui JIANG ,  Joseph PINTO

IPC: G01N21/64 ,  C12Q1/6869 ,  G01J3/10 ,  G02B27/09

CPC classification number: G01N21/6428 ,  C12Q1/6869 ,  G01J3/10 ,  G01N21/6452 ,  G01N21/6456 ,  G02B27/0994 ,  G01N2021/6419 ,  G01N2021/6439 ,  G01N2021/6463 ,  G01N2201/0638 ,  G01N2201/08 ,  G01N2201/0806 ,  H01L27/14612

Abstract: There is set forth herein a light energy exciter that can include one or more light sources. A light energy exciter can emit excitation light directed toward a detector surface that can support biological or chemical samples.

公开(公告)号：US09989465B2

公开(公告)日：2018-06-05

申请号：US15598236

申请日：2017-05-17

Applicant: TAIGEN BIOSCIENCE CORPORATION

Inventor： Hung-Jen Kao

IPC: F21V9/16 ,  G01N21/64 ,  C12Q1/68

CPC classification number: G01N21/6428 ,  C12Q1/686 ,  G01N21/645 ,  G01N2021/6419 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2201/0627 ,  G01N2201/0806

Abstract: The present invention provides a multi-channel fluorescence detecting system for detecting a plurality of fluorescence labeled analytes. The multi-channel fluorescence detecting system comprises a light source, a light filter device, a dual branch light guide tube, and a detector. The light source comprises a plurality of sub light sources for respectively providing an excitation light. The plurality of sub light sources are a plurality of single color Light emitting diodes (LEDs) which can be selectively turned on or off. The light source generates a plurality of lights with full width at half maximum (FWHM) wavelengths formed in a non-overlap manner. With the disposition of the plurality of sub light sources, the accuracy for detecting the specific analytes is raised, the light flux with a specific wavelength band is effectively raised (without raising the light flux of the full wavelength band), the structure is simplified, and the manufacturing cost is decreased.

公开(公告)号：US09835545B2

公开(公告)日：2017-12-05

申请号：US15046161

申请日：2016-02-17

Applicant: AZBIL CORPORATION

Inventor： Masashi Furuya ,  Daisuke Obara

IPC: G01N21/75 ,  G01N33/00 ,  G01N21/05 ,  G01N15/14 ,  G01N31/00 ,  G01N15/10 ,  G01N21/64

CPC classification number: G01N21/05 ,  G01N15/1436 ,  G01N15/1459 ,  G01N2015/1006 ,  G01N2021/6482 ,  G01N2201/0806

Abstract: A flow cell includes a transparent planar member having a first principal surface and a second principal surface opposite to the first principal surface. The planar member has a through-hole that has a circular cross-sectional shape and that penetrates through the first principal surface and the second principal surface. The flow cell further includes a first lens element having a through-hole that has a circular cross-sectional shape. The first lens element is disposed on the first principal surface of the planar member such that the through-hole in the planar member communicates with the through-hole in the first lens element. The flow cell further includes a second lens element having a through-hole that has a circular cross-sectional shape. The second lens element is disposed on the second principal surface of the planar member such that the through-hole in the planar member communicates with the through-hole in the second lens element.

公开(公告)号：US09784685B2

公开(公告)日：2017-10-10

申请号：US14566708

申请日：2014-12-10

Applicant: Molecular Devices, LLC

Inventor： Josef J. Atzler ,  Michael Katzlinger ,  Georg Kronberger ,  Bernhard Schinwald

IPC: G01N35/02 ,  G01N21/64 ,  G01N35/10 ,  G01J3/02 ,  G01N21/76 ,  G01J3/00 ,  G01N21/25

CPC classification number: G01N21/76 ,  G01J3/02 ,  G01N21/15 ,  G01N21/253 ,  G01N21/763 ,  G01N27/223 ,  G01N35/028 ,  G01N2021/015 ,  G01N2021/155 ,  G01N2035/1025 ,  G01N2201/0225 ,  G01N2201/0245 ,  G01N2201/0446 ,  G01N2201/0806

Abstract: In a sample analyzing apparatus, an injector assembly injects a reagent onto a sample, and luminescent light from the sample is transmitted to a detector. The assembly may be movable toward and away from the sample. The assembly may include one or more needles that communicate with one or more reservoirs supplying reagent or other liquids. The assembly may include a light guide for communicating with the detector. A cartridge may be provided in which the assembly, one or more reservoirs, and one or more pumps are disposed. The cartridge and/or the apparatus may be configured for enabling rinsing or priming to be done outside the apparatus. The cartridge and/or the apparatus may include one or more types of sensors configured for detecting, for example, the presence of liquid or bubbles in one or more locations of the apparatus and/or the cartridge.

公开(公告)号：US20160238517A1

公开(公告)日：2016-08-18

申请号：US15046161

申请日：2016-02-17

Applicant: AZBIL CORPORATION

Inventor： Masashi FURUYA ,  Daisuke OBARA

IPC: G01N21/05 ,  G01N15/14

CPC classification number: G01N21/05 ,  G01N15/1436 ,  G01N15/1459 ,  G01N2015/1006 ,  G01N2021/6482 ,  G01N2201/0806

Abstract: A flow cell includes a transparent planar member having a first principal surface and a second principal surface opposite to the first principal surface. The planar member has a through-hole that has a circular cross-sectional shape and that penetrates through the first principal surface and the second principal surface. The flow cell further includes a first lens element having a through-hole that has a circular cross-sectional shape. The first lens element is disposed on the first principal surface of the planar member such that the through-hole in the planar member communicates with the through-hole in the first lens element. The flow cell further includes a second lens element having a through-hole that has a circular cross-sectional shape. The second lens element is disposed on the second principal surface of the planar member such that the through-hole in the planar member communicates with the through-hole in the second lens element.

Abstract translation: 流动池包括具有第一主表面和与第一主表面相对的第二主表面的透明平面构件。 平面构件具有贯通第一主表面和第二主表面的圆形横截面形状的通孔。 流动池还包括具有圆形横截面形状的通孔的第一透镜元件。 第一透镜元件设置在平面构件的第一主表面上，使得平面构件中的通孔与第一透镜元件中的通孔连通。 流通池还包括具有圆形横截面形状的通孔的第二透镜元件。 第二透镜元件设置在平面构件的第二主表面上，使得平面构件中的通孔与第二透镜元件中的通孔连通。

公开(公告)号：US09212999B2

公开(公告)日：2015-12-15

申请号：US14396388

申请日：2013-03-12

Applicant: AVL EMISSION TEST SYSTEMS GMBH

Inventor： Norbert Kreft

IPC: G01N21/76 ,  G01N33/00

CPC classification number: G01N21/766 ,  G01N33/0037 ,  G01N2201/0636 ,  G01N2201/0806 ,  G01N2201/084 ,  G01N2201/0846 ,  Y02A50/245

Abstract: A device for determining a concentration of at least one gas in a sample gas stream includes an analysis chamber, a detector, and a connecting channel. The analysis chamber is configured to have the sample gas stream and a reaction gas stream be introduced therein. The sample gas stream and the reaction gas stream are mixed to a gas mixture which reacts so as to emit an optical radiation. The detector is configured to measure the optical radiation. The connecting channel is configured to connect the analysis chamber to the detector. The connecting channel is configured as a light conductor extending from the analysis chamber to the detector.

Abstract translation: 用于确定样品气流中的至少一种气体的浓度的装置包括分析室，检测器和连接通道。 分析室被构造成具有样品气流并且反应气流被引入其中。 将样品气流和反应气流混合到反应以发射光辐射的气体混合物中。 检测器被配置成测量光辐射。 连接通道被配置为将分析室连接到检测器。 连接通道被配置为从分析室延伸到检测器的光导体。

公开(公告)号：US20130141715A1

公开(公告)日：2013-06-06

申请号：US13703414

申请日：2011-05-20

Applicant: Yuta Urano ,  Shigenobu Maruyama ,  Toshiyuki Nakao ,  Toshifumi Honda ,  Yukihiro Shibata

Inventor： Yuta Urano ,  Shigenobu Maruyama ,  Toshiyuki Nakao ,  Toshifumi Honda ,  Yukihiro Shibata

IPC: G01N21/88

CPC classification number: G01N21/94 ,  G01N21/47 ,  G01N21/8806 ,  G01N21/9501 ,  G01N21/956 ,  G01N2021/4711 ,  G01N2021/8867 ,  G01N2021/8874 ,  G01N2201/0806 ,  G01N2201/10

Abstract: Proposed is a defect inspection method whereby: illuminating light having a substantially uniform illumination intensity distribution in one direction of a sample surface irradiated on the sample surface; multiple scattered light components, which are output in multiple independent directions, are detected among the scattered light from the sample surface and multiple corresponding scattered light detection signals are obtained; at least one of the multiple scattered light detection signals is processed and the presence of defects is determined; at least one of the multiple scattered light detection signals that correspond to each of the points determined by the processing as a defect is processed and the dimensions of the defect are determined; and the position and dimensions of the defect on the sample surface, at each of the points determined as a defect, are displayed.

Abstract translation: 提出了一种缺陷检查方法，其中：照射在样品表面上的样品表面的一个方向具有基本上均匀的照明强度分布的光; 在来自样品表面的散射光中检测多个独立方向输出的多个散射光分量，并获得多个相应的散射光检测信号; 处理多个散射光检测信号中的至少一个并确定缺陷的存在; 处理与通过处理确定的每个点对应的多个散射光检测信号中的至少一个作为缺陷，并确定缺陷的尺寸; 并且显示在被确定为缺陷的每个点处的样品表面上的缺陷的位置和尺寸。

公开(公告)号：US20110273547A1

公开(公告)日：2011-11-10

申请号：US12776797

申请日：2010-05-10

Applicant: Shaohong Wang ,  Carlos Barnes Gonzalez

Inventor： Shaohong Wang ,  Carlos Barnes Gonzalez

IPC: H04N7/18

CPC classification number: G01N21/6458 ,  G01N21/64 ,  G01N2201/0806

Abstract: A method and an apparatus for imaging a biologic sample is provided. The apparatus includes at least one light source, at least one lens array, at least one image detector, a positioning system, and an image processor. The lens array has a plurality of lengthwise extending rows, which rows are successively arranged in a widthwise direction. Each row has a plurality of micro lenses, with each micro lens having a resolution field. Each micro lens is adapted to receive light from the illuminated region of the sample and to produce a beam of light. Each row includes a first micro lens and the first micro lens in each successive row is offset from the first micro lens in the previous row by a predetermined amount extending in the lengthwise direction. The offset between successive rows aligns the resolution fields of the micro lenses to collectively create a continuous resolution field across the length of the lens array. The positioning system moves the lens array and image detector relative to the sample, or vice versa, or both. The image processor produces an image signal indicative of the illuminated region of the sample produced from data signals from the image detector.

Abstract translation: 提供了一种生物样品成像方法和装置。 该装置包括至少一个光源，至少一个透镜阵列，至少一个图像检测器，定位系统和图像处理器。 透镜阵列具有多个纵向延伸的行，这些行在宽度方向上连续布置。 每行具有多个微透镜，每个微透镜具有分辨率场。 每个微透镜适于接收来自样品的照射区域的光并产生光束。 每行包括第一微透镜，并且每个连续行中的第一微透镜在前一行中偏离了在长度方向上延伸的预定量的第一微透镜。 连续行之间的偏移将微透镜的分辨率场对准以在透镜阵列的长度上共同形成连续的分辨率场。 定位系统相对于样品移动透镜阵列和图像检测器，反之亦然，或两者都相同。 图像处理器产生指示从图像检测器的数据信号产生的样本的照明区域的图像信号。