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61.发明授权
公开(公告)号：EP0655128B1
公开(公告)日：1998-03-18
申请号：EP93917790.3
申请日：1993-08-13
Applicant: Hewlett-Packard Company
Inventor： Mächler, Meinrad
IPC: G01J3/02
CPC classification number: G01N21/0303 , G01J3/02 , G01J3/0216 , G01N2201/0813 , G01N2201/084
Abstract: A spectroscopic system for the analysis of small and very small quantities of substances makes use for the purposes of energy transfer of cone-shaped aperture changers (14, 15) which are arranged in the object zone (8) between the light source (L) and the sample (9) and, during absorption measurements, also between the sample (9) and the inlet slot (3) of a spectrometer (1). If the form used is a double cone, the aperture changers (14, 15) facilitate an oblique coupling in a capillary tube accepting the sample (9) which acts as a step-waveguide for the coupled radiation.
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62.发明授权公开(公告)号：US12097491B2
公开(公告)日：2024-09-24
申请号：US17049849
申请日：2019-04-12
Applicant: Meon Medical Solutions GmbH & Co KG
Inventor： Herfried Huemer , Arnold Bartel , Patrick Kraus-Füreder , Robert Scholz-Mareich , Wolfgang Sprengers , Michael Bergbaur , Reinhard Marik
CPC classification number: B01L3/0289 , G01N21/59 , G01N35/026 , G01N35/1002 , G01N35/109 , B01L2200/14 , G01N2035/00356 , G01N2035/0437 , G01N2201/0631 , G01N2201/0813
Abstract: Aspects of the present disclosure are directed to a method and a device for carrying out chemical, biochemical and/or immunochemical analyses of liquid samples, which are present in a sample store of an automatic analyzer, with the aid of liquid reagents, which are present in at least one reagent store of the analyzer. In one embodiment, a analyzer is disclosed including cuvettes for holding the liquid samples and reagents, the cuvettes are arranged in at least one stationary, linear cuvette array. The analyzer further has an optical measurement unit with a stationary light-supplying unit which has at least one light distributor device that feeds the light from a plurality of LED light sources emitting in a spectrally different manner in the UV/VIS/NIR wavelength range into the inlet windows of the individual cuvettes of the cuvette array. The optical measurement unit further includes a stationary detection unit assigned to outlet windows of the cuvettes and further includes a plurality of photodiodes.
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公开(公告)号：US07403281B2
公开(公告)日：2008-07-22
申请号：US10859372
申请日：2004-06-01
Applicant: Keith T. Carron , Mark A. Watson , Shane A. Buller
Inventor： Keith T. Carron , Mark A. Watson , Shane A. Buller
IPC: G01J3/44
CPC classification number: G01J3/02 , G01J3/0272 , G01J3/0291 , G01J3/44 , G01J2003/4424 , G01N21/65 , G01N2201/0221 , G01N2201/0612 , G01N2201/0813
Abstract: A system, method and apparatus for taking a Raman spectrum of a sample is disclosed. In one embodiment, for example, an integrated Raman spectrometer is provided. In another embodiment, a portable Raman spectrometer is provided. In another embodiment, a Raman spectrometer is provided comprising a collimated beam tube for transmitting excitation radiation to an external optical system, such as a microscope, a telescope or a camera lens. In another embodiment, a method for correcting a Raman spectrum for background interference is provided. In yet another embodiment, a method for rejecting fluorescence in a Raman spectrometer is provided. A chemical reactor comprising a built-in Raman detector for monitoring a chemical reaction in a reaction chamber of the reactor is also provided.
Abstract translation: 公开了一种用于获取样品的拉曼光谱的系统，方法和装置。 在一个实施例中，例如，提供了一种集成的拉曼光谱仪。 在另一个实施例中，提供了便携式拉曼光谱仪。 在另一个实施例中，提供拉曼光谱仪，其包括用于将激发辐射传输到诸如显微镜，望远镜或相机透镜的外部光学系统的准直束管。 在另一实施例中，提供了用于校正背景干扰的拉曼光谱的方法。 在另一个实施方案中，提供了一种用于在拉曼光谱仪中排除荧光的方法。 还提供了一种包括用于监测反应器的反应室中的化学反应的内置拉曼检测器的化学反应器。
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64.发明申请公开(公告)号：US20070071357A1
公开(公告)日：2007-03-29
申请号：US11558593
申请日：2006-11-10
Applicant: John Rahn , Alan Nelson
Inventor： John Rahn , Alan Nelson
CPC classification number: G02B21/26 , G01N15/1468 , G01N15/147 , G01N15/1475 , G01N21/05 , G01N21/4795 , G01N2015/1006 , G01N2015/1075 , G01N2021/0346 , G01N2021/1787 , G01N2201/0813 , G01N2223/612 , G02B21/365 , G06T11/005 , G06T11/006 , G06T2211/412 , G06T2211/421
Abstract: An apparatus and method for correction of relative object-detector motion between successive views during optical tomographic imaging in three dimensions. An object of interest is illuminated to produce an image. A lateral offset correction value is determined for the image. An axial offset correction value is determined for the image. The lateral offset correction value and the axial offset correction value are applied to the image to produce a corrected file image.
Abstract translation: 一种用于在三维尺度下在光学层析成像期间校正连续视图之间的相对物体检测器运动的装置和方法。 感兴趣的对象被照亮以产生图像。 确定图像的横向偏移校正值。 为图像确定轴向偏移校正值。 将横向偏移校正值和轴向偏移校正值应用于图像以产生校正的文件图像。
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公开(公告)号：US20050248758A1
公开(公告)日：2005-11-10
申请号：US10859372
申请日：2004-06-01
Applicant: Keith Carron , Mark Watson , Shane Buller
Inventor： Keith Carron , Mark Watson , Shane Buller
CPC classification number: G01J3/02 , G01J3/0272 , G01J3/0291 , G01J3/44 , G01J2003/4424 , G01N21/65 , G01N2201/0221 , G01N2201/0612 , G01N2201/0813
Abstract: A system, method and apparatus for taking a Raman spectrum of a sample is disclosed. In one embodiment, for example, an integrated Raman spectrometer is provided. In another embodiment, a portable Raman spectrometer is provided. In another embodiment, a Raman spectrometer is provided comprising a collimated beam tube for transmitting excitation radiation to an external optical system, such as a microscope, a telescope or a camera lens. In another embodiment, a method for correcting a Raman spectrum for background interference is provided. In yet another embodiment, a method for rejecting fluorescence in a Raman spectrometer is provided. A chemical reactor comprising a built-in Raman detector for monitoring a chemical reaction in a reaction chamber of the reactor is also provided.
Abstract translation: 公开了一种用于获取样品的拉曼光谱的系统，方法和装置。 在一个实施例中，例如，提供了一种集成的拉曼光谱仪。 在另一个实施例中，提供了便携式拉曼光谱仪。 在另一个实施例中，提供拉曼光谱仪，其包括用于将激发辐射传输到诸如显微镜，望远镜或相机透镜的外部光学系统的准直束管。 在另一实施例中，提供了用于校正背景干扰的拉曼光谱的方法。 在另一个实施方案中，提供了一种用于在拉曼光谱仪中排除荧光的方法。 还提供了一种包括用于监测反应器的反应室中的化学反应的内置拉曼检测器的化学反应器。
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Patent Agency Ranking
66.发明授权Rheo-optical indexer and method of screening and characterizing arrays of materials 失效流变光学指纹仪和筛选和表征材料阵列的方法公开(公告)号：US06535284B1
公开(公告)日：2003-03-18
申请号：US09579338
申请日：2000-05-25
Applicant: Damian Hajduk , Eric Carlson
Inventor： Damian Hajduk , Eric Carlson
IPC: G01J400
CPC classification number: G01N21/21 , B01J2219/00286 , B01J2219/00315 , B01J2219/00585 , B01J2219/00659 , B01J2219/00707 , B01J2219/0072 , B01J2219/00745 , C40B40/18 , C40B60/14 , G01J4/04 , G01N2201/0813
Abstract: A method and apparatus for characterizing and screening an array of material samples is disclosed. The apparatus includes a sample block having a plurality of regions for containing the material samples, a polarized light source to illuminate the materials, an analyzer having a polarization direction different than the polarization direction of the polarized light source, and a detector for analyzing changes in the intensity of the light beams. The light source, together with a polarizer, may include a plurality of light beams to simultaneously illuminate the entire array of materials with linearly polarized light so that characterization and screening can be performed in parallel. In addition, the materials in the sample block maybe subjected to different environmental conditions or mechanical stresses, and the detector analyzes the array as a function of the different environmental conditions or mechanical stresses.
Abstract translation: 公开了一种表征和筛选材料样品阵列的方法和装置。 该装置包括具有用于容纳材料样本的多个区域的样本块，用于照射材料的偏振光源，具有与偏振光源的偏振方向不同的偏振方向的分析器，以及用于分析变化的检测器 光束的强度。 光源与偏振器一起可以包括多个光束，以同时以线性偏振光照射整个材料阵列，从而可以并行执行表征和筛选。 此外，样品块中的材料可能经受不同的环境条件或机械应力，并且检测器根据不同的环境条件或机械应力来分析阵列。
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67.发明授权Spectroscopic systems for the analysis of small and very small quantities of substance 失效用于分析小量和非常少量物质的光谱系统
公开(公告)号：US6108083A
公开(公告)日：2000-08-22
申请号：US907903
申请日：1997-08-11
Applicant: Meinrad Machler
Inventor： Meinrad Machler
CPC classification number: G01N21/0303 , G01J3/02 , G01J3/0216 , G01N2201/0813 , G01N2201/084
Abstract: A spectroscopic system for the analysis of small quantities of substances makes use for the purposes of energy transfer of cone-shaped aperture changers which are arranged in the object zone between the light source and the sample and, during absorption measurements, also between the sample and the inlet slot of a spectrometer. A microcell system is provided in the object space. The microcell system comprises a cylindrical cell tube with a hollow core for receiving a sample liquid. The cell tube and the sample liquid being adjustable with respect to the refractive index such that they act as a step waveguide for radiation, the sample liquid forming the core and the wall of the cell tube forming the sheath of the step waveguide.
Abstract translation: 用于分析少量物质的光谱系统用于锥形孔径变换器的能量转移的目的，锥形孔径变换器布置在光源和样品之间的物体区域中，并且在吸收测量期间也用于样品和 光谱仪的入口槽。 在对象空间中提供微小区系统。 微电池系统包括具有用于接收样品液体的中空芯的圆柱形电池管。 细胞管和样品液体相对于折射率可调节，使得它们用作辐射的步进波导，形成芯的样品液体和形成步进波导的护套的细胞管的壁。
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68.发明授权Spectroscopic systems for the analysis of small and very small quantities of substances 失效用于分析小量和非常少量物质的光谱系统
公开(公告)号：US5680209A
公开(公告)日：1997-10-21
申请号：US381911
申请日：1995-05-02
Applicant: Meinrad Machler
Inventor： Meinrad Machler
CPC classification number: G01N21/0303 , G01J3/02 , G01J3/0216 , G01N2201/0813 , G01N2201/084
Abstract: A spectroscopic system for the analysis of small and very small quantities of substances makes use for the purposes of energy transfer of cone-shaped aperture changers (14, 15) which are arranged in the object zone (8) between the light source (L) and the sample (9) and, during absorption measurements, also between the sample (9) and the inlet slot (3) of a spectrometer (1). If the form used is a double cone, the aperture changers (14, 15) facilitate an oblique coupling in a capillary tube accepting the sample (9) which acts as a step-waveguide for the coupled radiation.
Abstract translation: PCT No.PCT / EP93 / 02166 Sec。 371日期：1995年5月2日 102（e）日期1995年5月2日PCT提交1993年8月13日PCT公布。 出版物WO94 / 04892 日期1994年3月3日用于分析小量和非常少量物质的光谱系统用于锥形孔径变换器（14,15）的能量传递的目的，锥形孔径变换器（14,15）布置在物体区域（8）之间 光源（L）和样品（9），并且在吸收测量期间也在样品（9）和光谱仪（1）的入口槽（3）之间。 如果使用的形式是双锥形，则孔径更换器（14,15）有助于在接受用作耦合辐射的阶跃波导的样品（9）的毛细管中的倾斜耦合。
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公开(公告)号：US5155628A
公开(公告)日：1992-10-13
申请号：US382296
申请日：1989-07-20
Applicant: Andrew J. Dosmann
Inventor： Andrew J. Dosmann
CPC classification number: G02B27/108 , G01N21/255 , G02B27/1006 , G02B27/143 , G02B27/144 , G01N2021/1742 , G01N2201/0813
Abstract: An optical transmission spectrometer for transmission measurements of absorbing and scattering samples includes light sources mounted parallel to each other in a holder. The beams of light emanating from the light sources are directed through a beam-combiner. The beam-combiner includes a first refractive surface at an angle of incidence of 45.degree.. The first refractive surface refracts light toward a common axis. The beam-combiner includes a second refractive surface parallel to the first refractive surface for refracting the beam of light along a common axis parallel to the original direction of the beam of light. The beam-combiner can include additional refractive surfaces for other beams of light to combine the beams of light into a primary beam. The spectrometer includes a collimating tube extending along the common axis for baffling stray light and directing the primary beam through a sample. A second collimating tube is provided on the side of the sample opposite the first collimating tube for baffling stray light passing through the sample. The second collimating tube directs the primary beam to a detector package mounted in a holder, where the detector viewing area of the sample is limited to that of the primary beam. As an alternative, an optic which is capable of directing multiple light beams onto a common intersection point may be used in place of the previously mentioned beam-combiner. Unlike the beam-combiner which closely aligns multiple parallel light beams and transmits them as substantially a single beam along the common axis, the alternate optical directs multiple light beams at an angle onto a common intersection point. The optic is fabricated from translucent material with first and second refractive surfaces for receiving light beams from a source and refracting the light beams toward the common intersection point.
Abstract translation: 用于吸收和散射样品的透射测量的光学透射光谱仪包括在保持器中彼此平行地安装的光源。 从光源发出的光束被引导通过光束组合器。 光束组合器包括45°入射角的第一折射表面。 第一折射表面朝向公共轴线折射光。 光束组合器包括平行于第一折射表面的第二折射表面，用于沿着平行于光束的原始方向的公共轴折射光束。 光束组合器可以包括用于其他光束的附加折射表面，以将光束组合成主光束。 光谱仪包括沿公共轴延伸的准直管，用于挡板杂散光并将主光束引导通过样品。 第二准直管设置在与第一准直管相对的样品的侧面上，用于挡住通过样品的杂散光。 第二准直管将主光束引导到安装在保持器中的检测器封装，其中样品的检测器观察面积被限制为主光束的检测器观看面积。 作为替代，可以使用能够将多个光束引导到公共交叉点上的光学器件来代替先前提到的光束组合器。 与将多个平行光束紧密对准并将其作为基本上沿着公共轴线的单个光束传输的光束组合器不同，备选光学器件将多个光束以一定角度引导到公共交叉点上。 光学元件由具有第一和第二折射表面的半透明材料制成，用于接收来自源的光束并将光束折射到公共交叉点。
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公开(公告)号：US4368980A
公开(公告)日：1983-01-18
申请号：US162257
申请日：1980-06-23
Applicant: Phillip J. E. Aldred , Peter J. Taylor , Bryan W. Kenzie
Inventor： Phillip J. E. Aldred , Peter J. Taylor , Bryan W. Kenzie
CPC classification number: G01N21/3554 , G01N21/314 , G01N2201/0813
Abstract: The invention relates to apparatus for detecting water-based residues in translucent bottles, in which energy in two parts of the spectrum in and near the infra-red region, in one of which parts (0.8 to 0.9 microns) water is relatively transparent and the other of which parts (1.2 to 1.6 microns) water is more strongly absorbent is transmitted through a bottle, and the intensities of the emergent energies in the two parts are separately measured by a silicon detector and a germanium detector, associated with respective collimator tubes and filters, and are compared to produce a signal indicative of the presence of water in the bottle.
Abstract translation: 本发明涉及用于检测半透明瓶中的水基残留物的设备，其中红外区域内和附近的光谱的两部分中的能量在其中一个部分（0.8至0.9微米）的水中相对透明， 另一部分（1.2至1.6微米）的水更强吸收性透过瓶子，两部分的出射能的强度分别通过与各准直仪管相关联的硅检测器和锗检测器测量， 过滤器，并进行比较以产生指示瓶中存在水的信号。
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