公开(公告)号：WO1996022730A1

公开(公告)日：1996-08-01

申请号：PCT/US1996000866

申请日：1996-01-24

Applicant: OPTICAL SENSORS INCORPORATED

Inventor： OPTICAL SENSORS INCORPORATED ,  KIMBALL, Victor, E. ,  LYNCH, Laurie, E. ,  PIERSKALLA, Irvin, T. ,  PORTER, Christopher, H.

IPC: A61B05/05

CPC classification number: A61B5/157 ,  A61B5/14557 ,  A61B5/1495 ,  A61B5/15003 ,  A61B5/150992 ,  A61B5/155

Abstract: A method is provided for calibrating sensors (14) used to analyze characteristics of physiologic fluids such as blood. The method involves the use of a sensor assembly (12) having an analyte responsive sensor (14) in communication with a physiologic line (28) and a conduit passageway (16). The method involves exposing the sensor (14) to a reference sample, thereby producing a sensor response. The method also allows performing quality control on sensors (14). Also provided is an apparatus (10) with which the claimed method may be practiced.

Abstract translation: 提供了一种用于校准用于分析生理液体如血液的特征的传感器（14）的方法。 该方法涉及使用具有与生理线路（28）和导管通道（16）连通的分析物响应传感器（14）的传感器组件（12）。 该方法包括将传感器（14）暴露于参考样品，从而产生传感器响应。 该方法还允许对传感器（14）执行质量控制。 还提供了可以实施所要求保护的方法的装置（10）。

公开(公告)号：WO1996022051A1

公开(公告)日：1996-07-25

申请号：PCT/US1996000483

申请日：1996-01-05

Applicant: EVANS, Joseph, M.

IPC: A61B05/05

CPC classification number: A61B5/103 ,  A61B5/4504

Abstract: A method and apparatus allows for simple correction of resctricted spinal motion. The clinician applies a uniform low energy diagnostic impulse to each vertebral segment of interest (640) and the resulting force waveform is recorded. The force wavefroms of each diagnostic impulse are compared to determine the relative compliance of each vertebral segment. The clinician then selects the vertebral segment to be adjusted (655) on the basis of identification of fixated or hypo-mobile segments and high compliance or hyper-mobile segments. The last step may or may not include comparison of the post adjustment compliance of the spinal system under analysis (515) with the compliance before adjustments were performed on the spine.

Abstract translation: 一种方法和装置允许简单地校正脊柱运动。 临床医生对每个感兴趣的椎体段（640）应用均匀的低能量诊断脉冲，并记录所产生的力波形。 比较每个诊断脉冲的力波，以确定每个椎骨段的相对顺应性。 然后临床医生根据固定或低位移动段和高度依从性或超移动区段的识别来选择待调整的椎骨段（655）。 最后一步可能包括也可能不包括将脊柱系统分析（515）的后期调整顺应性与对脊柱进行调整之前的顺应性的比较。

公开(公告)号：WO1996017547A1

公开(公告)日：1996-06-13

申请号：PCT/US1995015172

申请日：1995-12-07

Applicant: BIOFIELD CORP.

Inventor： BIOFIELD CORP. ,  FAUPEL, Mark, L. ,  LONG, David, M., Jr.

IPC: A61B05/05

CPC classification number: A61B5/4312 ,  A61B5/04 ,  A61B5/04002 ,  A61B5/04085 ,  A61B5/05 ,  A61B5/0531 ,  A61B5/7264 ,  A61B5/7267 ,  A61B2562/0209 ,  A61B2562/046 ,  G06N3/0454 ,  Y10S706/924

Abstract: The present invention is a method and apparatus (10) for disease, injury or condition screening or sensing wherein bio-potentials are received from a plurality of measuring sensors (26a-d) located in the area of a suspected disease, injury or condition change site. These potentials are then processed by a processor (42), and the processed values are provided to a particular type of neural network (44) or a combination of neural networks uniquely adapted to receive and analyze data of an identifiable type to provide an indication (50) of specific conditions.

Abstract translation: 本发明是一种用于疾病，损伤或状况筛选或感测的方法和装置（10），其中从位于疑似疾病，损伤或状况变化区域的多个测量传感器（26a-d）接收生物电位 现场。 这些电位然后由处理器（42）处理，并且处理的值被提供给特定类型的神经网络（44）或神经网络的组合，其特别适于接收和分析可识别类型的数据以提供指示（ 50）具体条件。

公开(公告)号：WO1996001586A1

公开(公告)日：1996-01-25

申请号：PCT/US1995008856

申请日：1995-06-23

Applicant: REINING INTERNATIONAL LTD.

Inventor： REINING INTERNATIONAL LTD. ,  REINING, William, N.

IPC: A61B05/05

CPC classification number: A61B5/029 ,  A61B5/0295 ,  A61B5/0535

Abstract: An impedance cardiograph (10) which determines cardiac output from a measurement of variations of chest impedance (2), provides method of calculating the effect of patient volume on the measurement from measurable patient height (H) and chest circumference (C), and provides a correction process that identifies as a source of error variations in the first derivative of impedance. This latter source of error is minimized by preprocessing the impedance derivative value with a compression function which reduces the range of values of the impedance derivative when that value differs significantly from a norm of the population.

Abstract translation: 根据测量胸部阻抗变化（2）确定心输出量的阻抗心电图仪（10）提供了从可测量的患者身高（H）和胸围（C）计算患者体积对测量的影响的方法，并提供 校正过程，其识别阻抗的一阶导数中的误差源。 通过用压缩函数预处理阻抗导数值来最小化后一种误差源，当压缩导数值与群体规范明显不同时，减小阻抗导数的值的范围。

公开(公告)号：WO1995035060A1

公开(公告)日：1995-12-28

申请号：PCT/NZ1994000147

申请日：1994-12-20

Applicant: AUCKLAND UNISERVICES LIMITED ,  WILLIAMS, Christopher, Edward

Inventor： AUCKLAND UNISERVICES LIMITED

IPC: A61B05/05

CPC classification number: A61B5/0537 ,  A61B5/0535 ,  A61B5/4064 ,  A61B5/4094 ,  A61N1/05 ,  A61N1/08

Abstract: An impedance monitor (100) is adapted for use in long-term monitoring of intracellular (neuronal) swelling in the brains (102) of mammals over periods of hours or days. The monitor has an electrically isolated current source (103), supplying a one microampere AC square waveform at 200 Hz. This current is passed through an outer pair of electrodes (104, 105) of a four-electrode arrangement having skin electrodes, extradural electrodes, or in some cases surface electrodes embedded in surgical retractors. Sensing electrode pairs (107, 108) may also detect EEG activity. Impedance changes are displayed graphically (109). Multiple electrode arrays may be used for localisation of affected portions of the brain. Even trans-cranially measured impedances reflect intracellular oedema and are clinically useful indicators of treatment efficacy and outcome in cases of ischaemia, asphyxia, trauma, and the like.

Abstract translation: 阻抗监测器（100）适用于长时间监测哺乳动物的脑（102）中的细胞内（神经元）肿胀。 监视器具有电隔离电流源（103），以200Hz提供一个微安AC方波。 该电流通过具有皮肤电极，硬膜外电极或在某些情况下嵌入在手术牵开器中的表面电极的四电​​极装置的外部一对电极（104,105）。 感测电极对（107,108）也可以检测EEG活性。 阻抗变化以图形方式显示（109）。 可以使用多个电极阵列来定位受影响的脑部分。 甚至跨颅测量的阻抗反映细胞内水肿，并且在局部缺血，窒息，创伤等的情况下是治疗功效和结果的临床有用指标。

公开(公告)号：WO1995009562A1

公开(公告)日：1995-04-13

申请号：PCT/US1994011298

申请日：1994-10-06

Applicant: BIOSENSE, INC.

Inventor： BIOSENSE, INC. ,  ACKER, David, Ellis ,  MCNULTY, Ian ,  PACHECO, Robert, C. ,  GRANDNER, Wayne

IPC: A61B05/05

CPC classification number: A61B5/103 ,  A61B5/062 ,  A61B5/4528 ,  A61B34/20 ,  A61B90/361 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61B2562/0223 ,  G01R33/0206 ,  Y10T29/49004 ,  Y10T29/4902 ,  Y10T29/49075

Abstract: A magnetic position and orientation determining system uses magnetic fields, desirably comprising uniform fields from Helmholtz coils (34, 36, 38) positioned on opposite sides of a sensing volume and gradient fields generated by the same coils. By monitoring field components detected at the probes (50) during application of these fields, the position and orientation of the probe (50) in the field can be deduced. A representation (108) of the probe (50) can be superposed on a separately acquired image of the subject to show the position and orientation of the probe (50) with respect to the subject.

Abstract translation: 磁位置和取向确定系统使用磁场，期望地包括位于感测体积的相对侧上的亥姆霍兹线圈（34,36,38）的均匀场和由相同线圈产生的梯度场的磁场。 通过在施加这些场期间监测在探针（50）处检测到的场分量，可以推导出探头（50）在场中的位置和取向。 探针（50）的表示（108）可以叠加在被摄体的单独获取的图像上，以示出探针（50）相对于被摄体的位置和取向。

公开(公告)号：WO1994015529A1

公开(公告)日：1994-07-21

申请号：PCT/EP1994000019

申请日：1994-01-05

Applicant: ACADEMISCH ZIEKENHUIS UTRECHT ,  KONINGS, Maurits, Karel

Inventor： ACADEMISCH ZIEKENHUIS UTRECHT

IPC: A61B05/05

CPC classification number: A61B5/0537 ,  A61B5/02007 ,  A61B5/0538 ,  A61B5/4872

Abstract: Method of operating, catheter and catherization system for measuring electrical impedances in blood vessels within an annular area around the catheter. The catheter contains excitation electrodes (T1, T2 & S1, S2) between which the impedance is measured, the measurement being a potential difference between measuring electrodes (Me1, Me2, Me3) present between those excitation electrodes. The two pairs of excitation electrodes are electrically driven in opposition to set up a controllable pattern of electric field lines (a so-called "counter current field"). By varying the amplitudes of the two excitaton currents, the electric field can be adjusted such that: a) no (or hardly any) current flows between the measuring electrodes (the "quenching relation"), and b) at a distance away from the measuring electrodes the electric field lines are substantially perpendicular to the longitudinal axis of the catheter. The average impedance of the area-to-be-measured and that of the area outside of this given area can then be measured separately.

Abstract translation: 用于测量导管周围环形区域内血管电阻的操作方法，导管和引导系统。 该导管包含测量阻抗的激励电极（T1，T2和S1，S2），该测量是存在于这些激发电极之间的测量电极（Me1，Me2，Me3）之间的电位差。 两对激励电极相对电驱动以建立电场线的可控模式（所谓的“逆流场”）。 通过改变两个激发电流的幅度，可以调节电场，使得：a）在测量电极之间没有（或几乎不存在）电流流动（“淬灭关系”），以及b）在远离 测量电极，电场线基本上垂直于导管的纵向轴线。 然后可以单独测量待测区域的平均阻抗和该给定区域以外的区域的平均阻抗。

公开(公告)号：WO1993004628A1

公开(公告)日：1993-03-18

申请号：PCT/US1992007253

申请日：1992-08-27

Applicant: NAVION BIOMEDICAL CORPORATION

Inventor： NAVION BIOMEDICAL CORPORATION ,  SHAPIRO, Alan, R. ,  KAY, Donald, A. ,  STROHL, Clair, L., Jr.

IPC: A61B05/05

CPC classification number: G01V3/105 ,  A61B5/06 ,  A61B5/062 ,  A61B34/20 ,  A61B2034/107 ,  A61B2034/2051 ,  A61B2090/3958 ,  H01F2005/027

Abstract: A system for externally locating the depth and orientation of a catheter (9) in tissue with an external probe (12) which generates a virtual rotating magnetic field. The catheter (9) includes an inductive coil (30) for developing an induced signal in response to the virtual rotating magnetic field. An indicating device (6) such as a light bar display or digital readout indicates the strength of the induced signal for locating, independently of the relative angular orientation of the probe and the catheter, the depth in the tissue of the catheter.

Abstract translation: 一种用外部定位导管（9）在组织中的深度和取向的系统，该外部探针（12）产生虚拟的旋转磁场。 导管（9）包括用于响应于虚拟旋转磁场产生感应信号的感应线圈（30）。 诸如光条显示器或数字读出器的指示装置（6）独立于探针和导管的相对角度取向指示导尿管组织中的深度，指示用于定位的感应信号的强度。

公开(公告)号：WO1992019155A1

公开(公告)日：1992-11-12

申请号：PCT/RU1992000092

申请日：1992-04-24

Applicant: SARCHUK, Viktor Nikolaevich ,  KARPLJUK, Anatoly Andreevich ,  KOMAROV, Anatoly Semenovich ,  TULIEV, Valery Stepanovich

IPC: A61B05/05

CPC classification number: A61N1/36014 ,  A61B5/0532

Abstract: The invention relates to medical technique and in particular to a device for galvanopuncture diagnostics. The aim of the invention is to increase the reliability and to shorten the duration of the testing procedure. The aim is achieved due to the fact that a unit (12) of microresonance circuits consists of commutation cells connected to a control bus (14) intended for sending commands for grouped connection of these cells, whereas the output of the unit of microresonance circuits is connected to a unit (11) for cancelling the bioenergetic burdening of the patient, connected to an electric conductivity measuring unit (1).

Abstract translation: 本发明涉及医疗技术，特别涉及一种用于电穿刺诊断的装置。 本发明的目的是提高可靠性并缩短测试过程的持续时间。 目的是实现这样一个事实：微谐振电路的单元（12）由连接到控制总线（14）的换向单元组成，该控制总线（14）用于发送用于这些单元的分组连接的命令，而微谐振电路单元的输出为 连接到与电导率测量单元（1）连接的用于消除患者的生物能量负荷的单元（11）。

公开(公告)号：WO1992019154A1

公开(公告)日：1992-11-12

申请号：PCT/NL1991000071

申请日：1991-04-29

Applicant: LERNER, Inna ,  LERNER, Edward Naumovich

Inventor： LERNER, Inna

IPC: A61B05/05

CPC classification number: A61B5/4824 ,  A61B5/0531 ,  A61B5/1106 ,  A61B5/4011

Abstract: The invention provides a method and an instrument for measuring sensory functions (hearing vision, smell, tactile sense and pain sensitivity) of a human or an animal, whereby the sense under investigation is stimulated and the resulting change of a skin potential is recorded. Preferably, another stimulus such as an electric potential is applied, optionally several times with varying intervals and varying intensity, prior to the stimulation of the sense under investigation.

Abstract translation: 本发明提供了一种用于测量人或动物的感官功能（听觉，气味，触觉和疼痛敏感性）的方法和仪器，由此刺激了所研究的感觉并记录了所导致的皮肤电位变化。 优选地，在刺激所研究的感觉之前，施加诸如电势的另一个刺激，可选地几次以不同的间隔和变化的强度。