公开(公告)号：EP0471898A1

公开(公告)日：1992-02-26

申请号：EP90309180.9

申请日：1990-08-22

Applicant: NELLCOR INCORPORATED

Inventor： Chung, Christopher ,  McNamara, Helen

IPC: A61B5/00 ,  A61B5/0448

CPC classification number: A61B5/1464 ,  A61B5/1076 ,  A61B5/14542

Abstract: An intrauterine pulse oximetry apparatus and method are provided to measure foetal blood oxygen saturation at sites in a preferred region on the foetus. The sensor (103) of the apparatus (100) is attached to a stiff cable (102) which can be inserted into the uterus past the presenting part and transcervical region of the foetus. The cable may have visual and tactile markings (107, 108) by which the user, without seeing or feeling the sensor, can guide it to an appropriate site on the foetus.

Abstract translation: 提供宫内脉搏血氧饱和度测量装置和方法来测量胎儿优选区域中的胎儿血氧饱和度。 装置（100）的传感器（103）附接到刚性电缆（102），该刚性电缆可以插入到子宫中超过胎儿的呈现部分和子宫颈区域。 电缆可以具有视觉和触觉标记（107,108），通过该标记，用户不需要感觉到传感器就可以将其引导到胎儿上的适当位置。

公开(公告)号：EP0406334A4

公开(公告)日：1991-11-13

申请号：EP89908107

申请日：1989-07-10

Applicant: NELLCOR INCORPORATED

Inventor： BOESTERLING, BERNHARD, J. ,  CHANG, DANIEL, M. ,  MADONIK, ALEX, M. ,  STONE, ROBERT, T.

IPC: C08G18/08 ,  C08G18/38 ,  G01N31/22 ,  G01N33/52 ,  C08G18/32 ,  G01N21/78 ,  G01N33/50

CPC classification number: C08G18/38 ,  C08G18/0804 ,  C08G2210/00 ,  G01N31/221 ,  G01N33/526

Abstract: Reactive azo dyes, hydrogels, dye films (9) prepared therefrom, and sensing elements incorporating such films are disclosed. The sensing elements are useful, e.g., in body fluid analyzing devices, where they are capable of providing accurate information on the pH or pCO2 of fluids such as blood.

公开(公告)号：EP0289581A4

公开(公告)日：1990-12-12

申请号：EP87907697

申请日：1987-10-16

Applicant: NELLCOR INCORPORATED

Inventor： CORENMAN, JAMES, E. ,  GOLDBERGER, DANIEL, S. ,  BRAIG, JAMES, R. ,  ROJAS, EMIL, P. ,  RICHARDS, EDWARD, M. ,  GALLUP, DAVID, A.

IPC: A61B5/08 ,  A61B5/083 ,  G01N21/31 ,  G01N21/35 ,  G01N21/61 ,  G06F15/46 ,  G01N21/37

CPC classification number: A61B5/083 ,  G01N21/3504 ,  G01N21/61 ,  G01N2021/3129 ,  G01N2201/121

Abstract: An improved gas analyzer system and method for detecting and displaying the constituent gases of a respiratory gas stream, the system comprising an optical bench (109) comprising a gas pathway for the flow of a gas stream, a flow shaping inlet, three infrared detection channel assemblies for measuring the partial pressures of constituent gases, and measuring sensitivity changes in the detectors of the three infrared detection channel assemblies, a pressure sensor for measuring the pressure within the gas pathway, a temperature sensor for measuring the temperature within the optical bench, a flow rate sensor for measuring the gas flow rate through the gas pathway; analog processing circuitry (124) for processing the detected partial gas pressures, sensitivity changes, the measured values for pressure, temperature, and flow rate, and display processing circuitry (128).

公开(公告)号：EP0335356A3

公开(公告)日：1990-08-29

申请号：EP89105501.4

申请日：1989-03-29

Applicant: NELLCOR INCORPORATED

Inventor： Stone, Robert T. ,  Briggs, Deborah A.

IPC: A61B5/00

CPC classification number: A61B5/14551 ,  A61B5/7207

Abstract: A method and apparatus for improving the calculation of oxygen saturation by non-invasive pulse oximeters during transient conditions. Tran­sient conditions introduce artifactual errors into the detected optical signal because of changes in transmittance of the light with localized blood volume changes and as the average background oxygen saturation level of the patient's blood changes. The invention relates to correcting the detected optical pulses by selective frequency filtering and compensating the detected optical signal using the filtered signal to provide accurate estimates of oxygen saturation during transient conditions.

公开(公告)号：EP0217918B1

公开(公告)日：1990-05-30

申请号：EP86902611.2

申请日：1986-03-31

Applicant: NELLCOR INCORPORATED

Inventor： GOODMAN, David, E. ,  CORENMAN, James, E.

IPC: A61B5/00 ,  A61B5/02 ,  A61B5/04

CPC classification number: A61B5/14551 ,  A61B5/02416 ,  A61B5/0245 ,  A61B5/04282 ,  A61B5/7207

Abstract: A method and apparatus for measuring and correlating a patient's heart activity with optical detection of the patient's blood flow. The method and apparatus permit more accurate determination of blood flow characteristics such as oxygen saturation and pulse rate. In a preferred embodiment, the heart activity is detected by monitoring the patient's EKG waveform (100), and the blood flow is detected by a non-invasive pulse oximeter (200). The occurrence of the R wave portion of the EKG signal is detected and the time delay by which an arterial pulse follows the R wave is determined to establish a time window in which an arterial is to be expected. The established time window provides the oximeter (200) with a parameter enabling the oximeter (200) to analyze the blood flow only when it is likely to present an arterial blood pulse for waveform analysis. The invention also includes means for adjusting the polarity of the detected EKG signal (160) to obtain a preselected uniform upgoing or downgoing polarity.

公开(公告)号：EP0104771B1

公开(公告)日：1990-05-23

申请号：EP83304938.0

申请日：1983-08-25

Applicant: NELLCOR INCORPORATED

Inventor： New, William, Jr. ,  Corenman, James E.

IPC: A61B5/02 ,  A61B5/00 ,  G01N21/25

CPC classification number: A61B5/14551

公开(公告)号：EP0329196A3

公开(公告)日：1989-09-13

申请号：EP89105503.0

申请日：1983-08-25

Applicant: NELLCOR INCORPORATED

Inventor： New, William, Jr. ,  Corenman, James E.

IPC: A61B5/00

CPC classification number: A61B5/14552 ,  A61B5/1495 ,  A61B2562/08 ,  G01N21/3151 ,  G01N35/00732

Abstract: The oximeter for cooperation with an oximeter probe comprises decoding means responsive to encoded signals for selecting appropriate calibration coefficients for use in calculating oxygen saturation based upon the known wavelength of first and/or second light emitting means (10, 132 and 20, 130, resp.) in the probe. A probe comprises a pair of light emitting means preferably diodes (10, 20, 130, 132) which emit light of narrow wavebands having known characteristic wavelengths through part of a patient onto a photosensor (30, 38). A coding means comprising resistor (40) of coded known resistance or else an eight bit connector (52′) is used to enable the oximeter to calculate the coefficient of extinction of the wavelengths of the LEDs. The resistor, LEDs and photosensor are mounted on self-attaching hook and eye tape (50) for mounting the probe onto the appendage of the patient. The probe is detachably wired to the oximeter, rendering the probe completely disposable. The oximeter is programmed at the factory to calculate the co-efficients of extinction of any LEDS which may be encountered in a series of disposable probes. From the co-efficients of extinction, the pulse rate and degree of arterial oxygen saturation is computed and displayed by the oximeter.

公开(公告)号：EP0257916A1

公开(公告)日：1988-03-02

申请号：EP87307121.1

申请日：1987-08-12

Applicant: NELLCOR INCORPORATED

Inventor： Fehder, Carl G., Dr.

IPC: G01N31/22

CPC classification number: G01N31/223 ,  A61M2016/0413

Abstract: A rapid response device for the detection of carbon dioxide in a concentration of more than 2% in a gas mixture comprising an indicator component 9 mounted within an enclosure 1 with a transparent window, said component comprising a carrier having fixedly attached thereto an indicating element formed from an aqueous solution of a colorless base, a hygroscopic, high boiling, transparent, colorless, water-­miscible liquid and a pH-sensitive indicator, the enclosure being sealed for storage with sealing means 14.

Abstract translation: 一种用于在包括安装在具有透明窗口的外壳1内的指示器部件9的气体混合物中检测浓度超过2％的二氧化碳的快速响应装置，所述部件包括固定地附接到其上的指示元件，所述指示元件形成 从无色碱的水溶液，吸湿性，高沸点，透明，无色的水混溶性液体和pH敏感指示剂中，封装密封以用密封装置14存储。

公开(公告)号：EP0217918A1

公开(公告)日：1987-04-15

申请号：EP86902611.0

申请日：1986-03-31

Applicant: NELLCOR INCORPORATED

Inventor： GOODMAN, David, E. ,  CORENMAN, James, E.

IPC: A61B5

CPC classification number: A61B5/14551 ,  A61B5/02416 ,  A61B5/0245 ,  A61B5/04282 ,  A61B5/7207

Abstract: Une méthode et un appareil pour mesurer et mettre en corrélation avec la détection optique du débit sanguin d'un patient l'activité cardiaque du patient. La méthode et l'appareil permettent de déterminer avec plus de précision les caractéristiques du débit sanguin telles que la saturation en oxygène et la vitesse du pouls. Dans une version préférée, l'activité cardiaque est détectée en surveillant la forme de l'onde EKG du patient, et le débit sanguin est détecté par un oxygénomètre à pulsations non invasif. L'apparition de la partie d'onde R du signal EKG est détectée et l'écart temporel entre une pulsation artérielle et l'onde R est déterminé pour établir une période de temps pendant laquelle une pulsation artérielle doit être attendue. La période de temps calculé fournit à l'oxygénomètre un paramètre lui permettant d'analyser le débit sanguin seulement lorsqu'il est susceptible de présenter une pulsation de sang artériel pour l'analyse de la forme de l'onde. L'invention comprend aussi le réglage de la polarité du signal EKG détecté pour avoir une polarité montante ou descendante uniforme présélectionnée.

公开(公告)号：EP0127947A3

公开(公告)日：1986-07-30

申请号：EP84302994

申请日：1984-05-03

Applicant: NELLCOR INCORPORATED

Inventor： Corenman, James E. ,  New, William, Jr. ,  Yelderman, Mark ,  Goodman, David E.

IPC: A61B05/02

CPC classification number: A61B5/6819 ,  A61B5/02427 ,  A61B5/14552 ,  A61B5/6826 ,  A61B5/6838

Abstract: A sensor for trans-illumination of a blood perfused portion of flesh to measure light extinction during trans- illumination is disclosed. The sensor is preferably mounted on a fingertip but any digit or blood perfused portion of flesh will work. The sensor includes a first end for disposition on one side of the trans-illuminated flesh and a second end for disposition on the opposite and opposed side of the trans- illuminated flesh. A light source is mounted to the first side and a photo- sensor is mounted to the second side. If an elongated flexible strip is used, it is provided with adhesive and is suitably windowed that light is allowed to take an optical path through the finger. If no flexible strip is used, the two ends are aligned and secured to the flesh such that the light emitted takes an optical path through the finger. When the adhesive fastener is used, the effect of the light source and photo-detector substrates being integrated into the adhesive fastener is that they become, in effect, a part of the skin. The resulting device is resistant to accidental removal and avoids constriction of blood vessels. Most importantly, the low mass of the sensor itself and its conformance to, so as to effectively become a part of, the skin, prevents relative motion between the light source and sensor and the perfused flesh. This eliminates the common interference associated with the operation of conventional plethysmographs and oximeters.