公开(公告)号：EP0551142A3

公开(公告)日：1994-07-20

申请号：EP93101050.8

申请日：1987-10-16

Applicant: NELLCOR INCORPORATED

Inventor： Corenman, James E. ,  Goldberger, Daniel S. ,  Braig, James R. ,  Rojas, Emil P. ,  Richards, Edward M. ,  Gallup, David A.

IPC: G01N1/24 ,  A61B5/08 ,  B01D46/04 ,  G01N21/35 ,  A61B5/097 ,  A61M16/08 ,  G01N33/497

CPC classification number: A61B5/083 ,  G01N21/3504 ,  G01N21/61 ,  G01N2021/3129 ,  G01N2201/121

Abstract: An improved gas analyzer system and method for detecting and displaying the constituent gases of a respiratory gas stream, the system comprising an optical bench (109) comprising a gas pathway for the flow of a gas stream, a flow shaping inlet, three infrared detection channel assemblies for measuring the partial pressures of constituent gases, and measuring sensitivity changes in the detectors of the three infrared detection channel assemblies, a pressure sensor for measuring the pressure within the gas pathway, a temperature sensor for measuring the temperature within the optical bench, a flow rate sensor for measuring the gas flow rate through the gas pathway; analog processing circuitry (124) for processing the detected partial gas pressures, sensitivity changes, the measured values for pressure, temperature, and flow rate, and display processing circuitry (128).

公开(公告)号：EP0102816A3

公开(公告)日：1985-08-28

申请号：EP83304939

申请日：1983-08-25

Applicant: NELLCOR INCORPORATED

Inventor： New, William, Jr. ,  Corenman, James E.

IPC: A61B05/02 ,  A61B05/00 ,  G01N21/25

CPC classification number: A61B5/14551 ,  A61B5/02416 ,  G01N21/3151

Abstract: @ A pulse oximeter is disclosed of the type wherein light of two different wavelengths is passed through human or animal body tissue, such as a finger, an ear, the nasal septum or the scalp, so as to be modulated by the pulsatile component of arterial blood therein, and thereby allowing indication of oxygen saturation. The level of incident light is continually adjusted for optimal detection of the pulsatile component, while permitting accommodation to variable attenuations due to skin color, flesh thickness and other invariants. At significant slope reversal of the pulsatile component to negative (indicating a wave maximum), wave form analysis of blood flow occurs. A quotient of the pulsatile component of light transmission over the constant component of light transmission is measured for each of two wave lengths by direct digital tracking. The respective quotients are thereafter converted to a ratio, which ratio may be thereafter fitted to a curve of independently derived of oxygen saturation. Calibration is disclosed by solving four unknowns at at least four differing saturations. An output of pulse rate, pulse flow and oxygen saturation is given. An incident light source duty cycle is chosen to be at least 1 in 4 so that noise, inevitably present in the signal, may be substantially eliminated and filtered. Provision is made for a local battery-driven low power consumption instrument capable of being substantially independent of ambient light noise.

Abstract translation: 公开了一种脉冲血氧计，其中两种不同波长的光通过诸如手指，耳朵，鼻中隔或头皮的人或动物体组织，以便被动脉血的脉动成分调制 从而允许氧饱和度的指示。 连续调整入射光的水平，以最佳地检测脉动分量，同时允许由于皮肤颜色，肉体厚度和其他不变量而调节可变衰减。 在显着斜率将脉动分量反转为负（表示波最大值）时，发生血流波形分析。 通过直接数字跟踪测量光传输的恒定分量上的光透射的脉动分量的商为两个波长中的每一个。 然后将各商商转换成一个比例，该比率之后可以适应于独立地衍生氧饱和度的曲线。 通过在至少四个不同饱和度下解决四个未知数来公开校准。 给出了脉搏率，脉冲流量和氧饱和度的输出。 选择入射光源占空比至少为1/4，使得不可避免地存在于信号中的噪声基本上可以被消除和滤波。 规定了本地电池驱动的低功耗仪器，其能够基本上独立于环境光噪声。

公开(公告)号：EP0104771A3

公开(公告)日：1985-08-28

申请号：EP83304938

申请日：1983-08-25

Applicant: NELLCOR INCORPORATED

Inventor： New, William, Jr. ,  Corenman, James E.

IPC: A61B05/02 ,  A61B05/00 ,  G01N21/25

CPC classification number: A61B5/14551

Abstract: A pulse oximeter wherein light of two different wavelengths is passed through body tissue, such as a finger, an ear or the scalp, so as to be modulated by the pulsatile component of arterial blood therein and thereby indicate oxygen saturation. A tonal signal is emitted having a pitch proportional to the ratio of oxygen saturation and a sequential repetition proportional to pulse. A visual cue consisting of an array of strobed light emitting diodes is flashed having a total light output proportional to the magnitude of the pulse and a sequential flashing rate proportional to pulse rate. A systematic rejection of extraneous or irregular detected data prevents undue sounding of alarms.

公开(公告)号：EP0135840A2

公开(公告)日：1985-04-03

申请号：EP84110306.2

申请日：1984-08-29

Applicant: NELLCOR INCORPORATED

Inventor： Corenman, James E. ,  New, William, Jr. ,  Goodman, David E. ,  Yelderman, Mark

IPC: A61B5/00 ,  A61B5/04 ,  G01N21/27

CPC classification number: A61B5/1464 ,  A61B5/04485 ,  A61B5/14542 ,  A61B5/4362 ,  A61B5/6834

Abstract: An intravaginal and intrauterine sensor for transillumination of a blood-perfused portion of fetal tissue to measure light extinction. The sensor comprises at least one light source (21, 23) and at least one photo-sensor (20, 22) with a shielding (30). The sensor may be mounted onto a paddle-shaped probe provided with signal connections (25, 26) contained in an insulated cable (27) leading to a measurement device. Alternatively, the sensor may include an opaque suction cup or other attaching apparatus for disposition on a protruding portion of the fetus. Most preferably, the sensor includes a housing.

Abstract translation: 用于透射胎儿组织血液灌注部分以测量光灭绝的阴道内和子宫内传感器。 传感器包括至少一个光源（21,23）和至少一个具有屏蔽（30）的光传感器（20,22）。 传感器可以安装在具有包含在通向测量装置的绝缘电缆（27）中的信号连接（25,26）的桨状探针上。 或者，传感器可以包括不透明的吸盘或用于配置在胎儿的突出部分上的其它附接装置。 最优选地，传感器包括壳体。

公开(公告)号：EP0335357B1

公开(公告)日：1996-05-08

申请号：EP89105502.2

申请日：1989-03-29

Applicant: NELLCOR INCORPORATED

Inventor： Goodman, David E. ,  Briggs, Deborah A. ,  Boross, Andras ,  Corenman, James E. ,  Stone, Robert T.

IPC: A61B5/00

CPC classification number: A61B5/14551 ,  A61B5/02416 ,  A61B5/0245 ,  A61B5/04282 ,  A61B5/7207 ,  A61B5/7225 ,  A61B5/7257

公开(公告)号：EP0104771B1

公开(公告)日：1990-05-23

申请号：EP83304938.0

申请日：1983-08-25

Applicant: NELLCOR INCORPORATED

Inventor： New, William, Jr. ,  Corenman, James E.

IPC: A61B5/02 ,  A61B5/00 ,  G01N21/25

CPC classification number: A61B5/14551

公开(公告)号：EP0329196A3

公开(公告)日：1989-09-13

申请号：EP89105503.0

申请日：1983-08-25

Applicant: NELLCOR INCORPORATED

Inventor： New, William, Jr. ,  Corenman, James E.

IPC: A61B5/00

CPC classification number: A61B5/14552 ,  A61B5/1495 ,  A61B2562/08 ,  G01N21/3151 ,  G01N35/00732

Abstract: The oximeter for cooperation with an oximeter probe comprises decoding means responsive to encoded signals for selecting appropriate calibration coefficients for use in calculating oxygen saturation based upon the known wavelength of first and/or second light emitting means (10, 132 and 20, 130, resp.) in the probe. A probe comprises a pair of light emitting means preferably diodes (10, 20, 130, 132) which emit light of narrow wavebands having known characteristic wavelengths through part of a patient onto a photosensor (30, 38). A coding means comprising resistor (40) of coded known resistance or else an eight bit connector (52′) is used to enable the oximeter to calculate the coefficient of extinction of the wavelengths of the LEDs. The resistor, LEDs and photosensor are mounted on self-attaching hook and eye tape (50) for mounting the probe onto the appendage of the patient. The probe is detachably wired to the oximeter, rendering the probe completely disposable. The oximeter is programmed at the factory to calculate the co-efficients of extinction of any LEDS which may be encountered in a series of disposable probes. From the co-efficients of extinction, the pulse rate and degree of arterial oxygen saturation is computed and displayed by the oximeter.

公开(公告)号：EP0127947A3

公开(公告)日：1986-07-30

申请号：EP84302994

申请日：1984-05-03

Applicant: NELLCOR INCORPORATED

Inventor： Corenman, James E. ,  New, William, Jr. ,  Yelderman, Mark ,  Goodman, David E.

IPC: A61B05/02

CPC classification number: A61B5/6819 ,  A61B5/02427 ,  A61B5/14552 ,  A61B5/6826 ,  A61B5/6838

Abstract: A sensor for trans-illumination of a blood perfused portion of flesh to measure light extinction during trans- illumination is disclosed. The sensor is preferably mounted on a fingertip but any digit or blood perfused portion of flesh will work. The sensor includes a first end for disposition on one side of the trans-illuminated flesh and a second end for disposition on the opposite and opposed side of the trans- illuminated flesh. A light source is mounted to the first side and a photo- sensor is mounted to the second side. If an elongated flexible strip is used, it is provided with adhesive and is suitably windowed that light is allowed to take an optical path through the finger. If no flexible strip is used, the two ends are aligned and secured to the flesh such that the light emitted takes an optical path through the finger. When the adhesive fastener is used, the effect of the light source and photo-detector substrates being integrated into the adhesive fastener is that they become, in effect, a part of the skin. The resulting device is resistant to accidental removal and avoids constriction of blood vessels. Most importantly, the low mass of the sensor itself and its conformance to, so as to effectively become a part of, the skin, prevents relative motion between the light source and sensor and the perfused flesh. This eliminates the common interference associated with the operation of conventional plethysmographs and oximeters.

公开(公告)号：EP0104771A2

公开(公告)日：1984-04-04

申请号：EP83304938.0

申请日：1983-08-25

Applicant: NELLCOR INCORPORATED

Inventor： New, William, Jr. ,  Corenman, James E.

IPC: A61B5/02 ,  A61B5/00 ,  G01N21/25

CPC classification number: A61B5/14551

Abstract: A pulse oximeter wherein light of two different wavelengths is passed through body tissue, such as a finger, an ear or the scalp, so as to be modulated by the pulsatile component of arterial blood therein and thereby indicate oxygen saturation. A tonal signal is emitted having a pitch proportional to the ratio of oxygen saturation and a sequential repetition proportional to pulse. A visual cue consisting of an array of strobed light emitting diodes is flashed having a total light output proportional to the magnitude of the pulse and a sequential flashing rate proportional to pulse rate. A systematic rejection of extraneous or irregular detected data prevents undue sounding of alarms.

Abstract translation: 一种脉冲血氧计，其中两个不同波长的光通过诸如手指，耳朵或头皮的身体组织，以便由其中的动脉血的脉动分量调节，从而指示氧饱和度。 发出音调信号，其音调与氧饱和度的比例和与脉冲成比例的顺序重复比例。 一组由选通的发光二极管组成的视觉提示被闪烁，其具有与脉冲幅度成比例的总光输出和与脉率成比例的顺序闪烁速率。 系统地拒绝外部或不正确的检测数据可以防止警报的不适当的声音。

公开(公告)号：EP0551924A2

公开(公告)日：1993-07-21

申请号：EP93101101.9

申请日：1987-10-16

Applicant: NELLCOR INCORPORATED

Inventor： Corenman, James E. ,  Goldberger, Daniel S. ,  Braig, James R. ,  Rojas, Emil P. ,  Richards, Edward M. ,  Gallup, David A.

IPC: A61B5/08 ,  G09G5/36 ,  G01N21/35 ,  G01R13/30 ,  G06F15/20 ,  G06F15/42

CPC classification number: A61B5/083 ,  G01N21/3504 ,  G01N21/61 ,  G01N2021/3129 ,  G01N2201/121

Abstract: An improved gas analyzer system and method for detecting and displaying the constituent gases of a respiratory gas stream, the system comprising an optical bench (109) comprising a gas pathway for the flow of a gas stream, a flow shaping inlet, three infrared detection channel assemblies for measuring the partial pressures of constituent gases, and measuring sensitivity changes in the detectors of the three infrared detection channel assemblies, a pressure sensor for measuring the pressure within the gas pathway, a temperature sensor for measuring the temperature within the optical bench, a flow rate sensor for measuring the gas flow rate through the gas pathway; analog processing circuitry (124) for processing the detected partial gas pressures, sensitivity changes, the measured values for pressure, temperature, and flow rate, and display processing circuitry (128).

Abstract translation: 一种用于检测和显示呼吸气流的构成气体的改进的气体分析器系统和方法，该系统包括光学台（109），其包括用于气流流动的气体通路，流动成形入口，三个红外检测通道 用于测量构成气体的分压的组件，以及测量三个红外检测通道组件的检测器中的灵敏度变化，用于测量气体通道内的压力的压力传感器，用于测量光学平台内的温度的温度传感器， 用于测量通过气体通道的气体流量的流量传感器; 模拟处理电路（124），用于处理检测到的部分气体压力，灵敏度变化，压力，温度和流量的测量值以及显示处理电路（128）。