公开(公告)号：WO2007076444A3

公开(公告)日：2007-07-05

申请号：PCT/US2006/062499

申请日：2006-12-21

Applicant: COLGATE-PALMOLIVE COMPANY ,  PRENCIPE, Michael ,  FRUGE, Linh ,  MELLO, Sarita, V. ,  GAFFAR, Abdul

Inventor： PRENCIPE, Michael ,  FRUGE, Linh ,  MELLO, Sarita, V. ,  GAFFAR, Abdul

IPC: A61K8/27 ,  A61K8/365 ,  A61Q11/00 ,  A61K31/194 ,  A61K33/30

Abstract: Methods and oral compositions for reducing one or more of plaque, tartar/ caries, dentinal sensitivity, malodor, and/ or inflammation are provided. The composition comprise an active ingredient that comprises a zinc salt.

公开(公告)号：WO2007002887A1

公开(公告)日：2007-01-04

申请号：PCT/US2006/025521

申请日：2006-06-28

Applicant: COLGATE-PALMOLIVE COMPANY ,  MAITRA, Prithwiraj ,  CHOPRA, Suman, K. ,  IBRAHIM, Sayed ,  PASHKOVSKI, Eugene ,  PRENCIPE, Michael

Inventor： MAITRA, Prithwiraj ,  CHOPRA, Suman, K. ,  IBRAHIM, Sayed ,  PASHKOVSKI, Eugene ,  PRENCIPE, Michael

IPC: A61K8/24 ,  A61K8/81 ,  A61Q11/00

CPC classification number: A61K8/19 ,  A61K8/24 ,  A61K8/26 ,  A61K8/29 ,  A61K8/8111 ,  A61K8/8123 ,  A61K8/8152 ,  A61Q11/00

Abstract: Compositions for altering the color of teeth, including tooth-coating compositions comprising a colorant and an acrylate polymer. Colorants among those useful herein include whiteness-imparting particulate materials, such as hydroxyapatite.

Abstract translation: 用于改变牙齿颜色的组合物，包括包含着色剂和丙烯酸酯聚合物的牙齿涂料组合物。 可用于本文的着色剂包括赋予白度的颗粒材料，例如羟基磷灰石。

公开(公告)号：WO2006073822A1

公开(公告)日：2006-07-13

申请号：PCT/US2005/046240

申请日：2005-12-21

Applicant: COLGATE-PALMOLIVE COMPANY ,  SHASTRY, Ramachandra ,  MIRAJKAR, Yelloji, Rao ,  DIXIT, Nagaraj ,  CAMERON, Ryan ,  WANG, Qin ,  ZAIDEL, Lynette ,  CHOPRA, Suman, K. ,  PRENCIPE, Michael

Inventor： SHASTRY, Ramachandra ,  MIRAJKAR, Yelloji, Rao ,  DIXIT, Nagaraj ,  CAMERON, Ryan ,  WANG, Qin ,  ZAIDEL, Lynette ,  CHOPRA, Suman, K. ,  PRENCIPE, Michael

IPC: A61Q11/02 ,  A61K8/22 ,  A61K8/81

CPC classification number: A61K8/22 ,  A61K8/8152 ,  A61Q11/00

Abstract: In various embodiments, the present invention provides a tooth whitening composition comprising a peroxide composite and an orally acceptable carrier. The peroxide composite comprises a peroxide compound and a porous cross-linked polymer, preferably in the form of a microporous particulate. The peroxide compound can be sorbed onto the porous crosslinked polymer. The porous cross-linked polymer may comprise a polymerized polyunsaturated monomer selected from polyacrylates, polymethacrylates, polyitaconates, and mixtures thereof. The carrier can be non-aqueous, and can comprise a film forming material. Methods are also provided for whitening a tooth surface with the tooth whitening compositions.

Abstract translation: 在各种实施方案中，本发明提供了包含过氧化物复合物和口服可接受的载体的牙齿增白组合物。 过氧化物复合物包括过氧化物化合物和多孔交联聚合物，优选为微孔颗粒形式。 过氧化物可以吸附到多孔交联聚合物上。 多孔交联聚合物可以包含选自聚丙烯酸酯，聚甲基丙烯酸酯，多衣康酸酯及其混合物的聚合的多不饱和单体。 载体可以是非水的，并且可以包含成膜材料。 还提供了用于使牙齿美白组合物使牙齿美白的方法。

公开(公告)号：WO2006071677A2

公开(公告)日：2006-07-06

申请号：PCT/US2005/046370

申请日：2005-12-21

Applicant: COLGATE-PALMOLIVE COMPANY ,  IBRAHIM, Sayed ,  PATEL, Suryakant ,  CHOPRA, Suman, K. ,  PRENCIPE, Michael

Inventor： IBRAHIM, Sayed ,  PATEL, Suryakant ,  CHOPRA, Suman, K. ,  PRENCIPE, Michael

IPC: A61K8/24 ,  A61K8/89 ,  A61Q11/00

CPC classification number: A61K8/898 ,  A61K8/24 ,  A61Q11/00

Abstract: A tooth whitening composition for imparting a natural white appearance to dental enamel, comprising: a whitening particulate comprising hydroxyapatite and a delivery system comprising a silicone resin and a silicone adhesive. Methods of imparting whiteness to a tooth in a mammal are also provided.

Abstract translation: 一种赋予牙釉质天然白色外观的牙齿增白组合物，包括：包含羟基磷灰石的增白颗粒和包含有机硅树脂和硅氧烷粘合剂的递送系统。 还提供了赋予哺乳动物的牙齿白度的方法。

公开(公告)号：WO2005110343A1

公开(公告)日：2005-11-24

申请号：PCT/US2005/016146

申请日：2005-05-10

Applicant: COLGATE-PALMOLIVE COMPANY ,  IBRAHIM, Sayed ,  MAITRA, Prithwiraj ,  CHOPRA, Suman, K. ,  PASHKOVSKI, Eugene ,  PRENCIPE, Michael

Inventor： IBRAHIM, Sayed ,  MAITRA, Prithwiraj ,  CHOPRA, Suman, K. ,  PASHKOVSKI, Eugene ,  PRENCIPE, Michael

IPC: A61K7/16

CPC classification number: A61K8/24 ,  A61K8/29 ,  A61K8/894 ,  A61K2800/412 ,  A61K2800/43 ,  A61Q11/00

Abstract: Tooth-imparting whiteness to fluids comprising a particulate whiteness-imparting particles such as hydroxyapatite and an organosiloxane polymer are disclosed. Methods of use of the fluids are also disclosed.

Abstract translation: 公开了赋予包含颗粒状白度赋予颗粒如羟基磷灰石和有机硅氧烷聚合物的流体的白度。 还公开了使用流体的方法。

公开(公告)号：WO2005018593A2

公开(公告)日：2005-03-03

申请号：PCT/US2004/026413

申请日：2004-08-13

Applicant: COLGATE-PALMOLIVE COMPANY ,  CHOPRA, Suman, K. ,  ZAIDEL, Lynette, A. ,  PAN, Guisheng ,  PATEL, Suryakant ,  CAMERON, Ryan, B. ,  PRENCIPE, Michael

Inventor： CHOPRA, Suman, K. ,  ZAIDEL, Lynette, A. ,  PAN, Guisheng ,  PATEL, Suryakant ,  CAMERON, Ryan, B. ,  PRENCIPE, Michael

IPC: A61K7/20

CPC classification number: A61Q11/00 ,  A61C19/066 ,  A61K8/22 ,  A61K8/8111 ,  A61K8/8176 ,  A61K8/891

Abstract: A tooth whitening system comprising a tooth whitening composition comprising a whitening agent and a hydrophobic polymer carrier. The tooth whitening composition is preferably substantially non-water soluble. The tooth whitening composition is applied to the surface of a tooth to be whitened in a mammal to effect whitening on the tooth surface. Methods of whitening a surface of a tooth are also provided.

Abstract translation: 牙齿增白系统，其包含包含增白剂和疏水性聚合物载体的牙齿增白组合物。 牙齿增白组合物优选基本上不溶于水。 将该牙齿增白组合物施用于哺乳动物中待增白的牙齿的表面，以在牙齿表面上发白。 还提供了美白牙齿表面的方法。

公开(公告)号：WO2005016299A1

公开(公告)日：2005-02-24

申请号：PCT/US2004/026426

申请日：2004-08-13

Applicant: COLGATE-PALMOLIVE COMPANY ,  CHOPRA, Suman, K. ,  ZAIDEL, Lynette, A. ,  PAN, Guisheng ,  PATEL, Suryakant ,  CAMERON, Ryan, B. ,  PRENCIPE, Michael ,  COLLINS, Michael

Inventor： CHOPRA, Suman, K. ,  ZAIDEL, Lynette, A. ,  PAN, Guisheng ,  PATEL, Suryakant ,  CAMERON, Ryan, B. ,  PRENCIPE, Michael ,  COLLINS, Michael

IPC: A61K7/20

CPC classification number: A61K8/89 ,  A61C19/066 ,  A61K8/22 ,  A61K8/8176 ,  A61K8/891 ,  A61K8/895 ,  A61Q11/00

Abstract: A tooth whitening system comprising a dental tray having a surface operable to confront a tooth surface, and a tooth whitening composition comprising a whitening agent and a hydrophobic polymer carrier. The tooth whitening composition is preferably substantially non-water soluble. A tooth whitening kit is also provided using a dental tray and the tooth whitening composition comprising a whitening composition and a hydrophobic polymer carrier.

Abstract translation: 一种牙齿美白系统，其包括具有可操作以面对牙齿表面的表面的牙托盘，和包含增白剂和疏水性聚合物载体的牙齿增白组合物。 牙齿美白组合物优选基本上是非水溶性的。 还使用牙科托盘和含有美白组合物和疏水性聚合物载体的牙齿增白组合物来提供牙齿美白试剂盒。

公开(公告)号：WO2005000253A1

公开(公告)日：2005-01-06

申请号：PCT/US2004/020033

申请日：2004-06-23

Applicant: COLGATE-PALMOLIVE COMPANY ,  PRENCIPE, Michael ,  BOYD, Thomas, J. ,  CARALE, M., Teresa, R.

Inventor： PRENCIPE, Michael ,  BOYD, Thomas, J. ,  CARALE, M., Teresa, R.

IPC: A61K7/00

CPC classification number: A61Q11/00 ,  A61K8/25 ,  A61K8/44 ,  A61K8/4926 ,  A61K8/922

Abstract: A cationic-compatible inorganic particulate comprising silica substantially coated with a non-ionic surfactant, such as an ethoxylated hydrogenated hydrocarbon oil. Compositions comprising the cationic-compatible particulate and a cationic active, such as cetyl pyridinium chloride or an ethyl lauryl arginine ester, are also provided.

Abstract translation: 包含基本上涂覆有非离子表面活性剂如乙氧基化氢化烃油的二氧化硅的阳离子相容的无机颗粒。 还提供了包含阳离子相容性颗粒和阳离子活性物质的组合物，例如十六烷基氯化吡啶鎓或乙基月桂基精氨酸酯。

公开(公告)号：WO2014003776A1

公开(公告)日：2014-01-03

申请号：PCT/US2012/044832

申请日：2012-06-29

Applicant: COLGATE-PALMOLIVE COMPANY ,  MELLO, Sarita ,  PRENCIPE, Michael ,  FISHER, Steve ,  LAMBERT, Pierre ,  DELVENNE, Jean-Paul ,  VOGT, Robert

Inventor： MELLO, Sarita ,  PRENCIPE, Michael ,  FISHER, Steve ,  LAMBERT, Pierre ,  DELVENNE, Jean-Paul ,  VOGT, Robert

IPC: A61K8/25 ,  A61K8/73 ,  A61Q11/00

CPC classification number: A61K8/731 ,  A61K8/25 ,  A61Q11/00

Abstract: The invention provides high water content dentifrice compositions comprising a silica abrasive and a component containing microcrystalline cellulose and carboxymethylcellulose, as well as methods of making and using the same.

Abstract translation: 本发明提供了包含二氧化硅磨料和含有微晶纤维素和羧甲基纤维素的组分的高含水量洁牙剂组合物，以及制备和使用它们的方法。

公开(公告)号：WO2013089760A1

公开(公告)日：2013-06-20

申请号：PCT/US2011/065309

申请日：2011-12-16

Applicant: COLGATE-PALMOLIVE COMPANY ,  SZEWCZYK, Gregory ,  PATEL, Neeta Atul ,  JOGUN, Suzanne ,  PRENCIPE, Michael

Inventor： SZEWCZYK, Gregory ,  PATEL, Neeta Atul ,  JOGUN, Suzanne ,  PRENCIPE, Michael

IPC: A61K8/34 ,  A61K8/49 ,  A61K8/73 ,  A61Q11/00 ,  A61K8/02

CPC classification number: A61K49/00 ,  A61K8/0204 ,  A61K8/0233 ,  A61K8/345 ,  A61K8/4993 ,  A61K8/731 ,  A61K8/732 ,  A61K2800/43 ,  A61Q11/00 ,  B65D35/00

Abstract: Described herein are dentifrices comprising a first formulation and a second formulation, wherein the formulations are coaxially extruded, so that the first formulation enrobes the second formulation, wherein the first formulation is opaque and wherein the second formulation comprises dissolvable film fragments, together with methods of making and using the same and containers for providing the same.

Abstract translation: 本文描述的是包含第一制剂和第二制剂的洁齿剂，其中所述制剂被同轴挤出，使得第一制剂对第二制剂进行了刺激，其中第一制剂是不透明的，其中第二制剂包含可溶性膜片段， 使用和使用相同的容器提供相同的容器。