Abstract:
The present invention relates to novel compounds of Formula (I), their pharmaceutically acceptable derivatives, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of Formula (I), their pharmaceutically acceptable derivatives, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising novel compounds of Formula (I) and methods of treating or preventing one or more conditions or diseases that may be regulated or normalized via inhibition of Sodium Glucose Cotransporter-2 (SGLT-2).
Abstract:
The present invention provides a method and apparatus for handling in-device co-existence interference in user equipment. In one embodiment, a long term evolution (LTE)activity scheduled to be performed during an inactive time period of a LTE module in user equipment is determined. It is determined whether the LTE module is to be allowed to perform the LTE activity during the inactive time period. If the LTE activity is to be allowed, then the LTE module is allowed to perform the LTE activity during the inactive time period. Otherwise, the LTE module is not allowed to perform the LTE activity during the inactive time period to provide interference free time for an ISM module in the user equipment. Moreover, the disallowed LTE activity is scheduled to be performed during an active time period following the inactive time period.
Abstract:
The present invention provides a method and apparatus for handling in-device coexistence interference in user equipment. In one embodiment, a method includes receiving a list of non-serving LTE frequencies from a base station. The method includes configuring the non-serving LTE frequencies for performing measurements on the configured non-serving LTE frequencies. The method also includes detecting likelihood of in-device coexistence interference between at least one of the non-serving LTE frequencies and an ISM frequency when an ISM activity is ongoing on the ISM frequency.
Abstract:
The present invention provides methods and apparatusfor activating and deactivating secondary cells in a carrier aggregation environment. In one embodiment, a medium access control (MAC) control element (CE) command is received from a base station for activating/deactivating a secondary cell associated with user equipment (UE). Then, the secondary cell configured for user equipment is activated/deactivated based on the MAC CE command. Further, a first uplink grant is received from the base station upon activation/deactivation of the secondary cell. Accordingly, quality information (e.g., channel quality information and sounding reference signal information) associated with the cell(s) is transmitted to the base station in the received first uplink grant over a physical uplink shared channel. Furthermore, a hybrid automatic repeat request entity associated with the secondary cell is reset.
Abstract:
The present invention relates to novel compounds of Formula (I), their pharmaceutically acceptable derivatives, analogs, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of Formula I, their pharmaceutically acceptable derivatives, analogs, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising novel compounds of Formula I and methods of treating or preventing one or more conditions or diseases that may be regulated or normalized via inhibition of Sodium Glucose Cotransporter-2 (SGLT-2). The invention also relates to the use of compounds of Formula I, their pharmaceutically acceptable derivatives, analogs, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof, for the manufacture of a medicament for the prophylaxis, amelioration and/or treatment of conditions or diseases that may be regulated or normalized via inhibition of Sodium Glucose Cotransporter-2 (SGLT-2) and the related diseases, disorders and conditions, in a subject in need thereof.
Abstract:
Power system and method for providing electrical power are provided. The system includes a traction system and auxiliary equipment coupled to a power bus. The traction system includes one or more electromotive machines having a first type of stator winding that provides protection relative to voltage spikes expected at the traction stator under a first voltage level appropriate for the traction system. The auxiliary equipment includes one or more electromotive machines having a second type of stator winding that provides protection relative to spikes expected at the auxiliary stator under a second voltage level lower than the first voltage level. Inverter circuitry is coupled to drive the auxiliary equipment, and signal-conditioning circuitry is provided to attenuate voltage spikes produced by the inverter circuitry. The power bus is operated at the first voltage level, and the voltage spike attenuation is sufficient to protect the auxiliary stator.
Abstract:
The present invention relates to a compound of formula (I) or its stereoisomers, tautomers, solvates, hydrates, prodrugs, pharmaceutically acceptable salts or mixtures thereof, wherein A1 is nitrogen; A2 is carbon; Rl is independently selected from the group consisting of aryl or 5-6 membered heterocyclic ring system; R2 and R3 are independently selected from the group consisting of H, alkyl, substituted alkyl, alkylaryl, alkylheteroaryl, aryl, or 5-6 membered heterocyclic ring system; provided R2 or R3 is H. The present invention also provides a pharmaceutical composition comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, in combination with a pharmaceutically acceptable carrier or diluents. The present invention also provides a method for the prophylaxis or treatment of a medical condition associated with protein kinase, by administering a pharmaceutically effective amount of the compound of formula (I) or salts thereof.
Abstract:
The invention provides compounds of the invention pharmaceutical compositions comprising a compound of the invention, processes for preparing compounds of the invention, intermediates useful for preparing compounds of the invention, and therapeutic methods for treating cancer and other topoisomerase mediated conditions.
Abstract:
Certain aspects provide a method for wireless communication by a first user-equipment (UE). The method generally includes determining a first configuration for communication with a second UE of one or more discovery messages on a sidelink channel and a second configuration for data communication with the second UE on the sidelink channel, wherein the first configuration is different than the second configuration, and communicating with the second UE in accordance with at least one of the first configuration or the second configuration.
Abstract:
Techniques for handling sidelink feedback signaling in situations where collisions would otherwise be experienced in a network communication link are shown and described. For example, sidelink feedback signaling handling techniques may provide for collision handling when sidelink HARQ is to be simultaneously transmitted with network communication radio interface uplink channel information (e.g., Uu HARQ, SR, CSI, etc.) on one or more Uu channel (e.g., PUCCH, PUSCH, etc.). In operation of sidelink feedback handling, a transmitter or intermediary UE of a sidelink communication link may decide whether and how to forward the sidelink HARQ to a corresponding base station. Other aspects and features are also claimed and described.