公开(公告)号：KR1020090004254A

公开(公告)日：2009-01-12

申请号：KR1020070068315

申请日：2007-07-06

Applicant: 전자부품연구원 ,  경기도

Inventor： 홍성민 ,  황학인

IPC: H01L21/20 ,  B82Y40/00

Abstract: A manufacturing method of a porous substrate for the film type thin film is provided to uniformly form the grain size of the film type thin film by controlling the pore size of substrate to nano scale. A silicon substrate including an electrode layer is prepared for manufacturing the porous substrate for the film type thin film. An aluminum layer for the porous layer formation is formed on the electrode layer. The porous layer is formed by preceding the substrate with the cathode oxidation process. The first porous layer is formed on a part of the aluminum layer with the first cathode oxidation process. The first porous layer is removed. The second porous layer is formed on the rest of the aluminum layer with the second cathode oxidation process.

Abstract translation: 提供薄膜型薄膜用多孔基材的制造方法，通过将基板的孔径控制为纳米尺度，均匀地形成薄膜型薄膜的粒径。 制备包括电极层的硅衬底用于制造用于膜型薄膜的多孔基底。 在电极层上形成用于形成多孔层的铝层。 多孔层通过在阴极氧化工艺之前的衬底之前形成。 第一多孔层通过第一阴极氧化工艺形成在铝层的一部分上。 去除第一多孔层。 第二多孔层通过第二阴极氧化工艺在铝层的其余部分上形成。

公开(公告)号：KR100848811B1

公开(公告)日：2008-07-28

申请号：KR1020060096202

申请日：2006-09-29

Applicant: 전자부품연구원

Inventor： 곽연화 ,  박순섭 ,  홍성민

IPC: C12M1/18 ,  C12M1/00

CPC classification number: C12M23/12 ,  C12M23/22 ,  C12M29/10 ,  C12M41/46

Abstract: 본 발명에 따른 세포 배양 환경 및 주화성 측정 장치는 투명한 기판상에 형성되며 세포 배양액을 수용하기 위한 제 1 웰, 기판상에 제 1 웰과 이격되어 형성되며 세포 배양액과 세포 반응물질을 수용하기 위한 제 2 웰 및 제 1 웰과 상기 제 2 웰을 서로 접속하는 채널을 포함하고, 제 1 웰 또는 제 2 웰에 세포의 배양환경을 감지하거나 세포 배양액을 감지하기 위한 센서가 적어도 하나 이상 내장되며, 제 2 웰의 일측은 세포 배양액 및 세포 반응물질의 배출을 위한 배출구를 더 포함한다.
따라서, 본 발명에 따른 세포 배양 환경 및 주화성 측정 장치는 세포의 실시간 관찰과 동시에 세포의 주화성에 따른 이동 측정이 용이하고, 장시간 배양이 가능하며, 웰의 내부에 구비된 센서를 이용하여 세포 배양액의 특성측정과 세포 배양 시 주변환경의 제어가 용이한 효과가 있다.
세포 배양, 온도 센서, pH 센서, 표면 실장 장치

公开(公告)号：KR100815074B1

公开(公告)日：2008-03-20

申请号：KR1020060104300

申请日：2006-10-26

Applicant: 전자부품연구원

Inventor： 홍성민 ,  박순섭 ,  곽연화

IPC: C12M3/00

CPC classification number: C12M23/22 ,  C12M41/00 ,  C12M41/14

Abstract: An incubator for cell culturing is provided to control environment adequate for small amount of multi-type cell culturing easily, observe a cell culturing process and an image in real time without opening an incubator, grow cells stably by automating the environment control required for the cell culturing and perform more accurate and reliable cell culturing. An incubator for cell culturing comprises: a cell culturing chip(230) which has an empty space to culture the cell; a culture solution inlet which is formed at one side of the cell culturing chip to supply a cell culture solution to the empty space; a culture solution outlet which is formed at one side of the cell culturing chip to discharge the cell culture solution; a lower heater(210) which is placed at a lower part of the cell culturing chip and consists of a transparent heat-resistant substrate where a pyrogen pattern(255) for supplying heat energy to the cell culturing chip and the cell culture solution is deposited; a side wall(220) which is located at the circumferential side of the lower heater to support an upper heater(215); a sensor portion(250) which is placed at the side wall to detect at least one cell culturing environment of temperature, moisture, CO2 concentration, oxygen concentration, pH and flux; the upper heater which is placed at an upper part and consists of a transparent heat-resistant substrate where a pyrogen pattern for supplying heat energy to an upper part of the incubator is deposited; a gas inlet(240) which penetrates through the upper heater; a gas outlet(245) which is placed at a point with a regular interval from the gas inlet and penetrates through the upper heater; and a controlling portion(290) which controls operation of the upper heater and the lower heater using a detection signal outputted from the sensor portion, wherein the transparent heat-resistant substrate is quartz or glass, the pyrogen is platinum or tantalum silicide and the side wall consists of teflon.

Abstract translation: 提供用于细胞培养的培养箱，以容易地控制足够少的多型细胞培养的环境，在不打开培养箱的情况下实时观察细胞培养过程和图像，通过使细胞所需的环境控制自动化来稳定地培养细胞 培养和进行更准确可靠的细胞培养。 用于细胞培养的培养箱包括：细胞培养芯片（230），其具有用于培养细胞的空白空间; 在细胞培养片的一侧形成的培养液入口，将细胞培养液供给到空间; 培养液出口，形成于细胞培养片的一侧，排出细胞培养液; 下部加热器（210），其放置在细胞培养片的下部，并由透明耐热基底组成，其中用于向细胞培养片提供热能的热原图案（255）和沉积的细胞培养溶液 ; 位于所述下加热器的周向侧以支撑上加热器（215）的侧壁（220）; 传感器部分（250），其被放置在侧壁处以检测至少一个细胞培养环境的温度，水分，CO 2浓度，氧浓度，pH和通量; 放置在上部的上部加热器由透明耐热基材构成，其中沉积有用于向培养箱的上部供应热能的热原图案; 穿过上加热器的气体入口（240）; 气体出口（245），其被放置在与气体入口一定间隔的点处，并穿过上加热器; 以及控制部（290），其使用从所述传感器部输出的检测信号来控制所述上加热器和所述下加热器的动作，所述透明耐热基板为石英或玻璃，所述热原为铂或硅化钽，所述侧 墙由特氟隆组成。