公开(公告)号：KR101082484B1

公开(公告)日：2011-11-11

申请号：KR1020070112804

申请日：2007-11-06

Applicant: 한국과학기술원

Inventor： 박찬범 ,  구숙희 ,  기리고스와미코엘리 ,  유정기

IPC: G01N33/15

Abstract: 본발명에따르면, 기존의에서수행하였던아밀로이드단백질침작에의한신경질환치료제의스크리닝을고체기판상에서경제적이고, 간편하게수행할수 있어, 퇴행성신경질환치료제개발에매우유용하다.

公开(公告)号：KR101077622B1

公开(公告)日：2011-10-27

申请号：KR1020090012028

申请日：2009-02-13

Applicant: 한국과학기술원

Inventor： 박찬범 ,  이상하

IPC: C12N9/02 ,  C12N9/96

Abstract: 본발명에따라크산텐염료를이용하여옥시도리덕타제보조인자를재생하면, 빠른속도로옥시도리덕타제보조인자를재생시킬수 있어, 옥시도리덕타제효소를이용하는다양한생촉매반응의효율을높이는데유용하게사용될수 있다.

公开(公告)号：KR1020110065231A

公开(公告)日：2011-06-15

申请号：KR1020090122115

申请日：2009-12-09

Applicant: 한국과학기술원

Inventor： 박찬범 ,  임성윤 ,  이준석

IPC: C12Q1/26 ,  B82B3/00 ,  C12Q1/54 ,  G01N33/66

CPC classification number: C12Q1/26 ,  C12Q1/54 ,  C12Y101/03004 ,  G01N21/33 ,  G01N33/66

Abstract: PURPOSE: A method for detecting biomolecule using an alginate matrix in which gold nanoparticles and biomolecular oxidase are encapsulated is provided to detect biomolecules. CONSTITUTION: A method for detecting biomolecule using an alginate matrix in which gold nanoparticles and biomolecular oxidase are encapsulated comprises: a step of preparing the capsulated alginate matrix; a step of reacting the capsulated alginate matrix with a biomolecule; a step of adding a gold nanoparticule growth solution to a culture medium of alginate matrix and biomolecule; and a step of detecting the biomolecule using the size of the gold nanoparticle. The biomolecule is saccharides, proteins, lipids, or inorganic molecules.

Abstract translation: 目的：提供一种使用藻酸盐基质检测生物分子的方法，其中包含金纳米颗粒和生物分子氧化酶，以检测生物分子。 构成：使用其中包封金纳米颗粒和生物分子氧化酶的藻酸盐基质检测生物分子的方法包括：制备包封的藻酸盐基质的步骤; 使包封的藻酸盐基质与生物分子反应的步骤; 将金纳米颗粒生长溶液加入到藻酸盐基质和生物分子的培养基中的步骤; 以及使用金纳米颗粒的尺寸检测生物分子的步骤。 生物分子是糖，蛋白质，脂质或无机分子。

公开(公告)号：KR1020110012964A

公开(公告)日：2011-02-09

申请号：KR1020090070903

申请日：2009-07-31

Applicant: 한국과학기술원

Inventor： 박찬범 ,  유정기 ,  이민아

IPC: B82B3/00 ,  B82B1/00

CPC classification number: B82B3/0038 ,  B82B1/008 ,  B82Y20/00 ,  B82Y40/00

Abstract: PURPOSE: A luminescent peptide nanostructure is provided to easily synthesize a nanostructure in which luminous bodies are uniformly dispersed through simple mixing of a solution using a self-assembly property of peptide. CONSTITUTION: A method for preparing a luminescent peptide nanostructure comprises the steps of: (i) dissolving peptide in an organic solvent; (ii) preparing a solution in which at least one of lanthanum-based ions or salicylic acids are dissolved; and mixing the peptide solution of step (i) and the solution of step (ii) to prepare a luminescent peptide nanostructure in which the combination of the peptide and lanthanum-based ions or salicylic acids is self-assembled.

Abstract translation: 目的：提供发光肽纳米结构，以便通过使用肽的自组装性简单混合溶液来容易地合成其中发光体均匀分散的纳米结构。 构成：制备发光肽纳米结构的方法包括以下步骤：（i）将肽溶于有机溶剂中; （ii）制备其中溶解有镧基离子或水杨酸中的至少一种的溶液; 并将步骤（i）的肽溶液和步骤（ii）的溶液混合以制备发光肽纳米结构，其中肽和镧基离子或水杨酸的组合是自组装的。

公开(公告)号：KR1020100060645A

公开(公告)日：2010-06-07

申请号：KR1020080119327

申请日：2008-11-28

Applicant: 한국과학기술원

Inventor： 박찬범 ,  유정기

IPC: B82B3/00 ,  B82B1/00 ,  B82Y40/00

Abstract: PURPOSE: A method for preparing peptide nanostructures is provided to produce nanomaterial having various chemical properties and to easily control the nanostructures using a self-assembly process of biomolecules. CONSTITUTION: A method for preparing peptide nanosturctures comprises the following steps: dissolving peptide causing self-assembly in volatile organic solvent; forming an amorphous peptide thin film by coating a substrate with the solution; processing the amorphous peptide thin film using a thermal treatment, a chemical treatment, or physical treatment; growing peptide nanostructures through the self-assembly of the peptide. The peptide is added with a ratio of 0.05-20 parts by weight based on the volatile organic solvent 100.0 parts by weight.

Abstract translation: 目的：提供一种制备肽纳米结构的方法，以制备具有各种化学性质的纳米材料，并使用生物分子的自组装方法容易地控制纳米结构。 构成：制备肽纳米管的方法包括以下步骤：使肽在挥发性有机溶剂中自组装; 通过用溶液涂布基底来形成无定形肽薄膜; 使用热处理，化学处理或物理处理来处理无定形肽薄膜; 通过肽的自组装增长肽纳米结构。 相对于挥发性有机溶剂100.0重量份，添加0.05〜20重量份的肽。