公开(公告)号：KR1020040017697A

公开(公告)日：2004-02-27

申请号：KR1020020050123

申请日：2002-08-23

Applicant: 한국전자통신연구원

Inventor： 윤현철 ,  고종수 ,  양해식 ,  박세호 ,  표현봉 ,  정광효 ,  김성진 ,  김윤태

IPC: G01N27/26

Abstract: PURPOSE: A reproducible electrochemical bio sensor and a reproducing method thereof are provided to reuse an electrochemical bio sensor by reproducing the electrochemical bio sensor while maintaining high sensitivity. CONSTITUTION: An electrochemical bio sensor(100) includes a substrate(101), an electrode(102) formed on the substrate(101), and a bio material detecting layer(110). The substrate(101) includes silicon or glass. The electrode(102) is formed on the substrate(101) through a sputtering process or an evaporation process. The bio material detecting layer(110) includes a high polymer self-assembly single molecule layer(103). The bio material detecting layer(110) is spaced from a surface of the substrate(101) within a few nano meters. The high polymer self-assembly single molecule layer(103) is reacted with a binder(104) so that the binder(104) is immobilized into the high polymer self-assembly single molecule layer(103), thereby forming the bio material detecting layer(110).

Abstract translation: 目的：提供可再现的电化学生物传感器及其再现方法，以通过再现电化学生物传感器同时保持高灵敏度来再利用电化学生物传感器。 构成：电化学生物传感器（100）包括衬底（101），形成在衬底（101）上的电极（102）和生物材料检测层（110）。 基板（101）包括硅或玻璃。 电极（102）通过溅射法或蒸发法形成在基板（101）上。 生物材料检测层（110）包括高分子自组装单分子层（103）。 生物材料检测层（110）在几纳米内与衬底（101）的表面间隔开。 高分子自组装单分子层（103）与粘合剂（104）反应，使得粘合剂（104）固定在高分子自组装单分子层（103）中，从而形成生物材料检测层 （110）。

公开(公告)号：KR100407822B1

公开(公告)日：2003-12-01

申请号：KR1020010076229

申请日：2001-12-04

Applicant: 한국전자통신연구원

Inventor： 윤현철 ,  양해식 ,  전치훈 ,  김윤태

IPC: G01N27/327

CPC classification number: B82Y30/00 ,  B82Y15/00 ,  G01N33/5438 ,  G01N33/54393 ,  G01N33/581 ,  G01N2333/902 ,  G01N2333/908 ,  G01N2333/916

Abstract: An electrochemical immunosensor including a biological sensor layer with an antigen or a ligand residue immobilized thereon, and a biochemical analyte detection kit and method for electrochemically signaling a biological reaction occurring in the biological sensor layer are provided. The electrochemical immunosensor includes a substrate, an electrode or an electrode array formed on the substrate, and a biological sensor layer formed on the electrode or the electrode array and including a polymeric dendrimer monolayer with an antigen or a ligand residue immobilized on the surface thereof. The biological sensor layer further includes an adhesive layer for biomolecular immobilization between the electrode and the polymeric dendrimer monolayer.

Abstract translation: 提供了一种电化学免疫传感器，其包括其上固定有抗原或配体残基的生物传感器层以及用于电化学发信号通知生物传感器层中发生的生物反应的生化分析物检测试剂盒和方法。 电化学免疫传感器包括基底，在基底上形成的电极或电极阵列，以及形成在电极或电极阵列上的生物传感器层，并且包括聚合树枝状大分子单层，其表面上固定有抗原或配体残基。 生物传感器层还包括用于生物分子固定在电极和聚合树枝状大分子单层之间的粘合层。

公开(公告)号：KR1020010064276A

公开(公告)日：2001-07-09

申请号：KR1019990062430

申请日：1999-12-27

Applicant: 한국전자통신연구원

Inventor： 양해식 ,  김윤태

IPC: G01N33/483

CPC classification number: C12Q1/002

Abstract: PURPOSE: An enzyme electrode sensor and a method for manufacturing the same are provided to improve selectivity by restraining interference of organic obstacle material. CONSTITUTION: An enzyme electrode sensor includes an electrode(11), a non-conductive high molecule film(12) formed at the outside of the electrode, electrochemically polymerized, and in which enzyme is fixed, a non-conductive high molecule film(13) electrochemically polymerized, in which enzyme is not fixed, and formed at the outside of the non-conductive high molecule film in which enzyme is fixed, and an external film(14) formed at the outside of the non-conductive high molecule film in which enzyme is not fixed.

Abstract translation: 目的：提供酶电极传感器及其制造方法，通过抑制有机障碍物的干扰来提高选择性。 构成：酶电极传感器包括电极（11），在电极外部形成的非导电性高分子膜（12），电化学聚合，固定有酶的非导电性高分子膜（13） ）电化学聚合，其中酶不固定，并且在固定有酶的非导电性高分子膜的外侧形成，并且在非导电性高分子膜的外侧形成外部膜（14） 哪个酶不固定。