公开(公告)号：EP2158178A1

公开(公告)日：2010-03-03

申请号：EP08771944.9

申请日：2008-06-25

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  BAGHERZADEH, Ebrahim ,  ANTHONY, Rayford G. ,  BORSINGER, Gregory ,  HASSAN, Aziz

IPC: C07C45/49 ,  C07C49/04 ,  B01F7/26

CPC classification number: B01J19/1806 ,  B01F7/00766 ,  B01F13/1013 ,  B01F13/1016 ,  B01J8/025 ,  B01J8/20 ,  B01J19/0066 ,  B01J2219/00006 ,  B01J2219/00779 ,  C07C45/50 ,  C07C49/04

Abstract: Methods and systems for preparing dialkyl ketones are described herein. The methods and systems incorporate the novel use of a high shear device to promote dispersion and solubility of carbon monoxide and hydrogen with the olefins (e.g. ethylene) in a liquid solvent. The high shear device may allow for lower reaction temperatures and pressures and may also reduce reaction time.

公开(公告)号：EP2158175A2

公开(公告)日：2010-03-03

申请号：EP08771282.4

申请日：2008-06-17

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  BAGHERZADEH, Ebrahim ,  ANTHONY, Rayford G. ,  BORSINGER, Gregory ,  HASSAN, Aziz

IPC: C07C13/18 ,  C07C5/10 ,  B01F7/26

CPC classification number: B01J19/1806 ,  B01F7/00766 ,  B01F13/1013 ,  B01F13/1016 ,  B01J8/025 ,  B01J8/20 ,  B01J19/0066 ,  B01J2219/00006 ,  B01J2219/00779 ,  C07C5/10 ,  C07C2523/06 ,  C07C2523/14 ,  C07C2523/26 ,  C07C2523/28 ,  C07C2523/34 ,  C07C2523/72 ,  C07C2523/745 ,  C07C2523/75 ,  C07C2523/755 ,  C07C2601/14 ,  C07C13/18

Abstract: A high shear mechanical device incorporated into a process and system for the production of cyclohexane is capable of decreasing mass transfer limitations, thereby enhancing the cyclohexane production process. A system for the production of cyclohexane from benzene and hydrogen, the system comprising a reactor, solid catalyst, and a high shear device, the outlet of which is fluidly connected to the inlet of the reactor; the high shear device capable of providing an emulsion of hydrogen gas bubbles within a liquid comprising benzene, the bubbles having an average bubble diameter of less than about 100 μm.

Abstract translation: 结合到生产环己烷的方法和体系中的高剪切机械装置能够降低传质限制，从而增强环己烷的制备方法。 用于从苯和氢生产环己烷的系统，该系统包括反应器，固体催化剂和高剪切装置，其出口流体地连接到反应器的入口; 高剪切装置能够在包含苯的液体中提供氢气气泡的乳液，气泡的平均气泡直径小于约100μm。

公开(公告)号：EP2155651A1

公开(公告)日：2010-02-24

申请号：EP08780995.0

申请日：2008-06-25

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  BAGHERZADEH, Ebrahim ,  ANTHONY, Rayford, G. ,  BORSINGER, Gregory ,  HASSAN, Aziz

IPC: C07C67/00 ,  C07C69/02 ,  B01F7/26

CPC classification number: B01F13/1013 ,  B01F7/00766 ,  B01F13/1016 ,  B01J8/20 ,  B01J8/222 ,  C07C67/08 ,  Y02P20/127 ,  Y02P20/582 ,  C07C69/14

Abstract: Methods and systems for the production of ethyl acetate are described herein. The methods and systems incorporate the novel use of a high shear device to promote dispersion and mixing of a carbonyl co-reactant (e.g. acetic acid, acetaldehyde) with ethanol. The high shear device may allow for lower reaction temperatures and pressures and may also reduce reaction time with existing catalysts.

公开(公告)号：EP2152406A1

公开(公告)日：2010-02-17

申请号：EP08771917.5

申请日：2008-06-25

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  BAGHERZADEH, Ebrahim ,  ANTHONY, Rayford, G. ,  BORSINGER, Gregory ,  HASSAN, Aziz

IPC: B01J21/06 ,  B01J35/02 ,  C07C31/04 ,  C07C29/151 ,  B01F7/26

CPC classification number: B01F7/00766 ,  B01F13/1013 ,  B01F13/1016 ,  B01J8/0278 ,  B01J8/222 ,  B01J19/1806 ,  B01J19/1862 ,  B01J23/002 ,  B01J23/8892 ,  B01J37/0236 ,  B01J37/03 ,  B01J2208/0053 ,  B01J2219/00083 ,  B01J2219/00159 ,  B01J2523/00 ,  C10G2/00 ,  C10G50/00 ,  C10G2300/1025 ,  Y02P30/20 ,  Y10S585/922 ,  B01J2523/3706 ,  B01J2523/69 ,  B01J2523/72 ,  B01J2523/845 ,  B01J2523/12

Abstract: A method for producing a product comprising at least one selected from C2+ hydrocarbons, oxygenates, and combinations thereof from light gas comprising one or more of carbon dioxide, methane, ethane, propane, butane, pentane, and methanol by forming a dispersion of light gas in a liquid feed, wherein the dispersion is formed at least in part with high shear forces and wherein at least one of the liquid feed and the light gas is a hydrogen source. A system for carrying out the method is also presented.

公开(公告)号：EP2152378A2

公开(公告)日：2010-02-17

申请号：EP08771909.2

申请日：2008-06-25

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  BAGHERZADEH, Ebrahim ,  ANTHONY, Rayford, G. ,  BORSINGER, Gregory ,  HASSAN, Aziz

IPC: B01D3/40 ,  C07C53/02 ,  A61K31/616 ,  B01F7/26

CPC classification number: B01J19/1806 ,  B01F7/00766 ,  B01F13/1013 ,  B01F13/1016 ,  B01J8/025 ,  B01J8/20 ,  B01J19/0066 ,  B01J2219/00006 ,  B01J2219/00779 ,  C07C67/08 ,  Y02P20/582 ,  C07C69/157

Abstract: Use of a high shear mechanical device in a process for production of acetyl salicylic acid, by contacting acetic anhydride with salicylic acid in a high shear device. The disclosed process makes possible a decrease in mass transfer limitations, thereby enhancing production of acetyl salicylic acid. A system for production of acetyl salicylic acid is also provided in which a reactor is configured to receive the output from a high shear device, which is configured to receive, via one or more inlets, acetic anhydride, and salicylic acid and generate a fine dispersion or emulsion of reactants.

公开(公告)号：EP2137129A1

公开(公告)日：2009-12-30

申请号：EP08771007.5

申请日：2008-06-13

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  BAGHERZADEH, Ebrahim ,  ANTHONY, Rayford, G. ,  BORSINGER, Gregory ,  HASSAN, Aziz

IPC: C07C65/21 ,  C07C65/05 ,  C07C69/78

CPC classification number: C07C51/265 ,  B01F7/00766 ,  B01F13/1013 ,  B01F13/1016 ,  B01J8/222 ,  B01J19/1806 ,  C07C63/16 ,  C07C63/26 ,  C07C63/24 ,  C07C63/06

Abstract: A method for producing benzoic acid or a methylbenzoic acid isomer is disclosed which comprises forming a dispersion comprising oxygen-containing gas bubbles dispersed in either toluene or an xylene isomer, wherein the bubbles have a mean diameter less than 1 micron. The dispersion is then subjected to reaction conditions comprising a pressure of less than about 1013 kPa and a temperature of less than about 160° C., whereby at least a portion of the toluene or xylene isomer is partially oxidized to form benzoic acid or the corresponding methylbenzoic acid isomer, respectively. In some embodiments, the methylbenzoic acid isomer is an intermediate compound, and the method further includes subjecting any unreacted xylene isomer and the intermediate compound to further oxidization, to form 1,2-benzenedicarboxylic acid, 1,3-benzenedicarboxylic acid, or 1,4-benzenedicarboxylic acid. A system of apparatus for performing the method is also disclosed.

公开(公告)号：EP2137128A1

公开(公告)日：2009-12-30

申请号：EP08770729.5

申请日：2008-06-11

Applicant: H R D Corporation

Inventor： BAGHERZADEH, Ebrahim ,  HASSAN, Abbas ,  ANTHONY, Rayford G. ,  BORSINGER, Gregory R. ,  HASSAN, Aziz

IPC: C07C51/54 ,  C07C51/12 ,  C07C51/15

CPC classification number: C07C51/56 ,  B01F7/00766 ,  B01F13/1013 ,  B01F13/1016 ,  B01J8/025 ,  B01J8/20 ,  B01J19/0066 ,  B01J19/1806 ,  B01J2219/00006 ,  B01J2219/00779 ,  Y02P20/582 ,  C07C53/12

Abstract: A system and method for a high shear mechanical device incorporated into a process for the production of acetic anhydride as a reactor device is shown to be capable of decreasing mass transfer limitations, thereby enhancing the process. A system for the production of acetic anhydride including the mixing of catalyst and acetic acid via a high shear device.

公开(公告)号：EP2134700A2

公开(公告)日：2009-12-23

申请号：EP08770988.7

申请日：2008-06-13

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  BAGHERZADEH, Ebrahim ,  ANTHONY, Rayford G. ,  BORSINGER, Gregory ,  HASSAN, Aziz

IPC: C07D333/48 ,  C08F34/04

CPC classification number: C07D333/48 ,  B01F7/00766 ,  B01F13/1013 ,  B01F13/1016 ,  B01J19/0066 ,  B01J19/1806 ,  B01J2219/00006 ,  B01J2219/00177 ,  B01J2219/00189

Abstract: Use of a high shear mechanical device incorporated into a process for the production of sulfolene as a reactor device is capable of decreasing mass transfer limitations, thereby enhancing the sulfolene production process. A system for the production of sulfolene from butadiene and sulfur dioxide, the system comprising a reactor and an external high shear mixer the outlet of which is fluidly connected to the inlet of the reactor; the high shear mixer capable of providing a dispersion of sulfur dioxide gas bubbles within a liquid, the bubbles having an average bubble diameter of less than about 100μm.

公开(公告)号：EP2125168A2

公开(公告)日：2009-12-02

申请号：EP08771802.9

申请日：2008-06-24

Applicant: H R D Corporation

Inventor： HASSAN, Abbas ,  BAGHERZADEH, Ebrahim ,  ANTHONY, Rayford, G. ,  BORSINGER, Gregory ,  HASSAN, Aziz

IPC: B01D53/52 ,  B01D53/14 ,  C01B17/04

CPC classification number: B01D53/8612 ,  B01D53/77 ,  B01D53/96 ,  B01D2251/11 ,  B01D2255/20738 ,  C01B17/05 ,  C10L3/10 ,  C10L3/102 ,  Y02E50/346 ,  Y02E60/36 ,  Y02P20/584

Abstract: A method for removing hydrogen sulfide from a sour gas stream comprising hydrogen sulfide by oxidizing hydrogen sulfide in a converter by contacting the sour gas stream with an aqueous catalytic solution, thereby producing a desulfurized gas stream and a liquid stream comprising reduced catalyst and elemental sulfur, introducing an oxidant and the liquid stream comprising reduced catalyst and elemental sulfur into a high shear device and producing a dispersion wherein the mean bubble diameter of the oxidant gas in the dispersion is less than about 5 microns, introducing the dispersion into a vessel from which a sulfur-containing slurry is removed and a regenerated catalyst stream is removed, wherein the sulfur slurry comprises elemental sulfur and aqueous liquid, and recycling at least a portion of the regenerated catalyst stream to the converter. A system of apparatus for carrying out the method is also provided.

公开(公告)号：WO2011139478A2

公开(公告)日：2011-11-10

申请号：PCT/US2011/031725

申请日：2011-04-08

Applicant: H R D CORPORATION ,  HASSAN, Abbas ,  HASSAN, Aziz ,  ANTHONY, Rayford G.

Inventor： HASSAN, Abbas ,  HASSAN, Aziz ,  ANTHONY, Rayford G.

IPC: A61M5/14 ,  A61M5/142 ,  A61M5/168 ,  A61J3/00 ,  A61K9/10

CPC classification number: A61J3/00 ,  A61K9/0019 ,  A61M5/142 ,  B01F7/00766 ,  B01F7/008 ,  B01F13/1016

Abstract: In this disclosure, a method is described wherein the method comprises mixing a therapeutic gas or a therapeutic liquid or a combination thereof and a liquid carrier in a high shear device to produce a dispersion; and administering the produced dispersion intravenously to a patient; wherein the produced dispersion contains nanobubbles of the therapeutic gas or droplets of the therapeutic liquid with a mean diameter of less than about 1.5 μm. In this disclosure, a system is also described wherein the system comprises a therapeutic gas source or a therapeutic liquid source or a combination thereof; a liquid carrier source; a high shear device (HSD) having an inlet, an outlet, at least one rotor, and at least one stator separated by a shear gap; and a pump configured to control the flow rate and residence time of a fluid passing through the high shear device.

Abstract translation: 在本公开中，描述了一种方法，其中所述方法包括在高剪切装置中混合治疗气体或治疗液体或其组合和液体载体以产生分散体; 并将产生的分散体静脉内施用于患者; 其中所制备的分散体含有平均直径小于约1.5μm的治疗液体的治疗气体或液滴的纳米气泡。 在本公开中，还描述了一种系统，其中系统包括治疗气体源或治疗液体源或其组合; 液体载体源; 具有入口，出口，至少一个转子和由剪切间隔分开的至少一个定子的高剪切装置（HSD）; 以及构造成控制通过高剪切装置的流体的流速和停留时间的泵。