公开(公告)号：WO2012177933A1

公开(公告)日：2012-12-27

申请号：PCT/US2012/043623

申请日：2012-06-21

Applicant: PY, Daniel

Inventor： PY, Daniel

IPC: A61L2/00

CPC classification number: B65B55/10 ,  B65B25/001 ,  B65B25/008

Abstract: A method for sterilizing a container is provided where a penetrable septum of a sealed empty device is penetrated with an injection member. A fluid sterilant is then injected through the injection member and into an interior chamber of the device. The fluid sterilant is allowed to reside within the chamber a sufficient amount of time to render the chamber either sterile or bactericidal. Product can then be introduced through the septum into the sterile or bactericidal chamber. The resulting penetration aperture is then resealed to hermetically seal the product within the chamber.

Abstract translation: 提供了一种用于对容器进行灭菌的方法，其中密封的空装置的可穿透的隔膜用注射构件穿透。 然后将流体灭菌剂通过注射构件注入装置的内部室中。 允许流体灭菌剂在室内停留足够的时间以使得室无菌或杀菌。 然后将产品通过隔膜引入无菌或杀菌室。 然后将所得到的穿透孔重新密封以将产品气密密封在腔室内。

公开(公告)号：WO2011137413A1

公开(公告)日：2011-11-03

申请号：PCT/US2011/034703

申请日：2011-04-30

Applicant: MEDICAL INSTILL TECHNOLOGIES, INC. ,  PY, Daniel ,  CHAN, Julian ,  WILLEY, Jeffrey

Inventor： PY, Daniel ,  CHAN, Julian ,  WILLEY, Jeffrey

IPC: A61J9/00

CPC classification number: A61J9/00 ,  A61J1/2093

Abstract: A container including a body defining an outflow opening and at least one chamber adapted for storing a product, such as a fat containing liquid product, and a container closure including a primary seal for hermetically sealing the product within the chamber during storage. The container closure includes a sealing member forming a substantially fluid-tight seal between the container closure and the body, and a dispensing member in fluid communication with the chamber. The container closure and body move relative to each other between a first position where the primary seal is seated about the outflow port to hermetically seal the product in the chamber during storage, and a second position where the primary seal is displaced from the outflow port to allow product to pass from the chamber through the outflow port and into dispensing member to dispense the product.

Abstract translation: 一种容器，其包括限定流出开口的主体和适于储存产品（例如含脂肪的液体产品）的至少一个室，以及容器盖，该容器封闭件包括用于在储存期间气密地密封室内的产品的主密封件。 容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件和与腔室流体连通的分配构件的密封构件。 容器封闭件和主体在第一位置和第二位置之间移动，第一位置和第二位置之间，第一位置处主要密封件围绕流出端口安置，以便在存储期间将产品气密地密封在腔室中;以及第二位置，其中主密封件从流出端口移位到 允许产品从腔室通过流出口并进入分配构件以分配产品。

公开(公告)号：WO2010042902A1

公开(公告)日：2010-04-15

申请号：PCT/US2009/060284

申请日：2009-10-09

Applicant: PY, Daniel

Inventor： PY, Daniel

IPC: B32B23/00

CPC classification number: B65D47/24 ,  B05B11/3028 ,  B29C47/0021 ,  B29C47/0023 ,  B29C47/0026 ,  B29C47/065 ,  B29C47/068 ,  B29C49/04 ,  B29L2009/00 ,  B29L2031/7158 ,  B65D23/02 ,  B65D47/205 ,  B65D47/32

Abstract: A device comprises a first portion including a first polymer, and a second portion that is relatively flexible in comparison to the first portion and includes a second polymer that is substantially not bondable to the first polymer. A chamber of the device is hermetically sealable with respect to ambient atmosphere and is defined by (i) an interior of the second portion, and/or (ii) a space formed between the first and second portions. A third portion of the device includes a third polymer that is bondable to the first and second polymers and fixedly secures the first and second portions to each other.

Abstract translation: 一种装置包括包含第一聚合物的第一部分和与第一部分相比具有相对柔性的第二部分，并且包括基本上不能与第一聚合物结合的第二聚合物。 该装置的腔室相对于环境气氛可密封，并且由（i）第二部分的内部和/或（ii）形成在第一和第二部分之间的空间限定。 该装置的第三部分包括可与第一和第二聚合物结合的第三聚合物，并将第一和第二部分彼此固定地固定。

公开(公告)号：WO2010042897A1

公开(公告)日：2010-04-15

申请号：PCT/US2009/060278

申请日：2009-10-09

Applicant: PY, Daniel

Inventor： PY, Daniel

IPC: B29C47/00

CPC classification number: B65D1/0215 ,  A61J1/05 ,  A61J1/1406 ,  A61J1/1412 ,  B05B11/0043 ,  B05B11/3028 ,  B29C47/003 ,  B29C47/004 ,  B29C49/04 ,  B29C49/22 ,  B29C65/665 ,  B29C66/7371 ,  B29C2791/001 ,  B29C2793/0027 ,  B29K2101/12 ,  B29L2031/565 ,  B65B3/04 ,  B65B7/16 ,  B65B51/22 ,  B65D1/0223 ,  B65D1/0276 ,  B65D1/0284 ,  B65D47/36 ,  B65D55/0818 ,  B65D77/06 ,  B65D2501/0036 ,  B65D2501/0063 ,  B65D2501/0072 ,  B67C2003/227

Abstract: A device comprising a body including a first polymer and a closure including a second polymer that is substantially not bondable to the first polymer and has a relatively higher shrinkage rate than the first polymer, wherein at least a portion of the closure overlaps at least a portion of the body, forming a hermetic seal there between and defining a sealed, empty, sterile container.

Abstract translation: 一种包括主体的装置，包括第一聚合物和封闭物，所述封闭物包括基本上不能与第一聚合物结合并且具有比第一聚合物相对较高的收缩率的第二聚合物，其中封闭物的至少一部分与至少一部分 的身体，在其间形成密封的密封，并且限定密封的空的无菌容器。

公开(公告)号：WO2008061041A3

公开(公告)日：2008-05-22

申请号：PCT/US2007/084356

申请日：2007-11-09

Applicant: MEDICAL INSTILL TECHNOLOGIES, INC. ,  PY, Daniel

Inventor： PY, Daniel

IPC: B67D5/40

Abstract: A dispenser for dispensing a substance has a body defining a variable-volume storage chamber for storing the substance, and a dispensing portion connected with the body and defining a dosage chamber coupled in fluid communication with the storage chamber for receiving substance there from, and an outlet aperture coupled in fluid communication with the dosage chamber. A first valve includes an axially-extending valve seat and an axially-extending flexible valve cover seated on the valve seat and defining a normally-closed, axially-extending seam there between forming a fluid-tight seal between the valve cover and valve seat. The flexible valve cover is movable relative to the valve seat and the seam is connectable in fluid communication with the outlet aperture to allow the passage of substance through the seam and out of the dispenser. A second valve is coupled in fluid communication between the dosage chamber and the storage chamber.

公开(公告)号：WO2008030623A2

公开(公告)日：2008-03-13

申请号：PCT/US2007/019715

申请日：2007-09-10

Applicant: MEDICAL INSTILL TECHNOLOGIES, INC. ,  PY, Daniel

Inventor： PY, Daniel

IPC: B67D5/00 ,  B65D35/56 ,  B65D37/00 ,  B67D5/06

CPC classification number: B67D1/10 ,  B05B11/0054 ,  B05B11/303 ,  B05B11/3032 ,  B65D75/5866 ,  B65D75/5883 ,  B65D77/067 ,  B67D1/0082 ,  B67D1/02 ,  B67D2001/0827

Abstract: An apparatus for storing fluid and dispensing multiple portions of the stored fluid has a container defining a variable-volume storage chamber; a dispensing valve including a valve inlet coupled in fluid communication with the variable-volume storage chamber, and an elastic valve member in fluid communication with the valve inlet and defining a normally-closed valve opening; a manually engageable actuator; and a pump including a compressible member defining a compression chamber coupled in fluid communication with the variable-volume storage chamber. Multiple portions of the stored fluid are hermetically sealed in the variable-volume storage chamber. The actuator is manually engageable and movable between (i) a first position wherein the compression chamber defines a first volume, and (ii) a second position wherein the compression chamber defines a second volume less than the first volume. In the second position the fluid in the compression chamber exceeds a valve opening pressure and, in turn, moves the elastic valve member between (i) a normally closed position hermetically sealing the one-way valve and variable-volume storage chamber with respect to ambient atmosphere, and (ii) an open position permitting fluid flow through the valve opening.

Abstract translation: 用于存储流体和分配存储流体的多个部分的装置具有限定可变容积的储存室的容器; 分配阀，包括与可变容积存储室流体连通的阀入口和与阀入口流体连通并限定常闭阀开口的弹性阀构件; 可手动接合的致动器; 以及泵，其包括限定与所述可变容积存储室流体连通地联接的压缩室的可压缩构件。 存储流体的多个部分气密地密封在可变容积的储存室中。 致动器可手动地接合并且可在（i）第一位置和第二位置之间移动，第一位置，其中压缩室限定第一容积，和（ii）第二位置，其中压缩室限定小于第一容积的第二容积。 在第二位置，压缩室中的流体超过阀打开压力，并且使弹性阀构件在（i）气密地将密闭单向阀和可变体积储存室的常闭位置相对于环境 （ii）允许流体流过阀门开口的打开位置。

公开(公告)号：WO2007136791A3

公开(公告)日：2007-11-29

申请号：PCT/US2007/011983

申请日：2007-05-18

Applicant: MAEJ, LLC ,  PY, Daniel

Inventor： PY, Daniel

IPC: B65D81/00

Abstract: A device and method are provided for storing medicaments and foods and/or beverages separately during shelf life, and for mixing the medicaments and foods and/or beverages when ready for use. A body of the device defines a plurality of first chambers for receiving a medicament, and a plurality of second chambers for receiving a food and/or beverage. A first sealing portion is located between the first and second chambers and is movable between a closed position preventing fluid communication between the chambers, and an open position permitting fluid communication between the first and second chambers for mixing the medicament and the food and/or beverage when ready for use. First and second penetrable and thermally resealable portions are in fluid communication with the first and second chambers, respectively, and are penetrable by an injection member to form an injection aperture therethrough and introduce the medicament or the food and/or beverage through the injection member and into the respective chamber, and are thermally resealable to seal the injection apertures and the medicament or food and/or beverage within the respective chamber by applying energy thereto.

公开(公告)号：WO2007117228A3

公开(公告)日：2007-10-18

申请号：PCT/US2006/002766

申请日：2006-01-25

Applicant: MEDICAL INSTILL TECHNOLOGIES, INC. ,  PY, Daniel ,  ASSION, Norbert ,  HOULE, Nathaniel ,  SAHOO, Debashis ,  WILLEY, M., Jeffrey ,  HARTMAN, Eric, E. ,  GUTHY, John

Inventor： PY, Daniel ,  ASSION, Norbert ,  HOULE, Nathaniel ,  SAHOO, Debashis ,  WILLEY, M., Jeffrey ,  HARTMAN, Eric, E. ,  GUTHY, John

IPC: B65D47/36 ,  B65D51/20 ,  B65D41/20

Abstract: The present invention consists of a container and closure assembly for a fat containing liquid product. The closure assembly further comprises a stopper, sealing member, and securing member. The container and closure assembly are made of materials which do not leach a significant amount of a leachable substance into the liquid product. Also disclosed is a method for filling the containers, comprising the steps of advancing a needle filling assembly through the closure assembly, filling the container, removing the needle assembly, and thermally sealing the needle aperture. These steps may also be preceded by the step of sterilizing the outside of the container with a liquid, then blowing away the liquid with a sterile gas before the container reaches the filling assembly.

公开(公告)号：WO2006099507A3

公开(公告)日：2006-09-21

申请号：PCT/US2006/009372

申请日：2006-03-13

Applicant: MEDICAL INSTILL TECHNOLOGIES, INC. ,  PY, Daniel

Inventor： PY, Daniel

IPC: B65B1/04 ,  B65D30/00

Abstract: Apparatus is provided for molding and filling a container. A barrier enclosure defines an aseptic chamber. A mold includes within the aseptic chamber plural mold cavities shaped to form the stopper and container body, An assembly device engageable with each of the container body and stopper is movable relative to the mold to engage and de-mold the substantially sterile stoppers and container bodies from the mold cavities. A source of sterile air is in fluid communication with the aseptic chamber and directs a flow of sterile air into the aseptic chamber and over the sterile surfaces of the mold for maintaining the sterility of the mold surfaces and stopper and container bodies during demolding. A needle filling and thermal resealing station is configured to receive the sealed, empty sterile containers, needle fill the interior chambers of the containers, and thermally reseal resulting needle holes in the stoppers.

公开(公告)号：WO2006063360A2

公开(公告)日：2006-06-15

申请号：PCT/US2005/045110

申请日：2005-12-12

Applicant: MEDICAL INSTILL TECHNOLOGIES, INC. ,  PY, Daniel ,  CHAN, Julian, V.

Inventor： PY, Daniel ,  CHAN, Julian, V.

IPC: B65D37/00

CPC classification number: B65D35/46 ,  B65D47/205 ,  B65D47/2056 ,  B65D47/2081

Abstract: A container and valve assembly for storing and dispensing substances including edible substances. The container is a tubular body that defines a storage chamber for storing the substance and a head portion for supports the valve assembly. The valve assembly includes a valve body and a valve seat surrounded by a flexible outer cover that includes a valve portion. A seem between the valve portion and valve seat form a one-way release valve wherein a portion of the seam remains closed when the substance is dispensed. To dispense the substance, pressure is applied to the body forcing the substance into the valve assembly, which in turn, controls the flow and release of the substance without exposing the remaining substance to the external atmosphere; thus, the sterility of the storage chamber and remaining substance is maintained, and the shelf life of the substance is increased.

Abstract translation: 用于储存和分配包括可食用物质的物质的容器和阀组件。 容器是限定用于储存物质的储存室的管状体和用于支撑阀组件的头部。 阀组件包括阀体和由包括阀部分的柔性外盖包围的阀座。 在阀部分和阀座之间似乎形成单向释放阀，其中当物质被分配时，接缝的一部分保持关闭。 为了分配物质，将压力施加到身体，迫使物质进入阀组件，这进而控制物质的流动和释放，而不将剩余物质暴露于外部大气; 因此，保持储存室和剩余物质的不育性，并且物质的保存期限增加。