Abstract:
Exemplary apparatus for obtaining information for a structure can be provided. For example, the exemplary apparatus can include at least one first optical f fiber arrangement which is configured to transcribe at least one first electro-magnetic radiation, and can include at least one fiber. The exemplary apparatus can also include at least one second focusing arrangement in optical communication with the optical fiber arrangement. The second arrangement can be configured to focus and provide there through the first electro-magnetic radiation. Further, the exemplary apparatus can include at least one third dispersive arrangement which is configured to receive a particular radiation which is the first electro-magnetic radiation and/or the focused electro-magnetic radiation, and forward a dispersed radiation thereof to at least one section of the structure. At least one end of the fiber can be directly connected to the second focusing arrangement and/or the third dispersive arrangement. In addition, an exemplary embodiment of a method for producing an optical arrangement can be provided.
Abstract:
Exemplary apparatus for obtaining information for a structure can be provided. For example, the exemplary apparatus can include at least one first optical fiber arrangement which is configured to transceive at least one first electro-magnetic radiation, and can include at least one fiber. The exemplary apparatus can also include at least one second focusing arrangement in optical communication with the optical fiber arrangement. The second arrangement can be configured to focus and provide there through the first electro-magnetic radiation. Further, the exemplary apparatus can include at least one third dispersive arrangement which is configured to receive a particular radiation which is the first electro-magnetic radiation and/or the focused electro-magnetic radiation, and forward a dispersed radiation thereof to at least one section of the structure. At least one end of the fiber can be directly connected to the second focusing arrangement and/or the third dispersive arrangement. In addition, an exemplary embodiment of a method for producing an optical arrangement can be provided. For example, a first set of optical elements having a first size in a first configuration and a second set of optical elements in cooperation with the second set and having a second size in a second configuration can be provided. The first and second sets can be clamped into a third set of optical elements. The third set can be polished, and a further set of optical elements may be deposited on the polished set.
Abstract:
A system and method for obtaining fluorescence images from a sample are provided. Broadband excitation light (302) is encoded with a wavelength-dependent frequency modulation and dispersed onto a sample (314), e.g. with a grating (316a), to simultaneously illuminate an entire image line. The frequency-encoded fluorescence emission is measured to provide one line of the image. Mechanical scanning along a direction orthogonal to the wavelength-encoded axis allows creation of a two-dimensional fluorescence image. The system and method is especially useful for obtaining fluorescence images via endoscopes, catheters, or small-diameter probes.
Abstract:
Apparatus, catheter and method for obtaining information regarding a tissue structure (e.g., a blood vessel) can be provided. For example, it is possible to utilize a transceiving arrangement which includes at least one section adapted to be provided in a proximity of at least one portion of the tissue structure and in a bodily fluid, and which is adapted to transmit and receive electro-magnetic radiation. The bodily fluid may be blood, pus, necrotic debris, mucus, urine and/or fecal matter.
Abstract:
Apparatus, catheter and method for obtaining information regarding a tissue structure (e.g., a blood vessel) can be provided. For example, it is possible to utilize a transceiving arrangement which includes at least one section adapted to be provided in a proximity of at least one portion of the tissue structure and in a bodily fluid, and which is adapted to transmit and receive electro-magnetic radiation. The bodily fluid may be blood, pus, necrotic debris, mucus, urine and/or fecal matter.
Abstract:
A system, process and software arrangement are provided to determining data associated with at least one structural change of tissue. In particular, a first optical coherence tomography ("OCT") signal which contains first information regarding the tissue at a first stress level, and a second OCT signal which contains second information regarding the tissue at a second stress level are received. The first and second information are compared to produce comparison information. The data associated with the at least one structural change is determined as a function of the comparison information and further information associated with (i) at least one known characteristics of the tissue and/or (ii) characteristics of an OCT system. Further, at least one optical coherence tomography ("OCT") signal which contains information regarding the tissue can be received, and the modulus of the tissue may be determined as a function of the received at least one OCT signal.
Abstract:
A method and apparatus for obtaining three-dimensional surface measurements using phase-sensitive spectrally encoded imaging is described. Both transverse and depth information is transmitted through a single-mode optical fiber, allowing this technique to be incorporated into a miniature probe.
Abstract:
An apparatus and source arrangement for filtering an electromagnetic radiation can be provided which may include at least one spectral separating arrangement configured to physically separate one or more components of the electromagnetic radiation based on a frequency of the electromagnetic radiation. The apparatus and source arrangement may also have at least one continuously rotating optical arrangement which is configured to receive at least one signal that is associated with the one or more components. Further, the apparatus and source arrangement can include at least one beam selecting arrangement configured to receive the signal.
Abstract:
Speckle, a factor reducing image quality in optical coherence tomography ("OCT"), can limit the ability to identify cellular structures that are important for the diagnosis of a variety of diseases. The present invention allows for an implementation of an angular compounding, angular compounding by path length encoding ("ACPE") for reducing speckle in OCT images. By averaging images obtained at different incident angles, with each image encoded by path length, ACPE maintains high-speed image acquisition and implements minimal modifications to OCT probe optics. ACPE images obtained from tissue phantoms and human skin in vivo demonstrate a qualitative improvement over traditional OCT and an increased signal-to-noise ratio ("SNR"). Accordingly, apparatus probe catheter, and method are provided for irradiating a sample. In particular, an interferometer (5) may forward forwarding an electromagnetic radiation (10). In addition, a sample arm may receive the electromagnetic radiation, and can include an arrangement (20) which facilitates a production of at least two radiations (30, 40) from the electromagnetic radiation so as to irradiate the sample. Such arrangement can be configured to delay a first radiation of the at least two radiations with respect to a second radiation of the at least two radiations.
Abstract:
A confocal microscope lens arrangement is provided. The confocal microscope lens arrangement includes a lens assembly housing which has a lens assembly, and an exterior housing including a distal end and a proximal end. The exterior housing is configured to allow the lens assembly housing to be placed therein, and translated between the proximal end and the distal end of the exterior housing to focus the lens assembly. The exterior housing has an aperture formed through a distal end thereof. The arrangement also includes an immersion media filling the volume of area between the exterior housing and the lens assembly housing.