公开(公告)号：US06521572B2

公开(公告)日：2003-02-18

申请号：US09731263

申请日：2000-12-05

Applicant: Daniel Perlman

Inventor： Daniel Perlman

IPC: C11D750

CPC classification number: A61K8/737 ,  A61K8/4973 ,  A61K8/73 ,  A61K8/731 ,  A61K8/732 ,  A61Q3/04

Abstract: A thickened nail polish-lacquer removing composition having a smooth, substantially non-granular consistency. The composition is substantially non-irritating and non-sensitizing to the skin surrounding the fingernails and toenails. Upon drying, the residue of the lacquer-removing composition is water-soluble. The composition includes from 51% to 99.9% by weight of butyrolactone organic solvent and/or a propylene glycol derivative solvent and from 0.1% to 5% by weight of at least one water-soluble thickening agent capable of functioning in the absence of a neutralizing agent, and which is present in an amount effective to produce an absolute kinematic viscosity at 20° C. of from 250-10,000 cp.

Abstract translation: 增稠的指甲油 - 除漆组合物具有光滑的，基本上非粒状的稠度。 组合物对指甲和脚趾周围的皮肤基本上是无刺激性的和不敏感的。 干燥后，除漆组合物的残留物是水溶性的。 该组合物包含51重量％至99.9重量％的丁内酯有机溶剂和/或丙二醇衍生物溶剂和0.1重量％至5重量％的至少一种水溶性增稠剂，其能够在不存在中和 并且其存在的量有效地在20℃下产生250-10,000cp的绝对运动粘度。

公开(公告)号：US06503545B1

公开(公告)日：2003-01-07

申请号：US09678180

申请日：2000-09-28

Applicant: Daniel Perlman ,  Kenneth C. Hayes

Inventor： Daniel Perlman ,  Kenneth C. Hayes

IPC: A23L1302

CPC classification number: A23C9/158 ,  A23C11/04 ,  A23C19/0921 ,  A23L33/15 ,  A23V2002/00 ,  A23V2250/5424 ,  A23V2250/712

Abstract: A milk product providing an individual at least 31 IU (International Units) of vitamin E per serving, or an ingestible blend of at least one mammalian milk protein or fragment thereof, and vitamin E or other fat-soluble micronutrient or pharmacological agent is described. The vitamin E is uniformly microdispersed throughout the milk product, and ingestion of at least 100 IU of vitamin E per day in the product is sufficient to cause the fasting plasma vitamin E/cholesterol ratio in human subjects to be elevated at least 50% above the basal fasting level of vitamin E measured in the same subjects consuming no vitamin E dietary supplements. A method for elevating the plasma vitamin E level at least 50% in human subjects is also described. The method includes ingesting a milk product as described. A method for increasing the bioavailability of an orally administered fat-soluble micronutrient or pharmaceutical agent is also described. The method includes providing a microdispersed mixture of at least one fat-soluble micronutrient or pharmaceutical agent, and at least one mammalian milk protein or fragment thereof, in which the weight ratio of the milk protein to the micronutrient or pharmaceutical agent is between 1:1 and 1000:1.

Abstract translation: 描述了提供个体至少31IU（国际单位）每份维生素E或至少一种哺乳动物乳蛋白或其片段的可摄入共混物和维生素E或其它脂溶性微量营养素或药理学物质的乳制品。 维生素E在整个乳制品中均匀地微分散，每天至少摄入100 IU维生素E足以使人体受试者的空腹血浆维生素E /胆固醇比例升高至高于 维生素E的基础禁食水平在同一受试者中测量不消耗维生素E膳食补充剂。 还描述了在人受试者中提高血浆维生素E水平至少50％的方法。 该方法包括如上所述摄取牛奶制品。 还描述了用于增加口服给药的脂溶性微量营养素或药剂的生物利用度的方法。 该方法包括提供至少一种脂溶性微量营养素或药剂的微分散混合物和至少一种哺乳动物乳蛋白或其片段，其中乳蛋白与微量营养素或药剂的重量比为1:1 和1000：1。

公开(公告)号：US6033736A

公开(公告)日：2000-03-07

申请号：US106931

申请日：1998-06-29

Applicant: Daniel Perlman ,  Robert Black

Inventor： Daniel Perlman ,  Robert Black

IPC: C09D5/00 ,  C09D191/06 ,  C09D191/08 ,  B05D1/38

CPC classification number: C09D191/06 ,  C09D191/08 ,  C09D5/002

Abstract: A method of improving the adhesion and durability of both new paint coatings, and older cracked or peeling paint coatings on an architectural surface is described. An aqueous wax emulsion (AWE) which, upon drying, forms an aqueous wax emulsion coating (AWEC), is adherent to an architectural surface as well as to new and older paint coatings. The AWEC is furthermore waterproof, and is hyper-permeable to water vapor, thereby preventing moisture-related bubbling and peeling of the new and older paint coatings.

Abstract translation: 描述了改进两种新涂料涂料的粘合性和耐久性的方法，以及在建筑表面上的较旧的破裂或剥落的涂料涂料。 在干燥后形成水性蜡乳液涂层（AWEC）的水性蜡乳液（AWE）粘附到建筑表面以及新的和较旧的涂料涂料。 AWEC进一步防水，并且对水蒸汽是高渗透性的，从而防止新旧涂料的水分相关的起泡和剥离。

公开(公告)号：US5941589A

公开(公告)日：1999-08-24

申请号：US844286

申请日：1997-04-18

Applicant: Daniel Perlman ,  Jack O'Donnell ,  Jim DeTemple

Inventor： Daniel Perlman ,  Jack O'Donnell ,  Jim DeTemple

IPC: B60R11/00 ,  B60R9/02

CPC classification number: B60R11/00

Abstract: A chock block holder for installation in a vehicle body includes a hollow, generally triangular body having a central axis and having first and second ends, the first end being closed, and the second end being open, and a peripheral flange on the first end, the peripheral flange lying in a plane not perpendicular to the central axis. A method of storing a chock block in a vehicle body having a vertical side wall, includes the steps of placing a chock block holder in the form of a hollow, generally triangular body having a central axis, and first and second ends, the first end being closed, and the second end being open and having a peripheral flange on the first end, the peripheral flange lying in a plane not perpendicular to the central axis, in an opening in the side wall so that the flange is in contact with the side wall and the first end is downward from the second end; and fastening the flange to the side wall.

Abstract translation: 用于安装在车身中的止动块支架包括中空的大​​致三角形的主体，其具有中心轴线并具有第一和第二端部，第一端部被封闭，第二端部敞开，第一端部的周边凸缘， 周边凸缘位于不垂直于中心轴线的平面内。 一种在具有垂直侧壁的车身中存储轴承座的方法包括以下步骤：将具有中心轴线的中空大致三角形主体的轴承座保持件放置在第一端和第二端上， 并且第二端开放，并且在第一端上具有周边凸缘，周边凸缘位于不垂直于中心轴线的平面中，在侧壁的开口中，使得凸缘与侧面接触 第一端从第二端向下; 并将凸缘紧固到侧壁上。

公开(公告)号：US5843497A

公开(公告)日：1998-12-01

申请号：US626461

申请日：1996-04-02

Applicant: Kalyana Sundram ,  Daniel Perlman ,  Kenneth C. Hayes

Inventor： Kalyana Sundram ,  Daniel Perlman ,  Kenneth C. Hayes

IPC: A21D2/14 ,  A21D13/08 ,  A23C19/093 ,  A23D9/00 ,  A23L1/24 ,  A23L1/30 ,  A61K31/23 ,  A61K31/231 ,  A61K31/232

CPC classification number: A23D9/00 ,  A21D13/08 ,  A21D2/145 ,  A23C19/093 ,  A23L27/60 ,  A23L33/12 ,  A61K31/23 ,  A61K31/231 ,  A61K31/232

Abstract: A method of increasing the HDL concentration and the HDL/LDL concentration ratio in human serum by providing a balance between a sufficient and required proportion of cholesterol-free saturated fatty acids in the daily dietary fat of the human and a sufficient and required, but not excessive, proportion of polyunsaturated fatty acids comprising linoleic acid in dietary fat, while the remaining proportion of fatty acids and energy from the dietary fat is provided by monounsaturated fatty acids comprising oleic acid. The saturated fatty acids must constitute between 20% and 40% by weight of the daily dietary fat based upon dietary fat accounting for 30% of the total dietary energy consumption, and linoleic acid must constitute between 15% and 40% by weight of dietary fat. In this way, the required proportional intake of polyunsaturated fatty acids enhances the formation of HDL from VLDL and/or decreases the clearance of HDL, while an excessive proportional intake of polyunsaturated fatty acids and monounsaturated fatty acids is avoided to assure a sufficient dietary availability of saturated fatty acids which are required for sufficient VLDL synthesis and HDL production.

Abstract translation: 通过在人的日常饮食脂肪中足够和所需比例的不含胆固醇的饱和脂肪酸之间提供足够的和必需的而不是增加HDL浓度和HDL / LDL浓度比的方法，而不是 过量的，含有亚油酸的多不饱和脂肪酸在饮食脂肪中的比例，而来自膳食脂肪的脂肪酸和能量的剩余比例由包含油酸的单不饱和脂肪酸提供。 基于膳食脂肪占饱和膳食能量的30％，饱和脂肪酸必须占日粮的20％至40％，而亚油酸必须占膳食脂肪的15％至40％ 。 以这种方式，所需的多不饱和脂肪酸的比例摄入可增强VLDL的HDL形成和/或降低HDL的清除率，同时避免多不饱和脂肪酸和单不饱和脂肪酸的过量比例摄入，以确保足够的膳食可用性 足够的VLDL合成和HDL生产所需的饱和脂肪酸。

公开(公告)号：US5578334A

公开(公告)日：1996-11-26

申请号：US418641

申请日：1995-04-07

Applicant: Kalyana Sundram ,  Daniel Perlman ,  Kenneth C. Hayes

Inventor： Kalyana Sundram ,  Daniel Perlman ,  Kenneth C. Hayes

IPC: A21D2/14 ,  A21D13/08 ,  A23C19/093 ,  A23D9/00 ,  A23L1/24 ,  A23L1/30 ,  A61K31/23 ,  A61K31/231 ,  A61K31/232

CPC classification number: A23D9/00 ,  A21D13/08 ,  A21D2/145 ,  A23C19/093 ,  A23L27/60 ,  A23L33/12 ,  A61K31/23 ,  A61K31/231 ,  A61K31/232

Abstract: A method of increasing the HDL concentration and the HDL/LDL concentration ratio in human serum by providing a balance between a sufficient and required proportion of cholesterol-free saturated fatty acids in the daily dietary fat of the human and a sufficient and required, but not excessive, proportion of polyunsaturated fatty acids comprising linoleic acid in dietary fat, while the remaining proportion of fatty acids and energy from the dietary fat is provided by monounsaturated fatty acids comprising oleic acid. The saturated fatty acids must constitute between 20% and 40% by weight of the daily dietary fat based upon dietary fat accounting for 30% of the total dietary energy consumption, and linoleic acid must constitute between 15% and 40% by weight of dietary fat. In this way, the required proportional intake of polyunsaturated fatty acids enhances the formation of HDL from VLDL and/or decreases the clearance of HDL, while an excessive proportional intake of polyunsaturated fatty acids and monounsaturated fatty acids is avoided to assure a sufficient dietary availability of saturated fatty acids which are required for sufficient VLDL synthesis and HDL production.

Abstract translation: 通过在人的日常饮食脂肪中足够和所需比例的不含胆固醇的饱和脂肪酸之间提供足够的和必需的而不是增加HDL浓度和HDL / LDL浓度比的方法，而不是 过量的，含有亚油酸的多不饱和脂肪酸在饮食脂肪中的比例，而来自膳食脂肪的脂肪酸和能量的剩余比例由包含油酸的单不饱和脂肪酸提供。 基于膳食脂肪占饱和膳食能量的30％，饱和脂肪酸必须占日粮的20％至40％，而亚油酸必须占膳食脂肪的15％至40％ 。 以这种方式，所需的多不饱和脂肪酸的比例摄入可增强VLDL的HDL形成和/或降低HDL的清除率，同时避免多不饱和脂肪酸和单不饱和脂肪酸的过量比例摄入，以确保足够的膳食可用性 足够的VLDL合成和HDL生产所需的饱和脂肪酸。

公开(公告)号：US5230832A

公开(公告)日：1993-07-27

申请号：US645203

申请日：1991-01-24

Applicant: Daniel Perlman

Inventor： Daniel Perlman

IPC: B01D57/02 ,  B01J13/00 ,  C08B37/00 ,  C08J3/28 ,  C08L5/12 ,  C08L5/14 ,  C12Q1/68 ,  G01N27/447

CPC classification number: G01N27/44747 ,  C08L5/12 ,  C08L5/14 ,  C12Q1/68 ,  Y10S522/911

Abstract: A method for forming an agarose electrophoretic gel by addition of gamma-irradiated clarified galactomannan (.gamma.CGM) to optically clarify the gel and improve the electrophoretic fractionation and resolution of oligonucleotides differing in molecular weight. The gel includes agarose, an electrophoretic buffer for nucleic acids, and a CGM vegetable gum subjected to between 0.1 and 4.0 megarads of ionizing gamma radiation.

Abstract translation: 通过加入γ-辐射的澄清半乳甘露聚糖（γGMM）形成琼脂糖电泳凝胶的光学澄清凝胶并改善不同分子量的寡核苷酸的电泳分级和分辨率的方法。 凝胶包括琼脂糖，用于核酸的电泳缓冲液和经0.1至4.0兆拉德的电离γ辐射的CGM植物胶。

公开(公告)号：US5225165A

公开(公告)日：1993-07-06

申请号：US883420

申请日：1992-05-11

Applicant: Daniel Perlman

Inventor： Daniel Perlman

IPC: B04B5/02 ,  B01L3/14 ,  B65D35/42 ,  B65D35/44 ,  G01N1/10

CPC classification number: B01L3/5021 ,  B01L3/50825 ,  B01L2300/043 ,  Y10S206/815 ,  Y10S436/81

Abstract: A microcentrifuge tube or other thermoplastic sample container having a round opening and a frictionally seated sealing lid, the lid having a size and shape to cover the perimeter of the tube opening and maintain the inside of the tube free of any contaminant. The lid viewed on an upright closed container has a downwardly extending annular portion shaped to sealing fit inside the opening, the lid further having an integral upwardly projecting lid extension configured and arranged on top of the lid to facilitate aseptic opening, grasping and identification-labeling of the container. The location, angle and size of the lid extension allow mechanical pressure to be used on top of the lid, rather than beneath the lid, to open the container. The improved apparatus and method for opening the container functions to prevent sample contamination which could otherwise occur when a fingernail or other container opening instrument is inserted beneath, and contacts some portion(s) of the underside of the lid. The location, size, and surface finish of the lid extension also allow grasping of the microcentrifuge tube after placement in a centrifuge rotor or storage rack, as well as labeling the tube for sample identification and tracking purposes.

Abstract translation: 具有圆形开口和摩擦放置的密封盖的微量离心管或其它热塑性样品容器，该盖具有覆盖管开口的周边的尺寸和形状，并且保持管的内部没有任何污染物。 在立式密闭容器上观察的盖子具有向下延伸的环形部分，其形状适于密封配合在开口内部，盖子还具有构造并布置在盖的顶部上的一体向上突出的盖延伸部，以便于无菌开启，抓取和识别标签 的容器。 盖子延伸部分的位置，角度和尺寸允许机械压力被使用在盖子的顶部，而不是在盖子的下面，以打开容器。 用于打开容器的改进的装置和方法用于防止当手指甲或其他容器打开工具插入到下面并且接触盖的下侧的一些部分时可能发生的样品污染。 盖子延伸部分的位置，尺寸和表面光洁度还可以在放置在离心机转子或储存架中之后抓取微量离心管，并且还可以标注管子以进行样品识别和跟踪。

公开(公告)号：US5051596A

公开(公告)日：1991-09-24

申请号：US548057

申请日：1990-07-05

Applicant: Daniel Perlman

Inventor： Daniel Perlman

IPC: B41M5/10 ,  G03C5/16 ,  G03C11/02 ,  G21K4/00

CPC classification number: G03C11/02 ,  B41M5/10 ,  G03C5/16 ,  G21K4/00 ,  G21K2004/06

Abstract: Marking tape adapted for use in autography, comprising: a substrate having an upper surface, a phosphorescent coating applied to the upper surface, the coating including phosphor powder grains, the grains phosphorescing with light at a wavelength between 400 and 600 nm upon exposure to UV or visible light, the phosphorescing occurring for a period of at least 5 minutes after the exposure, the concentration of the grains being sufficient to emit sufficient photons and thereby cause X-ray film having a sensitivity of 2000 EI to darken to an optical density of between 0.2 and 3.0.

公开(公告)号：US4933148A

公开(公告)日：1990-06-12

申请号：US228290

申请日：1988-08-04

Applicant: Daniel Perlman

Inventor： Daniel Perlman

IPC: B01L3/02

CPC classification number: B01L3/0275

Abstract: A pipetter barrel extension tube, attachable at its proximal end to any one of a variety of pipetter barrels and at its distal end to standard disposable pipetter tips. The pipetter barrel extension tube serves to extend the length of the barrels and provide sterile access to deep containers while substantially isolating the permanent barrel of the micropipet from damage caused by chemical and radiochemical contamination. One novel design feature of the extension tube is an air channel designed to minimize dead air volume in the extension tube. A removable conical insert plug serves to reduce the air channel volume. Removal of the plug facilitites cleaning and reuse of the extension tube. The device also includes a distal end segment which, when intact, serves as a space-filler to reduce dead air volume in disposable tips for pipetting small volumes. When the segment is removed, the extension tube still attaches to the same disposable tips but allows larger volumes of liquid into these tips as required for larger capacity pipetting devices.

Abstract translation: 移液器筒延伸管，其近端可附接到各种移液器桶中的任何一个并且其远端附接到标准一次性移液器吸头。 移液器筒延伸管用于延长筒的长度，并提供对深度容器的无菌通入，同时基本上隔离微量吸管的永久桶而不受化学和放射化学污染引起的损害。 延伸管的一个新颖设计特征是设计用于最小化延伸管中的死气体积的空气通道。 可移除的锥形插入件用于减少空气通道体积。 拆除插头辅助部件清洁和重新使用延长管。 该装置还包括远端段，当完整的时候，该远端段用作空间填充物，以减少用于吸取小体积的一次性尖端中的死气体积。 当分段被移除时，延伸管仍然附着在相同的一次性尖端上，但是对于较大容量的移液装置所需，允许更大体积的液体进入这些尖端。