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公开(公告)号：US20130053442A1
公开(公告)日：2013-02-28
申请号：US13581074
申请日：2011-02-25
Applicant: Daniel Perlman , Kenneth C. Hayes
Inventor： Daniel Perlman , Kenneth C. Hayes
IPC: A61K31/201 , A61P3/06
CPC classification number: A23D9/007 , A23D7/001 , A23D7/003 , A23D7/0053 , A23D7/0056 , A23D9/00 , A23L33/115 , A23L33/12 , A23V2002/00 , A23V2200/326 , A23V2250/18 , A23V2250/186 , A23V2250/1882 , A23V2250/1942
Abstract: Nutritional fat or oil-based compositions for increasing HDL cholesterol, decreasing total cholesterol (TC), LDL cholesterol and decreasing the LDL/HDL cholesterol ratio in human plasma are described. The compositions can advantageously include at least 10% of myristic acid and/or lauric acid in which at least 3% of said fatty acid composition is myristic acid and at least 3% is lauric acid; in some cases at least 1% by weight myristic acid and/or lauric acid is esterified at the sn-2 position in triglyceride molecules. The compositions also include between 5% and 40% by weight linoleic acid, and typically further include at least 10% by weight monounsaturated fatty acids and between 15% and 55% by weight total saturated fatty acids. The sum of weight percentages for saturated, monounsaturated and polyunsaturated fatty acids equals 100%. In desirable cases, the composition is substantially cholesterol-free. Also described are fat compositions and diets which are adapted to limit increases in blood triglycerides, total cholesterol, LDL, and VLDL, even in the presence of dietary cholesterol.
Abstract translation: 描述了用于增加HDL胆固醇，降低总胆固醇（TC），低密度脂蛋白胆固醇和降低人血浆中LDL / HDL胆固醇比例的营养脂肪或油基组合物。 组合物可以有利地包括至少10％的肉豆蔻酸和/或月桂酸，其中至少3％的所述脂肪酸组合物是肉豆蔻酸，并且至少3％是月桂酸; 在一些情况下，至少1重量％的肉豆蔻酸和/或月桂酸在甘油三酯分子的sn-2位被酯化。 组合物还包括5重量％至40重量％的亚油酸，并且通常还包括至少10重量％的单不饱和脂肪酸和15重量％至55重量％的总饱和脂肪酸。 饱和，单不饱和和多不饱和脂肪酸的重量百分比之和等于100％。 在期望的情况下，组合物基本上不含胆固醇。 还描述了脂肪组合物和饮食，其适于限制血液甘油三酯，总胆固醇，低密度脂蛋白和VLDL的增加，即使在膳食胆固醇的存在下。
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2.发明授权Blends of palm fat and corn oil provide oxidation-resistant shortenings for baking and frying 失效棕榈油和玉米油的混合物可提供抗氧化的烘烤和油炸的起酥油
公开(公告)号：US5874117A
公开(公告)日：1999-02-23
申请号：US755591
申请日：1996-11-25
Applicant: Kalyana Sundram , Daniel Perlman , Kenneth C. Hayes
Inventor： Kalyana Sundram , Daniel Perlman , Kenneth C. Hayes
Abstract: An oxidation-resistant food shortening which includes a blended vegetable fat composition having between 50% and 95% by weight palm fat and between 5% and 50% corn oil. Also, described is a method of increasing the polyunsaturated fatty acid content of a palm fat-containing shortening while minimizing the loss in oxidative stability of the shortening, wherein the palm fat is supplemented with between approximately 5% and 100% by weight corn oil.
Abstract translation: 抗氧化食品缩短，其包括具有50％至95％（重量）的棕榈脂肪和5％至50％的玉米油的混合植物脂肪组合物。 此外，还描述了增加含棕榈油的起酥油的多不饱和脂肪酸含量的方法，同时使起酥油的氧化稳定性降低最小化，其中棕榈脂肪补充有约5％至100％的玉米油。
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公开(公告)号：US5514407A
公开(公告)日：1996-05-07
申请号：US58747
申请日：1993-05-07
Applicant: Daniel Perlman , Kenneth C. Hayes
Inventor： Daniel Perlman , Kenneth C. Hayes
CPC classification number: A21D2/16 , A23D7/001 , A23D9/00 , Y10S426/804 , Y10S514/824
Abstract: Blended cholesterol-reduced animal fat and vegetable oil which are combined in a proportion such that the weight ratio of linoleic acid (18:2) content divided by myristic acid (14:2) content is between 2 and 9 inclusive.In addition, cholesterol-reduced animal fact can be blended with cholesterol-reduced fish oil to stabilize the fish oil against air-oxidation at room temperature.
Abstract translation: 将胆固醇降低的动物脂肪和植物油混合在一起，使得亚油酸（18:2）含量除以肉豆蔻酸（14：2）含量的重量比在2和9之间。 此外，胆固醇降低的动物事实可以与胆固醇降低的鱼油混合，以稳定鱼油，防止室温下的空气氧化。
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公开(公告)号：US08617634B2
公开(公告)日：2013-12-31
申请号：US13060586
申请日：2009-08-25
Applicant: Daniel Perlman , Kenneth C. Hayes
Inventor： Daniel Perlman , Kenneth C. Hayes
IPC: A23D9/00
Abstract: A nutritional fat or oil-based composition for increasing HDL cholesterol, decreasing LDL cholesterol and decreasing the LDL/HDL cholesterol ratio in human plasma is described. The composition can advantageously include at least 1% by weight myristic acid esterified at the sn-2 position in triglyceride molecules, includes between 10% and 40% by weight linoleic acid, and further includes between 30% and 65% by weight oleic acid and between 15% and 40% by weight total saturated fatty acids. The ratio of sn-2 myristic acid to sn-2 palmitic acid is typically greater than 1:1 and the sum of weight percentages for saturated, monounsaturated and polyunsaturated fatty acids equals 100%. In desirable cases, the composition is substantially cholesterol-free.
Abstract translation: 描述了用于增加HDL胆固醇，降低LDL胆固醇和降低人血浆中LDL / HDL胆固醇比例的营养型油脂或组合物。 组合物可以有利地包括在甘油三酯分子中在sn-2位置酯化的至少1重量％的肉豆蔻酸，包括10重量％至40重量％的亚油酸，并且还包含30重量％至65重量％的油酸和 15％至40％（重量）的总饱和脂肪酸。 sn-2肉豆蔻酸与sn-2棕榈酸的比例通常大于1:1，饱和，单不饱和和多不饱和脂肪酸的重量百分比之和等于100％。 在期望的情况下，组合物基本上不含胆固醇。
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公开(公告)号：US20110104326A1
公开(公告)日：2011-05-05
申请号：US12197542
申请日：2008-08-25
Applicant: Daniel Perlman , Kenneth C. Hayes
Inventor： Daniel Perlman , Kenneth C. Hayes
IPC: A23D9/00
Abstract: A nutritional fat or oil-based composition for increasing HDL cholesterol, decreasing LDL cholesterol and decreasing the LDL/HDL cholesterol ratio in human plasma is described. The composition typically includes at least 1% by weight myristic acid esterified at the sn-2 position in triglyceride molecules, includes between 10% and 40% by weight linoleic acid, and further includes between 30% and 65% by weight oleic acid and between 15% and 40% by weight total saturated fatty acids. The ratio of sn-2 myristic acid to sn-2 palmitic acid is typically greater than 1:1 and the sum of weight percentages for saturated, monounsaturated and polyunsaturated fatty acids equals 100%. In desirable cases, the composition is substantially cholesterol-free.
Abstract translation: 描述了用于增加HDL胆固醇，降低LDL胆固醇和降低人血浆中LDL / HDL胆固醇比例的营养型油脂或组合物。 组合物通常包含在甘油三酯分子中在sn-2位置酯化的至少1重量％的肉豆蔻酸，包括10重量％至40重量％的亚油酸，并且还包含30重量％至65重量％的油酸之间，以及 15％和40％（重量）的总饱和脂肪酸。 sn-2肉豆蔻酸与sn-2棕榈酸的比例通常大于1:1，饱和，单不饱和和多不饱和脂肪酸的重量百分比之和等于100％。 在期望的情况下，组合物基本上不含胆固醇。
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Patent Agency Ranking
公开(公告)号：US6156354A
公开(公告)日：2000-12-05
申请号：US325258
申请日：1999-06-03
Applicant: Daniel Perlman , Kenneth C. Hayes
Inventor： Daniel Perlman , Kenneth C. Hayes
CPC classification number: A23C9/158 , A23C11/04 , A23C19/0921 , A23L33/15 , A23V2002/00
Abstract: A milk product including a level of vitamin E per serving of said product which can conveniently provide at least 100 IU of vitamin E per day to an individual ingesting the product. The vitamin E is uniformly microdispersed throughout the product, and ingestion of at least 100 IU of vitamin E per day in the product is sufficient to cause the fasting plasma vitamin E/cholesterol ratio in human subjects to be elevated at least 50% above the basal fasting level of vitamin E measured in the same subjects consuming no vitamin E dietary supplements. A method for elevating the plasma vitamin E level at least 50% in human subjects is also described. The method includes ingesting a milk product as described.
Abstract translation: 一种乳制品，包括每份所述产品的维生素E水平，其可以方便地每天向摄取产品的个体提供至少100IU的维生素E。 维生素E在整个产品中均匀地微分散，并且每天在产品中摄入至少100IU的维生素E足以使人受试者的空腹血浆维生素E /胆固醇比例升高至基础以上至少50％ 维生素E的空腹水平在同一受试者中测量不消耗维生素E膳食补充剂。 还描述了在人受试者中提高血浆维生素E水平至少50％的方法。 该方法包括如上所述摄取牛奶制品。
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公开(公告)号：US5382442A
公开(公告)日：1995-01-17
申请号：US883642
申请日：1992-05-15
Applicant: Daniel Perlman , Kenneth C. Hayes
Inventor： Daniel Perlman , Kenneth C. Hayes
CPC classification number: A21D2/16 , A23D7/001 , A23D9/00 , Y10S426/804 , Y10S514/824
Abstract: Blended cholesterol-reduced animal fat and vegetable oil which are combined in a proportion such that the weight ratio of linoleic acid (18:2) content divided by myristic acid (14:2) content is between 2 and 9 inclusive.In addition, cholesterol-reduced animal fat can be blended with cholesterol-reduced fish oil to stabilize the fish oil against air-oxidation at room temperature.
Abstract translation: 将胆固醇降低的动物脂肪和植物油混合在一起，使得亚油酸（18:2）含量除以肉豆蔻酸（14：2）含量的重量比在2和9之间。 此外，胆固醇降低的动物脂肪可以与胆固醇降低的鱼油混合，以稳定鱼油，防止室温下的空气氧化。
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公开(公告)号：US20120282368A1
公开(公告)日：2012-11-08
申请号：US13100236
申请日：2011-05-03
Applicant: Daniel Perlman , Kenneth C. Hayes , Andrzej Pronczuk , Fadi Chaabo
Inventor： Daniel Perlman , Kenneth C. Hayes , Andrzej Pronczuk , Fadi Chaabo
IPC: A23D7/005 , A23D9/007 , A23C9/152 , A23C11/10 , A23C13/00 , A23C9/123 , A23L1/24 , A23L1/40 , A23L2/38 , A23L1/035 , A23C19/076
CPC classification number: A23D9/013 , A23C9/152 , A23C11/103 , A23C2240/10 , A23D7/0053 , A23D7/011 , A23D9/007 , A23L23/00 , A23L27/60 , A23L29/10 , A23L33/11 , A23V2002/00 , A23V2200/222 , A23V2250/2136
Abstract: The present invention relates to amphiphilic sterol- and fat-based particles, which can be dispersed in liquid foods and beverages such as milk. The compositions provided, when consumed, reduce low-density lipoprotein (LDL) and total plasma cholesterol (TC) levels.
Abstract translation: 本发明涉及可分散在液体食品和饮料如牛奶中的两亲甾醇和脂肪基颗粒。 当消耗时，提供的组合物降低低密度脂蛋白（LDL）和总血浆胆固醇（TC）水平。
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公开(公告)号：US08114461B2
公开(公告)日：2012-02-14
申请号：US12197542
申请日：2008-08-25
Applicant: Daniel Perlman , Kenneth C. Hayes
Inventor： Daniel Perlman , Kenneth C. Hayes
Abstract: A nutritional fat or oil-based composition for increasing HDL cholesterol, decreasing LDL cholesterol and decreasing the LDL/HDL cholesterol ratio in human plasma is described. The composition typically includes at least 1% by weight myristic acid esterified at the sn-2 position in triglyceride molecules, includes between 10% and 40% by weight linoleic acid, and further includes between 30% and 65% by weight oleic acid and between 15% and 40% by weight total saturated fatty acids. The ratio of sn-2 myristic acid to sn-2 palmitic acid is typically greater than 1:1 and the sum of weight percentages for saturated, monounsaturated and polyunsaturated fatty acids equals 100%. In desirable cases, the composition is substantially cholesterol-free.
Abstract translation: 描述了用于增加HDL胆固醇，降低LDL胆固醇和降低人血浆中LDL / HDL胆固醇比例的营养型油脂或组合物。 组合物通常包含在甘油三酯分子中在sn-2位置酯化的至少1重量％的肉豆蔻酸，包括10重量％至40重量％的亚油酸，并且还包含30重量％至65重量％的油酸之间，以及 15％和40％（重量）的总饱和脂肪酸。 sn-2肉豆蔻酸与sn-2棕榈酸的比例通常大于1:1，饱和，单不饱和和多不饱和脂肪酸的重量百分比之和等于100％。 在期望的情况下，组合物基本上不含胆固醇。
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公开(公告)号：US20110166227A1
公开(公告)日：2011-07-07
申请号：US12985441
申请日：2011-01-06
Applicant: Daniel Perlman , Kenneth C. Hayes
Inventor： Daniel Perlman , Kenneth C. Hayes
CPC classification number: A23D7/001 , A23D7/003 , A23D9/00 , A23K20/158 , A23L33/12 , A23V2002/00 , A61K31/20 , A61K31/201 , A61K45/06 , A61K2300/00 , A23V2250/1882 , A23V2200/3262 , A23V2250/186 , A23V2250/1872
Abstract: Nutritional fat or oil-based compositions for increasing HDL cholesterol, decreasing total cholesterol (TC), LDL cholesterol and decreasing the LDL/HDL cholesterol ratio in human plasma are described. The compositions can advantageously include at least 10% of myristic acid and/or lauric acid in which at least 3% of said fatty acid composition is myristic acid and at least 3% is lauric acid; in some cases at least 1% by weight myristic acid and/or lauric acid is esterified at the sn-2 position in triglyceride molecules. The compositions also include between 5% and 40% by weight linoleic acid, and typically further include at least 10% by weight monounsaturated fatty acids and between 15% and 55% by weight total saturated fatty acids. The sum of weight percentages for saturated, monounsaturated and polyunsaturated fatty acids equals 100%. In desirable cases, the composition is substantially cholesterol-free. Also described are fat compositions and diets which are adapted to limit increases in blood triglycerides, total cholesterol, LDL, and VLDL, even in the presence of dietary cholesterol.
Abstract translation: 描述了用于增加HDL胆固醇，降低总胆固醇（TC），低密度脂蛋白胆固醇和降低人血浆中LDL / HDL胆固醇比例的营养脂肪或油基组合物。 组合物可以有利地包括至少10％的肉豆蔻酸和/或月桂酸，其中至少3％的所述脂肪酸组合物是肉豆蔻酸并且至少3％是月桂酸; 在一些情况下，至少1重量％的肉豆蔻酸和/或月桂酸在甘油三酯分子的sn-2位被酯化。 组合物还包括5重量％至40重量％的亚油酸，并且通常还包括至少10重量％的单不饱和脂肪酸和15重量％至55重量％的总饱和脂肪酸。 饱和，单不饱和和多不饱和脂肪酸的重量百分比之和等于100％。 在期望的情况下，组合物基本上不含胆固醇。 还描述了脂肪组合物和饮食，其适于限制血液甘油三酯，总胆固醇，低密度脂蛋白和VLDL的增加，即使在膳食胆固醇的存在下。
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