公开(公告)号：WO2012075008A2

公开(公告)日：2012-06-07

申请号：PCT/US2011/062398

申请日：2011-11-29

Applicant: HOWARD UNIVERSITY ,  KIM, Charles J.

Inventor： KIM, Charles J.

IPC: H05B37/02 ,  F21S2/00 ,  F21V23/00

CPC classification number: F21V23/0457 ,  F21S2/005 ,  F21W2131/406 ,  F21Y2105/10 ,  F21Y2113/13 ,  F21Y2115/10 ,  H05B33/0851 ,  H05B33/0869 ,  H05B37/029

Abstract: A lighting element is disposed in an array of lighting elements. At the lighting element, a lighting status of at least one neighboring lighting element is sensed. Independent of any other lighting element, a lighting adjustment for the lighting element by applying the sensed lighting status to a predetermined rule is determined. The lighting adjustment is applied to the lighting element to adjust an illumination of the lighting element.

Abstract translation: 照明元件设置在照明元件的阵列中。 在照明元件处，感测至少一个相邻照明元件的照明状态。 独立于任何其他照明元件，确定通过将感测的照明状态应用于预定规则的照明元件的照明调整。 照明调节被应用于照明元件以调节照明元件的照明。

公开(公告)号：WO2012071452A2

公开(公告)日：2012-05-31

申请号：PCT/US2011/061917

申请日：2011-11-22

Applicant: HOWARD UNIVERSITY ,  AKALA, Emmanuel Oyekanmi ,  OKUNOLA, Oluyomi Modupe

Inventor： AKALA, Emmanuel Oyekanmi ,  OKUNOLA, Oluyomi Modupe

IPC: C08F265/06 ,  C08F220/10 ,  C08F220/18 ,  C08F283/06 ,  A61K47/30

CPC classification number: A61K9/1641 ,  A61K9/5146 ,  A61K31/135 ,  A61K31/337 ,  A61K31/704 ,  C08F8/00 ,  C08F8/30 ,  C08F220/68 ,  C08F290/062 ,  Y10T428/2982 ,  C08F120/14 ,  C08F220/18 ,  C08F222/00

Abstract: The present invention is directed to a crosslinked or non-croslinked polymer particle, wherein the crosslinked polymer particle comprises a copolymer of poly (alklyene glycol-graft-acrylate) that is crosslinked by at least one hydrolysable monmer or crosslinking agent. The present invention is also directed to a polymer particle comprising a crosslinked polymer particle that is a product of starting materials comprising (a) a hydrophilic monomer, (b) a hydrophobic monomer, and (c) a hydrolysable crosslinking agent (the crosslinking agent may be absent in the case of non-crosslinked particles). The present invention is still further directed to a polymer particle comprising a crosslinked copolymer, where the crosslinked copolymer includes structures represented by Formulas (I), (II), and (III), as defined in the specification. Other embodiments of the present invention also include methods of manufacturing polymer particles.

Abstract translation: 本发明涉及交联或未交联的聚合物颗粒，其中交联聚合物颗粒包含由至少一种可水解单体交联的聚（亚烷基二醇 - 接枝 - 丙烯酸酯）的共聚物 或交联剂。 本发明还涉及包含交联聚合物颗粒的聚合物颗粒，所述交联聚合物颗粒是包含（a）亲水单体，（b）疏水单体和（c）可水解交联剂（所述交联剂可以是 在未交联颗粒的情况下不存在）。 本发明还涉及包含交联共聚物的聚合物颗粒，其中交联共聚物包括如说明书中所定义的由式（I），（II）和（III）表示的结构。 本发明的其他实施方式还包括制造聚合物颗粒的方法。

公开(公告)号：WO2011115986A3

公开(公告)日：2011-09-22

申请号：PCT/US2011/028511

申请日：2011-03-15

Applicant: HOWARD UNIVERSITY ,  BURGE, Legand L., III

Inventor： BURGE, Legand L., III

IPC: G06F15/16 ,  G06F9/06

Abstract: A context of a mobile device is determined. A context preference of a user associated with the mobile device is determined. The context of the mobile device and the user context preference is transmitted to another node and responsively returned data is received. Available free space in the mobile device is determined. All data whose timestamp is within a predetermined threshold is cached. The data is cached in at least a portion of the free space.

公开(公告)号：WO1993017678A1

公开(公告)日：1993-09-16

申请号：PCT/US1993001924

申请日：1993-03-02

Applicant: HOWARD UNIVERSITY

Inventor： HOWARD UNIVERSITY ,  SCOTT, Kenneth, R. ,  NICHOLSON, Jesse, M. ,  EDAFIOGHO, Ivan, O.

IPC: A61K31/24

CPC classification number: C07D295/30 ,  C07C45/512 ,  C07C225/20 ,  C07C229/48 ,  C07C237/24 ,  C07C243/22 ,  C07C2601/16 ,  C07C49/403

Abstract: Enaminones which display anticonvulsant activity having formula (I) wherein R is from the group consisting of COOCH3 and COOC2H5; R is from the group consisting of H and CH3; R is from the group consisting of H and CH3; and R is from the group consisting of heterocyclic radicals, substituted heterocyclic radicals, benzyls, substitued benzyls, disubstituted benzyls, hydrazinos, substituted hydrazinos, disubstituted hydrazinos, disubstituted phenyls and trisubstituted phenyls, wherein the substituted species are second radicals having positive lipophilicity.

Abstract translation: 显示具有式（I）的抗惊厥活性的呼吸虫，其中R是由COOCH 3和COOC 2 H 5组成的组; R 1来自H和CH 3; R 2来自H和CH 3; R 3为杂环基，取代的杂环基，苄基，取代的苄基，二取代的苄基，肼基，取代的肼基，二取代的肼基，二取代的苯基和三取代的苯基，其中取代的物质是具有正性亲油性的第二基团 。

公开(公告)号：WO2023004007A1

公开(公告)日：2023-01-26

申请号：PCT/US2022/037820

申请日：2022-07-21

Applicant: HOWARD UNIVERSITY ,  WADE, Mamadou Ibra

Inventor： WADE, Mamadou Ibra

IPC: H04L9/14 ,  H04L9/30 ,  H04L9/40

Abstract: Systems, methods and apparatus for secure encryption and decryption of a file may be provided which may include generating, by a first processor, a plurality of encryption isokeys, wherein the plurality of encryption isokeys include a first public isokey, a second public isokey, and a private isounit; and encrypting, by the first processor, ciphertext associated with a message based on the plurality of encryption isokeys. The approach may also include receiving, by a second processor, the ciphertext associated with the message; generating, by the second processor, a plurality of decryption isokeys, wherein the plurality of decryption isokeys include the private isounit, a private decryption isokey, and the first public isokey; and decrypting, by the second processor, the message associated with the ciphertext based on the plurality of decryption isokeys.

公开(公告)号：WO2021252745A1

公开(公告)日：2021-12-16

申请号：PCT/US2021/036782

申请日：2021-06-10

Applicant: HOWARD UNIVERSITY

Inventor： TIZABI, Yousef ,  COPELAND, Robert L.

IPC: A61P25/16 ,  A61M15/00 ,  A61K31/465 ,  A61K9/0043 ,  A61K9/007 ,  A61K9/0075

Abstract: A method for treating or mitigating Parkinson's disease (PD) symptoms or progression, including administering an effective amount of nicotine to a subject in need thereof, via inhalation using a nicotine inhaler or via nasal spray using a nicotine nasal spray. Significant dose-dependent improvement of all symptoms by nicotine inhaler or nicotine nasal spray is expected. A novel treatment in PD is thus provided.

公开(公告)号：WO2018102722A1

公开(公告)日：2018-06-07

申请号：PCT/US2017/064275

申请日：2017-12-01

Applicant: HOWARD UNIVERSITY ,  CHANDRAN, Preethi

Inventor： CHANDRAN, Preethi

IPC: A61K31/702 ,  A61K31/738 ,  C07H3/04

Abstract: Methods and compositions are provided for preventing and/or treating infection by disrupting interactions at or near the surface of mannosylated pathogens or other pathogens exhibiting carbohydrate-carbohydrate self-interaction, thus enhancing the immune system's ability to recognize and destroy such pathogens. In some forms, carrier molecules are provided to delivering polymers or other molecules capable of disrupting intra-cellular interaction and/or self-interaction of surface markers on cells.

公开(公告)号：WO2016085861A1

公开(公告)日：2016-06-02

申请号：PCT/US2015/062159

申请日：2015-11-23

Applicant: HOWARD UNIVERSITY

Inventor： KIM, Charles J.

IPC: G06F21/50 ,  G06F11/20

CPC classification number: G06F21/567 ,  G05B9/02 ,  G06F11/1487 ,  G06F11/1641 ,  G06F11/165 ,  G06F21/552

Abstract: A redundant and diverse secondary control system mirrors a primary control system but has some fundamental structural difference as compared to the primary control system to prevent a spread of a security breach from the primary control system to the secondary control system. The secondary control system may operate on different hardware built on different software written with different programming language as compared to the primary control system while performing the same function as that of the primary system. By hardware coding the algorithm to produce actuation signals, software based viruses and worms cannot interfere with the secondary control system's operation. A monitor device receives actuation signals from both the primary and secondary controls signals to determine whether an error occurred and to provide correct actuation signals to the controlled system.

Abstract translation: 冗余和多样化的二级控制系统反映了主控制系统，但与主控制系统相比具有一些基本的结构差异，以防止安全漏洞从主控制系统扩展到二级控制系统。 与主控制系统相比，辅助控制系统可以在不同的硬件上运行，该不同的硬件基于用不同的编程语言编写的不同的软件，同时执行与主系统相同的功能。 通过硬件编码该算法来产生致动信号，基于软件的病毒和蠕虫不能干扰二次控制系统的操作。 监视器装置从主控制信号和次控制信号接收致动信号，以确定是否发生错误并向受控系统提供正确的致动信号。

公开(公告)号：WO2015050596A3

公开(公告)日：2015-04-09

申请号：PCT/US2014/042562

申请日：2014-06-16

Applicant: HOWARD UNIVERSITY

Inventor： ANDERSON, John ,  NDOYE, Mandoye ,  ODE, Oludotun ,  OGWORONJO, Henry Chidozie

IPC: G06T7/20 ,  F41H11/136

Abstract: The mathematical majorize-minimize principle is applied in various ways to process the image data to provide a more reliable image from the backscatter data using a reduced amount of memory and processing resources. A processing device processes the data set by creating an estimated image value for each voxel in the image by iteratively deriving the estimated image value through application of a majorize-minimize principle to solve a maximum a posteriori (MAP) estimation problem associated with a mathematical model of image data from the data. A prior probability density function for the unknown reflection coefficients is used to apply an assumption that a majority of the reflection coefficients are small. The described prior probability density functions promote sparse solutions automatically estimated from the observed data.

公开(公告)号：WO2014130566A1

公开(公告)日：2014-08-28

申请号：PCT/US2014/017185

申请日：2014-02-19

Applicant: HOWARD UNIVERSITY

Inventor： ANDERSON, John M. M. ,  NDOYE, Mandoye

IPC: A61B6/03

CPC classification number: G06T15/08 ,  G01S7/046 ,  G01S7/295 ,  G01S13/003 ,  G01S13/885 ,  G01S13/90

Abstract: A majorize-minimize (MM) mathematical principle is applied to least squares regularization estimation problems to effect efficient processing of image data sets to provide good quality images. In a ground penetrating radar application, these approaches can reduce processing time and memory use by accounting for a symmetric nature of a given radar pulse, accounting for similar discrete time delays between transmission of a given radar pulse and reception of reflections from the given radar pulse, and accounting for a short duration of the given radar pulse.

Abstract translation: 主要最小化（MM）数学原理被应用于最小二乘法正则化估计问题，以实现图像数据集的有效处理，以提供高质量的图像。 在地面穿透雷达应用中，这些方法可以通过考虑给定雷达脉冲的对称性来减少处理时间和存储器使用，考虑给定雷达脉冲的传输和从给定的雷达脉冲接收反射之间的类似的离散时间延迟 ，并且考虑给定雷达脉冲的短时间。