公开(公告)号：DK1965816T3

公开(公告)日：2017-06-26

申请号：DK06848618

申请日：2006-12-14

Applicant: OXTHERA INTELLECTUAL PROPERTY AB

Inventor： SIDHU HARMEET ,  KAUL POONAM

IPC: A61K9/19 ,  A23L33/135 ,  A61K9/16 ,  A61K9/48 ,  A61K35/74 ,  A61K47/26 ,  A61K47/36 ,  A61K47/46

公开(公告)号：PT1965816T

公开(公告)日：2017-06-23

申请号：PT06848618

申请日：2006-12-14

Applicant: OXTHERA INTELLECTUAL PROPERTY AB

Inventor： HARMEET SIDHU ,  POONAM KAUL

IPC: A61K9/19 ,  A23L33/135 ,  A61K9/16 ,  A61K9/48 ,  A61K35/74 ,  A61K47/10 ,  A61K47/18 ,  A61K47/26 ,  A61K47/36 ,  A61K47/46

公开(公告)号：PL1771201T3

公开(公告)日：2015-01-30

申请号：PL05786347

申请日：2005-06-15

Applicant: OXTHERA INTELLECTUAL PROPERTY AB

Inventor： SIDHU HARMEET

IPC: A01N37/18 ,  A61K38/00 ,  A61K38/28 ,  A61K38/44 ,  A61K38/45 ,  A61K38/51 ,  A61K38/54

公开(公告)号：PT1771201E

公开(公告)日：2014-11-06

申请号：PT05786347

申请日：2005-06-15

Applicant: OXTHERA INTELLECTUAL PROPERTY AB

Inventor： SIDHU HARMEET

IPC: A01N37/18 ,  A61K38/00 ,  A61K38/28 ,  A61K38/44 ,  A61K38/45 ,  A61K38/51 ,  A61K38/54

公开(公告)号：DK1771201T3

公开(公告)日：2014-11-03

申请号：DK05786347

申请日：2005-06-15

Applicant: OXTHERA INTELLECTUAL PROPERTY AB

Inventor： SIDHU HARMEET

IPC: A01N37/18 ,  A61K38/00 ,  A61K38/28 ,  A61K38/44 ,  A61K38/45 ,  A61K38/51 ,  A61K38/54

公开(公告)号：SI1962873T1

公开(公告)日：2013-10-30

申请号：SI200531760

申请日：2005-12-14

Applicant: OXTHERA INTELLECTUAL PROPERTY AB

Inventor： KAUL POONAM

IPC: A01N63/00 ,  A23L1/00 ,  A61K9/00 ,  A61K35/00 ,  A61K35/74

公开(公告)号：AU2006326016B2

公开(公告)日：2013-10-10

申请号：AU2006326016

申请日：2006-12-14

Applicant: OXTHERA INTELLECTUAL PROPERTY AB

Inventor： SIDHU HARMEET ,  KAUL POONAM

IPC: A01N63/00 ,  A61K35/74

Abstract: The present invention comprises methods and compositions for the reduction of oxalate in humans, animals and plants. For example, the invention provides methods and compositions for the delivery of one or more oxalate-reducing pharmaceutical compositions to the intestinal tracts of persons and animals. The methods and compositions can be used in treating and preventing oxalate-related conditions. A composition of the invention comprises an oral delivery vehicle comprising an oxalate degrading bacteria, one or more cryopreserving agents and one or more excipients. A composition of the invention is enteric coated and has a suitable shelf-life and acceptable properties to avoid negative impact from gastric fluid when it is orally administered.

公开(公告)号：CA2767039A1

公开(公告)日：2011-01-06

申请号：CA2767039

申请日：2010-07-01

Applicant: OXTHERA INTELLECTUAL PROPERTY AB

Inventor： SIDHU HARMEET ,  LI QINGSHAN ,  COWLEY AARON BLAKE ,  GOELANDER CAROL-GUSTAF

IPC: C12N9/02 ,  A61K38/44 ,  A61K38/45 ,  A61K38/51 ,  C12N9/10 ,  C12N9/88 ,  C12P21/02

Abstract: The present invention comprises methods and compositions for the reduction of oxalate in humans, and methods for the purification and isolation of recombinant oxalate reducing enzyme proteins. The invention provides methods and compositions for the delivery of oxalate-reducing enzymes in particle compositions. The compositions of the present invention are suitable in methods of treatment or prevention of oxalate-related conditions.

公开(公告)号：EP3865148A1

公开(公告)日：2021-08-18

申请号：EP21165678.0

申请日：2014-07-03

Applicant: OxThera Intellectual Property AB

Inventor： LINDNER, Elisabeth ,  COWLEY, Helena ,  COWLEY, Aaron ,  ÅKERMAN, Maria

IPC: A61K38/16 ,  A61K35/74 ,  A61P3/00 ,  A61P3/10

Abstract: The present invention relates to a secretagogue compound derived from oxalate degrading bacteria, for use in the treatment of an oxalate related disease and/or oxalate related imbalance in a subject, wherein the administration of the secretagogue results in a reduction of urinary oxalate and/or plasma oxalate in the subject. The invention further relates to a pharmaceutical composition comprising such a secretagogue compound, a method for treating a subject suffering from an oxalate related disease, and to a method for preparing a secretagogue.

公开(公告)号：EP2270138A1

公开(公告)日：2011-01-05

申请号：EP09164430.2

申请日：2009-07-02

Applicant: OxThera Intellectual Property AB

Inventor： Cowley, Aaron Blake ,  Gölander, Carl-Gustaf ,  Li, Qingshan ,  Sidhu, Harmeet

IPC: C12N9/02 ,  C12N9/10 ,  C12N9/88 ,  A61K38/44 ,  A61K38/45 ,  A61K38/51 ,  C12P21/02

CPC classification number: C12N9/13 ,  A61K9/1623 ,  A61K9/1635 ,  A61K38/00 ,  C12N9/0008 ,  C12N9/88 ,  C12Y102/03004 ,  C12Y208/03016 ,  C12Y401/01002 ,  C12Y401/01008

Abstract: The present invention comprises methods and compositions for the reduction of oxalate in humans, and methods for the purification and isolation of recombinant oxalate reducing enzyme proteins. The invention provides methods and compositions for the delivery of oxalate-reducing enzymes in particle compositions. The compositions of the present invention are suitable in methods of treatment or prevention of oxalate-related conditions.

Abstract translation: 本发明包括用于重组草酸盐的纯化和分离减少酶蛋白质的方法和组合物的草酸盐在人体中的减少，和方法。 本发明提供用于减少草酸盐的酶的颗粒组合物递送方法和组合物。 本发明的组合物是适用于治疗或预防草酸盐相关疾病的方法。