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    PORE-FORMING AGENTS FOR ORTHOPEDIC CEMENTS
    82.
    发明申请
    PORE-FORMING AGENTS FOR ORTHOPEDIC CEMENTS 审中-公开
    成型剂的成核剂

    公开(公告)号：WO03024316A3

    公开(公告)日：2003-12-31

    申请号：PCT/US0229966

    申请日：2002-09-20

    Applicant: STRYKER CORP ,  DALAL PARESH S ,  LANDERYOU TRACY J ,  TOTH CAROL ANN ,  KULKARNI SHAILESH C

    Inventor： DALAL PARESH S ,  LANDERYOU TRACY J ,  TOTH CAROL ANN ,  KULKARNI SHAILESH C

    IPC: A61L27/00 ,  A01N43/04 ,  A01N63/00 ,  A61B20060101 ,  A61F2/00 ,  A61F13/00 ,  A61L27/12 ,  A61L27/22 ,  A61L27/56 ,  C07K14/47 ,  C08J9/26 ,  C08J9/28

    CPC classification number: A61L27/227 ,  A61L27/12 ,  A61L27/56

    Abstract: A bone precursor composition comprising a cement mixture and a pore-forming agent is provided for bone implant. Preferably, the pore-forming agent has a particle size of 20-500 mu m. More preferably, the proportion of the pore-forming agent is 7-40% (w/w). The composition may further include a bioactive agent, preferably a bone morphogenic protein or nucleic acid encoding BMP encapsulated in the pore-forming agent. The moldability of the composition can be modulated by the addition of a binder. The invention provides a kit and implant device comprising the bone precursor composition. The invention also provides an implantable prosthetic device comprising a prosthetic implant having a surface region and a bone precursor material disposed on the surface region. The kit and devices may further comprise one or more additional components including a bioactive agent and a binder. Methods of inducing bone formation and delivering the bioactive agent are provided.

    Abstract translation: 提供包含水泥混合物和成孔剂的骨前体组合物用于骨植入。 优选地，成孔剂的粒径为20-500μm。 更优选的是，成孔剂的比例为7-40％（w / w）。 组合物还可以包括生物活性剂，优选骨形态发生蛋白或编码包封在成孔剂中的BMP的核酸。 可以通过添加粘合剂来调节组合物的成型性。 本发明提供了包含骨前体组合物的试剂盒和植入装置。 本发明还提供了一种植入式假体装置，其包括具有布置在表面区域上的表面区域和骨骼前体材料的假体植入物。 试剂盒和装置还可以包含一种或多种另外的组分，包括生物活性剂和粘合剂。 提供诱导骨形成和递送生物活性剂的方法。

    HOSPITAL BED HAVING SERIAL COMMUNICATION NETWORK, DIGITAL VOLUME CONTROL, AND EASILY PERSONALIZED HEADWALL INTERFACE
    86.
    发明申请
    HOSPITAL BED HAVING SERIAL COMMUNICATION NETWORK, DIGITAL VOLUME CONTROL, AND EASILY PERSONALIZED HEADWALL INTERFACE 审中-公开
    具有串行通信网络，数字音量控制和易于个性化主机接口的医院床

    公开(公告)号：WO9427544A2

    公开(公告)日：1994-12-08

    申请号：PCT/US9405593

    申请日：1994-05-17

    Applicant: STRYKER CORP

    Inventor： TRAVIS STEPHEN C ,  REED BRADFORD D

    IPC: A61G7/018 ,  A61G7/05

    CPC classification number: A61G7/0507 ,  A61G7/018 ,  A61G7/05 ,  A61G7/0506 ,  A61G7/0524

    Abstract: A hospital bed (10) has a frame (14, 18) carrying a patient support section (19) and a footboard (37), and two siderails (38, 43) are supported on the frame for movement between raised and lowered positions. The siderails and footboard each have an operator interface (76-80, 88-89) which includes push-button switches and LEDs, and a serial communication link (56-57, 63-64) couples each operator interface to a control circuit (51) mounted on the frame. Each operator interface includes multiple circuit boards (76-80, 88-89) which represent respective function groups and which each can be either present or omitted in dependence on whether its function group is needed. One such board (76) can control an auxiliary device separate from the bed, such as an inflatable mattress (29) with an electrically-controlled pressure. The control circuit (51) is coupled to a headwall interface circuit (62), which in turn is coupled through a socket/header arrangement (233) to a headwall cable connector on the bed. By changing the headers (291-292) in the sockets (286-287), the interconnections between the connector and the interface circuit can be customized for particular applications. The interface circuit (62) includes a digital volume control circuit (261-264, 271-279) for controlling the amplitude of an audio signal supplied to loudspeakers (68-69) provided in the siderails.

    Abstract translation: 医院病床（10）具有承载患者支撑部分（19）和脚踏板（37）的框架（14,18），并且两个支撑架（38,43）被支撑在框架上以在升高和降低位置之间移动。 侧板和脚踏板各自具有包括按钮开关和LED的操作者接口（76-80,88-89），并且串行通信链路（56-57,63-64）将每个操作员接口耦合到控制电路（ 51）安装在框架上。 每个操作员接口包括多个电路板（76-80,88-89），其代表相应的功能组，并且每个电路板可以根据其功能组是否需要存在或省略。 一个这样的板（76）可以控制与床分离的辅助装置，例如具有电控压力的可充气床垫（29）。 控制电路（51）耦合到头壁接口电路（62），后台接口电路又通过插座/插座装置（233）耦合到床上的头壁电缆连接器。 通过更改插座（286-287）中的插座（291-292），可以为特定应用定制连接器和接口电路之间的互连。 接口电路（62）包括数字音量控制电路（261-264,271-279），用于控制提供给设置在座架中的扬声器（68-69）的音频信号的幅度。

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