公开(公告)号：KR1020130119078A

公开(公告)日：2013-10-31

申请号：KR1020120041958

申请日：2012-04-23

Applicant: 서울대학교산학협력단

Inventor： 김현만 ,  김현정

IPC: C01B25/32 ,  C01F11/00 ,  C08G63/08

CPC classification number: C01B25/32 ,  A61L27/12 ,  C01P2006/90

Abstract: PURPOSE: A mechanical strength enhancing method of a calcium phosphate supporter by coating a calcium phosphate thin film and a polymeric membrane is provided to improve the mechanical strength of the calcium phosphate supporter which has the low mechanical strength and an internal space. CONSTITUTION: A manufacturing method of a calcium phosphate supporter in which the intensity is improved by having multiple coating of a calcium phosphate thin film and a polymeric membrane comprises the following steps: a step of coating the polymeric membrane which is remained after volatilizing the solvent after contacting the surface of the calcium phosphate supporter with the polymeric solution; a step of coating to the calcium phosphate thin film which is precipitated by making the coating surface of the polymeric membrane react with the supersaturated calcium phosphate ionic solution; a step of repeating the coating of polymeric membrane and the coating of the calcium phosphate thin film. [Reference numerals] (AA) PCL concentration (%); (BB) Ion solution processing time (min); (CC) Repeat (times); (DD) Post heat-processing temperature (°C); (EE) Pressurizing intensity (MPa); (FF) Average; (GG) Standard deviation; (HH) Control group; (II) Test group; (JJ,KK,LL) Room temperture

Abstract translation: 目的：提供通过涂覆磷酸钙薄膜和聚合物膜的磷酸钙载体的机械强度提高方法，以提高机械强度和内部空间低的磷酸钙载体的机械强度。 构成：通过磷酸钙薄膜和聚合物膜的多次涂覆来提高强度的磷酸钙载体的制造方法包括以下步骤：涂覆溶剂挥发后留下的聚合物膜的步骤 使磷酸钙载体的表面与聚合物溶液接触; 通过使聚合物膜的涂布表面与过饱和磷酸钙离子溶液反应而沉淀的磷酸钙薄膜的步骤; 重复聚合物膜的涂覆和磷酸钙薄膜的涂覆的步骤。 （AA）PCL浓度（％） （BB）离子溶液处理时间（min）; （CC）重复（次）; （DD）后加热温度（℃）; （EE）加压强度（MPa）; （FF）平均; （GG）标准偏差; （HH）对照组; （二）试验组; （JJ，KK，LL）室温

公开(公告)号：KR1020110040388A

公开(公告)日：2011-04-20

申请号：KR1020090097626

申请日：2009-10-14

Applicant: 서울대학교산학협력단 ,  대한민국(농촌진흥청장)

Inventor： 박영환 ,  기창석 ,  이민정 ,  김현정 ,  이광길 ,  강석우 ,  권해용 ,  여주홍 ,  조유영

IPC: A61L27/32 ,  A61L27/56 ,  A61L27/36

CPC classification number: A61L27/32 ,  A61F2310/00365 ,  A61L27/3604 ,  A61L27/56 ,  A61L2430/02

Abstract: PURPOSE: A silk/hydroxyapatite complex nanofiber supporter for osteanagenesis is provided to promote a cell growth promotion effect and to remove cytotoxin. CONSTITUTION: A silk/hydroxyapatite complex nanofiber supporter for osteanagenesis constituted as follows. In the nanofiber supporter, hydroxyapatite is coated on the surface thereof and silk nanofiber having the diameter of tens or hundreds nanometers is three-dimensionally arranged. The silk nanofiber maintains the form of a strand of fiber without conglomeration or entanglement thereof.

Abstract translation: 目的：提供用于骨形成的丝/羟基磷灰石复合纳米纤维支持体，以促进细胞生长促进作用和去除细胞毒素。 构成：用于骨形成的丝/羟基磷灰石复合纳米纤维支持体构成如下。 在纳米纤维支持体中，羟基磷灰石涂布在其表面上，并且三维排列具有数十或数百纳米直径的丝纳米纤维。 丝绸纳米纤维保持纤维束的形式，而不会发生聚集或缠结。

公开(公告)号：KR1020140137490A

公开(公告)日：2014-12-03

申请号：KR1020130057718

申请日：2013-05-22

Applicant: 서울대학교산학협력단

Inventor： 김영규 ,  고무현 ,  신나라 ,  김현정

IPC: C07C209/78 ,  C07C211/09 ,  B01J23/44

Abstract: The present invention relates to a method for manufacturing a α,ω-diamine, which is a raw material of a polyimide based thermoplastic elastomer (TPE) by using α,ω-dicarboxylic acid wherein the α,ω-dicarboxylic acid is synthesized from natural oil. The method in the present invention is allowed to manufacture a α,ω-diamine used as a polyimide monomer and manufacture a α,ω-diamine with various carbon numbers. In addition, the method of the present invention is considered as an eco-friendly manner because α,ω-dicarboxylic acid used as an initiating material can be easily manufactured from natural oil.

Abstract translation: 本发明涉及一种通过使用α，ω-二羧酸作为聚酰亚胺类热塑性弹性体（TPE）的原料的α，ω-二胺的制造方法，其中α，ω-二羧酸由天然 油。 本发明的方法可以制造用作聚酰亚胺单体的α，ω-二胺，制造具有各种碳数的α，ω-二胺。 此外，本发明的方法被认为是环保的方式，因为用作起始材料的α，ω-二羧酸可以容易地由天然油制成。