멜라닌 생성 억제 펩티드, 그 제조방법, 및 이를함유하는 피부 외용제 조성물
    81.
    发明公开
    멜라닌 생성 억제 펩티드, 그 제조방법, 및 이를함유하는 피부 외용제 조성물 有权
    造血抑制肽,其制备方法和含有该成分的局部皮肤白化组合物

    公开(公告)号:KR1020030077271A

    公开(公告)日:2003-10-01

    申请号:KR1020020016298

    申请日:2002-03-26

    CPC classification number: C07K5/1016 A61K8/64 A61K38/07 A61Q19/00 A61Q19/02

    Abstract: PURPOSE: Provided is a melanogenesis-suppressing peptide which effectively suppresses the activation of tyrosinase in the melanogenesis cells. A topical skin-whitening composition containing the melanogenesis-suppressing peptide involves excellent skin whitening effect, and effective improvement and prevention of chloasma, freckles, and other melanin pigmentation. CONSTITUTION: The melanogenesis-suppressing peptide is selected from the group consisting of peptides with the amino acid sequences of SEQ ID NO 1-4. A method of manufacturing the melanogenesis-suppressing peptide comprises the steps of preparing chemical peptide random-sequenced mixtures with 76 cases of 4(locations)x19(amino acids); selecting two or three amino acids per the respective peptide locations with enzyme activity inhibitory effect from the peptide mixtures using tyrosinase extracted from mushrooms; synthesizing secondary peptides based on the selected peptide sequences; and testing the whitening effect and the cell stability of the secondary peptides, and finally selecting the peptide with the amino acid sequences of SEQ ID NO 1-4.

    Abstract translation: 目的:提供有效抑制黑素生成细胞中酪氨酸酶活化的黑素生成抑制肽。 含有黑素生成抑制肽的局部皮肤美白组合物具有优异的皮肤美白效果,有效改善和防止黄褐斑,雀斑和其他黑色素色素沉着。 构成:黑素生成抑制肽选自具有SEQ ID NO 1-4的氨基酸序列的肽。 制备黑素生成抑制肽的方法包括以下步骤:制备具有76个4(位置)x19(氨基酸)的76个化学肽随机排序的混合物; 使用从蘑菇提取的酪氨酸酶从肽混合物中选择两个或三个氨基酸,每个肽位置具有酶活性抑制作用; 基于所选择的肽序列合成二级肽; 并测试第二肽的美白效果和细胞稳定性,最后选择具有SEQ ID NO 1-4的氨基酸序列的肽。

    유색콩 추출물을 함유하는 조성물
    86.
    发明公开
    유색콩 추출물을 함유하는 조성물 无效
    包含色素提取物的组合物

    公开(公告)号:KR1020160073950A

    公开(公告)日:2016-06-27

    申请号:KR1020160071842

    申请日:2016-06-09

    CPC classification number: A61K36/48 A23L33/105 A23V2200/30 A23V2200/326

    Abstract: 본발명은유색콩등으로부터추출한유색콩추출물및 그분획물을유효성분으로함유하는항혈전효능조성물에관한것이다. 본발명에의한항혈전조성물은아데노신을포함하고있으며, 혈전형성의원인이되는심장혈관질환, 뇌혈관질환, 동맥경화증, 고혈압, 당뇨등의순환기계질환의치료에매우유용하게이용될수 있다.

    Abstract translation: 本发明涉及抗紫外线组合物,其含有作为活性成分的从有色豆及其部分提取的有色豆提取物。 本发明的抗血栓形成组合物含有腺苷,可用于治疗血栓形成原因的心血管疾病,脑血管疾病,动脉粥样硬化,高血压,糖尿病等循环系统疾病。

    콩 추출물을 포함하는 혈관 조절 조성물
    88.
    发明公开
    콩 추출물을 포함하는 혈관 조절 조성물 审中-实审
    用于包含豆类提取物的血管控制组合物

    公开(公告)号:KR1020130022477A

    公开(公告)日:2013-03-07

    申请号:KR1020110084745

    申请日:2011-08-24

    CPC classification number: A61K36/48 A23V2200/326 A61K2236/333 Y10S514/929

    Abstract: PURPOSE: A composition containing a bean extract is provided to reduce blood pressure through suppression of vasoconstriction. CONSTITUTION: A composition containing a bean extract for controlling blood vessels contains a bean extract which is prepared using 1-70%(v/v) of C1-C5 alcohol or a fraction thereof. C1-C5 alcohol is selected from a group consisting of methanol, ethanol, isopropyl alcohol, n-propyl alcohol, n-butanol, and isobutanol. [Reference numerals] (AA) Blood vessel extraction(%, 90mMK^+); (BB) Control group; (CC) Black soybean; (DD) White soybean

    Abstract translation: 目的:提供含有豆提取物的组合物,以通过抑制血管收缩来降低血压。 构成:含有用于控制血管的豆提取物的组合物含有使用1-70%(v / v)的C1-C5醇或其一部分制备的豆提取物。 C1-C5醇选自甲醇,乙醇,异丙醇,正丙醇,正丁醇和异丁醇组成的组。 (附图标记)(AA)血管提取(%,90mM K +); (BB)对照组; (CC)黑豆; (DD)白豆

    발효차 추출물을 포함하는 지질 수준 감소용 조성물
    89.
    发明公开
    발효차 추출물을 포함하는 지질 수준 감소용 조성물 有权
    含有发酵茶的提取物的组合物用于降低脂质水平

    公开(公告)号:KR1020120064299A

    公开(公告)日:2012-06-19

    申请号:KR1020100125468

    申请日:2010-12-09

    CPC classification number: A61K36/82 A61K36/44 A61K36/48 A61K2236/19 C12P1/04

    Abstract: PURPOSE: A composition containing fermented tea extract is provided to reduce body fat and to prevent or treat obesity and cardiovascular diseases. CONSTITUTION: A composition for reducing body fat level contains fermented tea extract as an active ingredient which is prepared by inoculating strain to tea. A composition for suppressing lipid decomposition contains the fermented tea extract as an active ingredient. The tea includes green tea, white tea, oolong tea, pure tea, black tea, or persimmon leaf tea. The strain includes Bacillus subtilis, Bacillus licheniformis, Bacillus megateriums, Bacillus natto, Bacillus citreus, Bacillus circulans, Bacillus mesentricus, or Bacillus pumilus.

    Abstract translation: 目的:提供含有发酵茶提取物的组合物,以减少体内脂肪,预防或治疗肥胖和心血管疾病。 构成:用于降低体脂肪含量的组合物含有作为活性成分的发酵茶提取物,其通过将菌株接种到茶中而制备。 用于抑制脂质分解的组合物含有发酵茶提取物作为活性成分。 茶包括绿茶,白茶,乌龙茶,纯茶,红茶或柿子茶。 该菌株包括枯草芽孢杆菌,地衣芽孢杆菌,巨大芽孢杆菌,纳豆芽孢杆菌,柠檬酸芽孢杆菌,环状芽孢杆菌,肠杆菌或短小芽孢杆菌。

    데아닌을 함유하는 프롤린 리사이클링 촉진용 피부 외용제또는 미용 식품 조성물
    90.
    发明公开
    데아닌을 함유하는 프롤린 리사이클링 촉진용 피부 외용제또는 미용 식품 조성물 无效
    皮肤外用食品的组合物或用于加速含有亚硫酸盐的精氨酸回收的食品

    公开(公告)号:KR1020090064743A

    公开(公告)日:2009-06-22

    申请号:KR1020070132054

    申请日:2007-12-17

    CPC classification number: A61K8/44 A61Q19/08

    Abstract: A composition of skin external preparation or cosmetic food for promoting proline recycling is provided to promote the expression or activation of prolidase. A composition of skin external preparation for promoting proline recycling comprises a theanine as an active ingredient. The theanine is contains in a ratio of 0.001-10 weight% based on the total weight. A cosmetic food product contains the theanine as an active ingredient. The theanine is contained in a ratio of .1-40 weight% based on the total weight. The composition of skin external preparation or cosmetic food product for promoting proline recycling promotes the synthesis of collagen and prevent skin wrinkle.

    Abstract translation: 提供用于促进脯氨酸回收的皮肤外用制剂或化妆品食品的组合物以促进脯氨酸酶的表达或活化。 用于促进脯氨酸回收的皮肤外用制剂组合物包括茶氨酸作为活性成分。 所述茶氨酸含量相对于总重量为0.001-10重量%。 化妆品食品含有茶氨酸作为活性成分。 茶氨酸的含量占总重量的1-40重量%。 用于促进脯氨酸回收的皮肤外用制剂或化妆品食品的组成促进胶原蛋白的合成并防止皮肤皱纹。

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