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81.发明授权
公开(公告)号：KR101272741B1
公开(公告)日：2013-06-10
申请号：KR1020050098057
申请日：2005-10-18
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 유용성 활성물질을 안정화한 수분산 양이온성 고분자 나노캡슐 및 이의 제조방법, 및 상기 수분산 양이온성 고분자 나노캡슐을 함유하는 화장료 조성물에 관한 것이다. 보다 상세하게는, 본 발명의 수분산 양이온성 고분자 나노캡슐은 (1) 활성물질을 흡착할 수 있는 양이온성 관능기를 갖는 소수성 고분자를 중합하는 단계; 및 (2) 상기 (1)단계의 소수성 고분자 및 유용성 활성성분을 유기용매에 용해시킨 후 교반하면서 수상과 유기상을 혼합시켜 에멀젼을 제조하고, 유기상을 증발시켜 수상에 존재하는 유용성 활성성분을 포집한 나노캡슐을 제조하는 단계;로 유용성 활성성분을 담지한 수분산 양이온성 고분자 나노 캡슐을 제조하며, 상기의 단계로 제조된 양이온성 고분자 나노캡슐은 유용성 활성물질이 고분자입자 내 존재하는 양이온성 그룹에 흡착되어 있으며, 이로 인해 활성물질을 입자 내부의 양이온 그룹과 고분자벽제에 의해 외부자극으로부터 차단하는 이중 안정화시스템으로 우수한 안정화효과를 나타낸다.
수분산 * 나노 캡슐 * 활성물질 * 양이온성 * 모이어티-
公开(公告)号：KR101206200B1
公开(公告)日：2012-11-28
申请号：KR1020100008675
申请日：2010-01-29
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 미백 유효 성분을 안정화한 미백 캡슐 제제 및 이를 함유하는 피부 미백용 화장료 조성물에 관한 것이다. 보다 상세하게는 유동층 코팅기술을 이용하여 인지질 배합물로 구성된 다층 라멜라상을 미백 유효 성분이 존재하는 조건에서 형성시키고, 형성된 라멜라 구조 내부에 존재하는 미백 유효 성분들을 라멜라상이 효과적으로 고정화시킴으로써 열과 산소에 의한 분자구조 변성을 효과적으로 차단할 수 있는 미백 캡슐 제제에 관한 것이다. 또한, 본 발명의 미백 캡슐 제제는 화장료 조성물 내에서도 물과 계면활성제에 의한 미백 캡슐 제제 내의 스웰링(swelling)을 효과적으로 차단하고 미백 캡슐 제제 내 미백성분의 활성을 장기간 유지함으로써 우수한 미백 효과를 나타낸다.
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公开(公告)号：KR101114659B1
公开(公告)日：2012-03-05
申请号：KR1020050097067
申请日：2005-10-14
Applicant: (주)아모레퍼시픽
Abstract: 본발명은생분해성고분자를이용하여 1종이상의유용성(oil-soluble) 활성성분을안정화한나노입자및 이의제조방법에관한것이다. 보다상세하게는, 본발명에의한유용성활성성분을안정화한나노입자는 (1) 유용성활성성분과생분해성고분자를물과섞이는휘발성유기용매에용해시키는단계; (2) 상기용액을물에분산, 교반시킨후, 나노입자를형성하는단계; 및 (3) 상기나노입자용액중 휘발성유기용매를증발을통하여제거하는단계;로제조한다. 상기의단계로제조한나노입자는 2종이상의생분해성고분자를사용하여고분자캡슐화제의농도를동일하게유지시키면서입자크기를자유롭게조절할수 있으며, 아울러유용성활성성분의농도를유지시키면서화장품제형내에결정석출없이안정하게존재하게함으로써제형의안정화를도모할수 있다.
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公开(公告)号：KR1020110088933A
公开(公告)日：2011-08-04
申请号：KR1020100008675
申请日：2010-01-29
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A capsule formulation with stabilized whitening ingredients and cosmetic composition for skin whitening is provided to effectively block swelling of a whitening agent due to water and surfactant. CONSTITUTION: A capsule formulation for whitening with whitening ingredients contains a lipid lamella layer and a polymer layer. The lipid lamella layer exists on a nucleating agent and contains ceramide, phospholipid, and whitening ingredients. The ceramide is natural ceramide or ceramide analogue. The phospholipid is selected from phosphatidyl choline, phosphatidyl serine, phosphatidyl glycerol, and phosphatidic acid. The whitening ingredients is selected from the group consisting of ellagic acid, Rabdosia Rubescens extract, Saxifraga furumiii extract, grape extract, Scutellariae radix extract, and acetyltetrapeptide-11.
Abstract translation: 目的：提供具有稳定的美白成分和用于皮肤美白的化妆品组合物的胶囊制剂，以有效阻止由于水和表面活性剂引起的增白剂的膨胀。 构成：用美白成分增白的胶囊制剂含有脂质层层和聚合物层。 脂质层层存在于成核剂上并含有神经酰胺，磷脂和美白成分。 神经酰胺是天然神经酰胺或神经酰胺类似物。 磷脂选自磷脂酰胆碱，磷脂酰丝氨酸，磷脂酰甘油和磷脂酸。 美白成分选自鞣花酸，茄子提取物，蔷薇提取物，葡萄提取物，黄芩提取物和乙酰四肽-11。
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公开(公告)号：KR1020110060257A
公开(公告)日：2011-06-08
申请号：KR1020090116791
申请日：2009-11-30
Applicant: (주)아모레퍼시픽
IPC: C12N9/96
Abstract: PURPOSE: A method for stabilizing an enzyme is provided to enhance enzyme stabilitiy and to block enzyme denaturation. CONSTITUTION: A method for stabilizing an enzyme comprises: a step of dispersing the enzyme into polyol to prepare solution 1; a step of dissolving hydrogel in a solvent to prepare solution 2; a step of redispersing solution 1 to solution 2; and a step of adding cross-linking solution and stirring at 40-70°C for 30 minutes to one hour to prepare cross-linked hydrogel. The enzyme is oxidoreductase, transferase, hydrolase, lyase, isomerase, or ligase. The polyol is polyethylene glycol, polypropylene glycol, or copolymer thereof. The hydrogel is gelatin, acacia gum, collagen, or carrageenan gum.
Abstract translation: 目的：提供稳定酶的方法，以增强酶的稳定性和阻断酶的变性。 构成：稳定酶的方法包括：将酶分散到多元醇中以制备溶液1的步骤; 将水凝胶溶解在溶剂中以制备溶液2的步骤; 将溶液1再分散到溶液2的步骤; 并在40-70℃下加入交联溶液并搅拌30分钟至1小时以制备交联水凝胶的步骤。 酶是氧化还原酶，转移酶，水解酶，裂解酶，异构酶或连接酶。 多元醇是聚乙二醇，聚丙二醇或其共聚物。 水凝胶是明胶，阿拉伯树胶，胶原或角叉菜胶。
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Patent Agency Ranking
公开(公告)号：KR1020110039069A
公开(公告)日：2011-04-15
申请号：KR1020090096346
申请日：2009-10-09
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/553 , A61K8/14 , A61K8/4953 , A61Q7/00
Abstract: PURPOSE: A composition containing phosphatidic acid for promoting hair growth is provided to form liposome and to effectively deliver hair growth promoting ingredients to hair follicle. CONSTITUTION: A composition for promoting hair growth contains phosphatidic acid as an active ingredient. The phosphatidic acid is contained as a functional group of lecithin. The lecithin includes phosphatidyl choline, phosphatidyl serine, phosphatidyl ethanol amine, or phosphatidyl glycol. The composition further contains 0.1-20.0 weight% of lecithin.
Abstract translation: 目的：提供含有用于促进毛发生长的磷脂酸的组合物以形成脂质体并有效地将毛发生长促进成分递送至毛囊。 构成：用于促进头发生长的组合物含有磷脂酸作为活性成分。 磷脂酸作为卵磷脂的官能团含有。 卵磷脂包括磷脂酰胆碱，磷脂酰丝氨酸，磷脂酰乙醇胺或磷脂酰乙二醇。 组合物还含有0.1-20.0重量％的卵磷脂。
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公开(公告)号：KR1020110013147A
公开(公告)日：2011-02-09
申请号：KR1020090108203
申请日：2009-11-10
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition containing polymersomes in which peptides or hydrolysed millets are encapsulated is provided to improve whiteninig, elasticity, anti-wrinkling, skin transparency and moisturizing without skin irritation. CONSTITUTION: A cosmetic composition contains polymersomes in which peptides or hydrolyzed millets are encapsulated, as an active ingredient. The polymersome is prepared by synthesizing polylactic acid and polyethylene glycol in a weight ration of 1:1-1:10. The peptide encapsulated in the polymersomes is diaminopropionoyl tripeptide-33, palmitoyl tripeptide-5, palmitoyl pentapeptide-4, acetyl heptapeptie-4, copper tripeptide-1, lysine polypeptide or acetyl tetrapeptide-11. The cosmetic composition is used for skin moisturizing, anti-wrinkling, skin transparency and anti-aging.
Abstract translation: 目的：提供一种包含聚合物囊泡的化妆品组合物，其中肽或水解的密丝被包封，以提高白化度，弹性，抗皱纹，皮肤透明度和保湿，而无皮肤刺激。 构成：化妆品组合物含有聚合物囊泡，其中肽或水解的细丝被包封，作为活性成分。 通过以1：1-1：10的重量比合成聚乳酸和聚乙二醇制备聚合物。 封装在聚合物囊中的肽是二氨基丙酰基三肽-33，棕榈酰三肽-5，棕榈酰五肽-4，乙酰基七肽-4，铜三肽-1，赖氨酸多肽或乙酰四肽-11。 化妆品组合物用于皮肤保湿，抗皱，皮肤透明和抗老化。
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公开(公告)号：KR1020100002478A
公开(公告)日：2010-01-07
申请号：KR1020080062383
申请日：2008-06-30
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition containing Himalaya glacier water is provided to supply the composition to skin and reduce stratum corneum. CONSTITUTION: A cosmetic composition contains 0.1-100 weight% of Himalaya glacier water as an active ingredient. The glacier water is collected from Vilcabamba of Ecuador or Hunza of Himalaya. The glacier water has a structure of forming colloid by nanosized silica. A cosmetic composition is used in the form of skin, nutrition lotion, nutrition cream, massage cream, essence, eye cream, eye essence, cleansing cream, cleansing foam, cleansing water or pack.
Abstract translation: 目的：提供含有喜马拉雅冰川水的化妆品组合物，以将组合物提供给皮肤并减少角质层。 构成：化妆品组合物含有0.1-100重量％的喜马拉雅冰川水作为活性成分。 冰川水从厄瓜多尔的Vilcabamba或喜马拉雅山的Hunza收集。 冰川水具有通过纳米二氧化硅形成胶体的结构。 化妆品组合物以皮肤，营养乳液，营养霜，按摩霜，精华液，眼霜，眼睛精华，清洁霜，清洁泡沫，清洁水或包装的形式使用。
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公开(公告)号：KR1020090093445A
公开(公告)日：2009-09-02
申请号：KR1020080018968
申请日：2008-02-29
Applicant: (주)아모레퍼시픽
CPC classification number: A61H7/002 , A45D44/02 , A45D2200/1054 , A61K2800/28
Abstract: A beauty art utensil is provided, which improves permeability of the external skin preparation active ingredient to the skin through simple massage of the skin. A beauty art utensil makes skin massage possible and includes minute protrusion structure. The minute protrusion provides a mechanism improving the permeability of the external skin preparation active ingredient to the skin by a horny substance softening effect by providing effective contact and strong pressure due to the small area of the minute protrusion when performing skin massage. The pressure of the minute protrusion is 0.1-50MPa.
Abstract translation: 提供美容美体器具，其通过简单的皮肤按摩来改善外用皮肤制剂活性成分对皮肤的渗透性。 美容工具使皮肤按摩成为可能，包括微小的突起结构。 微小突起提供通过在进行皮肤按摩时由于微小突起的小面积而提供有效接触和强力的压力，通过角质物质软化作用提高外用皮肤制剂活性成分对皮肤的渗透性的机制。 微小突起的压力为0.1-50MPa。
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90.发明公开
公开(公告)号：KR1020090070161A
公开(公告)日：2009-07-01
申请号：KR1020070138061
申请日：2007-12-27
Applicant: (주)아모레퍼시픽
CPC classification number: A61Q19/08 , A61K8/11 , A61K8/8117 , A61K8/8147 , A61K8/8152 , A61K2800/412 , A61K2800/63 , B01J13/125 , B01J13/22
Abstract: A double layered polymer capsule is provided to ensure excellent stabilization effect on oxidation-sensitive materials and to prevent the denaturation of an active material from an outside harmful environment. A double layered polymer capsule comprises a core consisting of carotenoid, a cationic polymer layer that surrounds the core, and an anionic polymer layer coated on the surface of a cationic polymer capsule. A method for manufacturing the double layered polymer capsule comprises (i) copolymerizing a monomer having a cationic functional group and a monomer having a hydrophobic group to obtain an cationic polymer; (ii) dissolving the cationic polymer and carotenoid in organic solvent to prepare emulsion, and evaporating the organic solvent to obtain the cationic polymer capsule supported with carotenoid; (iii) copolymerizing a monomer having an anionic functional group to obtain an anionic polymer; and (iv) applying the anionic polymer to the surface of the cationic polymer capsule.
Abstract translation: 提供双层聚合物胶囊以确保对氧化敏感材料的优异的稳定化作用，并防止活性物质从外部有害环境变性。 双层聚合物胶囊包括由类胡萝卜素，包围核心的阳离子聚合物层和涂覆在阳离子聚合物胶囊表面上的阴离子聚合物层组成的核心。 制造双层聚合物胶囊的方法包括（i）使具有阳离子官能团的单体和具有疏水基团的单体共聚以获得阳离子聚合物; （ii）将阳离子聚合物和类胡萝卜素溶解在有机溶剂中以制备乳液，并蒸发有机溶剂以获得由类胡萝卜素支持的阳离子聚合物胶囊; （iii）使具有阴离子官能团的单体共聚得到阴离子聚合物; 和（iv）将阴离子聚合物施加到阳离子聚合物胶囊的表面。
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