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81.
公开(公告)号:KR1020030077271A
公开(公告)日:2003-10-01
申请号:KR1020020016298
申请日:2002-03-26
Applicant: (주)아모레퍼시픽
IPC: C07K5/10
CPC classification number: C07K5/1016 , A61K8/64 , A61K38/07 , A61Q19/00 , A61Q19/02
Abstract: PURPOSE: Provided is a melanogenesis-suppressing peptide which effectively suppresses the activation of tyrosinase in the melanogenesis cells. A topical skin-whitening composition containing the melanogenesis-suppressing peptide involves excellent skin whitening effect, and effective improvement and prevention of chloasma, freckles, and other melanin pigmentation. CONSTITUTION: The melanogenesis-suppressing peptide is selected from the group consisting of peptides with the amino acid sequences of SEQ ID NO 1-4. A method of manufacturing the melanogenesis-suppressing peptide comprises the steps of preparing chemical peptide random-sequenced mixtures with 76 cases of 4(locations)x19(amino acids); selecting two or three amino acids per the respective peptide locations with enzyme activity inhibitory effect from the peptide mixtures using tyrosinase extracted from mushrooms; synthesizing secondary peptides based on the selected peptide sequences; and testing the whitening effect and the cell stability of the secondary peptides, and finally selecting the peptide with the amino acid sequences of SEQ ID NO 1-4.
Abstract translation: 目的:提供有效抑制黑素生成细胞中酪氨酸酶活化的黑素生成抑制肽。 含有黑素生成抑制肽的局部皮肤美白组合物具有优异的皮肤美白效果,有效改善和防止黄褐斑,雀斑和其他黑色素色素沉着。 构成:黑素生成抑制肽选自具有SEQ ID NO 1-4的氨基酸序列的肽。 制备黑素生成抑制肽的方法包括以下步骤:制备具有76个4(位置)x19(氨基酸)的76个化学肽随机排序的混合物; 使用从蘑菇提取的酪氨酸酶从肽混合物中选择两个或三个氨基酸,每个肽位置具有酶活性抑制作用; 基于所选择的肽序列合成二级肽; 并测试第二肽的美白效果和细胞稳定性,最后选择具有SEQ ID NO 1-4的氨基酸序列的肽。
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公开(公告)号:KR101876471B1
公开(公告)日:2018-07-16
申请号:KR1020100049181
申请日:2010-05-26
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/48 , A23L2/52 , A23L33/105 , A61K2236/333
Abstract: 본발명은저농도저급알코올로추출한콩 추출물또는그 분획물을함유하는조성물에관한것이다. 상기조성물은혈액순환개선효과가우수하고, 비만상태를개선시키며, 당뇨및 고질혈증등의예방, 증상의완화또는치료에효과적이다.
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84.
公开(公告)号:KR101698919B1
公开(公告)日:2017-01-23
申请号:KR1020090098051
申请日:2009-10-15
Applicant: (주)아모레퍼시픽
CPC classification number: A23F3/14 , A23V2002/00 , A23V2200/326
Abstract: 차(tea)에장류유래균주를접종하여얻은발효차및 상기발효차를제조하는방법이개시되며, 상기발효차는, 맛과향취가뛰어나며, 우수한혈액순환개선효능및 수족냉증개선효능을나타내어, 건강식품또는의약품분야에서다양하게활용가능하다.
Abstract translation: 公开了通过用发酵酱油生产的微生物菌株接种茶而得到的发酵茶,以及发酵茶的制造方法。 发酵茶具有优越的味道和香气,对血液循环有显着的改善作用,对手脚和脚部的减轻效果,可用于保健食品或医疗产品领域的各种方式。
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公开(公告)号:KR1020160128277A
公开(公告)日:2016-11-07
申请号:KR1020160140904
申请日:2016-10-27
Applicant: (주)아모레퍼시픽
IPC: A61K36/48 , A23L33/105
Abstract: 본발명은유색콩등으로부터추출한유색콩추출물의분획물을유효성분으로함유하는항혈전효능조성물에관한것이다. 본발명에의한항혈전조성물은아데노신을포함하고있으며, 혈전형성의원인이되는심장혈관질환, 뇌혈관질환, 동맥경화증, 고혈압, 당뇨등의순환기계질환의치료에매우유용하게이용될수 있다.
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公开(公告)号:KR1020160073950A
公开(公告)日:2016-06-27
申请号:KR1020160071842
申请日:2016-06-09
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/48 , A23L33/105 , A23V2200/30 , A23V2200/326
Abstract: 본발명은유색콩등으로부터추출한유색콩추출물및 그분획물을유효성분으로함유하는항혈전효능조성물에관한것이다. 본발명에의한항혈전조성물은아데노신을포함하고있으며, 혈전형성의원인이되는심장혈관질환, 뇌혈관질환, 동맥경화증, 고혈압, 당뇨등의순환기계질환의치료에매우유용하게이용될수 있다.
Abstract translation: 本发明涉及抗紫外线组合物,其含有作为活性成分的从有色豆及其部分提取的有色豆提取物。 本发明的抗血栓形成组合物含有腺苷,可用于治疗血栓形成原因的心血管疾病,脑血管疾病,动脉粥样硬化,高血压,糖尿病等循环系统疾病。
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公开(公告)号:KR1020140108170A
公开(公告)日:2014-09-05
申请号:KR1020140023887
申请日:2014-02-28
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/65 , A23L33/18 , A23V2002/00 , A61K8/735 , A61K9/0095 , A61K9/2059 , A61K9/4875 , A61K31/728 , A61K36/258 , A61K38/005 , A61K38/06 , A61K38/39 , A61K2800/91 , A61Q19/00 , A61Q19/08 , A61K2300/00
Abstract: The present invention relates to composition which contains collagen as an active ingredient for maintaining an effect of filler for a long period of time. The composition contains 0.01-50 wt% of collagen peptides with respect to the total weight of the composition. The collagen peptides contain collagen tripeptide Gly-X-Y. According to the present invention, the composition can promote synthesis of hyaluronic acid and can inhibit activity of hyaluronidase.
Abstract translation: 本发明涉及包含胶原作为长期保持填料效果的活性成分的组合物。 该组合物相对于组合物的总重量含有0.01-50重量%的胶原肽。 胶原肽含有胶原三肽Gly-X-Y。 根据本发明,组合物可以促进透明质酸的合成并且可以抑制透明质酸酶的活性。
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公开(公告)号:KR1020130022477A
公开(公告)日:2013-03-07
申请号:KR1020110084745
申请日:2011-08-24
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/48 , A23V2200/326 , A61K2236/333 , Y10S514/929
Abstract: PURPOSE: A composition containing a bean extract is provided to reduce blood pressure through suppression of vasoconstriction. CONSTITUTION: A composition containing a bean extract for controlling blood vessels contains a bean extract which is prepared using 1-70%(v/v) of C1-C5 alcohol or a fraction thereof. C1-C5 alcohol is selected from a group consisting of methanol, ethanol, isopropyl alcohol, n-propyl alcohol, n-butanol, and isobutanol. [Reference numerals] (AA) Blood vessel extraction(%, 90mMK^+); (BB) Control group; (CC) Black soybean; (DD) White soybean
Abstract translation: 目的:提供含有豆提取物的组合物,以通过抑制血管收缩来降低血压。 构成:含有用于控制血管的豆提取物的组合物含有使用1-70%(v / v)的C1-C5醇或其一部分制备的豆提取物。 C1-C5醇选自甲醇,乙醇,异丙醇,正丙醇,正丁醇和异丁醇组成的组。 (附图标记)(AA)血管提取(%,90mM K +); (BB)对照组; (CC)黑豆; (DD)白豆
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公开(公告)号:KR1020120064299A
公开(公告)日:2012-06-19
申请号:KR1020100125468
申请日:2010-12-09
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/82 , A61K36/44 , A61K36/48 , A61K2236/19 , C12P1/04
Abstract: PURPOSE: A composition containing fermented tea extract is provided to reduce body fat and to prevent or treat obesity and cardiovascular diseases. CONSTITUTION: A composition for reducing body fat level contains fermented tea extract as an active ingredient which is prepared by inoculating strain to tea. A composition for suppressing lipid decomposition contains the fermented tea extract as an active ingredient. The tea includes green tea, white tea, oolong tea, pure tea, black tea, or persimmon leaf tea. The strain includes Bacillus subtilis, Bacillus licheniformis, Bacillus megateriums, Bacillus natto, Bacillus citreus, Bacillus circulans, Bacillus mesentricus, or Bacillus pumilus.
Abstract translation: 目的:提供含有发酵茶提取物的组合物,以减少体内脂肪,预防或治疗肥胖和心血管疾病。 构成:用于降低体脂肪含量的组合物含有作为活性成分的发酵茶提取物,其通过将菌株接种到茶中而制备。 用于抑制脂质分解的组合物含有发酵茶提取物作为活性成分。 茶包括绿茶,白茶,乌龙茶,纯茶,红茶或柿子茶。 该菌株包括枯草芽孢杆菌,地衣芽孢杆菌,巨大芽孢杆菌,纳豆芽孢杆菌,柠檬酸芽孢杆菌,环状芽孢杆菌,肠杆菌或短小芽孢杆菌。
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90.
公开(公告)号:KR1020090064743A
公开(公告)日:2009-06-22
申请号:KR1020070132054
申请日:2007-12-17
Applicant: (주)아모레퍼시픽
Abstract: A composition of skin external preparation or cosmetic food for promoting proline recycling is provided to promote the expression or activation of prolidase. A composition of skin external preparation for promoting proline recycling comprises a theanine as an active ingredient. The theanine is contains in a ratio of 0.001-10 weight% based on the total weight. A cosmetic food product contains the theanine as an active ingredient. The theanine is contained in a ratio of .1-40 weight% based on the total weight. The composition of skin external preparation or cosmetic food product for promoting proline recycling promotes the synthesis of collagen and prevent skin wrinkle.
Abstract translation: 提供用于促进脯氨酸回收的皮肤外用制剂或化妆品食品的组合物以促进脯氨酸酶的表达或活化。 用于促进脯氨酸回收的皮肤外用制剂组合物包括茶氨酸作为活性成分。 所述茶氨酸含量相对于总重量为0.001-10重量%。 化妆品食品含有茶氨酸作为活性成分。 茶氨酸的含量占总重量的1-40重量%。 用于促进脯氨酸回收的皮肤外用制剂或化妆品食品的组成促进胶原蛋白的合成并防止皮肤皱纹。
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