公开(公告)号：NO970163L

公开(公告)日：1997-03-14

申请号：NO970163

申请日：1997-01-14

Applicant: BASF AG

Inventor： HELLENDAHL BEATE ,  LANSKY ANNEGRET ,  RENDENBACH-MUELLER BEATRICE ,  BACH ALFRED ,  UNGER LILIANE ,  TESCHENDORF HANS-JUERGEN ,  WICKE KARSTEN

IPC: A61K31/33 ,  A61K31/415 ,  A61K31/44 ,  C07D233/84 ,  A61K31/4402 ,  A61K31/4406 ,  A61K31/4409 ,  A61K31/4418 ,  A61K31/4425 ,  A61K31/445 ,  A61K31/495 ,  A61K31/496 ,  A61P25/18 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  C07D213/56 ,  C07D213/64 ,  C07D213/65 ,  C07D213/70 ,  C07D213/73 ,  C07D213/79 ,  C07D213/81 ,  C07D233/90 ,  C07D307/79 ,  C07D333/24 ,  C07D333/28 ,  C07D333/38 ,  C07D471/18

Abstract: PCT No. PCT/EP95/02782 Sec. 371 Date Jan. 14, 1997 Sec. 102(e) Date Jan. 14, 1997 PCT Filed Jul. 14, 1995 PCT Pub. No. WO96/02246 PCT Pub. Date Feb. 1, 1996The present invention relate to the use of heterocyclic compounds of the following formula:Het-A-B-Arwhere Het, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.

公开(公告)号：NO970161L

公开(公告)日：1997-03-14

申请号：NO970161

申请日：1997-01-14

Applicant: BASF AG

Inventor： HELLENDAHL BEATE ,  LANSKY ANNEGRET ,  MUNSCHAUER RAINER ,  BIALOJAN SIEGFRIED ,  UNGER LILIANE ,  TESCHENDORF HANS-JUERGEN ,  WICKE KARSTEN ,  DRESCHER KARLA

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/435 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/505 ,  A61K31/53 ,  A61P1/08 ,  A61P25/18 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  C07D249/12 ,  C07D249/14 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14

Abstract: PCT No. PCT/EP95/02781 Sec. 371 Date Jan. 14, 1997 Sec. 102(e) Date Jan. 14, 1997 PCT Filed Jul. 14, 1995 PCT Pub. No. WO96/02520 PCT Pub. Date Feb. 1, 1996The present invention relates to triazole compounds of the following formula: where R1, R2, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.

公开(公告)号：HU9700113D0

公开(公告)日：1997-02-28

申请号：HU9700113

申请日：1995-07-14

Applicant: BASF AG

Inventor： BIALOJAN SIEGFRIED ,  DRESCHER KARLA ,  HELLENDAHL BEATE ,  LANSKY ANNEGRET ,  MUNSCHAUER RAINER ,  TESCHENDORF HANS-JUERGEN ,  UNGER LILIANE ,  WICKE KARSTEN

IPC: C07D239/26 ,  A61K31/505 ,  A61K31/506 ,  A61P25/16 ,  A61P25/24 ,  A61P25/26 ,  C07D239/38 ,  C07D239/46 ,  C07D239/56 ,  C07D239/60 ,  C07D401/00 ,  C07D401/12

Abstract: The present invention relates to the use of pyrimidine compounds of the following formula:wherein R1, R2, R3, A, B and Ar have the meanings indicated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.

公开(公告)号：HU9700109D0

公开(公告)日：1997-02-28

申请号：HU9700109

申请日：1995-07-14

Applicant: BASF AG

Inventor： BIALOJAN SIEGFRIED ,  DRESCHER KARLA ,  HELLENDAHL BEATE ,  LANSKY ANNEGRET ,  MUNSCHAUER RAINER ,  TESCHENDORF HANS-JUERGEN ,  UNGER LILIANE ,  WICKE KARSTEN

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/435 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/505 ,  A61K31/53 ,  A61P1/08 ,  A61P25/18 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  C07D249/12 ,  C07D249/14 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14

Abstract: PCT No. PCT/EP95/02781 Sec. 371 Date Jan. 14, 1997 Sec. 102(e) Date Jan. 14, 1997 PCT Filed Jul. 14, 1995 PCT Pub. No. WO96/02520 PCT Pub. Date Feb. 1, 1996The present invention relates to triazole compounds of the following formula: where R1, R2, A, B and Ar have the meanings stated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.

公开(公告)号：CA2195243A1

公开(公告)日：1996-02-01

申请号：CA2195243

申请日：1995-07-14

Applicant: BASF AG

Inventor： HELLENDAHL BEATE ,  LANSKY ANNEGRET ,  MUNSCHAUER RAINER ,  BIALOJAN SIEGFRIED ,  UNGER LILIANE ,  TESCHENDORF HANS-JUERGEN ,  WICKE KARSTEN ,  DRESCHER KARLA

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/435 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/505 ,  A61K31/53 ,  A61P1/08 ,  A61P25/18 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  C07D249/12 ,  C07D249/14 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14

Abstract: The present invention relates to triazole compounds of formula (I) in which R1, R2 stand for H or different substituents, A stands for a bivalent group, B stands for a rest of the formula (a), (b) or (c) and Ar stands for optionally substituted phenyl, pyridyl, pyrimidyl or triazinyl. The compounds of the invention have a high affinity for the dopamine-D3-receptor and are therefore usable for the treatment of diseases responding to dopamine-D3-ligands.

公开(公告)号：CA2195241A1

公开(公告)日：1996-02-01

申请号：CA2195241

申请日：1995-07-14

Applicant: BASF AG

Inventor： HELLENDAHL BEATE ,  LANSKY ANNEGRET ,  MUNSCHAUER RAINER ,  BIALOJAN SIEGFRIED ,  UNGER LILIANE ,  TESCHENDORF HANS-JUERGEN ,  WICKE KARSTEN ,  DRESCHER KARLA

IPC: C07D239/26 ,  A61K31/505 ,  A61K31/506 ,  A61P25/16 ,  A61P25/24 ,  A61P25/26 ,  C07D239/38 ,  C07D239/46 ,  C07D239/56 ,  C07D239/60 ,  C07D401/00 ,  C07D401/12

Abstract: The use is disclosed of pyrimidine compounds having the formula (I), in which R1, R2, R3, A, B and Ar have the meanings given in the description. These compounds have a high affinity for the dopamine D3 receptor and are therefore useful for treating diseases that respond to dopamine D3 ligands.

公开(公告)号：NO944476L

公开(公告)日：1994-12-09

申请号：NO944476

申请日：1994-11-22

Applicant: BASF AG

Inventor： HELLENDAHL BEATE ,  SCHLECKER RAINER ,  ROEHL FRANZ ,  ZIPPLIES MATTHIAS ,  RASCHACK MANFRED ,  HAFNER MATTHIAS

IPC: A61K31/47 ,  C07D217/04 ,  C07D217/06

公开(公告)号：FI945488A0

公开(公告)日：1994-11-22

申请号：FI945488

申请日：1994-11-22

Applicant: BASF AG

Inventor： HELLENDAHL BEATE ,  SCHLECKER RAINER ,  ROEHL FRANZ ,  ZIPPLIES MATTHIAS ,  RASCHACK MANFRED ,  HAFNER MATTHIAS

IPC: A61K31/47 ,  A61K31/472 ,  A61P9/00 ,  A61P31/04 ,  C07D217/04 ,  C07D217/06 ,  C07D

公开(公告)号：HU9302315D0

公开(公告)日：1993-11-29

申请号：HU9302315

申请日：1993-08-10

Applicant: BASF AG

Inventor： WINGERT HORST ,  HELLENDAHL BEATE ,  KIRSTGEN REINHARD ,  SAUTER HUBERT ,  AMMERMANN EBERHARD ,  LORENZ GISELA

IPC: A01N37/42 ,  A01N37/10 ,  A01N37/34 ,  A01N37/36 ,  A01N37/50 ,  A01N43/10 ,  A01N43/40 ,  A01N43/78 ,  A01N43/80 ,  A01N43/84 ,  A01N55/00 ,  C07C69/618 ,  C07C69/734 ,  C07C69/738 ,  C07C69/76 ,  C07C205/56 ,  C07C233/31 ,  C07C233/54 ,  C07C251/48 ,  C07C255/23 ,  C07C255/62 ,  C07C323/57 ,  C07C323/60 ,  C07D213/54 ,  C07D213/55 ,  C07D213/56 ,  C07D215/12 ,  C07D217/16 ,  C07D231/12 ,  C07D233/92 ,  C07D261/08 ,  C07D271/10 ,  C07D271/107 ,  C07D277/20 ,  C07D277/22 ,  C07D277/58 ,  C07D277/66 ,  C07D285/12 ,  C07D307/54 ,  C07D307/71 ,  C07D317/60 ,  C07D319/18 ,  C07D333/24 ,  C07D333/28 ,  C07D333/38 ,  C07D333/42 ,  C07D413/12 ,  C07D521/00 ,  C07F7/10 ,  C07F7/22

Abstract: Acetylene derivatives of the general formula I in which U, V and W denote hydrogen, halogen, nitro, cyano, alkyl and alkoxy, A denotes alkylidene, alkoxymethylidene, alkylthiomethylidene and alkoximino, B denotes OH, alkoxy and alkylamino and R denotes hydrogen, halogen, cyano, CF3, alkyl, cycloalkyl, haloalkyl, aryl, alkenyl, alkinyl, heterocyclyl, heteroaryl, arylalkyl, arylalkenyl, arylethinyl, heteroaryl-C1-C4-alkyl, C1-C4-alkoxy-C1-C4-alkyl, aryloxyalkyl, heteroaryloxyalkyl, arylamino-alkyl, arylthiomethyl, heteroarylthiomethyl, C(O)R , C(O)NR R , C(S)NR R , C(O)SR , C(S)OR , C(S)SR , CH(OH)R )R , SiR R R , SnR R R , C(OR)R , C(=N-OR )R , and the radicals R -R , R and R denote hydrogen, alkyl, aryl, heteroaryl, arylalkyl and heteroarylalkyl, and fungicides containing these compounds.

公开(公告)号：AU642810B2

公开(公告)日：1993-10-28

申请号：AU1103792

申请日：1992-02-19

Applicant: BASF AG

Inventor： HARREUS ALBERT ,  SAUTER HUBERT ,  HELLENDAHL BEATE ,  DOETZER REINHARD ,  AMMERMANN EBERHARD ,  LORENZ GISELA

IPC: A01N37/50 ,  A01N43/54 ,  A01N43/58 ,  A01N43/76 ,  A01N43/836 ,  C07C69/65 ,  C07C69/653 ,  C07C69/734 ,  C07C69/738 ,  C07C251/48 ,  C07C251/50 ,  C07C251/52 ,  C07C251/54 ,  C07C251/56 ,  C07C251/58 ,  C07C251/60 ,  C07C251/86 ,  C07C255/15 ,  C07C255/57 ,  C07C255/58 ,  C07C255/62 ,  C07D213/77 ,  C07D239/42 ,  C07D241/20 ,  C07D263/32 ,  C07D333/28 ,  A01N33/26 ,  A01N33/16 ,  C07D213/30 ,  C07D213/61 ,  C07D213/26 ,  C07D213/80 ,  C07D213/50 ,  C07D241/12 ,  C07D241/42 ,  C07D237/08 ,  C07D207/14 ,  C07D333/56 ,  C07D261/08 ,  C07D261/10 ,  C07D209/12 ,  C07D213/42 ,  C07D303/36 ,  C07D303/48 ,  C07D303/08 ,  C07D285/10 ,  C07D285/12 ,  C07D239/26 ,  C07D239/74 ,  C07D215/12 ,  C07D215/38 ,  C07D215/40 ,  C07D215/44 ,  C07D473/00 ,  C07D473/40 ,  C07D473/32 ,  C07D277/28 ,  C07D277/50 ,  C07D277/82 ,  C07D263/48 ,  C07D253/07 ,  C07D249/04

Abstract: Iminoalkyl-phenylacrylic acid derivs. (I) ar new: R = H or 1-6C alkyl; R = H; 1-4C alkyl opt. substd. by halo; or opt. substd. aryl; Z ,Z = H; halo; CN; NO2;etc.;Y = O; NH; or NR ; and R = H; 1-4C alkoxycarbonyl-1-4C alkyl; or opt. substd. alkyl, cycloalkyl, etc.; or Y+R form a ring which is opt. substd. when Y = NH or NR ; R = 1-6C alkyl; X = CH-1-4C alkoxy or CH-1-4C alkylthio (also 1-4C alkylidene and 1-4C alkoxyimino in the description).