Abstract:
A device and method for permitting the separation of plasma or serum from whole blood. The device comprises a matrix of hydrophilic sintered porous material to which at least one red blood cell agglutinating agent has been applied. According to a first method of using the device, a sample of whole blood is applied to a first end of the matrix and the red blood cells within the sample come in contact with the agglutinating agents present in the matrix. The blood cells agglutinate, and are entrapped in the interstices of the matrix, while substantially blood-cell-free serum or plasma accumulates near the outlet of the device. A filter means in liquid receiving relationship with the matrix functions to wick the serum or plasma from the matrix. According to an alternative aspect of the invention, a filter means in liquid receiving relationship with the outlet of the matrix functions to retain any blood cells which pass through the matrix as the filter means wicks the plasma or serum from the matrix. Additional agglutinating agents may be incorporated within the filter means to facilitate retention of blood cells which pass through the matrix. Another aspect of the present invention involves a device for the measurement of a serum or plasma sample, utilizing a matrix of sintered porous material, such as sintered glass, sintered steel, sintered ceramics, sintered plastics, and eguivalents thereof. The matrix is characterized by a reproducible fluid uptake capacity proportional to the fixed dimensions of said matrix, a minimal reactivity with plasma or serum components, and a hydrophilic internal surface which enables the matrix to collect and retain a predetermined volume of sample for analysis. A further aspect of the present invention provides a porous reagent delivery system comprising a matrix of sintered porous material containing at least one reagent in a freeze-dried state, and method for making same. The system allows the delivery of a unitized form of a freeze-dried reagent which is recoverable upon contact with a liquid.
Abstract:
1. Verfahren zur Herstellung von offenporigen Sinterkörpern aus Glas mit großem offenen Porenvolumen, das besonders geeignet ist als Filter für Flüssigkeiten und Gase bei hohen Durchflußgeschwindigkeiten. 2.1. Offenporiges Sinterglas wird nach herkömmlichen Verfahren hergestellt, wobei sich jedoch bei Porenvolumina von mehr als 60 % Biegezugfestigkeiten ergeben, die für eine Anwendung als Filtermedium zu niedrig sind. Ungüstig für die Filtration ist weiterhin die breite Verteilung der Porengröße sowie die Strukturierung der inneren Oberfläche der Poren. Das neue Verfahren soll offenporiges Sinterglas mit großen offenen Porenvolumen, hohen Biegezugfestigkeiten und guten Durchflußgeschwindigkeiten liefern. 2.2. Bei diesem Verfahren wird zunächst ein Ausgangsgranulat aus feinkörnigem Glaspulver, grobkörnigem Salzpulver und Bindemittel hergestellt. Diesem Ausgangsgranulat wird dann 5 bis 20 Gew.-% feinkörniges Glaspulver zugesetzt und diese Masse einer Formgebung unterzogen. Anschließend wird der so entstandene Formkörper auf die Sintertemperatur des Glases erhitzt und versintert und danach wird das Salz aus dem Sinterglas herausgewaschen. 2.3. Herstellung von offenporigem Sinterglas für Filter.
Abstract:
Ein Verfahren zur Herstellung von porösen Sinterkörpern mit großem offenem Porenvolumen und definierten Porendurchmessern besteht darin, daß ein Sintermaterial in Form eines feingemahlenen Pulvers mit einer löslichen Substanz von definierter Korngrösse, deren Schmelzpunkt über der Sintertemperatur des Sintermaterials liegt, vermischt und bei der Sintertemperatur des Sintermaterials versintert wird, worauf die lösliche Substanz aus dem Sinterprodukt herausgelöst wird.
Abstract:
Methods and devices for isolating nucleic acids from a mixture containing such nucleic acids and extraneous matter are provided. In one embodiment, the method of the invention comprises passing the mixture through a glass frit under conditions effective to separate the nucleic acids from the extraneous matter. In a more specific embodiment, the glass frit is a sintered glass frit.
Abstract:
PURPOSE: A filtering device is provided to have super high speed filtering functionality and backfresh function by preventing various kinds of contaminants from flowing into the water and remarkably improving filtering performance. CONSTITUTION: A filtering device equipped with super high speed filtering functionality and backfresh function includes a floc forming bath(10), a filter tub(20), a blasting part for backwashing, and a sludge thickener(30). A guide tube(11) passes through the sidewall of the filter tub from the floc forming bath. An exhaust line(260) includes an upper discharge pipe(220) arranged on the first screen and a bottom outlet(270) arranged under the second screen. The contaminated water transferred to the guide tube is filtered through the porosity floating member and discharge the processing water to the upper discharge pipe.
Abstract:
본 발명의 과제는 여과 필터 등으로서 장기간 사용할 수 있으며 내산성 및 내알칼리성이 우수한 유리를 결합재로 하는 세라믹 다공체를 제공하는 것이다. Li 2 O, Na 2 O, K 2 O, MgO, CaO, SrO 및 BaO로 이루어진 군에서 선택되고, 적어도 Li 2 O, Na 2 O 및 K 2 O 중 임의의 2종 이상의 알칼리 금속 산화물을 포함하는 복수 종의 금속 산화물이 5∼20 mol%, ZrO 2 와 TiO 2 중 어느 하나 또는 양자가 총량으로서 3 mol% 이상, 잔부가 SiO 2 와 불가피 불순물인 유리를 결합재로 하여, 세라믹 입자를 결합하여 이루어지는 세라믹 다공체가 제공된다.