公开(公告)号：US20160216249A1

公开(公告)日：2016-07-28

申请号：US15005850

申请日：2016-01-25

Applicant: Siemens Healthcare Diagnostics Products GmbH

Inventor： Karl Sass

IPC: G01N33/49 ,  G01N21/31

CPC classification number: G01N33/492 ,  G01N21/274 ,  G01N21/314 ,  G01N21/3151 ,  G01N2201/06146

Abstract: The present invention relates to a method and an automatic analyzer for determining more accurately the concentration of lipids and other interfering substances in body fluids, particularly of interfering substances such as bilirubin and hemoglobin in blood serum and blood plasma samples.

Abstract translation: 本发明涉及一种用于更准确地测定体液中脂质和其它干扰物质，特别是血清和血浆样品中干扰物质如胆红素和血红蛋白的浓度的方法和自动分析仪。

公开(公告)号：US20160175620A1

公开(公告)日：2016-06-23

申请号：US14948430

申请日：2015-11-23

Applicant: COLORIGHT LTD.

Inventor： Benzion LANDA ,  Efraim MIKLATZKY ,  Sagi ABRAMOVICH ,  Yacov MAZUZ ,  Anton KRASSILNIKOV ,  Eliyahu BENNY ,  Gilad DAVARA ,  Chen OFEK ,  Elena ISHKOV ,  Lior SHAHAR ,  Daniel MANDELIK ,  Uri ZADOK

IPC: A61Q5/10 ,  A61K8/73 ,  A61K8/81 ,  A61K8/41 ,  G01N33/483 ,  A61K8/34 ,  A61K8/46 ,  A61K8/40 ,  A45D44/02 ,  G01N21/47 ,  A61K8/02 ,  A61K8/49

CPC classification number: A61Q5/10 ,  A45D19/02 ,  A45D44/005 ,  A45D44/02 ,  A45D2044/007 ,  A45D2200/058 ,  A61K8/0216 ,  A61K8/347 ,  A61K8/40 ,  A61K8/415 ,  A61K8/463 ,  A61K8/4926 ,  A61K8/494 ,  A61K8/73 ,  A61K8/731 ,  A61K8/732 ,  A61K8/817 ,  A61K8/8176 ,  A61K2800/4324 ,  A61K2800/48 ,  A61K2800/87 ,  B01F1/0022 ,  B01F13/1058 ,  B01F13/1063 ,  B01F15/0216 ,  G01N21/4738 ,  G01N33/4833 ,  G01N2201/06146

Abstract: Novel systems and methods for performing treatment (e.g., coloration) of keratinous fibers are disclosed. The methods and systems utilize one or more of a dispensing device which is configured to provide customized composition for treating keratinous fibers (e.g., a coloring composition), optionally formed from tablets; an optical reader, for obtaining sufficient characteristics of the keratinous fibers to make a realistic prediction of the outcome of a treatment (e.g., coloring treatment); a computational units for predicting an outcome of a treatment, optionally being interfaced with the dispensing device and for selecting a customized treatment; and tablet formulations which are useful in preparing customized composition for treating keratinous fibers. Further disclosed are rapidly disintegrating tablets for use in the preparation of compositions for treating keratinous fibers.

公开(公告)号：US09250193B2

公开(公告)日：2016-02-02

申请号：US13575067

申请日：2011-01-26

Applicant: James Gordon Charters Smith

Inventor： James Gordon Charters Smith

IPC: G01N21/87 ,  G01N33/38 ,  G01N21/55

CPC classification number: G01N21/87 ,  G01N21/55 ,  G01N33/381 ,  G01N2201/06146 ,  G01N2201/0634

Abstract: A system is described for obtaining images of a gemstone, and performing quantitative analysis on the images to obtain measures of properties of the gemstone. The system comprises a support structure for supporting the gemstone at an observation position. An illumination structure is arranged to illuminate the gemstone. The illumination structure comprises a plurality of radially dispersed directional light sources directed towards the observation position, the support structure and illumination system being rotatable relative to one another around a rotation axis so that the gemstone can be illuminated by one or more of the directional light sources at each of a plurality of rotational positions, the axis of rotation being normal to a selected facet of the gemstone. An imaging device is directed towards the gemstone for obtaining images of the gemstone at each of the rotational positions, the imaging device having an imaging axis parallel to or coincident with the axis of rotation. An image processor is provided for identifying sparkle regions in the images corresponding to reflections from individual light sources by individual facets and providing a quantitative measure of the gemstone on the basis of porperties of the sparkle regions.

Abstract translation: 描述了一种用于获得宝石图像的系统，并对图像进行定量分析以获得宝石特性的度量。 该系统包括用于在观察位置支撑宝石的支撑结构。 布置照明结构来照亮宝石。 照明结构包括指向观察位置的多个径向分散的定向光源，支撑结构和照明系统可围绕旋转轴线相对于彼此旋转，使得宝石能够被一个或多个定向光源 在多个旋转位置中的每一个处，所述旋转轴线垂直于所述宝石的选定小面。 成像装置被引向宝石，以在每个旋转位置获得宝石的图像，成像装置具有与旋转轴线平行或重合的成像轴。 提供图像处理器用于识别对应于各个光源的各个光源的反射的图像中的闪耀区域，并且基于闪光区域的特征提供宝石的定量测量。

公开(公告)号：US20150268165A1

公开(公告)日：2015-09-24

申请号：US14644717

申请日：2015-03-11

Applicant: KONICA MINOLTA, INC.

Inventor： Keita SAITO ,  Midori SHIMOMURA ,  Dai SUWAMA ,  Sayaka MORITA

IPC: G01N21/49 ,  G01N21/55

CPC classification number: G01N21/49 ,  G01N21/55 ,  G01N2201/06146 ,  G01N2201/124

Abstract: A processing apparatus includes: a light emission unit configured to emit light to a surface of a particle dispersed liquid applied to a base material, the particle dispersed liquid having particles dispersed in a solvent; a reflected light amount monitoring unit configured to detect an amount of the light reflected, and monitor a temporal variation of the detected value; and a condition adjustment unit configured to adjust a condition for a particle securing process, the particle securing process being performed to remove the solvent and secure the particles onto the base material, wherein, when the temporal variation falls within a predetermined range after the value has reached an extreme value, securing of the particles is determined to have been completed.

Abstract translation: 一种处理装置包括：发光单元，被配置为向施加到基材的颗粒分散液体的表面发光，所述颗粒分散液体具有分散在溶剂中的颗粒; 反射光量监视单元，被配置为检测反射的光量，并监视检测值的时间变化; 以及条件调整单元，被配置为调整用于颗粒固定过程的条件，进行所述颗粒固定处理以除去溶剂并将颗粒固定在基材上，其中，当所述时间变化落在所述值具有 达到极限值，确定颗粒的确定已经完成。

公开(公告)号：US08547552B2

公开(公告)日：2013-10-01

申请号：US13121712

申请日：2009-10-09

Applicant: Cheung Hoi Albert Yu ,  Lok Ting Lau

Inventor： Cheung Hoi Albert Yu ,  Lok Ting Lau

IPC: G01N21/00

CPC classification number: G01N21/00 ,  G01N21/253 ,  G01N21/554 ,  G01N33/587 ,  G01N2021/258 ,  G01N2021/3185 ,  G01N2201/06146

Abstract: A method for detecting a target analyte associated with nano-sized gold- and/or silver-containing detecting labels in a microarray of samples. The labels indicate presence or absence of a target analyte in a sample. The method includes sequentially illuminating at least two sample groups with at least two different monochromatic light beams. The sample groups include (a) a first sample group containing at least one sample potentially containing the target analyte, and (b) a second sample group serving as positive control or negative control. The method also includes (ii) detecting intensity of light reflected, absorbed, or emitted from each of the sample groups when illuminated with each of the monochromatic light beams. (iii) recording groups of values associated with the intensity reflected, absorbed, or emitted light. (iv) comparing the groups of values associated with the sample groups; and (v) determining the presence of the target analyte based on the comparison.

Abstract translation: 一种用于检测与样品微阵列中的纳米尺寸的含金和/或含银检测标签物相关的目标分析物的方法。 标签表示样品中存在或不存在目标分析物。 该方法包括用至少两个不同的单色光束顺序地照射至少两个样本组。 样品组包括（a）含有至少一种可能含有目标分析物的样品的第一样品组，和（b）用作阳性对照或阴性对照的第二样品组。 该方法还包括（ii）当用每个单色光束照射时，检测从每个样本组反射，吸收或发射的光的强度。 （iii）记录与反射，吸收或发射的光强度相关联的值的组。 （iv）比较与样本组相关的值组; 和（v）基于比较确定目标分析物的存在。

公开(公告)号：US20120057145A1

公开(公告)日：2012-03-08

申请号：US13029992

申请日：2011-02-17

Applicant: James W. Tunnell ,  Brandon Nichols ,  Narasimhan Rajaram ,  Sheldon F. Bish ,  Liang Lim

Inventor： James W. Tunnell ,  Brandon Nichols ,  Narasimhan Rajaram ,  Sheldon F. Bish ,  Liang Lim

IPC: G01J3/42 ,  G01N21/00 ,  G01N21/55 ,  G01J3/44

CPC classification number: G01N21/474 ,  A61B5/0075 ,  A61B5/444 ,  G01J3/42 ,  G01N21/31 ,  G01N21/6486 ,  G01N21/65 ,  G01N2021/1736 ,  G01N2021/174 ,  G01N2201/0221 ,  G01N2201/06113 ,  G01N2201/06146 ,  G01N2201/0833

Abstract: Systems comprising an optical fiber switch connected to a light source and an optical fiber probe, the optical fiber probe comprising a first optical fiber connected to the optical fiber switch and a second optical fiber connected to a spectrophotometer. Methods for determining one or more tissue parameters comprising: emitting light from a first optical fiber into a tissue; collecting the light reemitted from the tissue with a second optical fiber; generating a spectra of the light reemitted from the tissue with a spectrophotometer; and utilizing a look-up table based algorithm to determine one or more tissue parameters, wherein the lookup-table based algorithm comprises the steps of: generating a look-up table by measuring the functional form of a reflectance measured by the spectrophotometer using one or more calibration standards with known optical properties; and implementing an iterative fitting routine based on the lookup-table.

Abstract translation: 包括连接到光源的光纤开关和光纤探针的系统，所述光纤探针包括连接到光纤开关的第一光纤和连接到分光光度计的第二光纤。 用于确定一个或多个组织参数的方法，包括：将光从第一光纤发射到组织中; 用第二光纤收集从组织再发射的光; 用分光光度计产生从组织再发射的光的光谱; 以及利用基于查找表的算法来确定一个或多个组织参数，其中所述基于查找表的算法包括以下步骤：通过测量由所述分光光度计测量的反射率的函数形式来生成查找表，使用一个或多个 具有已知光学性能的更多校准标准; 并且基于查找表来实现迭代拟合例程。

公开(公告)号：US20110176135A1

公开(公告)日：2011-07-21

申请号：US13121712

申请日：2009-10-09

Applicant: Cheung Hoi Albert Yu ,  Lok Ting Lau

Inventor： Cheung Hoi Albert Yu ,  Lok Ting Lau

IPC: G01N21/00 ,  G01N21/59 ,  B82Y15/00

CPC classification number: G01N21/00 ,  G01N21/253 ,  G01N21/554 ,  G01N33/587 ,  G01N2021/258 ,  G01N2021/3185 ,  G01N2201/06146

Abstract: A method for detecting a target analyte associated with nano-sized gold- and/or silver-containing detecting labels in a microarray of samples. The labels indicate presence or absence of a target analyte in a sample. The method includes sequentially illuminating at least two sample groups with at least two different monochromatic light beams. The sample groups include (a) a first sample group containing at least one sample potentially containing the target analyte, and (b) a second sample group serving as positive control or negative control. The method also includes (ii) detecting intensity of light reflected, absorbed, or emitted from each of the sample groups when illuminated with each of the monochromatic light beams. (iii) recording groups of values associated with the intensity reflected, absorbed, or emitted light. (iv) comparing the groups of values associated with the sample groups; and (v) determining the presence of the target analyte based on the comparison.

Abstract translation: 一种用于检测与样品微阵列中的纳米尺寸的含金和/或含银检测标签物相关的目标分析物的方法。 标签表示样品中存在或不存在目标分析物。 该方法包括用至少两个不同的单色光束顺序地照射至少两个样本组。 样品组包括（a）含有至少一种可能含有目标分析物的样品的第一样品组，和（b）用作阳性对照或阴性对照的第二样品组。 该方法还包括（ii）当用每个单色光束照射时，检测从每个样本组反射，吸收或发射的光的强度。 （iii）记录与反射，吸收或发射的光强度相关联的值的组。 （iv）比较与样本组相关的值组; 和（v）基于比较确定目标分析物的存在。

公开(公告)号：US06781695B2

公开(公告)日：2004-08-24

申请号：US09964242

申请日：2001-09-26

Applicant: Richard Hovan ,  Stuart F. Metcalfe ,  Derek D. Stuart

Inventor： Richard Hovan ,  Stuart F. Metcalfe ,  Derek D. Stuart

IPC: G01N2100

CPC classification number: G01N21/59 ,  G01N21/538 ,  G01N21/85 ,  G01N2201/06146

Abstract: An improved light source for use in an opacity monitor (transmissometer) that reduces the variation in light intensity across a projected light beam to enable a more accurate and stable method for measuring the opacity of gases in a stack/duct, especially at low values (e.g.,

Abstract translation: 用于不透明度监测器（透射计）的改进的光源，其减少投影光束的光强度的变化，以便能够更准确和稳定地测量堆/管道中的气体的不透明度，尤其是在低值处 例如，<10％）的不透明度，而在特定的性能要求下运行。

公开(公告)号：US20040150828A1

公开(公告)日：2004-08-05

申请号：US10700086

申请日：2003-11-03

Inventor： James Lee Hendrix ,  David Y. Wang ,  David M. Aikens ,  Lawrence Rotter ,  Joel Ng

IPC: G01J004/00 ,  G01N021/55

CPC classification number: G01J3/02 ,  G01J3/0218 ,  G01J3/10 ,  G01N21/55 ,  G01N21/9501 ,  G01N2201/06146 ,  G01N2201/0826

Abstract: A flat spectrum illumination source for use in optical metrology systems includes a first light source generating a visible light beam and a second light source generating an ultraviolet light beam. The illumination source also includes an auxiliary light source generating a light beam at wavelengths between the visible light beam and the ultraviolet light beam. The three light beams are combined to provide a broadband probe beam that has substantially even illumination levels across a broad range of wavelengths. Alternately, the illumination source may be fabricated as an array of light emitting diodes selected to cover a range of separate wavelengths. The outputs of the LED array are combined to produce the broadband probe beam.

Abstract translation: 用于光学测量系统的平面光谱照明源包括产生可见光束的第一光源和产生紫外光束的第二光源。 照明源还包括在可见光束和紫外光束之间的波长处产生光束的辅助光源。 三个光束被组合以提供在宽范围的波长上具有基本均匀的照明水平的宽带探测光束。 或者，照明源可以被制造为被选择以覆盖一定范围的分开的波长的发光二极管的阵列。 组合LED阵列的输出以产生宽带探测光束。

公开(公告)号：US20030038940A1

公开(公告)日：2003-02-27

申请号：US09964242

申请日：2001-09-26

Inventor： Stuart F. Metcalfe ,  Derek D. Stuart

IPC: G01N021/61

CPC classification number: G01N21/59 ,  G01N21/538 ,  G01N21/85 ,  G01N2201/06146

Abstract: An improved light source for use in an opacity monitor (transmissometer) that reduces the variation in light intensity across a projected light beam to enable a more accurate and stable method for measuring the opacity of gases in a stack/duct, especially at low values (e.g.,

Abstract translation: 用于不透明度监测器（透射计）的改进的光源，其减少投影光束的光强度的变化，以便能够更准确和稳定地测量堆/管道中的气体的不透明度，尤其是在低值处 例如，<10％）的不透明度，而在特定的性能要求下运行。