Method and devices for laser induced fluorescence attenuation spectroscopy (LIFAS)
    82.
    发明授权
    Method and devices for laser induced fluorescence attenuation spectroscopy (LIFAS) 失效
    激光诱导荧光衰减光谱法(LIFAS)的方法和装置

    公开(公告)号:US06697657B1

    公开(公告)日:2004-02-24

    申请号:US09605176

    申请日:2000-06-28

    Abstract: Methods and devices for Laser Induced Fluorescence Attenuation Laser Induced Fluorescence Attenuation Spectroscopy (LIFAS) Spectrocopy, including, in particular, methods and devices for the detection of ischemia and hypoxia in biological tissue. The LIFAS method and apparatus preferably include a source adapted to emit radiation that is directed at a sample volume in a sample to produce return light from the sample, such return light including modulated return light resulting from modulation by the sample, a first sensor, displaced by a first distance from the sample volume for monitoring the return light and generating a first signal indicative of the intensity of return light, a second sensor, displaced by a second distance from the sample volume for monitoring the return light and generating a second signal indicative of the intensity of return light, and a processor associated with the first sensor and the second sensor and adapted to process the first and second signals so as to determine the modulation of the sample. The methods and devices of the inventions are particularly well-suited for determining the wavelength-dependent attenuation of a sample and using the attenuation to restore the intrinsic laser induced fluorescence of the sample. In turn, the attenuation and intrinsic laser induced fluorescence can be used to determined a characteristic of interest, such as the ischemic or hypoxic condition of biological tissue.

    Abstract translation: 激光诱导荧光衰减激光诱导荧光衰减光谱法(LIFAS)的方法和装置,特别是用于检测生物组织缺血和缺氧的方法和装置。 LIFAS方法和装置优选地包括适于发射针对样品中的样品体积的辐射的源,以产生来自样品的返回光,这种返回光包括由样品的调制产生的调制的返回光,第一传感器,位移 距离样品体积的第一距离,用于监测返回光并产生指示返回光强度的第一信号;第二传感器,与样品体积相距离第二距离,用于监测返回光,并产生指示的第二信号 的返回光的强度,以及与第一传感器和第二传感器相关联的处理器并且适于处理第一和第二信号以便确定样本的调制的处理器。 本发明的方法和装置特别适用于确定样品的波长相关衰减,并使用衰减来恢复样品的固有激光诱导荧光。 反过来,衰减和固有的激光诱导荧光可用于确定感兴趣的特征,例如生物组织的缺血或缺氧状况。

    Absorbance modulated fluorescence detection methods and sensors
    83.
    发明授权
    Absorbance modulated fluorescence detection methods and sensors 失效
    吸光度调制荧光检测方法和传感器

    公开(公告)号:US5143853A

    公开(公告)日:1992-09-01

    申请号:US305176

    申请日:1989-02-02

    Applicant: David R. Walt

    Inventor: David R. Walt

    Abstract: A variety of methods and apparatus for the detection of an analyte of interest in a fluid sample is provided which relies upon the interaction of a fluorophore and a chromophoric light absorbing compound for qualitative and quantitative results. The methods preferably employ fiber optic sensors in combination with fluorophores and/or proto-absorber substances in mobile and immobilized modes of use. The methods and apparatus rely upon the ability of the light absorbing compositions to absorb energy which is transferred either radiatively or non-radiatively by the fluorophore when in an excited state.

    Abstract translation: 提供了用于检测流体样品中感兴趣分析物的各种方法和装置,其依赖于荧光团和发色光吸收化合物的相互作用用于定性和定量结果。 该方法优选采用光纤传感器与移动和固定使用模式中的荧光团和/或原吸收物质组合。 所述方法和装置依赖于吸光组合物在处于激发状态时吸收由荧光团辐射或非辐射转移的能量的能力。

    INSPECTION APPARATUS
    86.
    发明申请
    INSPECTION APPARATUS 有权
    检查装置

    公开(公告)号:US20160252461A1

    公开(公告)日:2016-09-01

    申请号:US15033367

    申请日:2014-11-03

    Abstract: An apparatus for inspecting a stream of matter including: a first and a second light source for emitting a first and a second light beam; a first and a second detector; a first scanning element adapted to redirect the detection area of the second detector from side to side across said stream, and a beam splitting element arranged to receive said first and second light beams, after they have been reflected against said matter, wherein said beam splitting element is adapted to guide said reflected first light beam towards said first detector and to guide said reflected second light beam towards said second detector.

    Abstract translation: 一种用于检查物流的装置,包括:用于发射第一和第二光束的第一和第二光源; 第一和第二检测器; 第一扫描元件,其适于将所述第二检测器的检测区域从所述流的一侧到另一侧重定向;以及分束元件,其布置成在它们已经被反射抵靠所述物质之后接收所述第一和第二光束,其中所述光束分裂 元件适于将所述反射的第一光束引向所述第一检测器并且将所述反射的第二光束引导到所述第二检测器。

    METHODS OF DECREASING SCALE IN AQUEOUS SYSTEMS
    87.
    发明申请
    METHODS OF DECREASING SCALE IN AQUEOUS SYSTEMS 有权
    降低水质系统规模的方法

    公开(公告)号:US20160146734A1

    公开(公告)日:2016-05-26

    申请号:US14553113

    申请日:2014-11-25

    Abstract: Water-soluble polymers may be added to an aqueous system to inhibit or decrease scale deposition within the aqueous system. In a non-limiting embodiment, the water-soluble polymer(s) may be or include polymaleates, polyacrylates, copolymers thereof, and combinations thereof. The treated aqueous system may include a decreased amount of scale deposition as compared to an otherwise identical aqueous system absent the water-soluble polymer(s).

    Abstract translation: 可以将水溶性聚合物加入到水性体系中以抑制或减少水性体系内的结垢。 在非限制性实施方案中,水溶性聚合物可以是或包括聚马来酸酯,聚丙烯酸酯,其共聚物,以及它们的组合。 与不存在水溶性聚合物的其它相同的水性体系相比,经处理的水性体系可以包括减少的水垢沉积量。

    Side illuminated multi point multi parameter optical fiber sensor
    88.
    发明授权
    Side illuminated multi point multi parameter optical fiber sensor 有权
    侧面照明多点多参数光纤传感器

    公开(公告)号:US08463083B2

    公开(公告)日:2013-06-11

    申请号:US12697233

    申请日:2010-01-30

    Abstract: A side illuminated multi point multi parameter optical fiber sensor that requires no sensitive coating is provided. This sensor comprises an optical fiber having at least one removed cladding section as the sensitive region, at least one probing light source that side illuminates the fiber, a power supply, a detector, a signal processor and a display. The sensitive optical fiber is optically affected by the presence of a measurand medium that can fluoresce, phosphoresce, absorb and/or scatter the probing light. This probing light is guided by the fiber core towards a detector which measures the light intensity and this light intensity is correlated with a measurand.

    Abstract translation: 提供不需要敏感涂层的侧面照明多点多参数光纤传感器。 该传感器包括具有至少一个去除的包层部分作为敏感区域的光纤,该侧面照射光纤的至少一个探测光源,电源,检测器,信号处理器和显示器。 敏感光纤受到可以荧光,磷光吸收,吸收和/或散射探测光的被测量介质的存在的光学影响。 该探测光由光纤芯引向测量光强度的检测器,该光强度与被测量相关。

    SENSOR AND A METHOD FOR CHARACTERISING A DIELECTRIC MATERIAL
    89.
    发明申请
    SENSOR AND A METHOD FOR CHARACTERISING A DIELECTRIC MATERIAL 审中-公开
    传感器和表征电介质材料的方法

    公开(公告)号:US20130063726A1

    公开(公告)日:2013-03-14

    申请号:US13635276

    申请日:2011-03-11

    Abstract: The present disclosure provides a method of characterising a dielectric material. The method comprises the step of providing a light source, a light collector and a sensor. The sensor is arranged so that an evanescent field of light penetrates through a surface of the sensor and surface plasmons are generated at the surface of the sensor when suitable light is directed along at least a portion of the sensor. The method also includes the step of exposing the surface of the sensor to the dielectric material so that an interface is formed between the surface and the dielectric material. Further, the method comprises guiding light along at least a portion of the sensor to generate the surface plasmons. In addition, the method comprises the step of collecting an intensity of light from the interface as a function of a spectral parameter of the light. Further, the present disclosure provides an apparatus for characterising the dielectric material in accordance with the method.

    Abstract translation: 本公开提供了表征电介质材料的方法。 该方法包括提供光源,集光器和传感器的步骤。 传感器布置成使得消逝的光线穿过传感器的表面,并且当合适的光沿着传感器的至少一部分被引导时,在传感器的表面处产生表面等离子体激元。 该方法还包括将传感器的表面暴露于介电材料的步骤,使得在表面和电介质材料之间形成界面。 此外,该方法包括沿着传感器的至少一部分引导光以产生表面等离子体激元。 此外,该方法包括作为光的光谱参数的函数从界面收集光强度的步骤。 此外,本公开提供了一种根据该方法表征电介质材料的装置。

    Measuring system and measuring method, in particular for determining blood glucose
    90.
    发明授权
    Measuring system and measuring method, in particular for determining blood glucose 有权
    测量系统和测量方法,特别是用于测定血糖

    公开(公告)号:US08373851B2

    公开(公告)日:2013-02-12

    申请号:US13540001

    申请日:2012-07-02

    Abstract: A measuring system for determining blood glucose includes a photometric measuring unit with a light source and a detector, and an analytical test element, to which a body fluid sample can be applied, and which can be placed in a beam path between the light source and the detector for optical detection of an analyte. For an improved multi-wavelength measurement, it is proposed that the light source includes a first emitter that can be actuated in a first wavelength range to emit pulsating alternating light and a second emitter that can be excited in a second wavelength range to emit fluorescent light.

    Abstract translation: 一种用于测定血糖的测量系统包括具有光源和检测器的测光单元以及能够施加体液样品的分析测试元件,并且其可以放置在光源和 用于光学检测分析物的检测器。 对于改进的多波长测量,提出了光源包括能够在第一波长范围内致动以发射脉动交替光的第一发射器和可在第二波长范围内被激发以发射荧光的第二发射极 。

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