公开(公告)号：EP3055433A4

公开(公告)日：2017-05-03

申请号：EP14851985

申请日：2014-10-09

Applicant: UNIV ROCHESTER ,  UAB RES FOUND

Inventor： MILLER BENJAMIN L ,  NAHM MOON H

IPC: G01N33/569 ,  G01N21/21 ,  G01N21/55 ,  G01N33/543

CPC classification number: G01N33/56944 ,  G01N21/211 ,  G01N21/55 ,  G01N33/54373 ,  G01N2201/06113 ,  G01N2201/0683 ,  G01N2333/3156

Abstract: According to aspects illustrated herein, there are provided a sensor chip suitable for serological detection of Streptococcus pneumoniae, a method for detecting serotypes of Streptococcus pneumoniae using the sensor chip, a detection system that includes the sensor chip, and a method for detecting serotypes of Streptococcus pneumoniae using the detection system described herein.

Abstract translation: 根据本文所示的方面，提供了一种适用于肺炎链球菌血清学检测的传感器芯片，一种使用传感器芯片检测肺炎链球菌血清型的方法，一种包括传感器芯片的检测系统以及一种用于检测链球菌血清型的方法 使用本文所述的检测系统进行肺炎。

公开(公告)号：EP2993460A4

公开(公告)日：2017-04-26

申请号：EP14804538

申请日：2014-05-30

Applicant: UNIV OSAKA PREFECT PUBLIC CORP

Inventor： IIDA TAKUYA ,  TOKONAMI SHIHO

IPC: G01N21/17 ,  C12Q1/68 ,  G01N21/3577 ,  G01N21/41 ,  G01N21/552 ,  G01N21/65 ,  G01N33/53 ,  G01N33/543 ,  G01N33/553

CPC classification number: G01N33/54346 ,  C12Q1/6834 ,  C12Q2563/155 ,  C12Q2565/628 ,  G01N21/21 ,  G01N21/554 ,  G01N21/658 ,  G01N33/5308 ,  G01N33/553 ,  G01N2201/061 ,  G01N2201/0683

Abstract: A detection device (100) detects an analyte that may be contained in a specimen. The detection device (100) includes a plurality of gold nanoparticles, an optical trapping light source (101), an illumination light source (102), an objective lens (103), an image pick-up device (108), and a computation unit (106). The plurality of gold nanoparticles are each modified with a probe DNA allowing the analyte to specifically adhere thereto. The optical trapping light source (101) emits polarized light for assembling the plurality of gold nanoparticles together. The objective lens (103) focuses and introduces the polarized light into a liquid containing a specimen and the plurality of gold nanoparticles. The image pick-up device (108) receives light from the liquid. The computation unit (106) detects an analyte based on a signal received from the image pick-up device (108).

Abstract translation: 检测装置（100）检测可能包含在样本中的分析物。 检测装置（100）包括多个金纳米粒子，光俘获光源（101），照明光源（102），物镜（103），图像拾取装置（108）和计算机 单元（106）。 多个金纳米颗粒各自用允许分析物特异性粘附于其上的探针DNA修饰。 光俘获光源（101）发射用于将多个金纳米颗粒组装在一起的偏振光。 物镜（103）聚焦并将偏振光引入含有样本和多个金纳米颗粒的液体中。 图像拾取装置（108）接收来自液体的光。 计算单元（106）基于从图像拾取装置（108）接收的信号来检测分析物。

公开(公告)号：EP3149451A1

公开(公告)日：2017-04-05

申请号：EP15727049.7

申请日：2015-05-28

Applicant: The University Of Birmingham

Inventor： DAFFORN, Timothy ,  HICKS, Matthew

IPC: G01N21/05 ,  G01N21/19 ,  G01N21/21 ,  C12Q1/68

CPC classification number: G01N21/19 ,  C12Q1/6825 ,  G01N21/05 ,  G01N21/21 ,  G01N33/56916 ,  G01N2201/061 ,  G01N2201/0683 ,  G01N2333/245 ,  G01N2333/255 ,  G01N2469/10 ,  C12Q2563/107

Abstract: A molecular sensor that utilises dichroism can be used to identify the presence of specific molecules in a substance. The molecular sensor includes a sensor element comprising (i) a scaffold moiety and (ii) one or more receptor molecules for the target molecule attached to the scaffold moiety to form a scaffold/receptor complex, wherein the scaffold/receptor complex is modified to incorporate a chromophore and the modified scaffold/receptor complex has a high aspect ratio.

Abstract translation: 利用二色性的分子传感器可用于识别物质中特定分子的存在。 分子传感器包括传感器元件，其包括（i）支架部分和（ii）用于靶分子的一个或多个受体分子，所述受体分子连接到所述支架部分以形成支架/受体复合物，其中所述支架/受体复合体被修饰为掺入 发色团和修饰的支架/受体复合物具有高的纵横比。

公开(公告)号：EP3081163A2

公开(公告)日：2016-10-19

申请号：EP16164562.7

申请日：2016-04-08

Applicant: Taiwan Biophotonic Corporation

Inventor： LI, YU-TANG ,  CHU, CHANG-SHENG ,  HO, KUAN-JUI ,  HO, PEI-CHENG ,  CHUNG, SHUANG-CHAO ,  FAN, CHIH-HSUN ,  CHEN, JYH-CHERN

IPC: A61B5/145 ,  A61B5/1455 ,  A61B5/00 ,  A61B3/10

CPC classification number: G01N21/21 ,  A61B3/10 ,  A61B3/152 ,  A61B5/1455 ,  G01B11/272 ,  G01N33/483 ,  G01N2201/0633 ,  G01N2201/0683 ,  G01N2201/126

Abstract: The present disclosure generally relates to an optical measurement module, an optical measurement device, and a method for optical measurement. The optical measurement module provides optical architecture to measure the optical properties of an analyte. The optical measurement device comprising the optical measurement module is configured to measure the optical properties of an analyte. The method for the optical measurement provides steps for optical measurement.

公开(公告)号：EP3055433A1

公开(公告)日：2016-08-17

申请号：EP14851985.3

申请日：2014-10-09

Applicant: University of Rochester ,  The UAB Research Foundation

Inventor： MILLER, Benjamin, L. ,  NAHM, Moon, H.

IPC: C12Q1/70

CPC classification number: G01N33/56944 ,  G01N21/211 ,  G01N21/55 ,  G01N33/54373 ,  G01N2201/06113 ,  G01N2201/0683 ,  G01N2333/3156

Abstract: According to aspects illustrated herein, there are provided a sensor chip suitable for serological detection of Streptococcus pneumoniae, a method for detecting serotypes of Streptococcus pneumoniae using the sensor chip, a detection system that includes the sensor chip, and a method for detecting serotypes of Streptococcus pneumoniae using the detection system described herein.

Abstract translation: 根据本文所述的方面，提供了适用于肺炎链球菌的血清学检测的传感器芯片，使用传感器芯片检测肺炎链球菌血清型的方法，包括传感器芯片的检测系统和检测链球菌血清型的方法 使用本文所述的检测系统的肺炎链球菌。

公开(公告)号：EP3042239A1

公开(公告)日：2016-07-13

申请号：EP14758923.8

申请日：2014-09-03

Applicant: Leica Microsystems CMS GmbH

Inventor： KRISHNAMACHARI, Vishnu Vardhan

IPC: G02B27/28 ,  G02B21/00

CPC classification number: G01N21/21 ,  G01N21/65 ,  G01N2201/067 ,  G01N2201/0683 ,  G02B21/002 ,  G02B21/0032 ,  G02B21/0068 ,  G02B27/283 ,  G02B27/286

Abstract: The invention relates to a method for examining a sample, the sample being subjected to illumination light and detection light coming from the sample being directed to a detector, and the illumination light being directed through an acousto-optical component with which the sample can be temporarily interrupted from being subjected to illumination light. The method is characterized in that the sample is illuminated by a first illumination light bundle that has a first linear polarization direction and by a second illumination light bundle, the linear polarization direction of which is continuously switched between the first linear polarization direction and a second linear polarization direction that is different from the first linear polarization direction. The illumination light of the first linear polarization direction runs along a first light path and the illumination light of the second linear polarization direction runs along a second light path, and the acousto-optical component unites the light paths.

公开(公告)号：EP2909624A4

公开(公告)日：2016-06-08

申请号：EP13846901

申请日：2013-10-16

Applicant: SCIENCES GP LLC K

Inventor： KORMAN VALENTIN

IPC: G01N33/48 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/21

CPC classification number: A61B5/14532 ,  A61B5/1455 ,  A61B5/14558 ,  A61B5/6815 ,  A61B5/7225 ,  A61B2560/0443 ,  A61B2562/0238 ,  G01N21/21 ,  G01N2201/062 ,  G01N2201/0683

Abstract: A glucose sensor comprising an optical energy source having an emitter with an emission pattern; a first polarizer intersecting the emission pattern; a second polarizer spaced a distance from the first polarizer and intersecting the emission pattern, the second polarizer rotated relative to the first polarizer by a first rotational amount Θ; a first optical detector intersecting the emission pattern; a second optical detector positioned proximal to the second polarizer, the first polarizer and the second polarizer being positioned between the optical energy source and the second optical detector, the second optical detector intersecting the emission pattern; a compensating circuit coupled to the second optical detector; and a subtractor circuit coupled to the compensating circuit and the first optical detector.

公开(公告)号：EP2889603A4

公开(公告)日：2016-04-20

申请号：EP13846617

申请日：2013-08-30

Applicant: SONY CORP

Inventor： TAKEUCHI TAICHI ,  IMANISHI SHINGO

IPC: G01N15/14

CPC classification number: G01N15/1436 ,  G01N15/1429 ,  G01N15/1434 ,  G01N15/1459 ,  G01N21/21 ,  G01N21/47 ,  G01N21/49 ,  G01N21/53 ,  G01N21/645 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2021/6478 ,  G01N2201/06113 ,  G01N2201/0638 ,  G01N2201/0683

Abstract: A microparticle measuring apparatus for highly accurately detecting the position of a microparticle flowing through a flow channel includes a light irradiation unit for irradiating a microparticle flowing through a flow channel with light, and a scattered light detection unit for detecting scattered light from the microparticle, including an objective lens for collecting light from the microparticle, a light splitting element for dividing the scattered light from the light collected by the objective lens, into first and second scattered light, a first scattered light detector for receiving an S-polarized light component, and an astigmatic element disposed between the light splitting element and the first scattered light detector, and making the first scattered light astigmatic. A relationship between a length L from a rear principal point of the objective lens to a front principal point of the astigmatic element, and a focal length f of the astigmatic element satisfies the following formula I. 1.5 �¢ f ‰¤ L ‰¤ 2.5 �¢ f

公开(公告)号：EP2963627A1

公开(公告)日：2016-01-06

申请号：EP14175734.4

申请日：2014-07-04

Applicant: Amrona AG

Inventor： Siemens, Andreas

IPC: G08B17/107 ,  G01N30/74 ,  G01N21/03

CPC classification number: G01N21/53 ,  G01N2021/473 ,  G01N2201/062 ,  G01N2201/0642 ,  G01N2201/0683 ,  G08B17/107 ,  G08B17/113

Abstract: Es wird eine Anordnung (100) zum Abschwächen auftreffenden Lichts eines Strahlenbündels mit endlicher Aufweitung angegeben. Mit dem Ziel, eine zuverlässige Abschwächung insbesondere direkt auftreffenden Lichts zu erzielen, sieht die erfindungsgemäße Lösung vor, dass die Anordnung eine Lichtquelle (10) zum Erzeugen eines Lichtbündels unpolarisierten Lichts, vorzugsweise unpolarisierten monochromatischen Lichts, einen Nutzlichtbereich (50), den das unpolarisierte Licht durchläuft und vorzugsweise ausgehend von der Lichtquelle (10) geradlinig durchläuft sowie eine dem Nutzlichtbereich (50) nachgeordnete und vorzugsweise in direkter Strahlrichtung des Lichtbündels nachgeordneter Absorptionseinrichtung (30) zum zumindest teilweisen Absorbieren auftreffenden Lichts aufweist, wobei die Absorptionseinrichtung (30) mindestens eine in Richtung des Lichtbündels angeordnete Polarisationseinrichtung (31, 32) aufweist.

Abstract translation: 提供了一种用于衰减有限扩张的光束的入射光的组件（100）。 以实现与一个可靠衰减特定直接入射光，本发明的解决方案提供了，所述装置包括用于产生非偏振光的光束的光源（10），优选非偏振单色光，一个Nutzlichtbereich（50）与所述非偏振光的目的 通行证，并且优选地，从光源开始（10）穿过的直线以及在直接光束的光束方向上的所述Nutzlichtbereich（50）的下游，并且优选下游吸收装置（30）用于至少部分地吸收入射光，所述吸收装置（30）的至少一个方向 的光偏振装置的布置光束（31，32）。

公开(公告)号：EP2205949A1

公开(公告)日：2010-07-14

申请号：EP08845082.0

申请日：2008-11-03

Applicant: Deka Products Limited Partnership

Inventor： HELMORE, Simon, C. ,  SACHS, Jason ,  SCARPACI, Jacob, W.

IPC: G01J4/00

CPC classification number: G01N21/21 ,  A61M1/14 ,  G01J4/04 ,  G01N21/90 ,  G01N2201/0612 ,  G01N2201/0683

Abstract: Methods and apparatus for concentration determination using polarized light. The apparatus includes a first polarized light source having a first light source polarization axis and a second polarized light source having a second light source polarization axis generally perpendicular to the first light source polarization axis. Also, a first polarized light receiver having a first polarized light receiver polarization axis and configured to measure an intensity of light transmitted from the first light receiver polarizer and a second polarized light receiver having a second polarized light receiver polarization axis substantially perpendicular to the first light receiver polarization axis and configured to measure an intensity of light transmitted from the second light receiver polarizer, wherein the first and second light receiver polarization axes are generally +/−45 degrees relative to the first and second light source polarization axes.