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公开(公告)号：WO2009119993A2
公开(公告)日：2009-10-01
申请号：PCT/KR2009/001408
申请日：2009-03-19
CPC classification number: G01N33/558 , G01N30/92
Abstract: 본 발명은 면역분석에 사용되는 면역 크로마토그래피 스트립을 내장한 면역 크로마토그래피 키트 및 그 제조방법을 개시한다. 본 발명은 면역 크로마토그래피 스트립; 투명 플라스틱 재질로 만들어지고, 상기 면역 크로마토그래피 스트립을 수용하도록 상기 검체 패드 및 상기 컨쥬케이트 패드 부분을 수용할 수 있도록 형성되는 일측의 검체 패드 수용부와, 상기 흡수 패드 부분을 수용할 수 있도록 형성되는 다른 일측의 흡수 패드 수용부, 및 상기 신호검출 패드 부분을 수용하도록 형성되는 검체 패드 수용부와 흡수 패드 수용부 사이의 신호검출 패드 수용부를 포함하는 면역 크로마토그래피 스트립 수용공간을 구비하며, 검체 패드 수용부와 통하도록 관통 형성되어 상기 검체 패드 상부에 위치하게 되며 분석을 위해 투입될 액상 검체를 상기 검체 패드로 유도하도록 둘레 부분이 깔때기 형상으로 형성되는 투입구, 및 흡수 패드 수용부가 통하도록 관통 형성되어 상기 흡수 패드 상부에 위치하게 되는 하나 이상의 통기구를 구비하는 커버; 및 상기 면역 크로마토그래피 스트립 수용공간을 폐쇄하도록 상기 커버의 바닥측에 부착되는 밑판;을 포함하는 것을 특징으로 하는 면역 크로마토그래피 키트 및 그 제조방법을 제공한다.
Abstract translation: 本发明公开了免疫色谱试剂盒，其包含用于免疫测定的免疫色谱条及其生产方法。 本发明涉及一种免疫色谱条; 样品垫容纳部分，其由透明塑料材料制成，并被配置为容纳所述样品垫和所述结合垫部分以容纳所述免疫色谱条; 接收在所述另一侧部的吸收垫，并包含含有信号检测垫信号检测样品垫接纳部之间接收部分被形成为接收所述焊盘部分和所述吸收垫接纳部的免疫色谱条容纳空间，样品垫接收 并且吸收垫容纳部分形成为穿过吸收垫容纳部分以穿过吸收垫容纳部分，吸收垫容纳部分与吸收垫容纳部分连通， 一个或多个“ 具有机构罩; 并且，为了封闭用于容纳免疫色谱法试片的空间而安装在盖的底面上的基板以及免疫层析试剂盒的制造方法。
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公开(公告)号：KR1020090101823A
公开(公告)日：2009-09-29
申请号：KR1020090017090
申请日：2009-02-27
Applicant: (주)래피젠
Abstract: PURPOSE: An immunochromatographic kit and a method for manufacturing the same are provided to be suitable for mass production through automation of a process and to reduce production costs. CONSTITUTION: An immunochromatography kit contains an immunochromatographic strip(100), a cover, and a bottom plate(300) which is attached to the bottom side of the cover to enclose an immunochromatographic strip housing. The cover comprises: the immunochromatographic strip housing; a funnel-shaped inlet port(215) which is located on the upper side of a sample pad that is connected to a sample pad housing unit and which channels a liquid sample to the detection pad for analysis; and one or more holes(225) which are located on the upper side of an absorption pad to be connected to an absorption pad housing unit. The transparent plastic immunochromatographic strip housing comprises: the sample pad housing unit on one end of the immunochromatographic strip to contain the sample pad and a conjugate pad; the absorption pad housing unit on the other end of the immunochromatographic strip; and a signal detection pad housing unit between the sample pad housing unit and absorption pad housing unit.
Abstract translation: 目的：提供免疫色谱试剂盒及其制造方法，适用于通过工艺自动化进行批量生产并降低生产成本。 构成：免疫色谱试剂盒含有免疫色谱条（100），盖和底板（300），其连接到盖的底侧以包围免疫层析条带外壳。 盖子包括：免疫层析条带外壳; 漏斗形入口（215），其位于样品垫的上侧，其连接到样品垫容纳单元，并将液体样品通道到检测垫进行分析; 以及位于吸收垫的上侧以连接到吸收垫容纳单元的一个或多个孔（225）。 透明塑料免疫层析条外壳包括：在免疫色谱条的一端上的样品垫容纳单元，以容纳样品垫和共轭垫; 所述吸收垫容纳单元位于所述免疫色谱条的另一端; 以及信号检测垫容纳单元，位于样品垫容纳单元和吸收垫容纳单元之间。
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Patent Agency Ranking
公开(公告)号：KR100735080B1
公开(公告)日：2007-07-03
申请号：KR1020060073460
申请日：2006-08-03
Applicant: (주)래피젠
Inventor： 박재구
IPC: G01N30/00
CPC classification number: G01N33/558
Abstract: Provided is an immunochromatographic strip for immunoassay, which absorbs a liquid subject material efficiently to facilitate chromatographic work, prevents errors caused by counterflow of a liquid subject material, and enhances background clearance. The immunochromatographic strip(100) comprises: (a) an adhesive plastic support(101); (b) a pad(201) for receiving a liquid subject material to be analyzed, wherein the pad is attached to the top surface of the support; (c) a conjugate pad(202) communicating with the pad for the subject material, and comprising a conjugate bound specifically to an analyte contained in the liquid subject material through the pad for the subject material; (d) a signal detection pad(203) comprising a signal detection region(203a) for detecting whether the analyte exists in the liquid subject material or not, and a comparing region(203b) for determining whether the liquid subject material chromatographically moves or not regardless of the presence of the analyte; and (e) an absorption pad(300) for absorbing the liquid subject material after the completion of the signal detection, wherein the absorption pad is positioned in the downstream of the signal detection pad. In the immunochromatographic strip, the absorption pad comprises a porous support(310), and an absorbing agent(320) dispersed in pores of the porous support or adsorbed or coated on the fibers of the porous support.
Abstract translation: 本发明提供了一种免疫测定用免疫层析条，其有效吸收液体受试材料以促进色谱工作，防止液体主体材料逆流引起的错误，并提高背景清除率。 免疫色谱条（100）包括：（a）粘合剂塑料支撑体（101）; （b）用于接收待分析的液体主体材料的焊盘（201），其中所述焊盘附接到所述支撑件的顶表面; （c）与主体材料的垫连通的共轭垫（202），并且包括通过用于所述主题材料的所述垫的与所述液体主体材料中包含的分析物特异性结合的共轭体; （d）信号检测焊盘（203），包括用于检测分析物是否存在于液体主题材料中的信号检测区域（203a），以及用于确定液体主题材料是否具有色谱运动的比较区域（203b） 不管分析物的存在; 和（e）用于在完成信号检测之后吸收液体主体材料的吸收垫（300），其中吸收垫位于信号检测垫的下游。 在免疫层析条中，吸收垫包括多孔载体（310）和分散在多孔载体的孔中或吸附或涂覆在多孔载体的纤维上的吸收剂（320）。
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公开(公告)号：KR101332336B1
公开(公告)日：2013-11-22
申请号：KR1020130051361
申请日：2013-05-07
Applicant: (주)래피젠
Inventor： 박재구
CPC classification number: G01N33/558 , G01N2333/11 , G01N2333/186 , G01N2333/20 , G01N2333/295 , G01N2333/445 , Y02A50/52 , Y02A50/53 , Y02A50/58 , Y02A50/59
Abstract: The present invention relates to an immunochromatography analysis strip and a kit containing the strip. The immunochromatography analysis strip and the kit containing the strip comprise: a) an adhesive plastic support member; b) a sample pad arranged on the upper surface of the adhesive plastic support member from an upper region to a lower region and equipped with a buffer inlet part in the upper region and a sample inlet part in the lower region to receive a liquid sample to be analyzed; c) a conjugate pad, for containing a conjugate to be specifically bonded to the analytes contained in the liquid sample of the sample pad, which is placed in a lower direction of the lower region of the sample pad; d) a signal detection pad, placed adjacent to the conjugate pad in the lower end of the conjugate pad, which contains a signal detection part for detecting analytes in the liquid sample and a control part to confirm the transfer of the liquid sample to the absorbing pad; and e) an immunochromatographic strip containing the absorbing pad placed adjacent to the signal detection pad in the lower end of the signal detection pad; and further comprises a control tape placed between the sample inlet part of the sample pad and the conjugate pad based on a material which prevents the pass of the liquid sample. Furthermore, the immunochromatography analysis strip and the kit containing the strip are provided to control the amount of analytes for analysis after transferring the sample injected according to the overlapped length of the conjugate pad and the control tape to the conjugate pad.
Abstract translation: 本发明涉及免疫色谱分析条和含有该条的试剂盒。 免疫色谱分析条和包含条的试剂盒包括：a）粘合剂塑料支撑构件; b）从上部区域到下部区域布置在粘合剂塑料支撑构件的上表面上并且在上部区域中配备有缓冲入口部分的样品垫和在下部区域中的样品入口部分以接收液体样品 分析; c）共轭垫，用于包含特定结合到样品垫的液体样品中的分析物的共轭物，其被放置在样品垫的下部区域的下方; d）信号检测垫，放置在所述共轭垫的下端中与所述共轭垫相邻的位置，所述信号检测垫包含用于检测所述液体样品中的分析物的信号检测部分和用于确认液体样品向所述吸收物质的转移的控制部分 垫; 以及e）包含与所述信号检测垫的下端中的信号检测垫相邻放置的吸收垫的免疫色谱条; 并且还包括基于防止液体样品通过的材料而放置在样品垫的样品入口部分和缀合物垫之间的控制带。 此外，提供免疫色谱分析条和含有条带的试剂盒，以根据共轭垫和控制带的重叠长度将注入的样品转移到缀合垫后，控制用于分析的分析物的量。
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公开(公告)号：KR100995291B1
公开(公告)日：2010-11-19
申请号：KR1020080013557
申请日：2008-02-14
Applicant: 대한민국(농림축산식품부 농림축산검역본부장) , (주)래피젠
IPC: G01N33/50 , G01N30/02 , G01N33/68 , G01N33/543
Abstract: 본 발명은 면역크로마토그래피를 이용한 네오스포라병의 진단 키트에 관한 것이다. 보다 구체적으로는, 세포 배양된 국내 분리주 네오스포라 원충의 항원을 이용하여 면역크로마토그래피법을 이용한 혈청학적 진단법에 관한 것으로, 본 발명에 따르면, 막에 항원을 결합시킨 후 가검 혈청과의 반응여부를 육안적으로 관찰하여 판단하기 때문에, 본 발명에 의해 고가의 장비를 필요로 하지 않는 간편하고 경제적 진단법을 제공할 수 있다.
소, 유·사산, 네오스포라병, 면역크로마토그래피, 진단방법-
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公开(公告)号：KR1020090088169A
公开(公告)日：2009-08-19
申请号：KR1020080013557
申请日：2008-02-14
Applicant: 대한민국(농림축산식품부 농림축산검역본부장) , (주)래피젠
IPC: G01N33/50 , G01N30/02 , G01N33/68 , G01N33/543
Abstract: A diagnosis kit of neosporosis using immunochromatography is provided to simply and economically diagnose neosporosis without expensive equipment. A diagnosis kit using immunochromatography comprises a neospora canium antigen which is adhered on a film. The antigen is Neospora caninum Kr2 strain. The film is a nitrocellulose film. The diagnosis further comprises anti-bovine immunoglobulin G on the film.
Abstract translation: 提供使用免疫色谱法的新孢子虫病诊断试剂盒，用于简单且经济地诊断新孢子虫病，无需昂贵的设备。 使用免疫色谱法的诊断试剂盒包括粘附在膜上的新孢子虫抗原。 抗原是新孢子虫Kr2株。 该膜是硝酸纤维素膜。 该诊断还包括抗牛免疫球蛋白G。
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