歯周病菌増殖抑制用組成物
    4.
    发明专利

    公开(公告)号:JP2019094269A

    公开(公告)日:2019-06-20

    申请号:JP2017222116

    申请日:2017-11-17

    Abstract: 【課題】優れた歯周病菌増殖抑制作用を発揮する歯周病菌増殖抑制用組成物を提供する。【解決手段】本発明の歯周病菌増殖抑制用組成物は、アルテピリンC、バッカリン、ドルパニン等の桂皮酸誘導体を有効成分として含有する。かかる組成物は、ポルフィロモナス(Porphyromonas)属等の歯周病菌の増殖を抑制して、歯周病、歯周炎、歯槽膿漏、歯肉炎、歯垢の沈着、歯石の沈着、及び口臭から選ばれる少なくとも一種の症状の改善、緩和若しくは予防、又は口腔内衛生の維持若しくは増進のために好ましく用いられる。【選択図】なし

    動物用患部保護材及び忌避剤
    5.
    发明专利

    公开(公告)号:JP2019025041A

    公开(公告)日:2019-02-21

    申请号:JP2017148142

    申请日:2017-07-31

    Abstract: 【課題】保護材で被覆された患部を容易に保護することができる動物用患部保護材及び忌避剤を提供する。【解決手段】本発明の動物用患部保護材は、プロポリス原塊又はその抽出物が付着していることを特徴とする。前記抽出物は、プロポリス原塊に水を加えて得られた不溶性残渣に、さらに親水性有機溶媒又は含水親水性有機溶媒を加えて得られた可溶性画分が用いられてもよい。また、本発明の忌避剤は、動物用患部保護材に付着させて使用され、プロポリス原塊又はその抽出物を含有することを特徴とする。【選択図】なし

    Royal jelly-containing tablet and method for manufacturing the same
    6.
    发明专利
    Royal jelly-containing tablet and method for manufacturing the same 有权
    皇家果仁花瓶及其制造方法

    公开(公告)号:JP2014150782A

    公开(公告)日:2014-08-25

    申请号:JP2013025612

    申请日:2013-02-13

    Abstract: PROBLEM TO BE SOLVED: To provide, by targeting a tablet including royal jelly as a main component, a royal jelly-containing tablet capable of enhancing the hardness of the tablet; and a method for manufacturing the same.SOLUTION: The royal jelly-containing tablet of the present invention includes royal jelly as a main component and is obtained by performing a process of wet-compressing, at 10 MPa or above, a royal jelly provided as a raw ingredient of the royal jelly-containing tablet. It is desirable for the hardness of the royal jelly-containing tablet to be 80 N or higher. Moreover, it is also permissible to obtain a coated royal jelly-containing tablet by performing a process of coating the surface of the tablet obtained by such a method.

    Abstract translation: 要解决的问题:通过以包含蜂王浆为主要成分的片剂,可以提供能够提高片剂硬度的含蜂胶的片剂, 及其制造方法。解决方案:本发明的含蜂胶的片剂包括蜂王浆作为主要成分,并且通过在10MPa或更高的压力下进行湿法压缩而获得的蜂王浆作为 蜂王浆含有片剂的原料。 希望含有蜂王浆的片剂的硬度为80N以上。 此外,还可以通过进行涂布通过这种方法得到的片剂的表面的方法来获得包覆的含有蜂王浆的片剂。

    Sterile refining apparatus for active pharmaceutical ingredients
    7.
    发明专利
    Sterile refining apparatus for active pharmaceutical ingredients 有权
    用于活性药物成分的纯化精制装置

    公开(公告)号:JP2013031626A

    公开(公告)日:2013-02-14

    申请号:JP2011258077

    申请日:2011-11-25

    CPC classification number: B65B55/12

    Abstract: PROBLEM TO BE SOLVED: To provide a sterile refining apparatus for active pharmaceutical ingredients, the apparatus being able to further reduce the content of impurities.SOLUTION: The sterile refining apparatus for active pharmaceutical ingredients is used for performing a first step in which after a solution of pharmaceutical crude ingredients is prepared by dissolving pharmaceutical crude ingredients in a first solution, the prepared solution is sterilized, a second step in which the pharmaceutical ingredients is crystallized by adding an aseptically filtered second solvent to the sterile prepared solution, and a third step in which the crystallized pharmaceutical ingredients is filtered, dried, and pulverized, and the thus obtained powder of pharmaceutical ingredients is filled into a container. In the sterile refining apparatus, the steps are connected by pipes from a pharmaceutical crude ingredients input part to a container filling device 39 in order to carry out the steps under inert gas atmosphere by use of a series of inline systems. The pharmaceutical ingredients are filtered and dried in the third step is conveyed out from a conveyance port by inert gas flowing downstream from a filtering dryer, is conveyed to a powder transport hopper 31, located below the filtering dryer, by a vibration feeder 29, and is conveyed to a pulverizing device 36 by a screw conveyer.

    Abstract translation: 要解决的问题:为了提供用于活性药物成分的无菌精制装置,该装置能够进一步降低杂质含量。 解决方案:用于活性药物成分的无菌精制装置用于进行第一步骤,其中通过将药物粗成分溶解在第一溶液中制备药物粗制成分溶液后,将制备的溶液灭菌,第二步骤 其中通过向无菌制备的溶液中加入无菌过滤的第二溶剂使药物成分结晶,并且将结晶的药物成分过滤,干燥和粉碎的第三步骤,将由此获得的药物成分粉末填充到 容器。 在无菌精制装置中,通过管道从药物原料输入部分连接到容器填充装置39,以便通过使用一系列在线系统在惰性气体气氛下进行步骤。 将第三步骤中的药物成分过滤并干燥,通过从过滤干燥器下游流动的惰性气体从输送口输送,通过振动给料器29输送到位于过滤干燥器下方的粉末输送料斗31,以及 通过螺旋输送机输送到粉碎装置36。 版权所有(C)2013,JPO&INPIT

    Skin fibroblast proliferation-promoting agent and skin collagen production-promoting agent
    8.
    发明专利
    Skin fibroblast proliferation-promoting agent and skin collagen production-promoting agent 有权
    皮肤成纤维细胞增殖促进剂和皮肤胶原蛋白生产促进剂

    公开(公告)号:JP2012056890A

    公开(公告)日:2012-03-22

    申请号:JP2010202061

    申请日:2010-09-09

    Abstract: PROBLEM TO BE SOLVED: To provide a skin fibroblast proliferation-promoting agent and a skin collagen production-promoting agent each capable of being utilized for various uses such as cosmetics, foods, drinks and medicines.SOLUTION: The skin fibroblast proliferation-promoting agent and the skin collagen production-promoting agent each contains apisin as an active ingredient. Preferably, the apisin is separated from royal jelly by liquid chromatography.

    Abstract translation: 待解决的问题:提供能够用于化妆品,食品,饮料和药物等各种用途的皮肤成纤维细胞增殖促进剂和皮肤胶原蛋白生产促进剂。 皮肤成纤维细胞增殖促进剂和皮肤胶原蛋白生成促进剂各自含有作为活性成分的脱乙酰壳多糖。 优选地,通过液相色谱法将蜂毒素与蜂王浆分离。 版权所有(C)2012,JPO&INPIT

    Royal jelly-containing composition
    9.
    发明专利
    Royal jelly-containing composition 审中-公开
    皇家含糖组合物

    公开(公告)号:JP2011152103A

    公开(公告)日:2011-08-11

    申请号:JP2010016885

    申请日:2010-01-28

    Abstract: PROBLEM TO BE SOLVED: To provide a royal jelly-containing composition prevented from discoloration of outer appearance with age in solid royal jelly. SOLUTION: The royal jelly-containing composition is obtained by dissolving in a solvent, royal jelly and at least one kind selected from starch, and dextrin having a dextrose equivalent of not more than 18, and freeze-drying the product. It is preferable to use starch, and dextrin having a dextrose equivalent of not more than 3. COPYRIGHT: (C)2011,JPO&INPIT

    Abstract translation: 待解决的问题:提供一种含有蜂王浆的组合物,防止在固体蜂王浆中随着年龄的变化而变色。 解决方案:含有蜂王浆的组合物通过溶解在溶剂,蜂王浆和选自淀粉中的至少一种和葡萄糖当量不超过18的糊精中,并将产物冷冻干燥而获得。 优选使用淀粉和葡萄糖当量不超过3的糊精。版权所有(C)2011,JPO&INPIT

    Method for producing retusapurpurin a extracted from red propolis raw mass, and method for assessing red propolis extract using the retusapurpurin a
    10.
    发明专利
    Method for producing retusapurpurin a extracted from red propolis raw mass, and method for assessing red propolis extract using the retusapurpurin a 有权
    用于生产从红色丙酸纤维素提取的回肠胃蛋白酶的方法,以及使用回肠肽素A评估红细胞提取物的方法

    公开(公告)号:JP2011050376A

    公开(公告)日:2011-03-17

    申请号:JP2010159057

    申请日:2010-07-13

    Abstract: PROBLEM TO BE SOLVED: To provide a method for producing retusapurpurin A applicable to the sectors of e.g. food/drink and cosmetics, etc., and to provide a method for assessing propolis extracts. SOLUTION: The method for producing retusapurpurin A includes: the step of conducting an extract treatment, using an extractive solvent, from propolis raw mass made from raw material Dalbergia as the original plant. The method for assessing a propolis extract obtained using an extractive solvent, from propolis raw mass made from raw material Dalbergia as the original plant is characterized in comprising using retusapurpurin A as an indicator. COPYRIGHT: (C)2011,JPO&INPIT

    Abstract translation: 解决问题的方法:提供一种制造适用于例如上述的扇贝的视网膜素A的方法。 食品/饮料和化妆品等,并提供蜂胶提取物的评估方法。 解决方案:产生retusperururur A的方法包括:使用由原料Dalbergia制成的蜂胶原料作为原始植物,使用萃取溶剂进行提取处理的步骤。 使用由原料Dalbergia制成的蜂胶原料作为原始植物,使用萃取溶剂获得的蜂胶提取物的方法的特征在于包括使用retusperururur A作为指示剂。 版权所有(C)2011,JPO&INPIT

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