公开(公告)号：US20050215823A1

公开(公告)日：2005-09-29

申请号：US10811157

申请日：2004-03-29

Applicant: Sudhir Bavikar ,  Asif Maner ,  Ramesh Chidambaram ,  Sudalai Arumugam ,  Sivaram Swaminathan

Inventor： Sudhir Bavikar ,  Asif Maner ,  Ramesh Chidambaram ,  Sudalai Arumugam ,  Sivaram Swaminathan

IPC: C07C209/36 ,  C07C209/50 ,  C07C211/50 ,  C07C211/52 ,  C07C231/12 ,  C07C233/43 ,  C07C237/32 ,  C07C29/36

CPC classification number: C07C211/50 ,  C07C209/36 ,  C07C209/50 ,  C07C231/12 ,  C07C211/52 ,  C07C233/43 ,  C07C237/32

Abstract: This invention relates to a process for the production of 3,3′,4,4′-tetraminobiphenyl (TAB) of formula (1) from non-carcinogenic raw materials, employing Suzuki type biaryl coupling as the key step. sMore particularly, it relates to a three steps process for the production of TAB comprising biaryl aryl coupling of 2-nitro-4-bromoacetanilide (NBA) of formula (2) catalyzed by sulfilimine based palladacycles as catalysts followed by the basic hydrolysis of acetyl group and the reduction of nitro groups with conventional reducing agents.

Abstract translation: 本发明涉及以非致癌原料生产式（1）的3,3'，4,4'-四磺酰联苯（TAB）的方法，采用铃木型联芳基偶联作为关键步骤。 更具体地说，本发明涉及一种制备TAB的三步法，其包括由以亚硫酰亚胺为基础的催化剂催化的式（2）的2-硝基-4-溴乙酰苯胺（NBA）的联芳基偶合，然后乙酰基的碱性水解 和用常规还原剂还原硝基。

公开(公告)号：US06835854B1

公开(公告)日：2004-12-28

申请号：US10804886

申请日：2004-03-19

Applicant: Asif Maner ,  Sudhir Bavikar ,  Arumugam Sudalai ,  Swaminathan Sivaram

Inventor： Asif Maner ,  Sudhir Bavikar ,  Arumugam Sudalai ,  Swaminathan Sivaram

IPC: C07C21100

CPC classification number: C07C209/36 ,  C07C211/55

Abstract: The present invention relates to a process for the preparation of pure high quality 3,3′, 4,4′-tetraminobiphenyl (TAB) in high yields. The present invention also discloses a process for the preparation of 3,3′,4,4′ tetraminobiphenyl (TAB) comprising a three step process: (1) oxidation 3,3′-dichloro 4,4′-diaminobiphenyl (DCB) with 50% aq. H2O2, (2) ammonolysis of the resulting 3,3′-dinitro 4,4′-dinitrobiphenyl (DCDNB) and (3) reduction of 3,3′-diamino-4,4′-dinitrobiphenyl (DADNB) with stannous chloride and concentrated hydrochloric acid.

Abstract translation: 本发明涉及以高产率制备纯高质量3,3'，4,4'-四氨联苯（TAB）的方法。 本发明还公开了一种制备3,3'，4,4'四氨基联苯（TAB）的方法，包括三步法：（1）将3,3'-二氯4,4'-二氨基联苯（DCB）与 50％aq。 H 2 O 2，（2）得到的3,3'-二硝基4,4'-二硝基联苯（DCDNB）的氨解和（3）用氯化亚锡还原3,3'-二氨基-4,4'-二硝基联苯（DADNB） 浓盐酸。

公开(公告)号：US06979749B2

公开(公告)日：2005-12-27

申请号：US10811157

申请日：2004-03-29

Applicant: Sudhir Bavikar ,  Asif Maner ,  Ramesh Kumar Chidambaram ,  Sudalai Arumugam ,  Sivaram Swaminathan

Inventor： Sudhir Bavikar ,  Asif Maner ,  Ramesh Kumar Chidambaram ,  Sudalai Arumugam ,  Sivaram Swaminathan

IPC: C07C209/36 ,  C07C209/50 ,  C07C211/50 ,  C07C211/52 ,  C07C231/12 ,  C07C233/43 ,  C07C237/32 ,  C07C211/00

CPC classification number: C07C211/50 ,  C07C209/36 ,  C07C209/50 ,  C07C231/12 ,  C07C211/52 ,  C07C233/43 ,  C07C237/32

Abstract: This invention relates to a process for the production of 3,3′,4,4′-tetraminobiphenyl (TAB) of formula (1) from non-carcinogenic raw materials, employing Suzuki type biaryl coupling as the key step. More particularly, it relates to a three steps process for the production of TAB comprising biaryl aryl coupling of 2-nitro-4-bromoacetamide (NBA) of formula (2) catalyzed by sulfilimine based palladacycles as catalysts followed by the basic hydrolysis of acetyl group and the reduction of nitro groups with conventional reducing agents.

Abstract translation: 本发明涉及以非致癌原料生产式（1）的3,3'，4,4'-四磺酰联苯（TAB）的方法，采用铃木型联芳基偶联作为关键步骤。 更具体地说，本发明涉及一种制备TAB的三步法，其包括由以亚硫酰亚胺为基础的催化剂催化的式（2）的2-硝基-4-溴乙酰胺（NBA）的联芳基芳基偶联，然后乙酰基的碱性水解 和用常规还原剂还原硝基。