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1.发明申请NOVEL C11 MODIFIED RETROSTEROIDS AS PROGESTERONE RECEPTOR MODULATOR COMPOUNDS 审中-公开新的C11修饰型RETROSTEROIDS作为孕酮受体调节剂化合物
公开(公告)号：WO2008113851A2
公开(公告)日：2008-09-25
申请号：PCT/EP2008/053365
申请日：2008-03-20
Applicant: SOLVAY PHARMACEUTICALS GMBH , MESSINGER, Josef , BOECKER, Christiane , HUSEN, Bettina , THOLE, Heinrich-Hubert , HINAJE, Maria , BUCHHOLZ, Monika
Inventor： MESSINGER, Josef , BOECKER, Christiane , HUSEN, Bettina , THOLE, Heinrich-Hubert , HINAJE, Maria , BUCHHOLZ, Monika
CPC classification number: C07J15/005
Abstract: Described herein arenew retrosteroidal compounds of general formula (I), representing progesterone receptor modulators, and their production, and pharmaceutical preparations containing these compounds. Saidcompounds are preferably used for the treatment of benign gynecological disorders such as endometriosis and uterine fibroids, as well as for female birth control and for HRT.
Abstract translation: 本文描述了新的通式（I）的反甾体化合物，其代表孕酮受体调节剂及其制备，以及含有这些化合物的药物制剂。 所述化合物优选用于治疗良性妇科疾病，如子宫内膜异位和子宫肌瘤，以及女性节育和HRT。
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2.发明申请NOVEL C11 MODIFIED RETROSTEROIDS AS PROGESTERONE RECEPTOR MODULATOR COMPOUNDS 审中-公开新型C11改性复方作为孕激素受体调节剂化合物
公开(公告)号：WO2008113851A3
公开(公告)日：2008-11-20
申请号：PCT/EP2008053365
申请日：2008-03-20
Applicant: SOLVAY PHARM GMBH , MESSINGER JOSEF , BOECKER CHRISTIANE , HUSEN BETTINA , THOLE HEINRICH-HUBERT , HINAJE MARIA , BUCHHOLZ MONIKA
Inventor： MESSINGER JOSEF , BOECKER CHRISTIANE , HUSEN BETTINA , THOLE HEINRICH-HUBERT , HINAJE MARIA , BUCHHOLZ MONIKA
CPC classification number: C07J15/005
Abstract: Described herein arenew retrosteroidal compounds of general formula (I), representing progesterone receptor modulators, and their production, and pharmaceutical preparations containing these compounds. Saidcompounds are preferably used for the treatment of benign gynecological disorders such as endometriosis and uterine fibroids, as well as for female birth control and for HRT.
Abstract translation: 本文描述了代表孕酮受体调节剂及其制备的通式（I）的新型逆甾体化合物和含有这些化合物的药物制剂。 所述化合物优选用于治疗良性妇科疾病，例如子宫内膜异位症和子宫肌瘤，以及用于女性避孕和HRT。
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3.发明申请NOVEL C18 MODIFIED RETROSTEROIDS AS PROGESTERONE RECEPTOR MODULATOR COMPOUNDS 审中-公开新型C18改性复方作为孕激素受体调节剂化合物
公开(公告)号：WO2007039544A1
公开(公告)日：2007-04-12
申请号：PCT/EP2006/066842
申请日：2006-09-28
Applicant: SOLVAY PHARMACEUTICALS GMBH , MESSINGER, Josef , THOLE, Heinrich-Hubert , HUSEN, Bettina , BOECKER, Christiane , HINAJE, Maria , BUCHHOLZ, Monika , MARK, Christoph , KLINGER-DABRAL, Vibhuti
Inventor： MESSINGER, Josef , THOLE, Heinrich-Hubert , HUSEN, Bettina , BOECKER, Christiane , HINAJE, Maria , BUCHHOLZ, Monika , MARK, Christoph , KLINGER-DABRAL, Vibhuti
CPC classification number: C07J15/005
Abstract: Described herein are new retrosteroidal compounds of general formula (I), representing progesterone receptor modulators, and their production, and pharmaceutical preparations containing these compounds. Said compounds are preferably used for the treatment of benign gynecological disorders such as endometriosis and uterine fibroids, as well as for female birth control and for HRT.
Abstract translation: 本文描述了通式（I）的新型逆甾酮化合物，其代表孕酮受体调节剂及其制备，以及含有这些化合物的药物制剂。 所述化合物优选用于治疗良性妇科疾病，例如子宫内膜异位症和子宫肌瘤，以及女性避孕和HRT。
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4.发明申请AMINOALKYL-AMIDOMETHYL-SUBSTITUTED 2- (4-SULPHONYLAMINO) -3-HYDROXY-3 , 4-DIHYDRO-2H-CROMEN-6-YL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL BLOCKERS 审中-公开氨基亚氨基取代的2-（4-磺基苯胺）-3-羟基-3,4-二氢-2H-咔唑-6- L衍生物及其作为钾通道阻断剂的用途
公开(公告)号：WO2006108837A1
公开(公告)日：2006-10-19
申请号：PCT/EP2006/061511
申请日：2006-04-11
Applicant: SOLVAY PHARMACEUTICALS GMBH , MOLONEY, Brian , MARRISON, Lester , ZIEGLER, Dieter , MLINARIC, Michael , BOECKER, Christiane , WESKE, Michael , WITTE, Klaus , FISCHER, Yvan , BRUECKNER, Reinhard
Inventor： MOLONEY, Brian , MARRISON, Lester , ZIEGLER, Dieter , MLINARIC, Michael , BOECKER, Christiane , WESKE, Michael , WITTE, Klaus , FISCHER, Yvan , BRUECKNER, Reinhard
IPC: C07D311/68 , C07D405/12 , C07D413/12 , A61K31/353 , A61K31/497 , A61K31/4025 , A61K31/453 , A61K31/5355 , A61P9/00
CPC classification number: C07D311/68 , C07D405/12 , C07D413/12
Abstract: Cardiovascular active compounds of the general formula (I), wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process are described. Furthermore, pharmaceutical compositions comprising the compounds of Formula (I) are specified.
Abstract translation: 通式（I）的心血管活性化合物，其中R 1，R 2，R 3，R 4， R 5，R 6，R 7，R 8，R 9，R 9， >，R 10和n具有说明书中给出的含义，并且还描述了制备这些化合物的方法和该方法的中间产物。 此外，指定包含式（I）化合物的药物组合物。
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