公开(公告)号：WO0024437A2

公开(公告)日：2000-05-04

申请号：PCT/GB9903558

申请日：1999-10-28

Applicant: ASHBY SCIENT LTD ,  FULLER JESS PAUL ,  PEGG DAVID ,  BIRD ROBERT MCLEAN ,  CLIFFORD TIMOTHY BURGESS ,  CLAYSON TONY

Inventor： FULLER JESS PAUL ,  PEGG DAVID ,  BIRD ROBERT MCLEAN ,  CLIFFORD TIMOTHY BURGESS ,  CLAYSON TONY

IPC: C12M1/00 ,  A61F2/06 ,  A61F2/08 ,  A61F2/10 ,  A61F2/24 ,  A61F2/28 ,  A61F13/00 ,  A61K35/39 ,  A61K45/00 ,  A61K47/04 ,  A61K47/30 ,  A61L15/26 ,  A61L15/44 ,  A61L27/00 ,  A61L27/18 ,  A61L29/06 ,  A61P3/10 ,  A61P5/00 ,  A61P31/00 ,  A61P43/00 ,  C08J9/26 ,  C12M3/00 ,  C12M3/06 ,  C12N5/06

CPC classification number: C08J9/26 ,  A61L15/26 ,  A61L27/18 ,  A61L29/06 ,  C08J2201/0442 ,  C08J2383/04 ,  C12M21/08 ,  C12M23/24 ,  C12M25/02 ,  C08L83/04

Abstract: A method of making a silicone rubber having a structure adapted for growth of cells or living tissue, which comprises contacting a silicone rubber precursor with a biologically-acceptable sacrificial filler, curing the resultant mixture and removing the sacrificial filler to form a structured silicone rubber.

Abstract translation: 一种制造具有适于细胞或活体组织生长的结构的硅橡胶的方法，该方法包括使硅橡胶前体与生物可接受的牺牲填料接触，固化所得混合物并除去牺牲填料以形成结构化硅橡胶。

公开(公告)号：WO0192462A8

公开(公告)日：2002-02-14

申请号：PCT/GB0002073

申请日：2000-05-30

Applicant: ASHBY SCIENT LTD ,  FULLER JESS PAUL ,  CLAYSON TONY ,  BIRD ROBERT MCLEAN ,  CLIFFORD TIMOTHY BURGESS ,  KNIGHTS ANTHONY JAMES

Inventor： FULLER JESS PAUL ,  CLAYSON TONY ,  BIRD ROBERT MCLEAN ,  CLIFFORD TIMOTHY BURGESS ,  KNIGHTS ANTHONY JAMES

IPC: C12M3/00 ,  C12M3/06

CPC classification number: C12M23/34 ,  C12M23/24 ,  C12M25/02 ,  C12M29/10

Abstract: A culture chamber for use in a method of culturing microbiological material, which comprises a wall or at least a portion of a wall consisting of a gas-permeable membrane, a textured interior growth surface arranged for contact with the microbiological material being cultured and at least a portion of the external surface gas-permeable membrane being textured to enhance gas permeability. Preferably, the gas-permeable membrane is textured over the majority of both of its surfaces. This culture chamber provides enhanced gaseous exchange between the interior and exterior of the culture chamber and increased surface area within the culture chamber for cell attachment.

Abstract translation: 一种用于培养微生物材料的方法的培养室，其包括壁或由气体可渗透膜组成的壁的至少一部分，布置成与所培养的微生物材料接触的织构化内部生长表面，并且至少 外表面透气膜的一部分被纹理化以增强透气性。 优选地，透气膜在其两个表面的大部分上是纹理化的。 该培养室在培养室的内部和外部之间提供增强的气体交换，并增加培养室内用于细胞附着的表面积。

公开(公告)号：WO0024437A8

公开(公告)日：2000-06-29

申请号：PCT/GB9903558

申请日：1999-10-28

Applicant: ASHBY SCIENT LTD ,  FULLER JESS PAUL ,  PEGG DAVID ,  BIRD ROBERT MCLEAN ,  CLIFFORD TIMOTHY BURGESS ,  CLAYSON TONY

Inventor： FULLER JESS PAUL ,  PEGG DAVID ,  BIRD ROBERT MCLEAN ,  CLIFFORD TIMOTHY BURGESS ,  CLAYSON TONY

IPC: C12M1/00 ,  A61F2/06 ,  A61F2/08 ,  A61F2/10 ,  A61F2/24 ,  A61F2/28 ,  A61F13/00 ,  A61K35/39 ,  A61K45/00 ,  A61K47/04 ,  A61K47/30 ,  A61L15/26 ,  A61L15/44 ,  A61L27/00 ,  A61L27/18 ,  A61L29/06 ,  A61P3/10 ,  A61P5/00 ,  A61P31/00 ,  A61P43/00 ,  C08J9/26 ,  C12M3/00 ,  C12M3/06 ,  C12N5/06

CPC classification number: C08J9/26 ,  A61L15/26 ,  A61L27/18 ,  A61L29/06 ,  C08J2201/0442 ,  C08J2383/04 ,  C12M21/08 ,  C12M23/24 ,  C12M25/02 ,  C08L83/04

Abstract: A method of making a silicone rubber having a structure adapted for growth of cells or living tissue, which comprises contacting a silicone rubber precursor with a biologically-acceptable sacrificial filler, curing the resultant mixture and removing the sacrificial filler to form a structured silicone rubber.