公开(公告)号：WO2007092115A3

公开(公告)日：2007-12-13

申请号：PCT/US2007000603

申请日：2007-01-10

Applicant: UNIV WAKE FOREST HEALTH SCIENCES ,  HUNDLEY WILLIAM GREGORY ,  HAMILTON CRAIG A ,  LANE KIMBERLY ,  MORGAN TIM ,  TORTI FRANK ,  D AGOSTINO RALPH B

Inventor： HUNDLEY WILLIAM GREGORY ,  HAMILTON CRAIG A ,  LANE KIMBERLY ,  MORGAN TIM ,  TORTI FRANK ,  D AGOSTINO RALPH B

IPC: A61B5/00 ,  A61B5/02

CPC classification number: A61B5/055 ,  A61B6/506 ,  G06K9/6212 ,  G06K2209/05 ,  G06T7/0012 ,  G06T2207/10088 ,  G06T2207/10096 ,  G06T2207/30048

Abstract: Methods, systems and circuits predict cardiotoxicity induced cardiac injury prior to an irreversible state by electronically generating at least one histogram of mean intensities of voxels/pixels in an MRI image of a left ventricle myocardium and electronically determining a likelihood of cardiac injury due to cardiotoxicity based on data from the at least one histogram.

Abstract translation: 方法，系统和电路通过电子地生成左心室心肌的MRI图像中的至少一个体素/像素的平均强度的直方图来预测在不可逆状态之前引起的心脏损伤的心脏毒性，并且电子地确定由于心脏毒性引起的心脏损伤的可能性 来自至少一个直方图的数据。

公开(公告)号：WO2007092159A3

公开(公告)日：2008-03-20

申请号：PCT/US2007001927

申请日：2007-01-25

Applicant: UNIV WAKE FOREST HEALTH SCIENCES ,  HUNDLEY WILLIAM GREGORY ,  HAMILTON CRAIG A ,  D AGOSTINO RALPH B

Inventor： HUNDLEY WILLIAM GREGORY ,  HAMILTON CRAIG A ,  D AGOSTINO RALPH B

IPC: G06T7/00 ,  G06T5/00

CPC classification number: G06T7/0012 ,  A61B5/0044 ,  A61B5/055 ,  A61B5/7285 ,  A61B6/466 ,  A61B6/503 ,  A61B6/504 ,  A61B6/506 ,  A61B6/541 ,  G01R33/283 ,  G01R33/546 ,  G06T2207/10088 ,  G06T2207/20104 ,  G06T2207/30048 ,  Y10S128/92 ,  Y10S128/921 ,  Y10S128/922 ,  Y10S128/923 ,  Y10S128/924

Abstract: Physician interactive workstations with global cardiac voxel distribution visualization may also include one or more of a 3-D color scale image of a population of voxel in the heart and/or an electronic boundary-tracing tool configured to accept user input to electronically define at least one boundary of a target region of a heart in a medical image of a patient on a display. The workstation may be configured to evaluate intensity of voxels associated with tissue within the defined boundary of the target region of the heart whereby cardiotoxicity is evaluated.

Abstract translation: 具有全球心脏体素分布可视化的医师交互式工作站还可以包括心脏中的体素群体的3-D色标图像中的一个或多个，和/或配置成接受用户输入至少以电子方式定义的电子边界跟踪工具 在显示器上患者的医学图像中的心脏的目标区域的一个边界。 工作站可以被配置为评估与心脏的目标区域的限定边界内的组织相关联的体素的强度，其中评估心脏毒性。