公开(公告)号：WO2008015720A2

公开(公告)日：2008-02-07

申请号：PCT/IT2007000551

申请日：2007-07-31

Applicant: IDI IRCCS ,  CONSIGLIO NAZIONALE RICERCHE ,  UNIV ROMA ,  D ATRI STEFANIA ,  FAILLA CRISTINA MARIA ,  LACAL PEDRO MIGUEL ,  ORECCHIA ANGELA ,  ZAMBRUNO GIOVANNA ,  TRAMONTANO ANNA ,  SORO SIMONETTA ,  MOREA VERONICA

Inventor： D ATRI STEFANIA ,  FAILLA CRISTINA MARIA ,  LACAL PEDRO MIGUEL ,  ORECCHIA ANGELA ,  ZAMBRUNO GIOVANNA ,  TRAMONTANO ANNA ,  SORO SIMONETTA ,  MOREA VERONICA

IPC: C07K14/71 ,  A61K38/18

CPC classification number: C07K14/71

Abstract: Description of a sequence peptide isolated in the domain II type-immunoglobulin (Type-Ig) of the Vascular Endothelial Growth Factor receptor 1 (VEGF-1) binding integrin a5ß1, usable for the preparation of pharmacological agents having proangiogenic activity.

Abstract translation: 描述分离在血管内皮生长因子受体1（VEGF-1）结合整联蛋白a5β1的结构域II型免疫球蛋白（Type-Ig）中的序列肽，可用于制备具有促血管生成活性的药理学试剂。