公开(公告)号：WO2012177756A3

公开(公告)日：2013-05-10

申请号：PCT/US2012043342

申请日：2012-06-20

Applicant: BASF SE ,  SONG ZHIQIANG ,  DEISENROTH TED

Inventor： SONG ZHIQIANG ,  DEISENROTH TED

IPC: A61K31/16 ,  A61K9/70 ,  A61K31/13 ,  A61P17/02 ,  A61P31/04

CPC classification number: A61F13/00034 ,  A61F2013/00314

Abstract: The present application discloses preparations of antimicrobial wound dressings. Strongly binding polymeric dialkyi aminoalkyi (meth)acrylates are used to treat highly absorbent wound dressing materials. The resulting finish is highly antimicrobial effective and non- leachable.

Abstract translation: 本申请公开了抗微生物伤口敷料的制剂。 使用强力结合聚合物二烷基氨基烷基（甲基）丙烯酸酯来处理高吸收性伤口敷料材料。 最终的结果是高度抗微生物有效和不可浸出。

公开(公告)号：WO2011130101A3

公开(公告)日：2012-03-01

申请号：PCT/US2011031658

申请日：2011-04-08

Applicant: BASF SE ,  CUNKLE GLEN T ,  HENDRICKS-GUY CARMEN ,  DEISENROTH TED

Inventor： CUNKLE GLEN T ,  HENDRICKS-GUY CARMEN ,  DEISENROTH TED

IPC: D06M11/64 ,  D06M13/217 ,  D06M15/13 ,  D06M15/347

CPC classification number: A01N33/12 ,  D06M13/463 ,  D06M15/03 ,  D06M15/09 ,  D06M15/11 ,  D06M15/13 ,  D06M15/227 ,  D06M15/263 ,  D06M15/285 ,  D06M16/00 ,  A01N25/34 ,  A01N2300/00

Abstract: Highly active, leach-resistant, antimicrobial nonwoven textiles are prepared by treating at least one surface of the nonwoven material with an anionic polyelectrolyte, such as carboxymethyl cellulose, alginic acid, poly(acrylic acid) etc and at least one select quaternary ammonium antimicrobial agent. The textiles of the invention, and products produced from them, exhibit a highly effective quick kill rate, for example a log 4 CFU reduction within a 5 minute contact time, against microbes such as fungi and gram (-) and gram (+) bacteria.

Abstract translation: 通过用阴离子聚电解质（例如羧甲基纤维素，藻酸，聚（丙烯酸）等）和至少一种选择的季铵抗微生物剂处理非织造材料的至少一个表面来制备高活性，耐浸出，抗微生物的非织造织物 。 本发明的纺织品以及由它们生产的产品具有非常有效的快速杀死率，例如在5分钟接触时间内对抗微生物如真菌和克（ - ）和克（+）细菌的log 4 CFU 。

公开(公告)号：WO2022108772A1

公开(公告)日：2022-05-27

申请号：PCT/US2021/058313

申请日：2021-11-05

Applicant: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO ,  BASF SE ,  DEISENROTH, Ted, W.

Inventor： KUMACHEV, Eugenia ,  ANDRE, Valerie ,  CHEN, Zhengkun

IPC: B01J13/20 ,  B01J13/08 ,  B01J13/10 ,  B01J13/22

Abstract: Disclosed are embodiments of a multicellular spheroid, including a core containing first skin cells; the core can have an average diameter of about 10 μm to about 900 μm. The multicellular spheroid may further include a shell overlaying the core, the shell having second skin cells. Further disclosed are systems containing such multicellular spheroids and methods of preparation and use of multicellular spheroids.

公开(公告)号：WO2011130101A2

公开(公告)日：2011-10-20

申请号：PCT/US2011/031658

申请日：2011-04-08

Applicant: BASF SE ,  CUNKLE, Glen, T. ,  HENDRICKS-GUY, Carmen ,  DEISENROTH, Ted

Inventor： CUNKLE, Glen, T. ,  HENDRICKS-GUY, Carmen ,  DEISENROTH, Ted

IPC: D06M11/64 ,  D06M13/217 ,  D06M15/13 ,  D06M15/347

CPC classification number: A01N33/12 ,  D06M13/463 ,  D06M15/03 ,  D06M15/09 ,  D06M15/11 ,  D06M15/13 ,  D06M15/227 ,  D06M15/263 ,  D06M15/285 ,  D06M16/00 ,  A01N25/34 ,  A01N2300/00

Abstract: Highly active, leach-resistant, antimicrobial nonwoven textiles are prepared by treating at least one surface of the nonwoven material with an anionic polyelectrolyte, such as carboxymethyl cellulose, alginic acid, poly(acrylic acid) etc and at least one select quaternary ammonium antimicrobial agent. The textiles of the invention, and products produced from them, exhibit a highly effective quick kill rate, for example a log 4 CFU reduction within a 5 minute contact time, against microbes such as fungi and gram (-) and gram (+) bacteria.

Abstract translation: 通过用阴离子聚电解质（例如羧甲基纤维素，藻酸，聚（丙烯酸）等）和至少一种选择的季铵抗微生物剂处理非织造材料的至少一个表面来制备高活性，耐浸出，抗微生物的非织造织物 。 本发明的纺织品以及由它们生产的产品具有非常有效的快速杀死率，例如在5分钟接触时间内对抗微生物如真菌和克（ - ）和克（+）细菌的log 4 CFU 。

公开(公告)号：WO2007085552A2

公开(公告)日：2007-08-02

申请号：PCT/EP2007050420

申请日：2007-01-17

Applicant: CIBA SC HOLDING AG ,  HUANG XINYU ,  DEISENROTH TED ,  PREUSS ANDREA ,  MARQUAIS-BIENEWALD SOPHIE ,  JENNINGS JOHN ,  HENDRICKS-GUY CARMEN

Inventor： HUANG XINYU ,  DEISENROTH TED ,  PREUSS ANDREA ,  MARQUAIS-BIENEWALD SOPHIE ,  JENNINGS JOHN ,  HENDRICKS-GUY CARMEN

CPC classification number: C08G73/0206 ,  A01N33/04 ,  A01N33/08 ,  A01N33/12 ,  A01N37/12 ,  A01N37/40 ,  A01N41/04 ,  A01N43/50 ,  A01N43/54 ,  A01N55/00 ,  A61K8/84 ,  A61K31/787 ,  A61K2800/92 ,  A61Q5/02 ,  A61Q15/00 ,  A61Q17/005 ,  C08L79/02 ,  C11D3/3723 ,  C11D3/48

Abstract: Polymeric anti-microbial agents produced by substituting the nitrogen atoms in the backbone of ethenimine polymers are provided. The agents are believed to have low human toxicity while being effective against a variety of pathogens and are useful in applications involving human contact, such as cosmetics, hair care products and textiles, as well as in applications with much less human contact, such as coatings.

Abstract translation: 提供通过替代乙烯亚胺聚合物的主链中的氮原子制备的聚合抗微生物剂。 据信这些试剂具有低的人体毒性，同时对各种病原体有效，并且可用于涉及人体接触的应用，例如化妆品，护发产品和纺织品，以及在人接触少得多的应用中，例如涂层 。

公开(公告)号：WO2006015963A1

公开(公告)日：2006-02-16

申请号：PCT/EP2005/053789

申请日：2005-08-03

Applicant: CIBA SPECIALTY CHEMICALS HOLDING INC. ,  CUESTA, Fabienne ,  DEISENROTH, Ted ,  FONDEKAR, Kamalesh Pai ,  JOSHI, Ramachandra V. ,  ROHRINGER, Peter ,  SHADAKSHARI, Uma ,  ZELGER, Josef

Inventor： CUESTA, Fabienne ,  DEISENROTH, Ted ,  FONDEKAR, Kamalesh Pai ,  JOSHI, Ramachandra V. ,  ROHRINGER, Peter ,  SHADAKSHARI, Uma ,  ZELGER, Josef

IPC: D21H21/30

CPC classification number: C09B67/0063 ,  C09B67/0033 ,  C09B67/009 ,  D21H19/42 ,  D21H21/30

Abstract: The invention relates to a fluorescent pigment comprising a) a melamine-formaldehyde polycondensation product, b) a distyryl biphenyl fluorescent whitening agent (FWA) of the formula (1), in which R 1 represents hydrogen, chlorine or C 1 -C 4 alkoxy and M represents hydrogen, an alkaline or alkaline earth metal, ammonium or ammonium that is mono-, di-, tri- or tetrasubstituted by C 1 -C 4 alkyl or C 2 -C 4 hydroxyalkyl and, optionally, c) at least one additional fluorescent whitening agent, a process for its preparation and use thereof for the fluorescent whitening of paper, especially in coating.

Abstract translation: 本发明涉及一种荧光颜料，其包含a）三聚氰胺 - 甲醛缩聚产物，b）式（1）的二苯乙烯基联苯荧光增白剂（FWA），其中R

公开(公告)号：WO2015157261A1

公开(公告)日：2015-10-15

申请号：PCT/US2015/024681

申请日：2015-04-07

Applicant: BASF SE ,  DEISENROTH, Ted ,  CUNKLE, Glen, Thomas ,  JUNKER, Lauren ,  KUEPFERT, Michael ,  ODORISIO, Paul ,  SAUNDERS, Steven, N. ,  RAMNARINE, Vishal ,  ABRAHAM, Neethu

Inventor： DEISENROTH, Ted ,  CUNKLE, Glen, Thomas ,  JUNKER, Lauren ,  KUEPFERT, Michael ,  ODORISIO, Paul ,  SAUNDERS, Steven, N. ,  RAMNARINE, Vishal ,  ABRAHAM, Neethu

IPC: A61K8/72 ,  A61K8/362 ,  A61K8/44 ,  A61Q11/00

CPC classification number: A61K8/88 ,  A61K8/0204 ,  A61K8/21 ,  A61K8/27 ,  A61K8/463 ,  A61K8/4926 ,  A61K8/731 ,  A61K8/733 ,  A61K8/85 ,  A61K2800/594 ,  A61Q11/00 ,  C08B3/12 ,  C08G63/12 ,  C08G63/668 ,  C08G63/685 ,  C08G69/44

Abstract: The application relates to oral care compositions comprising substantive polyesteramides formed from polyols, polycarboxylic acids (or esters, anhydrides or halides thereof) and arginine. The formed polyesteramides are active in biofilm inhibition, biofilm dissolution and retarding or preventing acid production from oral bacteria.

Abstract translation: 本申请涉及包含由多元醇，多元羧酸（或其酯，酸酐或其卤化物）和精氨酸形成的实质性聚酯酰胺的口腔护理组合物。 形成的聚酯酰胺在生物膜抑制，生物膜溶解和阻滞或防止口腔细菌产生酸中具有活性。

公开(公告)号：WO2012177731A2

公开(公告)日：2012-12-27

申请号：PCT/US2012/043300

申请日：2012-06-20

Applicant: BASF SE ,  SONG, Zhiqiang ,  DEISENROTH, Ted

Inventor： SONG, Zhiqiang ,  DEISENROTH, Ted

CPC classification number: C08F220/34 ,  A01N37/12 ,  C08F220/60 ,  C08L75/04 ,  C09D5/14 ,  C09D7/63

Abstract: The present application relates to oligomeric antimicrobial compounds and compositions comprising the same. The oligomers are formed by polymerizing aminoalkyi (meth)acrylate or aminoalkyi (meth)acrylamide monomer(s). In addition to imparting materials with broad spectrum antimicrobial activity, the oligomers can impart antimicrobial activity to substrates such as hair and skin.

Abstract translation: 本申请涉及低聚抗微生物化合物和包含其的组合物。 通过聚合（甲基）丙烯酸氨基烷基酯或氨基烷基（甲基）丙烯酰胺单体形成低聚物。 除了赋予具有广谱抗菌活性的材料之外，低聚物可以赋予基底如头发和皮肤的抗微生物活性。

公开(公告)号：WO2008132045A2

公开(公告)日：2008-11-06

申请号：PCT/EP2008054519

申请日：2008-04-15

Applicant: CIBA HOLDING INC ,  DEISENROTH TED ,  HENDRICKS-GUY CARMEN ,  MUEHLEBACH ANDREAS ,  PREUSS ANDREA ,  HOELZL WERNER ,  HUANG XINYU

Inventor： DEISENROTH TED ,  HENDRICKS-GUY CARMEN ,  MUEHLEBACH ANDREAS ,  PREUSS ANDREA ,  HOELZL WERNER ,  HUANG XINYU

IPC: A01N33/12 ,  A01N25/10 ,  A01P1/00

CPC classification number: A01N37/12 ,  A01N25/10 ,  A01N25/34 ,  A01N33/12 ,  A61L15/46 ,  A61L27/34 ,  A61L27/54 ,  A61L29/085 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/208 ,  A61L2300/404 ,  A61L2300/606 ,  C09D4/00 ,  A01N37/44 ,  C08F220/34

Abstract: The present invention provides a process for coating the surface of a substrate comprises the following steps (i) oxidizing the surface of the substrate (ii) applying a composition comprising one or more quaternary ammonium compounds carrying one or more ethylenically unsaturated groups onto the oxidized surface of the substrate and (iii) curing the composition in order to form a coating layer, and substrates obtainable by the latter process.

Abstract translation: 本发明提供一种涂覆基材表面的方法，包括以下步骤（i）氧化基材表面（ii）将包含一种或多种带有一个或多个烯键式不饱和基团的季铵化合物的组合物施加到氧化表面上 和（iii）固化组合物以形成涂层，以及通过后一工艺可获得的底物。

公开(公告)号：WO2005028749A1

公开(公告)日：2005-03-31

申请号：PCT/EP2004/052119

申请日：2004-09-10

Applicant: CIBA SPECIALTY CHEMICALS HOLDING INC. ,  TRABER, Rainer Hans ,  DEISENROTH, Ted ,  GALLE, Sandra ,  DBALY, Helena

Inventor： TRABER, Rainer Hans ,  DEISENROTH, Ted ,  GALLE, Sandra ,  DBALY, Helena

IPC: D21H21/30

CPC classification number: D06M13/358 ,  C11D3/0063 ,  C11D3/42 ,  D21H21/30

Abstract: Compositions comprising (A) a total of from 2 to 30 % by weight, based on the total composition (A) + (B), of one or more amino alcohols of formula (1) herein R 1 , R 2 , R 3 and R 4 are each independently of the others hydrogen, C 1 -C 12 alkyl, C5 -C 24 aryl or C 6 -C 36 aralkyl, and R 5 and R 6 are each independently of the other hydrogen or C 1 -C 4 alkyl; and (B) from 70 to 98 % by weight, based on the total composition (A) + (B), of a fluorescent whitening agent of formula (2) herein X is hydrogen, an alkali metal ion, an ammonium ion or a hydroxyalkylammonium radical derived from the amino alcohol of formula (1), and R 7 , R 8 , R 9 and R 10 are each independently of the others -OR 11 , -NR 11 R 12 or a group of formula (3) wherein R 11 , and R 12 are each independently of the other hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl, carboxyalkyl, dicarboxyalkyl, H 2 N-CO-alkyI or alkylthio, are distinguished by high solubility in water and by high storage stability of the aqueous solutions.

Abstract translation: 基于总组合物（A）+（B）），本文中R1，R2，R3和R4的一种或多种式（1）氨基醇的总重量为2至30重量％的组合物各自 独立于其它氢，C 1 -C 12烷基，C 5 -C 24芳基或C 6 -C 36芳烷基，R 5和R 6各自独立地为氢或C 1 -C 4烷基; 和（B）70至98重量％，基于本发明式（2）的荧光增白剂的总组合物（A）+（B），X为氢，碱金属离子，铵离子或 衍生自式（1）的氨基醇的羟烷基铵基和R7，R8，R9和R10各自独立地为-OR11，-NR11R12或式（3）的基团，其中R11和R12各自独立地为 其他氢，烷基，羟烷基，烷氧基烷基，羧基烷基，二羧基烷基，H 2 N -CO-烷基或烷硫基，其特征在于在水中的高溶解度和水溶液的高储存稳定性。