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    POROUS AND NON-POROUS CELL CULTURE SUBSTRATE
    1.
    发明申请
    POROUS AND NON-POROUS CELL CULTURE SUBSTRATE 审中-公开
    多孔和非多孔细胞培养基质

    公开(公告)号：WO2012027651A1

    公开(公告)日：2012-03-01

    申请号：PCT/US2011/049306

    申请日：2011-08-26

    Applicant: CORNING INCORPORATED ,  DEROSA, Michael, E ,  LAHIRI, Joydeep ,  RAO, Hongwei, H ,  YUEN, Po Ki

    Inventor： DEROSA, Michael, E ,  LAHIRI, Joydeep ,  RAO, Hongwei, H ,  YUEN, Po Ki

    IPC: C08J7/02 ,  C12N5/00

    CPC classification number: C08J7/02 ,  C08J2323/08 ,  C08J2325/06 ,  C12M23/22 ,  C12M25/14

    Abstract: A cell culture article has substrate that is predominantly opaque and that provides a three-dimensional (e.g., irregular) surface, but incorporates an optically transparent, substantially regular (e.g., two-dimensional) surface to serve as a microscopic observation and imaging window for the 3D cell culture. In many embodiments, the 3D portion of the substrate occupies greater than 99% of the surface while the 2D portion occupies less than 1% of the surface so as not to substantially disrupt the general 3D culture environment.

    Abstract translation: 细胞培养物具有主要是不透明的并且提供三维（例如，不规则）表面的基底，但是包含光学透明的，基本上规则的（例如，二维）表面，用作微观观察和成像窗口 3D细胞培养。 在许多实施例中，基板的3D部分占据表面的大于99％，而2D部分占据表面的1％以下，以免基本上破坏一般的3D文化环境。

    METHOD OF PREVENTING OPTICAL FIBER FAILURE IN HIGH POWER APPLICATION
    5.
    发明申请
    METHOD OF PREVENTING OPTICAL FIBER FAILURE IN HIGH POWER APPLICATION 审中-公开
    防止高功率应用中光纤故障的方法

    公开(公告)号：WO2006073991A1

    公开(公告)日：2006-07-13

    申请号：PCT/US2005/047236

    申请日：2005-12-28

    Applicant: CORNING INCORPORATED ,  LOGUNOV, Stephan L ,  WINNINGHAM, Michael J ,  DEMARTINO, Steven E ,  DEROSA, Michael E ,  GLAESEMANN, Gregory S ,  NEUKIRCH, Ulrich

    Inventor： LOGUNOV, Stephan L ,  WINNINGHAM, Michael J ,  DEMARTINO, Steven E ,  DEROSA, Michael E ,  GLAESEMANN, Gregory S ,  NEUKIRCH, Ulrich

    IPC: C03C25/10

    CPC classification number: C03C25/106 ,  C03C25/1065 ,  G02B6/02395 ,  G02B6/03633 ,  G02B6/03694

    Abstract: A method of minimizing localized heating of, or minimizing signal losses across a source of loss in, an optical fiber used in transmission of a high power optical signal at an operating wavelength. These methods include the steps of: providing an optical fiber which comprises a coating characterized by either (i) an absorbance of less than about 4.5 dB/cm at the operating wavelength or (ii) a refractive index lower than the refractive index of a cladding layer of the optical fiber by more than about 3x10-3 at the operating wavelength, or (iii) both (i) and (ii); and transmitting a optical signal having a power greater than about 250 mW through the optical fiber, wherein the coating, cladding layer, or combination thereof are selected to minimize localized heating of the optical fiber or to result in a signal loss across a source of loss that is less than about 250 mW at the operating wavelength.

    Abstract translation: 一种使在工作波长的高功率光信号传输中使用的光纤中的损耗源的局部加热的局部加热或减少信号损失最小化的方法。 这些方法包括以下步骤：提供光纤，其包括涂层，其特征在于：（i）在工作波长处的吸光度小于约4.5dB / cm，或（ii）低于包层的折射率的折射率 （iii）（i）和（ii）两者之间的光纤层超过约3×10 -3; 并且通过光纤传输具有大于约250mW的功率的光信号，其中选择涂层，包层或其组合以使光纤的局部加热最小化或导致跨越损耗源的信号损失 在工作波长处小于约250mW。

    MICROPOROUS THERMOPLASTIC SHEETS
    6.
    发明申请
    MICROPOROUS THERMOPLASTIC SHEETS 审中-公开

    公开(公告)号：WO2012027687A8

    公开(公告)日：2012-03-01

    申请号：PCT/US2011/049379

    申请日：2011-08-26

    Applicant: CORNING INCORPORATED ,  DEROSA, Michael E ,  UPTON, Todd M ,  ZHANG, Ying

    Inventor： DEROSA, Michael E ,  UPTON, Todd M ,  ZHANG, Ying

    IPC: C08J7/02 ,  C12N5/00

    Abstract: Thermoplastic polymeric sheets are rendered microporous and remain substantially flat by contacting the sheet with a first fluid composition that contains or more solvents for the polymeric sheet to render the sheet microporous and then contacting the microporous sheet with a second fluid composition that is substantially free of solvents for the polymer and that contains a non-solvent that is miscible with the one or more solvents of the first composition. Contacting the microporous sheet with the second fluid composition preferably occurs prior to substantial evaporation of the first fluid compositions, or solvents thereof, from the microporous sheet.

    RETICULATED PORE FORMERS FOR CERAMIC ARTICLES
    8.
    发明申请
    RETICULATED PORE FORMERS FOR CERAMIC ARTICLES 审中-公开
    陶瓷制品的制造商

    公开(公告)号：WO2008013717A1

    公开(公告)日：2008-01-31

    申请号：PCT/US2007/016293

    申请日：2007-07-18

    Applicant: CORNING INCORPORATED ,  DEROSA, Michael E ,  WIGHT, John F Jr.

    Inventor： DEROSA, Michael E ,  WIGHT, John F Jr.

    IPC: C04B35/185 ,  C04B35/195 ,  C04B35/478 ,  C04B35/565 ,  C04B35/584 ,  C04B38/06 ,  C04B38/10 ,  C08J9/36

    CPC classification number: C04B35/195 ,  C04B35/62655 ,  C04B38/0615 ,  C04B2111/00793 ,  C04B2111/0081 ,  C04B2235/3217 ,  C04B2235/3418 ,  C04B2235/3445 ,  C04B2235/349 ,  C04B2235/6562 ,  C04B2235/6565 ,  C04B35/00 ,  C04B38/0006

    Abstract: The present invention relates to reticulated pore formers and ceramic articles including reticulated pore structures. The pore former of the present invention provides open pores having an interconnected generally three-dimensional structure and are useful in the manufacture of porous ceramic articles, such as honeycomb diesel particulate filters and catalyzed filters. The reticulated pore formers of the present invention provide controlled pore size and reticulated channel morphology in the finished ceramic articles. The pore size and the length of the pore channel may be controlled by using the desired foam structure and size. The pore formers may be mixed into a ceramic batch and extruded through a forming die resulting in a ceramic article that has semi-continuous reticulated channels throughout the entire body after firing to remove the pore former. The pore formers of the present invention are flexible and highly elastic, which inhibits rupture of the particle during the extrusion process. The use of reticulated pore formers enables the manufacture of highly permeable ceramic filters with controlled pore size distribution.

    Abstract translation: 本发明涉及网状孔隙形成剂和包括网状孔结构的陶瓷制品。 本发明的成孔剂提供具有互连的通常三维结构的开孔，并且可用于制造多孔陶瓷制品，例如蜂窝状柴油颗粒过滤器和催化过滤器。 本发明的网状成孔剂在成品陶瓷制品中提供受控的孔径和网状通道形态。 可以通过使用所需的泡沫结构和尺寸来控制孔径和孔道的长度。 成孔剂可以混合成陶瓷批料并通过成形模挤出，得到陶瓷制品，其在烧制后在全身上具有半连续网状通道以除去成孔剂。 本发明的成孔剂是柔性的和高弹性的，其抑制了挤出过程中颗粒的破裂。 网状成孔剂的使用使得能够制造具有可控孔径分布的高渗透性陶瓷过滤器。

    MICROPOROUS THERMOPLASTIC SHEETS
    9.
    发明申请
    MICROPOROUS THERMOPLASTIC SHEETS 审中-公开
    微波热塑片

    公开(公告)号：WO2012027687A1

    公开(公告)日：2012-03-01

    申请号：PCT/US2011049379

    申请日：2011-08-26

    Applicant: 4CORNING INC 1 ,  DEROSA MICHAEL E ,  UPTON TODD M ,  ZHANG YING

    Inventor： DEROSA MICHAEL E ,  UPTON TODD M ,  ZHANG YING

    IPC: C08J7/02 ,  C12N5/00

    CPC classification number: C08J7/02 ,  C08J2325/06 ,  C08J2365/00

    Abstract: Thermoplastic polymeric sheets are rendered microporous and remain substantially flat by contacting the sheet with a first fluid composition that contains or more solvents for the polymeric sheet to render the sheet microporous and then contacting the microporous sheet with a second fluid composition that is substantially free of solvents for the polymer and that contains a non-solvent that is miscible with the one or more solvents of the first composition. Contacting the microporous sheet with the second fluid composition preferably occurs prior to substantial evaporation of the first fluid compositions, or solvents thereof, from the microporous sheet.

    Abstract translation: 将热塑性聚合物片材变成微孔并且通过使片材与含有或多于聚合物片材的溶剂的第一流体组合物接触而保持基本上平坦，以使片材微孔，然后使微孔片材与基本上不含溶剂的第二流体组合物接触 并且含有与第一组合物的一种或多种溶剂混溶的非溶剂。 在微孔片与第二流体组合物接触之前，优选在第一种流体组合物或其溶剂从微孔片大量蒸发之前进行。

    MICROPOROUS CELL CULTURE SUBSTRATES
    10.
    发明申请
    MICROPOROUS CELL CULTURE SUBSTRATES 审中-公开
    微生物细胞培养基质

    公开(公告)号：WO2012027653A1

    公开(公告)日：2012-03-01

    申请号：PCT/US2011/049310

    申请日：2011-08-26

    Applicant: CORNING INCORPORATED ,  DEROSA, Michael, E ,  RAO, Hongwei, H

    Inventor： DEROSA, Michael, E ,  RAO, Hongwei, H

    IPC: C08J7/02 ,  C12M1/34

    CPC classification number: C08J7/02 ,  C08J2325/06 ,  C08J2365/00

    Abstract: Surfaces of thermoplastic articles are rendered microporous by contacting the surface with a composition that includes a solvent. The article has a birefringence of 0.0001 or greater and the composition has a solvent strength configured to swell but not dissolve the polymer.

    Abstract translation: 通过使表面与包含溶剂的组合物接触，使热塑性制品的表面变成微孔。 该制品具有0.0001以上的双折射性，并且该组合物具有溶胀强度但不溶解聚合物的溶剂强度。

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