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    PREMOUNTED FLUID CONVEYANCE ASSEMBLY FOR CELL EXPANSION SYSTEM AND METHOD OF USE ASSOCIATED THEREWITH
    4.
    发明申请
    PREMOUNTED FLUID CONVEYANCE ASSEMBLY FOR CELL EXPANSION SYSTEM AND METHOD OF USE ASSOCIATED THEREWITH 审中-公开
    用于细胞扩增系统的预制流体输送装置及其使用方法

    公开(公告)号：WO2010062599A1

    公开(公告)日：2010-06-03

    申请号：PCT/US2009/062213

    申请日：2009-10-27

    Applicant: CARIDIANBCT, INC. ,  DODD, Jon, A. ,  DILORENZO, Thomas, G. ,  CORBIN, Frank, III ,  ANTWILER, Glen, Delbert

    Inventor： DODD, Jon, A. ,  DILORENZO, Thomas, G. ,  CORBIN, Frank, III ,  ANTWILER, Glen, Delbert

    IPC: C12M1/12 ,  C12M3/06

    CPC classification number: C12M23/48 ,  C12M23/42 ,  C12M25/10 ,  C12M25/12 ,  C12M29/00

    Abstract: A premounted fluid conveyance assembly for use with a cell expansion machine comprises a tubing-organizer and a fluid conveyance system. The fluid conveyance system is at least partially attached to the tubing-organizer, and the fluid conveyance system comprises an oxygenator or gas transfer module, a length of tubing and a bioreactor all fluidly interconnected. The premounted fluid conveyance assembly is adapted to be detachably-attached to the cell expansion machine. Accordingly, after a premounted fluid conveyance assembly is used, it is removed from the cell expansion machine by disengaging it from the cell expansion machine. Thereafter, another premounted fluid conveyance assembly can be attached in place of the previously used premounted fluid conveyance assembly.

    Abstract translation: 用于细胞膨胀机的预先安装的流体输送组件包括管组织器和流体输送系统。 流体输送系统至少部分地附接到管道 - 组织器，并且流体输送系统包括充气器或气体传递模块，一段管道和生物反应器全部流体互连。 预先安装的流体输送组件适于可拆卸地附接到细胞膨胀机。 因此，在使用预先安装的流体输送组件之后，通过使其从电池膨胀机脱离而从电池膨胀机移除。 此后，可以安装另一个预先安装的流体输送组件来代替先前使用的预先安装的流体输送组件。

    CONFIGURABLE METHODS AND SYSTEMS OF GROWING AND HARVESTING CELLS IN A HOLLOW FIBER BIOREACTOR SYSTEM
    5.
    发明申请
    CONFIGURABLE METHODS AND SYSTEMS OF GROWING AND HARVESTING CELLS IN A HOLLOW FIBER BIOREACTOR SYSTEM 审中-公开
    在空心纤维生物反应器系统中生长和收获细胞的可配置方法和系统

    公开(公告)号：WO2012048275A2

    公开(公告)日：2012-04-12

    申请号：PCT/US2011055451

    申请日：2011-10-07

    Applicant: CARIDIANBCT INC ,  STANTON EDWARD ALLAN IV ,  ANTWILER GLEN DELBERT ,  HOWLEY PATRICK J ,  KINZIE MICHAEL E ,  DODD JON A ,  MEDINA CASEY V

    Inventor： STANTON EDWARD ALLAN IV ,  ANTWILER GLEN DELBERT ,  HOWLEY PATRICK J ,  KINZIE MICHAEL E ,  DODD JON A ,  MEDINA CASEY V

    IPC: C12N5/00

    CPC classification number: C12M41/44 ,  C12M23/42 ,  C12M23/44 ,  C12M25/10 ,  C12M25/12 ,  C12M29/16 ,  C12M29/20 ,  C12M41/48 ,  G06F8/38

    Abstract: Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.

    Abstract translation: 这里描述的实施例一般涉及用于配置包括生物反应器的细胞扩增系统的设置的方法和系统。 通过用户界面，用户可以配置显示设置，系统设置和与用于加载，生长和/或收集细胞的协议相关的设置。 在配置协议和关联进程的设置时，在实施例中显示单元扩展系统的图表视图或窗口。 图表视图将过程设置显示为图形用户界面元素。 可用于配置的设置在图表视图中启用以供选择。 图表视图允许用户可视化可用于任务配置的设置并配置启用的设置。 配置的设置被存储并且能够被检索用于后续执行或修改适用的协议。

    CUSTOMIZABLE METHODS AND SYSTEMS OF GROWING AND HARVESTING CELLS IN A HOLLOW FIBER BIOREACTOR SYSTEM
    6.
    发明申请
    CUSTOMIZABLE METHODS AND SYSTEMS OF GROWING AND HARVESTING CELLS IN A HOLLOW FIBER BIOREACTOR SYSTEM 审中-公开
    在空心纤维生物反应器系统中生长和收获细胞的可定制方法和系统

    公开(公告)号：WO2012048276A3

    公开(公告)日：2012-08-02

    申请号：PCT/US2011055453

    申请日：2011-10-07

    Applicant: TERUMO BCT INC ,  STANTON EDWARD ALLAN IV ,  ANTWILER GLEN DELBERT ,  HOWLEY PATRICK J ,  KINZIE MICHAEL E ,  DODD JON A ,  MEDINA CASEY V

    Inventor： STANTON EDWARD ALLAN IV ,  ANTWILER GLEN DELBERT ,  HOWLEY PATRICK J ,  KINZIE MICHAEL E ,  DODD JON A ,  MEDINA CASEY V

    IPC: G05B19/042 ,  C12M3/06

    CPC classification number: C12M41/44 ,  C12M23/42 ,  C12M23/44 ,  C12M25/10 ,  C12M25/12 ,  C12M29/16 ,  C12M29/20 ,  C12M41/48 ,  G06F8/38

    Abstract: Embodiments described herein generally relate to methods and systems for customizing protocols for use with a cell expansion system. Through a user interface, a user may create a custom task for loading, growing and/or harvesting cells. A custom task may comprise one or more steps, in which a user may add or omit steps, as desired. Data may be entered for settings associated with a custom task, in which embodiments provide for such data to be entered each time the custom task is performed. In another embodiment, the settings for a custom task may be configured, in which such settings may be stored and retrieved upon selection of the custom task. Customization and configuration of a custom task may occur using a diagram view of the cell expansion system, in which process settings are associated with graphical user interface elements.

    Abstract translation: 这里描述的实施例总体上涉及用于定制用于单元扩展系统的协议的方法和系统。 通过用户界面，用户可以创建用于加载，生长和/或收集细胞的自定义任务。 定制任务可以包括一个或多个步骤，其中用户可以根据需要添加或省略步骤。 可以为与定制任务相关联的设置输入数据，其中实施例提供每次执行定制任务时输入的数据。 在另一个实施例中，可以配置用于定制任务的设置，其中可以在选择定制任务时存储和取回这些设置。 自定义任务的自定义和配置可以使用单元展开系统的图表视图进行，其中过程设置与图形用户界面元素相关联。

    CUSTOMIZABLE METHODS AND SYSTEMS OF GROWING AND HARVESTING CELLS IN A HOLLOW FIBER BIOREACTOR SYSTEM
    8.
    发明申请
    CUSTOMIZABLE METHODS AND SYSTEMS OF GROWING AND HARVESTING CELLS IN A HOLLOW FIBER BIOREACTOR SYSTEM 审中-公开
    中空纤维生物反应器系统生长和收集细胞的可定制方法和系统

    公开(公告)号：WO2012048276A2

    公开(公告)日：2012-04-12

    申请号：PCT/US2011/055453

    申请日：2011-10-07

    Applicant: CARIDIANBCT, INC. ,  STANTON, Edward, Allan, IV ,  ANTWILER, Glen, Delbert ,  HOWLEY, Patrick, J. ,  KINZIE, Michael, E. ,  DODD, Jon, A. ,  MEDINA, Casey V.

    Inventor： STANTON, Edward, Allan, IV ,  ANTWILER, Glen, Delbert ,  HOWLEY, Patrick, J. ,  KINZIE, Michael, E. ,  DODD, Jon, A. ,  MEDINA, Casey V.

    IPC: C12N5/00

    CPC classification number: C12M41/44 ,  C12M23/42 ,  C12M23/44 ,  C12M25/10 ,  C12M25/12 ,  C12M29/16 ,  C12M29/20 ,  C12M41/48 ,  G06F8/38

    Abstract: Embodiments described herein generally relate to methods and systems for customizing protocols for use with a cell expansion system. Through a user interface, a user may create a custom task for loading, growing and/or harvesting cells. A custom task may comprise one or more steps, in which a user may add or omit steps, as desired. Data may be entered for settings associated with a custom task, in which embodiments provide for such data to be entered each time the custom task is performed. In another embodiment, the settings for a custom task may be configured, in which such settings may be stored and retrieved upon selection of the custom task. Customization and configuration of a custom task may occur using a diagram view of the cell expansion system, in which process settings are associated with graphical user interface elements.

    Abstract translation: 本文描述的实施例通常涉及用于定制用于细胞扩增系统的协议的方法和系统。 通过用户界面，用户可以创建用于加载，增长和/或收获单元的自定义任务。 自定义任务可以包括一个或多个步骤，其中用户可以根据需要添加或省略步骤。 可以为与自定义任务相关联的设置输入数据，其中实施例提供每当执行自定义任务时输入这样的数据。 在另一个实施例中，可以配置自定义任务的设置，其中可以在选择自定义任务时存储和检索这样的设置。 自定义任务的定制和配置可以使用单元扩展系统的图视图进行，其中过程设置与图形用户界面元素相关联。

    ROTATION SYSTEM FOR CELL GROWTH CHAMBER OF A CELL EXPANSION SYSTEM AND METHOD OF USE THEREFOR
    9.
    发明申请
    ROTATION SYSTEM FOR CELL GROWTH CHAMBER OF A CELL EXPANSION SYSTEM AND METHOD OF USE THEREFOR 审中-公开
    细胞扩增系统的细胞生长室的旋转系统及其使用方法

    公开(公告)号：WO2010096312A1

    公开(公告)日：2010-08-26

    申请号：PCT/US2010/023750

    申请日：2010-02-10

    Applicant: CARIDIANBCT, INC. ,  LEUTHAEUSER, Paul M. ,  DODD, Jon A. ,  DILORENZO, Thomas G.

    Inventor： LEUTHAEUSER, Paul M. ,  DODD, Jon A. ,  DILORENZO, Thomas G.

    IPC: C12M3/04 ,  C12M3/06

    CPC classification number: C12M23/50 ,  B01F11/00 ,  B01F11/0005 ,  C12M23/42 ,  C12M23/48 ,  C12M25/10 ,  C12M25/12 ,  C12M27/10 ,  C12M27/14 ,  C12M27/16 ,  C12N5/0068

    Abstract: A system and method for rotating a cell growth chamber of a cell expansion system includes a rotatable member for engaging a chamber coupling attached to the cell growth chamber. The rotatable member includes an independently operable mechanism for engaging a rotatable fitting associated with the chamber coupling. In at least one embodiment, the chamber coupling is selectively rotatable by turning the rotatable member, thereby rotating the cell growth chamber around a first axis. The cell growth chamber is also selectively rotatable around a second axis by turning the rotatable fitting associated with the chamber coupling. Other novel aspects include a way of attaching the cell growth chamber to the shaft assembly, and a new tube routing clip.

    Abstract translation: 用于旋转电池膨胀系统的电池生长室的系统和方法包括用于接合附接到电池生长室的室耦合的可旋转构件。 可旋转构件包括用于接合与腔室联接器相关联的可旋转配件的可独立操作的机构。 在至少一个实施例中，通过转动可旋转构件来选择性地旋转室联接器，从而使细胞生长室围绕第一轴线旋转。 通过转动与腔室联接件相关联的可旋转配件，细胞生长室也可以围绕第二轴线选择性地旋转。 其他新颖的方面包括将细胞生长室附接到轴组件的方式和新的管路径夹。

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