公开(公告)号：WO9845456A8

公开(公告)日：2000-02-17

申请号：PCT/EP9802069

申请日：1998-04-09

Applicant: IPK GATERSLEBEN ,  SONNEWALD UWE ,  EBNETH MARCUS

Inventor： SONNEWALD UWE ,  EBNETH MARCUS

IPC: C12N9/16 ,  C12N15/82

CPC classification number: C12N9/16 ,  C12N15/8209

Abstract: The invention relates to recombinant DNA molecules containing a DNA sequence coding a protein with the biological activity of a 2-deoxyglucose-6-phosphate (2-DOG-6-P) phosphatase and controlled by regulatory sequences of a promoter and transcription, termination and/or polyadenylation signals active in plants. The invention further relates to vectors and host cells containing inventive recombinant DNA molecules. Also disclosed are methods for producing transformed plants cells and plants using the inventive recombinant DNA molecules and vectors. The invention also relates to transgenic plants, their crops and propagation materials and to plants cells and tissues containing inventive recombinant DNA molecules or produced according to the inventive method.

Abstract translation: 它描述了含有编码具有2-脱氧葡萄糖-6-磷酸（2-DOG-6-P）磷酸酶的生物活性和调节序列的控制下的一个的蛋白质的DNA序列的重组DNA分子 矗立在植物活性启动子和转录终止和/或聚腺苷酸化信号。 此外，载体和宿主细胞中，其包括所述新颖的重组DNA分子。 此外，使用所描述的重组DNA分子和载体提供了制备转化的植物细胞和植物的方法。 此外，转基因植物，其繁殖材料和收获的产品，以及植物细胞和组织中描述的是包括在内，新的重组DNA分子或载体或由本发明方法生产的。

公开(公告)号：WO2005098015A2

公开(公告)日：2005-10-20

申请号：PCT/EP2005/003297

申请日：2005-03-30

Applicant: METANOMICS GMBH & CO. KGAA ,  EBNETH, Marcus ,  PUZIO, Piotr ,  BLAU, Astrid ,  WALK, Tilmann B. ,  HAAKE, Volker ,  DÄSCHNER, Klaus ,  PLESCH, Gunnar

Inventor： EBNETH, Marcus ,  PUZIO, Piotr ,  BLAU, Astrid ,  WALK, Tilmann B. ,  HAAKE, Volker ,  DÄSCHNER, Klaus ,  PLESCH, Gunnar

IPC: C12P13/00

CPC classification number: C12N15/8253 ,  C07K14/415

Abstract: The present invention relates to a process for the production of methionine in an organism such as a microorgansm, a non-human animal or plant. The invention furthermore relates to nucleic acid molecules, polypeptides, nucleic acid constructs, vectors, antisense molecules, antibodies, host cells, plant tissue, propagtion material, harvested material, plants, microorganisms as well as agricultural compositions and to their use.

Abstract translation: 本发明涉及在微生物，非人动物或植物等生物体中生产甲硫氨酸的方法。 本发明还涉及核酸分子，多肽，核酸构建体，载体，反义分子，抗体，宿主细胞，植物组织，繁殖材料，收获的材料，植物，微生物以及农业组合物及其用途。

公开(公告)号：WO0112827A9

公开(公告)日：2002-05-10

申请号：PCT/EP0007807

申请日：2000-08-10

Applicant: SUNGENE GMBH & CO KGAA ,  EBNETH MARCUS ,  HERBERS KARIN ,  GEIGER MICHAEL ,  SAALBACH ISOLDE

Inventor： EBNETH MARCUS ,  HERBERS KARIN ,  GEIGER MICHAEL ,  SAALBACH ISOLDE

IPC: C12N1/21 ,  C12N9/02 ,  C12N15/53 ,  C12N15/82 ,  C12P17/06 ,  A01H5/00 ,  C07D311/72

CPC classification number: C12N9/0069 ,  C12N15/8243 ,  C12N15/825 ,  C12P17/06

Abstract: The invention relates to a new type of expression cassettes which, under genetic control, contain regulating nucleic acid sequences a) nucleic acid sequence coding for 4-hydrophenylpyruvate dioxygenase (HPPD) or for one of its functional equivalents; and/or b) at least one nucleic acid sequence (anti-HGD), which can inhibit the homogentisate-dioxygenase (HGD) activity. The invention also relates to vectors which are suitable for the production of plants having an increased tocopherol content, to transgenic plants produced therewith, and to a method for the production of transgenic plants having an increased tocopherol content.

Abstract translation: 本发明涉及新的表达盒，其包含，调节核酸序列的遗传控制下a）用于4-羟基苯双加氧酶（HPPD）或其功能等价物的编码核酸序列; 和/或b）至少一种核酸序列（抗HGD），其HGD），其能够（以抑制尿双加氧酶，以及其适合于生产植物的许多载体活性具有增加的生育酚含量，由此产生的转基因植物 及用于生产转基因植物的方法具有增加的生育酚含量。

公开(公告)号：WO1998018940A1

公开(公告)日：1998-05-07

申请号：PCT/EP1997005900

申请日：1997-10-24

Applicant: BASF AKTIENGESELLSCHAFT ,  SONNEWALD, Uwe ,  EBNETH, Marcus ,  SCHMIDT, Ralf-Michael

Inventor： BASF AKTIENGESELLSCHAFT

IPC: C12N15/55

CPC classification number: C12N15/8225 ,  C12N15/8222 ,  C12N15/8234

Abstract: Promoters are disclosed which cause the permanent, leaf-specific expression of a coding nucleotide sequence controlled by said promoters, for example a sequence which confers a specific resistance or increases the photosynthesis capacity.

Abstract translation: 本发明涉及启动子在由它们编码的核苷酸序列，所控制的永久植物，叶特异性表达该效果如赋予抗性或增加的光合效率的序列。

公开(公告)号：WO2005098015A3

公开(公告)日：2006-07-20

申请号：PCT/EP2005003297

申请日：2005-03-30

Applicant: METANOMICS GMBH ,  EBNETH MARCUS ,  PUZIO PIOTR ,  BLAU ASTRID ,  WALK TILMANN B ,  HAAKE VOLKER ,  DAESCHNER KLAUS ,  PLESCH GUNNAR

Inventor： EBNETH MARCUS ,  PUZIO PIOTR ,  BLAU ASTRID ,  WALK TILMANN B ,  HAAKE VOLKER ,  DAESCHNER KLAUS ,  PLESCH GUNNAR

IPC: C12N15/82 ,  C07K14/415 ,  C12P13/00

CPC classification number: C12N15/8253 ,  C07K14/415

Abstract: The present invention relates to a process for the production of methionine in an organism such as a microorgansm, a non-human animal or plant. The invention furthermore relates to nucleic acid molecules, polypeptides, nucleic acid constructs, vectors, antisense molecules, antibodies, host cells, plant tissue, propagtion material, harvested material, plants, microorganisms as well as agricultural compositions and to their use.

Abstract translation: 本发明涉及在微生物，非人动物或植物等生物体中生产甲硫氨酸的方法。 本发明还涉及核酸分子，多肽，核酸构建体，载体，反义分子，抗体，宿主细胞，植物组织，繁殖材料，收获的材料，植物，微生物以及农业组合物及其用途。

公开(公告)号：WO2004074440A2

公开(公告)日：2004-09-02

申请号：PCT/US2004/004422

申请日：2004-02-13

Applicant: METANOMICS GMBH & CO. KGAA ,  PLESCH, Gunnar ,  CHARDONNENS, Agnes ,  SCHMITZ, Oliver ,  PUZIO, Piotr ,  EBNETH, Marcus ,  WANG, Xi-Qing

Inventor： PLESCH, Gunnar ,  CHARDONNENS, Agnes ,  SCHMITZ, Oliver ,  PUZIO, Piotr ,  EBNETH, Marcus ,  WANG, Xi-Qing

IPC: C12N

CPC classification number: C07K14/415 ,  C12N15/8261 ,  C12N15/8271 ,  Y02A40/146

Abstract: A method for preparing a nonhuman organism with faster growth and/or increased yield in comparison with a reference organism, which method comprises increasing the activity of L450 in said organism or in one or parts thereof in comparison with a reference organism.

Abstract translation: 与参考生物体相比，制备具有更快生长和/或增加的产量的非人体生物体的方法，该方法包括增加所述生物体中L450的活性，或者与参考生物体相比增加其一种或多种的活性。

公开(公告)号：WO2003102198A1

公开(公告)日：2003-12-11

申请号：PCT/EP2003/005668

申请日：2003-05-30

Applicant: METANOMICS GMBH & CO. KGAA ,  PLESCH, Gunnar ,  EBNETH, Marcus

Inventor： PLESCH, Gunnar ,  EBNETH, Marcus

IPC: C12N15/82

CPC classification number: C12N15/8216

Abstract: Die vorliegende Erfindung betrifft ein Verfahren zur stabilen Expression von nukleinsäuren in transgenen Pflanzen unter der kontrolle eines Petersilie-Ubiquitin -Promoters (PCUbi4-2). Dieser aus Petersilie (Petroselinum crispum) isolierte Promoter zeigt in fast allen transgenen Pflanzen eine starke konstitutive Epxression in nahezu allen pflanzlichen Geweben einschliesslich der Samen. Er enthält unter anderem ein mögliches Hitzeschock induzierbares Element (HSE). Weiterhin betrifft die Erfindung Nukleinsäurekonstrukte, Vektoren, transgene Pflanzen sowie die Verwendung dieser transgenen Pflanzen zur Herstellung von Nahrungs-, Futtermitteln, Saatgut, Pharmazeutika oder Feinchemikalien.

Abstract translation: 本发明涉及一种用于在转基因植物欧芹泛素-Promoters（PcUbi4-2）的控制下的核酸的稳定表达的方法。 分离的启动子本欧芹（欧芹）示出了在几乎所有的转基因植物在几乎所有的植物组织包括种子强组成Epxression。 据载，除其他外，可能的热休克诱导元件（HSE）。 此外，本发明提供核酸构建体，载体，转基因植物和用于生产食品，饲料，种子，药物或者精细化学品而言的使用这些转基因植物的。

公开(公告)号：WO9906578A3

公开(公告)日：1999-04-22

申请号：PCT/GB9802023

申请日：1998-07-10

Applicant: ZENECA LTD ,  JEPSON IAN ,  EBNETH MARCUS ,  SONNEWALD UWE

Inventor： JEPSON IAN ,  EBNETH MARCUS ,  SONNEWALD UWE

IPC: A01H5/00 ,  C12N5/10 ,  C12N9/14 ,  C12N9/16 ,  C12N15/11 ,  C12N15/55 ,  C12N15/82 ,  C12Q1/68

CPC classification number: C12N9/16 ,  C12N9/14 ,  C12N15/8216 ,  C12N15/8217 ,  C12N15/8222 ,  C12N15/8238 ,  C12N15/8245

Abstract: This invention relates to a method of controlling sprout formation in plants and parts thereof including vegetative storage organs. The method involves the use of target and organ specific promoters to control expression of DNA sequences to inhibit sprouting. Sprouting is restored by switching on expression of DNA sequences using inducible promoter regions where sprouting may be controlled by, for example, application of an external chemical stimulus.

Abstract translation: 本发明涉及一种控制包括营养器官在内的植物及其部分的芽形成的方法。 该方法涉及使用靶标和器官特异性启动子来控制DNA序列的表达以抑制萌发。 通过使用诱导型启动子区域转换DNA序列的表达来恢复萌芽，其中发芽可以通过例如施加外部化学刺激来控制。

公开(公告)号：WO2008034648A8

公开(公告)日：2008-08-14

申请号：PCT/EP2007053344

申请日：2007-04-04

Applicant: METANOMICS GMBH ,  PUZIO PIOTR ,  BLAU ASTRID ,  WALK TILMANN B ,  GIPMANS MARTIJN ,  HAAKE VOLKER ,  WEIG ALFONS ,  PLESCH GUNNAR ,  EBNETH MARCUS

Inventor： PUZIO PIOTR ,  BLAU ASTRID ,  WALK TILMANN B ,  GIPMANS MARTIJN ,  HAAKE VOLKER ,  WEIG ALFONS ,  PLESCH GUNNAR ,  EBNETH MARCUS

IPC: C12P13/12 ,  A01H5/00 ,  C07K14/415 ,  C07K16/16 ,  C12N1/21 ,  C12N15/11 ,  C12N15/82 ,  C12Q1/68

CPC classification number: C12N15/8243 ,  C12N15/8218 ,  C12N15/8253 ,  C12P13/12 ,  C12Y101/01085

Abstract: The present invention relates to a process for the production of a fine chemical in an organism such as a microorganism, a non-human animal or plant, or in a part thereof. The invention furthermore relates to nucleic acid molecules, antisense, RNAi, snRNA, dsRNA, siRNA, miRNA, ta-siRNA, cosuppression molecule, or ribozyme molecules, or polypeptides, nucleic acid constructs, vectors, antibodies, host cells, plant tissue, propagation material, harvested material, plants, microorganisms as well as agricultural compositions and to their use.

Abstract translation: 本发明涉及在微生物，非人动物或植物或其一部分的生物体中生产精细化学品的方法。 本发明还涉及核酸分子，反义RNAi，snRNA，dsRNA，siRNA，miRNA，ta-siRNA，共抑制分子或核酶分子或多肽，核酸构建体，载体，抗体，宿主细胞，植物组织，繁殖 材料，收获的材料，植物，微生物以及农业组合物及其用途。

公开(公告)号：WO2008034648A1

公开(公告)日：2008-03-27

申请号：PCT/EP2007/053344

申请日：2007-04-04

Applicant: METANOMICS GMBH ,  PUZIO, Piotr ,  BLAU, Astrid ,  WALK, Tilmann, B. ,  GIPMANS, Martijn ,  HAAKE, Volker ,  WEIG, Alfons ,  PLESCH, Gunnar ,  EBNETH, Marcus

Inventor： PUZIO, Piotr ,  BLAU, Astrid ,  WALK, Tilmann, B. ,  GIPMANS, Martijn ,  HAAKE, Volker ,  WEIG, Alfons ,  PLESCH, Gunnar ,  EBNETH, Marcus

IPC: C12P13/12 ,  C12N15/82 ,  C12N15/11 ,  C07K14/415 ,  C12N1/21 ,  C12Q1/68 ,  A01H5/00 ,  C07K16/16

CPC classification number: C12N15/8243 ,  C12N15/8218 ,  C12N15/8253 ,  C12P13/12 ,  C12Y101/01085

Abstract: The present invention relates to a process for the production of a fine chemical in an organism such as a microorganism, a non-human animal or plant, or in a part thereof. The invention furthermore relates to nucleic acid molecules, antisense, RNAi, snRNA, dsRNA, siRNA, miRNA, ta-siRNA, cosuppression molecule, or ribozyme molecules, or polypeptides, nucleic acid constructs, vectors, antibodies, host cells, plant tissue, propagation material, harvested material, plants, microorganisms as well as agricultural compositions and to their use.

Abstract translation: 本发明涉及在生物体如微生物，非人类动物或植物或其部分中生产精细化学品的方法。 本发明还涉及核酸分子，反义RNAi，snRNA，dsRNA，siRNA，miRNA，ta-siRNA，共抑制分子或核酶分子或多肽，核酸构建体，载体，抗体，宿主细胞，植物组织，增殖 材料，收获材料，植物，微生物以及农业组合物及其用途。