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1.
公开(公告)号:WO2011143329A2
公开(公告)日:2011-11-17
申请号:PCT/US2011/036097
申请日:2011-05-11
Applicant: CV HOLDINGS, LLC , FELTS, John, T. , FISK, Thomas, E. , ABRAMS, Robert, S. , FERGUSON, John , FREEDMAN, Jonathan, R. , PANGBORN, Robert, J. , SAGONA, Peter, J.
Inventor: FELTS, John, T. , FISK, Thomas, E. , ABRAMS, Robert, S. , FERGUSON, John , FREEDMAN, Jonathan, R. , PANGBORN, Robert, J. , SAGONA, Peter, J.
CPC classification number: C23C16/50 , A61M5/31513 , B05D1/62 , B05D5/08 , B05D7/02 , B65D25/14 , C23C16/045 , C23C16/401 , C23C16/505 , C23C16/52 , C23C16/54 , G01N15/082 , G01N2033/0096 , Y10T428/24975 , Y10T428/31663
Abstract: A method for coating a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising an organosilicon precursor and optionally O 2 . The lubricity, hydrophobicity and/or barrier properties of the coating are set by setting the ratio of the O 2 to the organosilicon precursor in the gaseous reactant, and/or by setting the electric power used for generating the plasma. In particular, a lubricity coating made by said method is provided. Vessels coated by said method and the use of such vessels protecting a compound or composition contained or received in said coated vessel against mechanical and/or chemical effects of the surface of the uncoated vessel material are also provided.
Abstract translation: 提供了一种通过PECVD涂覆基底表面的方法,该方法包括从包含有机硅前体和任选的O 2的气态反应物产生等离子体。 通过设定气体反应物中的O 2与有机硅前体的比例和/或通过设定用于产生等离子体的电力来设定涂层的润滑性,疏水性和/或阻隔性。 特别地,提供了由所述方法制成的润滑性涂层。 还提供了通过所述方法涂覆的容器以及保护包含或接收在所述涂覆的容器中的化合物或组合物的这种容器的抗体对未涂覆的容器材料的表面的机械和/或化学作用。
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公开(公告)号:WO2010132591A3
公开(公告)日:2010-11-18
申请号:PCT/US2010/034586
申请日:2010-05-12
Applicant: CV Holdings, LLC , Felts, John T. , Fisk, Thomas E. , Abrams, Robert S. , Pangborn, Robert J. , Sagona, Peter J.
Inventor: Felts, John T. , Fisk, Thomas E. , Abrams, Robert S. , Pangborn, Robert J. , Sagona, Peter J.
IPC: C23C16/30 , H01L21/205 , C23C16/50 , C23C16/24 , C23C14/40
Abstract: A method for coating a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising an organosilicon precursor and optionally O2. The lubricity, hydrophobicity and/or barrier properties of the coating are set by setting the ratio of the O2 to the organosilicon precursor in the gaseous reactant, and/or by setting the electric power used for generating the plasma. In particular, a lubricity coating made by said method is provided. Vessels coated by said method and the use of such vessels protecting a compound or composition contained or received in said coated vessel against mechanical and/or chemical effects of the surface of the uncoated vessel material are also provided.
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公开(公告)号:WO2010132589A3
公开(公告)日:2011-03-31
申请号:PCT/US2010034582
申请日:2010-05-12
Applicant: CV HOLDINGS LLC , FISK THOMAS E , FERGUSON JOHN , FREEDMAN JONATHAN R
Inventor: FISK THOMAS E , FERGUSON JOHN , FREEDMAN JONATHAN R
IPC: G01N21/954 , A61J1/05 , G01N21/90 , G01N21/952
CPC classification number: C23C16/54 , A61M5/3129 , A61M2005/3131 , C23C16/045 , C23C16/503 , C23C16/52 , G01M3/26 , G01N21/9072 , G01N21/9081
Abstract: A method for inspecting the product of a coating process is provided. Therein, the release of at least one volatile species from the coated surface into the gas space adjacent to the coated surface is measured and the result is compared with the result for at least one reference object measured under the same test conditions. Thus the presence or absence of the coating, and/or a physical and/or chemical property of the coating can be determined. The method is useful for inspecting any coated articles, e.g. vessels. Its application on the inspection of PECVD coatings made from organosilicon precursors, especially of barrier coatings, is also disclosed.
Abstract translation: 提供了一种用于检查涂布工艺的产品的方法。 在此,测量至少一种挥发性物质从涂覆表面释放到与涂覆表面相邻的气体空间中,并将结果与在相同测试条件下测量的至少一个参考对象的结果进行比较。 因此,可以确定涂层的存在或不存在,和/或涂层的物理和/或化学性质。 该方法可用于检查任何涂层制品,例如, 船只。 还公开了其用于检查由有机硅前体,特别是阻隔涂层制成的PECVD涂层的应用。
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公开(公告)号:WO2010132581A2
公开(公告)日:2010-11-18
申请号:PCT/US2010/034571
申请日:2010-05-12
Applicant: CV HOLDINGS, LLC , Fisk, Thomas, E. , Felts, John, T. , Abrams, Robert, S.
Inventor: Fisk, Thomas, E. , Felts, John, T. , Abrams, Robert, S.
CPC classification number: C23C16/54 , A61M5/3129 , A61M2005/3131 , C23C16/045 , C23C16/503 , C23C16/52 , G01M3/26 , G01N21/9072 , G01N21/9081
Abstract: A vessel processing system for coating and inspection of a vessel is disclosed, the system comprising a processing station arrangement configured for performing a first inspection of the vessel for defects, application of a first coating to the interior surface of the vessel, performing a second inspection of the interior surface of the coated vessel for defects and evaluating the data acquired during inspection, wherein the second inspection and the data evaluation takes less than 30 seconds.
Abstract translation: 公开了一种用于容器的涂覆和检查的容器处理系统,该系统包括处理站装置,该处理站装置构造成用于对容器进行缺陷的第一次检查,将第一涂层施加到容器的内表面,执行第二次检查 的涂层容器的内表面用于缺陷并评估在检查期间获取的数据,其中第二检查和数据评估花费少于30秒。
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公开(公告)号:WO2012125736A2
公开(公告)日:2012-09-20
申请号:PCT/US2012/029089
申请日:2012-03-14
Applicant: SIO2 MEDICAL PRODUCTS, INC. , FISK, Thomas E.
Inventor: FISK, Thomas E.
IPC: A61M5/31
CPC classification number: G01L1/24 , A61M5/3129 , A61M5/347 , A61M5/5086 , A61M2005/3104 , A61M2205/0294 , A61M2205/6081
Abstract: A medical device comprising a wall, a coating of SiO x , and a piezochromic material is disclosed. The piezochromic material is associated with the wall, and changes its appearance when the wall is exposed to mechanical stress exceeding a threshold intensity. Also disclosed is a method of interrogating a closed medical device for processing damage, comprising at least the acts of providing a closed medical device and inspecting the medical device. The medical device is inspected from the exterior for a change in the appearance of at least some of its piezochromic material that is characteristic of exposure of the wall to mechanical stress exceeding a threshold intensity greater than zero. Optionally in any embodiment inspecting is carried out using a spectrophotometer to determine the change in the color of at least some of its piezochromic material.
Abstract translation: 公开了包括壁,SiOx涂层和压敏变色材料的医疗装置。 压电变色材料与壁相关联,并且当壁暴露于超过阈值强度的机械应力时改变其外观。 还公开了询问用于处理损伤的封闭式医疗装置的方法,至少包括提供封闭的医疗装置和检查医疗装置的动作。 医疗设备从外部检查其至少一些其压电色素材料的外观变化,其特征在于壁的机械应力超过超过零的阈值强度。 可选地,在任何实施例中,使用分光光度计进行检查以确定其压电色素材料的至少一些的颜色变化。
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公开(公告)号:WO2010132585A3
公开(公告)日:2011-03-31
申请号:PCT/US2010034577
申请日:2010-05-12
Applicant: CV HOLDINGS LLC , FELTS JOHN T , FISK THOMAS E , ABRAMS ROBERT S , SAGONA PETER J
Inventor: FELTS JOHN T , FISK THOMAS E , ABRAMS ROBERT S , SAGONA PETER J
CPC classification number: C23C16/54 , A61M5/3129 , A61M2005/3131 , C23C16/045 , C23C16/503 , C23C16/52 , G01M3/26 , G01N21/9072 , G01N21/9081
Abstract: A plasma enhanced chemical vapor deposition (PECVD) apparatus for coating an interior surface of a vessel is provided, the apparatus comprising a vessel holder comprising a vessel port configured to receive and seat a first opening of the vessel for processing the interior surface of the seated vessel via the vessel port, an inner electrode for being arranged within an interior space of the seated vessel, an outer electrode having an interior portion for receiving the seated vessel, and a power supply to create a plasma within the vessel, wherein the seated vessel and vessel holder are adapted for defining a plasma reaction chamber.
Abstract translation: 提供了一种用于涂覆容器的内表面的等离子体增强化学气相沉积(PECVD)装置,该装置包括容器保持器,该容器保持器包括容器端口,该容器端口构造成容纳和安置容器的第一开口, 容器,通过容器端口设置的内部电极,设置在就座容器的内部空间内的外部电极,具有用于容纳就座容器的内部部分的外部电极和用于在容器内产生等离子体的电源,其中所述就座容器 并且容器保持器适于限定等离子体反应室。
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公开(公告)号:WO2010132579A3
公开(公告)日:2011-03-31
申请号:PCT/US2010034568
申请日:2010-05-12
Applicant: CV HOLDINGS LLC , FISK THOMAS E , FELTS JOHN T , ABRAMS ROBERT S
Inventor: FISK THOMAS E , FELTS JOHN T , ABRAMS ROBERT S
CPC classification number: C23C16/54 , A61M5/3129 , A61M2005/3131 , C23C16/045 , C23C16/503 , C23C16/52 , G01M3/26 , G01N21/9072 , G01N21/9081
Abstract: A vessel processing system for coating of a vessel is provided, the system comprising: a first processing station configured for performing a first processing of an interior surface of the vessel, a second processing station spaced from the first processing station and configured for performing a second processing of the interior surface of the vessel, a vessel holder comprising a vessel port configured to receive and seat an opening of the vessel for processing the interior surface of the seated vessel via the vessel port at the first processing station and at the second processing station, and a conveyor arrangement for transporting the vessel holder and the seated vessel after the first processing from the first processing station to the second processing station for the second processing of the interior surface of the seated vessel at the second processing station.
Abstract translation: 提供了一种用于涂覆容器的容器处理系统,该系统包括:第一处理站,被配置为执行容器的内表面的第一处理;第二处理站,与第一处理站间隔开并且被配置为执行第二处理站 处理容器的内表面的容器保持器,容器保持器包括容器端口,该容器端口构造成容纳和安置容器的开口,用于经由第一处理站处的容器端口和第二处理站处理就座容器的内表面 以及传送装置,用于在第一处理站之后将容器保持器和就座容器从第一处理站传送到第二处理站,用于在第二处理站处对就座容器的内表面进行第二次处理。
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公开(公告)号:WO2010132579A2
公开(公告)日:2010-11-18
申请号:PCT/US2010/034568
申请日:2010-05-12
Applicant: CV HOLDINGS, LLC , Fisk, Thomas, E. , Felts, John, T. , Abrams, Robert, S.
Inventor: Fisk, Thomas, E. , Felts, John, T. , Abrams, Robert, S.
CPC classification number: C23C16/54 , A61M5/3129 , A61M2005/3131 , C23C16/045 , C23C16/503 , C23C16/52 , G01M3/26 , G01N21/9072 , G01N21/9081
Abstract: A vessel processing system for coating of a vessel is provided, the system comprising: a first processing station configured for performing a first processing of an interior surface of the vessel, a second processing station spaced from the first processing station and configured for performing a second processing of the interior surface of the vessel, a vessel holder comprising a vessel port configured to receive and seat an opening of the vessel for processing the interior surface of the seated vessel via the vessel port at the first processing station and at the second processing station, and a conveyor arrangement for transporting the vessel holder and the seated vessel after the first processing from the first processing station to the second processing station for the second processing of the interior surface of the seated vessel at the second processing station.
Abstract translation: 提供了一种用于涂覆容器的容器处理系统,该系统包括:第一处理站,被配置为执行容器的内表面的第一处理;第二处理站,与第一处理站间隔开并被配置为执行第二处理站 处理容器的内表面的容器保持器,容器保持器包括容器端口,该容器端口构造成容纳和安置容器的开口,用于经由第一处理站处的容器端口和第二处理站处理就座容器的内表面 以及传送装置,用于在第一处理站之后将容器保持器和就座容器从第一处理站传送到第二处理站,用于在第二处理站处对待命容器的内表面进行第二次处理。
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公开(公告)号:WO2014052792A1
公开(公告)日:2014-04-03
申请号:PCT/US2013/062247
申请日:2013-09-27
Applicant: SIO2 MEDICAL PRODUCTS, INC. , RESNICK, Paul R. , FISK, Thomas E. , WEIKART, Christopher
Inventor: RESNICK, Paul R. , FISK, Thomas E. , WEIKART, Christopher
CPC classification number: A61M5/31513 , A61J1/06 , A61M2005/3131 , A61M2207/00 , A61M2207/10 , C23C16/045 , C23C16/401
Abstract: A container, for example a syringe, cartridge, vial or similar article including a barrel or other vessel and a stopper, O-ring, plunger tip or piston. The vessel substrate defines a lumen and an internal sliding surface on the vessel substrate adjacent to the lumen. The stopper, O-ring, plunger tip or piston has an external sliding surface slidable in the lumen at least substantially in contact with the internal sliding surface. The internal sliding surface, the external sliding surface, or both are made at least in part of a parylene or halogenated polymer, which can be in the form of a coating or a bulk material. Methods of making the syringe, cartridge, or similar article using chemical vapor deposition, as by depositing the parylene or halogenated polymer directly or with intervening layers to define the external sliding surface, the internal internal sliding surface, or both are disclosed.
Abstract translation: 容器,例如注射器,药筒,小瓶或类似物品,其包括镜筒或其他容器和塞子,O形环,柱塞尖端或活塞。 容器衬底限定了与腔相邻的容器衬底上的管腔和内部滑动表面。 止动器O形环,柱塞尖端或活塞具有可在内腔中滑动至少基本上与内部滑动表面接触的外部滑动表面。 内部滑动表面,外部滑动表面或两者均至少部分由聚对二甲苯或卤化聚合物制成,其可以是涂层或散装材料的形式。 公开了通过使用化学气相沉积来制造注射器,药筒或类似物品的方法,如通过直接或间接沉积聚对二甲苯或卤化聚合物以限定外部滑动表面,内部内部滑动表面或两者。
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10.
公开(公告)号:WO2013170052A1
公开(公告)日:2013-11-14
申请号:PCT/US2013/040380
申请日:2013-05-09
Applicant: SIO2 MEDICAL PRODUCTS, INC. , FELTS, John, T. , FISK, Thomas, E. , ABRAMS, Robert, S. , FERGUSON, John , FREEDMAN, Jonathan, R. , PANGBORN, Robert, J. , SAGONA, Peter , WEIKART, Christopher , ISRAELACHVILI, Jacob
Inventor: FELTS, John, T. , FISK, Thomas, E. , ABRAMS, Robert, S. , FERGUSON, John , FREEDMAN, Jonathan, R. , PANGBORN, Robert, J. , SAGONA, Peter , WEIKART, Christopher , ISRAELACHVILI, Jacob
CPC classification number: A61J1/1468 , A61J1/00 , A61J1/05 , A61J1/2096 , A61J2200/50 , A61L31/10 , A61L2400/10 , A61L2420/08 , A61M3/0262 , Y10T428/1383
Abstract: A method for providing a saccharide based lubricating or protective coating or layer on a substrate surface is provided. In particular, a lubricity and/or protective coating or layer made by said method is provided. Pharmaceutical packages or other vessels coated by said method and the use of such pharmaceutical packages or other vessels protecting a compound or composition contained or received in said vessel with a protective coating against mechanical and/or chemical effects of the surface of the vessel without a protective coating material are also provided.
Abstract translation: 提供了一种在基材表面上提供基于糖的润滑或保护涂层或层的方法。 特别地,提供了由所述方法制成的润滑性和/或保护性涂层或层。 通过所述方法涂覆的药物包装或其它容器以及使用这种药物包装或其他容器保护含有或接收在所述容器中的化合物或组合物的保护性涂层免受容器表面的机械和/或化学作用而没有保护 还提供涂料。
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