公开(公告)号：WO2003049837A1

公开(公告)日：2003-06-19

申请号：PCT/DK2002/000851

申请日：2002-12-12

Applicant: FOSS ELECTRIC A/S ,  JENSEN, Bent

Inventor： JENSEN, Bent

IPC: B01D29/01

CPC classification number: B01D37/00 ,  B01D29/01 ,  B01D29/86 ,  B01D29/94 ,  B01D35/26

Abstract: A sampling and filtering device having a circular chamber 14 and a wing 20 for rotating the fluid in the chamber, an inlet in the centre of the chamber, and a first outlet to waste at the periphery of the chamber, a woven filter 24, securely fastened between the rims of a filter housing and a removable wall and supported by a grooved collector plate forming the removable wall 40 in the filter housing 14. The inlet and outlet are controlled by valves (16, 18), so that the filter chamber 14, the wing 20, the open inlet, and open outlet may function as a centrifugal pump. The filter 24 is cleaned by the rotating wing 20. The device enables a fast extraction of a series of samples from grape juices provided from different batches or truck-loads of grapes during the grape harvest.

Abstract translation: 采样和过滤装置具有圆形室14和用于旋转腔室中的流体的翼片20，腔室中心的入口以及在腔室周围浪费的第一出口，编织过滤器24，牢固地 紧固在过滤器壳体的边缘和可移除的壁之间，并由形成在过滤器壳体14中的可移除壁40的带槽集电板支撑。入口和出口由阀（16,18）控制，使得过滤室14 翼20，开口和开口可用作离心泵。 过滤器24由旋转翼20清洁。该装置能够在葡萄收获期间从不同批次或卡车装载葡萄汁中提取的葡萄汁中快速提取一系列样品。

公开(公告)号：WO1996018089A1

公开(公告)日：1996-06-13

申请号：PCT/DK1995000492

申请日：1995-12-07

Applicant: FOSS ELECTRIC A/S ,  ANDERSEN, Hans, Villemoes

Inventor： FOSS ELECTRIC A/S

IPC: G01J03/28

CPC classification number: G01J3/45 ,  G01J3/453

Abstract: A method is suggested for obtaining information on the electromagnetic spectrum of a sample, the method comprising (a) generating a plurality of substantially identical signals, (b) determining the shape of a first number of the signals by performing a first number of scans of a first range of signal width, (c) determining the shape of a second number of the signals by performing a second number of scans of a second range of signal width, the second range being comprised by the first range and comprising a portion of the first range in which the signals have maximum absolute amplitude, (d) combining data from the first number of scans and the second number of scans so as to obtain data corresponding to the shape of the signals, and (e) performing a mathematical transformation of the combined data so as to obtain the information on the electromagnetic spectrum of the sample. According to this method, the electromagnetic spectrum - and especially an absorption spectrum for use in quantitative analysis of the sample - may be obtained faster than is possible using prior art methods.

Abstract translation: 提出了一种用于获得关于样本的电磁频谱的信息的方法，所述方法包括（a）产生多个基本相同的信号，（b）通过执行第一数量的扫描来确定第一数量的信号的形状 信号宽度的第一范围，（c）通过执行信号宽度的第二范围的第二数量的扫描来确定第二数量的信号的形状，所述第二范围包括所述第一范围并且包括所述第一范围 信号具有最大绝对幅度的第一范围，（d）组合来自第一扫描次数和第二扫描次数的数据，以获得对应于信号形状的数据，以及（e）执行数学变换 组合数据，以获得关于样品的电磁谱的信息。 根据该方法，可以比现有技术方法更快地得到电磁波谱，特别是用于样品定量分析的吸收光谱。

公开(公告)号：WO1995025174A1

公开(公告)日：1995-09-21

申请号：PCT/DK1995000119

申请日：1995-03-16

Applicant: FOSS ELECTRIC A/S ,  ÆGIDIUS, Poul, Erik

Inventor： FOSS ELECTRIC A/S

IPC: C12Q01/04

CPC classification number: C12Q1/04 ,  C12Q2304/12 ,  G01N2333/21 ,  Y10S435/874 ,  Y10S435/876 ,  Y10S435/968 ,  Y10S436/80 ,  Y10T436/104165

Abstract: A method is disclosed for conditioning samples (of e.g. milk or meat) containing fat globules and somatic cells and/or protein particles before they are subjected to fluorescence measurements in order to determine the bacterial content, as well as methods for performing the determination of bacterial content in such samples. The conditioning method involves the treatment of the samples with a ion-chelating agent, a proteolytic enzyme, a detergent, and a bacteriologically specific fluorochrome such as ethidium bromide. Detergent is used in a concentration resulting in substantially no dissolution of the fat globules and the conditioned samples thus loses insignificant amounts of fat globules. The assessment of fluorescence is preferably performed in a conventional flow cytometer. As no separation of fat globules is necessary, the methods are simple and fast. The bacterial determinations have proved reliable when compared to standard methods.

Abstract translation: 公开了一种用于调节含有脂肪球和体细胞和/或蛋白质颗粒的样品（例如牛奶或肉）的方法，然后进行荧光测量以确定细菌含量，以及进行细菌测定的方法 这些样品中的含量。 调理方法包括用离子螯合剂，蛋白水解酶，洗涤剂和细菌特异性荧光染料如溴化乙锭处理样品。 洗涤剂的使用浓度导致脂肪球基本上不溶解，并且调理的样品因此失去微量的脂肪球。 荧光的评估优选在常规流式细胞仪中进行。 由于不需要分离脂肪球，所以方法简便快捷。 与标准方法相比，细菌测定证明是可靠的。

公开(公告)号：WO1998020338A1

公开(公告)日：1998-05-14

申请号：PCT/DK1997000492

申请日：1997-10-31

Applicant: FOSS ELECTRIC A/S ,  FRANDSEN, Andreas, Skærlund ,  PEDERSEN, Soren, Christian ,  RIDDER, Carsten ,  THOMSEN, Henrik

Inventor： FOSS ELECTRIC A/S

IPC: G01N33/04

CPC classification number: G01N21/05 ,  G01N21/0303 ,  G01N21/3577 ,  G01N21/359 ,  G01N33/04 ,  G01N2021/0346 ,  G01N2021/0378

Abstract: The present invention relates to an on-line method and a flow system as well as a cuvette for carrying out IR spectrometry for analysis of liquid food products, possibly containing dissolved gases, in a process line in a liquid food product processing plant, especially a dairy processing milk and milk products. A liquid sample is extracted from the process line to a measuring branch, the sample is thermostated and passed to a measurement cuvette. The IR-absorbance spectrum is measured, e.g. in the MID-IR or NIR-range. In order to obtain an on-line monitoring of the process line the liquid food sample is extracted directly from the process line into the measurement branch, in which the pressure is maintained at least as high as in the adjacent process line. The high pressure ensures that dissolved air will stay dissolved in the liquid food. Before each new sample the measurement branch and cuvette are flushed by high flow rates with a part of the new sample to clean the cuvette. The measurement cuvette has strong windows, preferably diamond windows to stand a high pressure and high flow rates. The on-line system is arranged to carry out e.g. 120 measurements per hour.

Abstract translation: 本发明涉及一种在线方法和流动系统以及用于在液体食品加工厂的生产线中进行用于分析可能含有溶解气体的液体食品的红外光谱分析的比色杯，特别是 乳制品加工牛奶和奶制品。 将液体样品从工艺线提取到测量分支，将样品恒温并通入测量试管。 测量IR吸收光谱。 在MID-IR或NIR范围内。 为了获得工艺线的在线监测，将液体食品样品直接从生产线提取到测量分支中，其中压力保持至少与相邻工艺线中一样高。 高压确保溶解的空气将保持溶解在液体食品中。 在每个新样品之前，用新的样品的一部分用高流量冲洗测量分支和比色皿以清洁比色皿。 测量比色皿具有很强的窗口，最好是金刚石窗，以承受高压和高流速。 在线系统被布置成执行例如。 每小时120次测量。

公开(公告)号：WO1998002720A1

公开(公告)日：1998-01-22

申请号：PCT/DK1997000299

申请日：1997-07-04

Applicant: FOSS ELECTRIC A/S ,  LARSEN, Hans

Inventor： FOSS ELECTRIC A/S

IPC: G01J03/45

CPC classification number: G01J3/453

Abstract: An interferometer for Fourier spectroscopy, wherein the interferometer comprises a beamsplitter (14) and two retroreflectors (20, 26), characterized in that the beamsplitter (14) is mounted movably, e.g., mounted pivotally or displacably, while both retroreflectors (20, 26) are arranged as fixed retroreflectors. The proposed structure is simple to produce, can be made substantially insensible to environmental vibrations, and it is well suited for routine measurements for the determination of quantities of predefined components in a medium. The interferometer is particularly intended for measurements in the mid- or near-infrared range for determination of the quantities of specified components in a medium, and more specifically in a food product, e.g., a liquid such as milk.

Abstract translation: 一种用于傅立叶光谱的干涉仪，其中所述干涉仪包括分束器（14）和两个后向反射器（20,26），其特征在于，分束器（14）可移动地安装，例如可枢转地或可置换地安装，同时两个回射器 ）被布置为固定的后向反射器。 所提出的结构生产简单，可以对环境振动基本上不敏感，并且非常适合用于确定介质中预定组分的量的常规测量。 该干涉仪特别用于在中等或近红外范围内的测量，用于确定介质中特定组分的量，更确切地说在食品中，例如液体如牛奶。

公开(公告)号：WO1997007390A1

公开(公告)日：1997-02-27

申请号：PCT/DK1996000351

申请日：1996-08-20

Applicant: FOSS ELECTRIC A/S ,  CHRISTENSEN, Steen, Kold ,  BORN, Christian ,  ASMUSSEN, Tove ,  LARSEN, Mogens, Bering

Inventor： FOSS ELECTRIC A/S

IPC: G01N15/14

CPC classification number: G01N15/1456 ,  G01N2015/1486 ,  G06M11/00

Abstract: A method and apparatus for determining the number of particles or cells in a liquid sample. The method comprises: a) determining the number of particles or cells in a first volume of the liquid sample, b) determining the statistical uncertainty of the determined number of particles in said first volume, c) if the determined uncertainty is larger than a predetermined value, determining the number of particles or cells in a further volume of the liquid sample, d) adding the numbers of cells or particles determined in steps a) and c), e) determining the statistical uncertainty of the number of particles determined in step d), f) repeating steps d) and e) with a further volume of the liquid sample, until the uncertainty determined in step e) is lower than said predetermined value or until a predetermined total volume of the liquid sample in which the number of cells or particles has been determined exceeds a predetermined volume being larger than said first volume. In this way, the volume examined and the uncertainty of the measurement may be selected so that a suitable compromise between the uncertainty and the time required to perform the measurement can be obtained. The apparatus according to the invention comprises a liquid flow system allowing the measurement sequence to be interrupted as soon as the calculating means decide that the uncertainty of the actual cell count is small enough to rely on the present determination. The apparatus will then be ready to carry on with the next sample, thereby maintaining a high capacity while obtaining reliable cell counts.

Abstract translation: 一种用于确定液体样品中的颗粒或细胞数量的方法和装置。 该方法包括：a）确定液体样品的第一体积中的颗粒或细胞的数量，b）确定所述第一体积中确定的颗粒数量的统计学不确定性，c）如果所确定的不确定度大于预定的 确定液体样品的另一体积中的颗粒或细胞的数量，d）添加在步骤a）和c）中确定的细胞或颗粒的数量，e）确定步骤中确定的颗粒数量的统计学不确定性 d），f）重复步骤d）和e）与另一体积的液体样品，直到在步骤e）中确定的不确定度低于所述预定值或直到

公开(公告)号：WO1996024832A1

公开(公告)日：1996-08-15

申请号：PCT/DK1996000068

申请日：1996-02-09

Applicant: FOSS ELECTRIC A/S ,  VILLEMOES, Andersen, Hans ,  KJÆR, Lisa ,  WAABEN, Hansen, Per ,  RIDDER, Carsten

Inventor： FOSS ELECTRIC A/S

IPC: G01N21/27

CPC classification number: G01J3/28 ,  G01J3/45 ,  G01N21/274

Abstract: A method for standardizing a spectrometer generating an optical spectrum from a sample, comprising generating at least one optical spectrum from at least one standardization sample each having a chemical composition resulting in the optical spectrum showing a characteristic pattern in a predetermined frequency range, comparing information relating to the pattern(s) to corresponding information relating to at least one reference pattern previously defined as the desired standard response from the at least one standardization sample, determining, based on the comparison, standardizing parameters describing the transition of the pattern(s) of the generated spectrum or spectra to the reference pattern(s) and storing said standardizing parameters in the spectrometer or a computer connected thereto, so that the spectrometer, when presented to an unknown sample, will, using the standardization parameters, generate an optical spectrum substantially identical to that which would be generated in a corresponding spectrometer standardized with a sample of the same chemical composition using the same previously defined reference pattern(s). The present method relates to standardization of the instrument to a well-defined state into which any number of instruments may be brought. In this state, calibrations may be transferred freely from instrument to instrument.

Abstract translation: 一种用于对从样品产生光谱的光谱仪进行标准化的方法，包括从至少一个标准化样品生成至少一个光谱，每个标准化样品具有导致光谱显示在预定频率范围内的特征图案的化学成分， 将所述模式转换为与至少一个参考模式有关的对应信息，所述至少一个参考模式先前被定义为来自所述至少一个标准化样本的期望标准响应，基于所述比较，确定描述所述模式 产生的光谱或参考图谱的光谱，并将所述标准化参数存储在光谱仪或与其连接的计算机上，使得当提供给未知样品时，光谱仪将使用标准化参数产生基本上 与在其中生成的相同 使用相同的先前定义的参考图案用相同化学成分的样品标准化的对应的光谱仪。 本方法涉及将仪器标准化到可以带有任何数量的仪器的明确定义的状态。 在这种状态下，校准可以从仪器自由传递给仪器。

公开(公告)号：WO1995016201A1

公开(公告)日：1995-06-15

申请号：PCT/DK1994000462

申请日：1994-12-09

Applicant: FOSS ELECTRIC A/S ,  ARNVIDARSON, Börkur ,  NYGAARD, Lars ,  HANSEN, Per, Waaben

Inventor： FOSS ELECTRIC A/S

IPC: G01N33/04

CPC classification number: G01N25/04 ,  G01N21/3577 ,  G01N33/04

Abstract: The present invention relates to a method for quantitatively assessing the amount of any extraneous water contained in a milk sample, the method comprising the steps of (a) performing a determination of the infrared (IR) attenuation of the sample in at least one waveband, (b) quantitatively assessing the amount of any extraneous water in the sample on the basis of the determination (a) and predetermined regression coefficients derived from multivariate calibration with respect to the relationship between infrared attenuation in the at least one waveband and the amount of extraneous water. The invention furthermore relates to a similar method for determining the freezing point depression of the sample. In addition, the invention relates to a method for the establishment of a set of regression coefficients for use in an instrument which determines the amount of extraneous water or the freezing point depression of a milk sample.

Abstract translation: 本发明涉及一种用于定量评估牛奶样品中所含的任何外来水量的方法，该方法包括以下步骤：（a）在至少一个波段中进行样品的红外（IR）衰减测定， （b）基于所述测定（a）和相对于所述至少一个波段中的红外衰减与所述至少一个波段的量之间的关系从多变量校准得出的预定回归系数，定量评估样品中的任何外来水量 水。 本发明还涉及用于确定样品的凝固点下降的类似方法。 此外，本发明涉及一种用于确定用于确定牛奶样品的外来水量或凝点降低的仪器中的一组回归系数的方法。

公开(公告)号：WO2003069331A1

公开(公告)日：2003-08-21

申请号：PCT/DK2003/000085

申请日：2003-02-10

Applicant: FOSS ELECTRIC A/S ,  PETERSEN, Poul, Erik ,  BENDTSEN, Anders, Broe

Inventor： BENDTSEN, Anders, Broe

IPC: G01N33/04

CPC classification number: G01N21/82 ,  G01N15/042 ,  G01N21/3577 ,  G01N33/04

Abstract: The content of casein in milk is determined by two measurements of infrared absorbance in a milk sample by infrared spectrometry before and after a separation of the casein. The casein content is calculated by use of absorbance data recorded during the two absorbance measurements. The new method is considerable faster than the known wet-chemical methods, such as the normal wet chemical reference method for casein determination in milk using a Kjeldahl nitrogen determination of the milk sample, then a coagulation of the milk, and finally a Kjeldahl nitrogen determination of the filtrate. Further the new method provides a more reliable accuracy than the know determination using a single infrared analysis of a milk sample.

Abstract translation: 牛奶中酪蛋白的含量通过红外光谱法在酪蛋白分离前后通过乳样品中的红外吸光度的两次测量来确定。 通过使用在两次吸光度测量期间记录的吸光度数据来计算酪蛋白含量。 新方法比已知的湿法化学方法快得多，例如使用牛奶样品的凯氏定氮测定乳中酪蛋白测定的正常湿化学参考方法，然后凝乳，最后进行凯氏定氮 的滤液。 此外，新方法提供比使用牛奶样品的单一红外分析的知道确定更可靠的精度。

公开(公告)号：WO2003100394A1

公开(公告)日：2003-12-04

申请号：PCT/DK2003/000355

申请日：2003-05-28

Applicant: FOSS ELECTRIC A/S ,  RIDDER, Carsten

Inventor： RIDDER, Carsten

IPC: G01N21/27

CPC classification number: G01N21/274

Abstract: The present invention relates to a method of determining a constituent of a sample and more specifically, to a method of correcting an absorbance value for a spectrometer. The method is especially applicable in connection with spectrometric analysis instruments for quantitatively determining the chemical composition of fluids, e.g. the content of fat, protein, lactose or urea, in food products, especially in raw milk or dairy products. The method is based upon a measurement of one or more selected ranges of a spectrum, providing an absorption spectrum of the product. The method may be applicable in connection with all spectroscopic instruments giving rise to specific ranges of a spectrum, such as UV, VIS, NIR, IR, NMR, MS, etc.). Typically, the spectrum will be a MID-IR absorption spectrum.

Abstract translation: 本发明涉及一种测定样品成分的方法，更具体地说，涉及校正光谱仪的吸光度值的方法。 该方法特别适用于光谱分析仪器，用于定量测定流体的化学成分，例如 食品中的脂肪，蛋白质，乳糖或尿素的含量，特别是生奶或乳制品中的含量。 该方法基于测量一个或多个选定的光谱范围，从而提供产物的吸收光谱。 该方法可以适用于产生光谱的特定范围的所有光谱仪，例如UV，VIS，NIR，IR，NMR，MS等）。 通常，光谱将是MID-IR吸收光谱。