公开(公告)号：JPS63305234A

公开(公告)日：1988-12-13

申请号：JP2213288

申请日：1988-02-03

Applicant: KETT ELECTRIC LAB ,  FUTREX INC

Inventor： ROBAATO DEIBITSUDO ROOZENTAARU ,  GUREEN KEISU ROOZENTAARU

IPC: G01J3/12 ,  G01N21/25 ,  G01N21/35

公开(公告)号：JPH08503773A

公开(公告)日：1996-04-23

申请号：JP51335094

申请日：1993-11-22

Applicant: FUTREX INC

Inventor： KRUEGER DON E JR ,  ROSENTHAL ROBERT D

IPC: A61B5/00 ,  A61B5/024 ,  G01N21/31 ,  G01N21/35 ,  G01N33/487

公开(公告)号：WO1994012866A1

公开(公告)日：1994-06-09

申请号：PCT/US1993011414

申请日：1993-11-22

Applicant: FUTREX, INC.

Inventor： FUTREX, INC. ,  KRUEGER, Don, E., Jr. ,  ROSENTHAL, Robert, D.

IPC: G01N21/35

CPC classification number: A61B5/02433 ,  A61B5/14532 ,  A61B5/14552 ,  G01N21/314 ,  G01N21/359

Abstract: A low cost means for increasing measurement sensitivity in LED/IRED near-infrared instruments is disclosed which utilizes a current modification means (27) for modifying the driving current supplied to each IRED (5) as a function of the opacity of the particular sample being measured. The current modification means is part of the processing means and comprises means for measuring a signal level (8) for each IRED at an analog-to-digital converter (10). Based upon the signal level detected for each IRED, the current modification means modifies the current to each IRED to a value that is as high as possible without saturating the analog-to-digital converter. Thus, by modifying the driving current of each IRED to such a maximal value, the analytical instrument of the present invention provides high resolution without the use of expensive electronic circuitry. Also provided is a system for generating and storing an optical signature of a particular user, thus further insuring the accuracy of measurements taken by the instrument.

Abstract translation: 公开了一种用于提高LED / IRED近红外仪器中的测量灵敏度的低成本手段，其利用当前修改装置（27）来修改提供给每个IRED（5）的驱动电流，作为特定样品的不透明度的函数 测量。 当前修改装置是处理装置的一部分，并且包括用于在模拟 - 数字转换器（10）处测量每个IRED的信号电平（8）的装置。 基于为每个IRED检测到的信号电平，当前修改装置将对每个IRED的电流修改为尽可能高的值，而不使模数转换器饱和。 因此，通过将每个IRED的驱动电流修改为这样的最大值，本发明的分析仪器在不使用昂贵的电子电路的情况下提供高分辨率。 还提供了一种用于生成和存储特定用户的光学签名的系统，从而进一步确保了仪器所进行的测量的准确性。

公开(公告)号：WO1988009920A1

公开(公告)日：1988-12-15

申请号：PCT/US1988001831

申请日：1988-06-02

Applicant: FUTREX, INC.

Inventor： FUTREX, INC. ,  ROSENTHAL, Robert, D.

IPC: G01J03/36

CPC classification number: A61B5/4872 ,  G01J2003/1213 ,  G01N21/255 ,  G01N21/3563 ,  G01N21/359 ,  G01N2201/0621

Abstract: An instrument (10) for near infrared interactance quantitative analysis measurements to improve accuracy and repeatability of the measured results. These objectives are achieved by placing a narrow bandpass optical filter (23) between near infrared emitting diode radiation sources (16, 16', 17, 17', 18 and 18') and a radiation transmission tube (12). The filter (23) allows for more distinct isolation of the desired wavelengths in the measurement to achieve improved accuracy and repeatability. The filters (23) also eliminate the time consuming task of sorting through several diodes in search of a particular diode (16, 16', 17, 17', 18 and 18') whose output wavelength band is centered at the desired wavelength.

Abstract translation: 用于近红外相互作用定量分析测量的仪器（10），以提高测量结果的准确性和可重复性。 这些目标通过将窄带通滤光器（23）放置在近红外发射二极管辐射源（16,16'，17,17'，18和18'）和辐射传输管（12）之间来实现。 过滤器（23）允许在测量中更理想地隔离所需的波长，以实现提高的精度和重复性。 滤波器（23）还消除了通过几个二极管分类以寻找其输​​出波段以期望波长为中心的特定二极管（16,16'，17,17'，18和18'）的耗时任务。

公开(公告)号：WO0042905A3

公开(公告)日：2000-11-30

申请号：PCT/US0001114

申请日：2000-01-19

Applicant: FUTREX INC

Inventor： HONIGS DAVID E ,  ROSENTHAL ROBERT D

IPC: A61B5/00 ,  G01N21/35

CPC classification number: A61B5/1455 ,  A61B5/14532

Abstract: A method and apparatus for performing quantitative noninvasive measurement of blood analytes, includes correction for measurement interference caused by pulse beat and changing body chemistry associated with blood circulation through the part of the body being measured as a function of time. A hypoglycemia monitor and alarm is provided which takes advantage of the methods described for separating pulse beat information from the measurement signals.

Abstract translation: 一种用于执行血液分析物的定量无创测量的方法和设备，包括对由脉搏跳动引起的测量干扰进行校正，并且改变与通过作为时间的函数测量的身体部位的血液循环相关的身体化学物质。 提供低血糖监测和警报，其利用所描述的用于从测量信号中分离脉搏差拍信息的方法。

公开(公告)号：WO1995031133A1

公开(公告)日：1995-11-23

申请号：PCT/US1995005987

申请日：1995-05-15

Applicant: FUTREX, INC.

Inventor： FUTREX, INC. ,  QUINTANA, Reynaldo

IPC: A61B05/00

CPC classification number: A61B5/1455 ,  A61B5/02422 ,  A61B5/02433 ,  A61B5/14532 ,  A61B5/14552 ,  G01N21/359

Abstract: An improved near-infrared quantitative analysis instrument (1) includes a number of removable finger inserts (30) each dimensioned for a different finger size, which facilitates properly aligning and fitting an individual user's finger into the optical system of the analysis instrument (1) taking into account the size of the individual's finger. The inserts (30) according to the present invention can be also designed to accommodate samples of various substances for quantitative analyte measurement.

Abstract translation: 改进的近红外定量分析仪器（1）包括多个可移动的手指插入物（30），每个可移动的手指插入件（30）的尺寸适合于不同的手指尺寸，这有助于将单个使用者的手指适当地对准和装配到分析仪器（1）的光学系统中， 考虑到个人手指的大小。 根据本发明的插入物（30）还可以被设计成适应用于定量分析物测量的各种物质的样品。

公开(公告)号：WO1990005955A1

公开(公告)日：1990-05-31

申请号：PCT/US1989005239

申请日：1989-11-16

Applicant: FUTREX, INC.

Inventor： FUTREX, INC. ,  ROSENTHAL, Robert, D.

IPC: G06F15/46

CPC classification number: G01N21/359

Abstract: In a near infrared quantitative analysis instrument an initial sample (10) is measured (18, 24) for a plurality of characteristics which include the ambient temperature of the analysis instrument at the time of the reading, the temperature of the sample itself, the optical energy level of the sample, the moisture content of the sample, and the percent protein of the sample. These characteristics are stored in a computer (14, 22) to provide a series of comparison criteria. A subsequent sample (10) is then measured (18, 24) for the same characteristics as the initial sample. The initial and subsequent characteristics are compared (26). The subsequent sample is determined to be substantially identical to the initial sample for a given criterion if the subsequent sample's measurement for the corresponding characteristic is within a tolerance for that criterion. If the subsequent sample is judged to be substantially identical to the initial sample for all criteria, it is determined to be substantially identical to the initial sample.

Abstract translation: 在近红外定量分析仪器中，对于多个特征测量（18,24）的初始样品（10），其包括在读取时分析仪器的环境温度，样品本身的温度，光学 样品的能级，样品的水分含量和样品的蛋白质百分比。 这些特征被存储在计算机（14,22）中以提供一系列比较标准。 然后对于与初始样品相同的特性，测量随后的样品（10）（18,24）。 比较初始和后续特征（26）。 如果后续样品对于相应特征的测量值在该标准的公差内，则后续样品被确定为与给定标准的初始样品基本相同。 如果后续样品被判断为与所有标准的初始样品基本相同，则确定其与初始样品基本相同。

公开(公告)号：WO1989008428A1

公开(公告)日：1989-09-21

申请号：PCT/US1989000997

申请日：1989-03-13

Applicant: FUTREX INC.

Inventor： FUTREX INC. ,  ROSENTHAL, Robert, D.

IPC: A61B06/00

CPC classification number: A61B5/4872 ,  A61B5/0059 ,  A61B5/441 ,  A61B2560/0233

Abstract: Method and apparatus for determining percent fat in a body wherein near-infrared radiation (16, 16') is transmitted into the body to achieve optical interactance between the body and the near-infrared radiation. Optical absorption by the body at one or more wavelengths of the near-infrared radiation is measured (28, 29). The measured absorption of near-infrared radiation is utilized to quantitatively determine the fat content of the body. Data on a plurality of physical parameters of the body, such as height, weight, exercise level, sex, race, waste-to-hip measurement and arm circumference, can be utilized along with the measured near-infrared absorption in the quantitative determination of body fat content.

Abstract translation: 用于确定身体中脂肪百分比的方法和装置，其中将近红外辐射（16,16'）传输到身体中以实现身体和近红外辐射之间的光学相互作用。 测量在近红外辐射的一个或多个波长处的身体的光学吸收（28,29）。 利用测量的近红外辐射吸收来定量测定身体的脂肪含量。 关于身体的多个物理参数的数据，例如高度，体重，运动水平，性别，种族，废物到臀部测量和手臂周长，可以与测量的近红外吸收一起用于定量测定 身体脂肪含量。

公开(公告)号：WO1995020906A1

公开(公告)日：1995-08-10

申请号：PCT/US1995000384

申请日：1995-01-12

Applicant: FUTREX, INC.

Inventor： FUTREX, INC. ,  ROSENTHAL, Robert, D.

IPC: A61B05/00

CPC classification number: A61B5/1455 ,  A61B5/14532

Abstract: A procedure for verifying the accuracy of a non-invasive blood glucose measurement instrument (10) utilizes in vitro or invasive measurement instruments (100), the accuracy of which is independently verifiable. Several glucose readings are taken with each instrument at approximately the same times. The measurement data from the in vitro instrument (100) is transferred to the non-invasive instrument (10) where it is compared to the data regarding the non-invasive measurements. If the difference between the measurements of the respective instruments is within a preset range, the non-invasive instrument is permitted to be used for an additional period of time. However, if the difference is beyond an acceptable limit, then the non-invasive instrument is prevented from taking any additional measurements and must be serviced or repaired.

Abstract translation: 用于验证非侵入性血糖测量仪器（10）的准确性的程序利用体外或侵入性测量仪器（100），其精度可独立验证。 在几乎相同的时间，每台仪器都会获取几个葡萄糖读数。 来自体外仪器（100）的测量数据被转移到非侵入性仪器（10），在那里将其与关于非侵入性测量的数据进行比较。 如果各个仪器的测量值之间的差异在预设范围内，则允许非侵入性仪器在另外一段时间内使用。 然而，如果差异超出了可接受的限度，那么防止非侵入性仪器进行任何额外的测量，并且必须进行维修或维修。

公开(公告)号：WO1995004924A1

公开(公告)日：1995-02-16

申请号：PCT/US1994009097

申请日：1994-08-09

Applicant: FUTREX, INC.

Inventor： FUTREX, INC. ,  ROSENTHAL, Robert, D. ,  PAYNTER, Lynn, N. ,  QUINTANA, Reynaldo, J.

IPC: G01N21/35

CPC classification number: A61B5/1455 ,  A61B5/02422 ,  A61B5/02433 ,  A61B5/14532 ,  A61B5/14552 ,  A61B2560/0252 ,  G01N21/359

Abstract: A near-infrared quantitative analysis instrument for measuring blood anlytes in a finger of a subject includes a temperature-sensing thermistor-type ring instrument (42) via a cable (41). A light shield glove (51) may be provided with the thermistor-type ring attached thereto.

Abstract translation: 用于测量受试者手指中的血液聚集体的近红外定量分析仪器包括经由电缆（41）的温度感测热敏电阻型环形器械（42）。 遮光手套（51）可以设置有附接到其上的热敏电阻型环。