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公开(公告)号：WO2013042095A1
公开(公告)日：2013-03-28
申请号：PCT/IB2012/055062
申请日：2012-09-24
Applicant: UNIVERSITÀ DEGLI STUDI DI ROMA "LA SAPIENZA" , FUTURA STEM CELLS SA , FRATI, Luigi , FRATI, Giacomo , NUTI, Marianna , PIERELLI, Luca
Inventor： FRATI, Luigi , FRATI, Giacomo , NUTI, Marianna , PIERELLI, Luca
CPC classification number: A01N1/0215 , A01N1/0278 , A01N1/0294
Abstract: The present invention relates to a rapid, simple, effective and economical method for preparing platelet lysate free of contaminants that can generate the transmission of diseases caused by viral, microbial, fungal or parasitic agents, also called inactivated lysate. The present invention relates to the use of the platelet lysate obtained as a coadjuvant for the culture, growth and/or expansion of stem cells, in particular mesenchymal, of mesenchymal stem cells derived from adipose tissue, fibroblasts and dendritic cells.
Abstract translation: 本发明涉及一种快速，简单，有效和经济的方法，用于制备不含污染物的血小板裂解物，其可产生由病毒，微生物，真菌或寄生虫（也称为灭活裂解物）引起的疾病的传播。 本发明涉及获得作为辅助剂的血小板裂解物在源自脂肪组织，成纤维细胞和树突状细胞的间充质干细胞的干细胞，特别是间充质的培养，生长和/或扩增中的用途。
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公开(公告)号：EP2757879B1
公开(公告)日：2018-08-29
申请号：EP12780851.7
申请日：2012-09-24
Inventor： FRATI, Giacomo , FRATI, Luigi , PIERELLI, Luca , NUTI, Marianna
CPC classification number: A01N1/0215 , A01N1/0278 , A01N1/0294
Abstract: The present invention relates to a rapid, simple, effective and economical method for preparing platelet lysate free of contaminants that can generate the transmission of diseases caused by viral, microbial, fungal or parasitic agents, also called inactivated lysate. The present invention relates to the use of the platelet lysate obtained as a coadjuvant for the culture, growth and/or expansion of stem cells, in particular mesenchymal, of mesenchymal stem cells derived from adipose tissue, fibroblasts and dendritic cells.
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公开(公告)号：EP2757879A1
公开(公告)日：2014-07-30
申请号：EP12780851.7
申请日：2012-09-24
Inventor： FRATI, Giacomo , FRATI, Luigi , PIERELLI, Luca , NUTI, Marianna
CPC classification number: A01N1/0215 , A01N1/0278 , A01N1/0294
Abstract: The present invention relates to a rapid, simple, effective and economical method for preparing platelet lysate free of contaminants that can generate the transmission of diseases caused by viral, microbial, fungal or parasitic agents, also called inactivated lysate. The present invention relates to the use of the platelet lysate obtained as a coadjuvant for the culture, growth and/or expansion of stem cells, in particular mesenchymal, of mesenchymal stem cells derived from adipose tissue, fibroblasts and dendritic cells.
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公开(公告)号：ITRM20110500A1
公开(公告)日：2013-03-24
申请号：ITRM20110500
申请日：2011-09-23
Applicant: FUTURA STEM CELLS SA , UNIV ROMA
Inventor： FRATI LUIGI , NUTI MARIANNA , PIERELLI LUCA
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