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1.发明公开NEW METHOD FOR THE MANUFACTURE OF THERAPEUTIC COMPOUNDS AND COMPOSITIONS, COMPOUNDS AND COMPOSITIONS PRODUCED THEREWHITH, AND THEIR USE 有权新方法用于生产治疗化合物和组合物对于这样制作的化合物和组合物及其用途
公开(公告)号：EP2004576A1
公开(公告)日：2008-12-24
申请号：EP07716121.4
申请日：2007-03-14
Applicant: Gustafsson, Lars E. , Linnarsso, Dag , Nilson, Kristofer
Inventor： Gustafsson, Lars E. , Linnarsso, Dag , Nilson, Kristofer
IPC: C07B43/02 , A61K31/70 , A61K31/7016 , A61P11/06 , A61P17/02 , A61P9/10 , A61P9/12 , C07C201/04 , C07H3/02 , C07H3/04
CPC classification number: C07C201/04 , C07B43/02 , C07C203/00
Abstract: Organic nitrites can be produced from a compound which is a mono/polyhydric alcohol or an aldehyde- or ketone-derivate thereof after de-aeration of the same, using NO gas, and stored in an environment saturated with gaseous NO. Organic nitrites produced according to the invention exhibit less impurities and improved storage stability compared to conventionally produced nitrites. The organic nitrites of the invention can easily be formulated into pharmaceutical compositions and have utility for the treatment of various conditions.
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2.发明授权NEW METHOD FOR THE MANUFACTURE OF THERAPEUTIC COMPOUNDS AND COMPOSITIONS, COMPOUNDS AND COMPOSITIONS PRODUCED THEREWHITH, AND THEIR USE 有权新方法用于生产治疗化合物和组合物对于这样制作的化合物和组合物及其用途
公开(公告)号：EP2004576B1
公开(公告)日：2011-11-23
申请号：EP07716121.4
申请日：2007-03-14
Applicant: GUSTAFSSON, Lars E. , LINNARSSON, Dag , NILSSON, Kristofer
Inventor： GUSTAFSSON, Lars E. , LINNARSSON, Dag , NILSSON, Kristofer
IPC: C07B43/02 , A61K31/70 , A61K31/7016 , A61P11/06 , A61P17/02 , A61P9/10 , A61P9/12 , C07C201/04 , C07H3/02 , C07H3/04
CPC classification number: C07C201/04 , C07B43/02 , C07C203/00
Abstract: Organic nitrites can be produced from a compound which is a mono/polyhydric alcohol or an aldehyde- or ketone-derivate thereof after de-aeration of the same, using NO gas, and stored in an environment saturated with gaseous NO. Organic nitrites produced according to the invention exhibit less impurities and improved storage stability compared to conventionally produced nitrites. The organic nitrites of the invention can easily be formulated into pharmaceutical compositions and have utility for the treatment of various conditions.
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Patent Agency Ranking3.发明公开NEW METHOD FOR THE MANUFACTURE OF THERAPEUTIC COMPOUNDS AND COMPOSITIONS, COMPOUNDS AND COMPOSITIONS PRODUCED THEREWHITH, AND THEIR USE 有权新方法用于生产治疗化合物和组合物对于这样制作的化合物和组合物及其用途
公开(公告)号：EP2004576A4
公开(公告)日：2009-12-02
申请号：EP07716121
申请日：2007-03-14
Applicant: GUSTAFSSON LARS E , LINNARSSO DAG , NILSON KRISTOFER
Inventor： GUSTAFSSON LARS E , LINNARSSO DAG , NILSON KRISTOFER
IPC: C07B43/02 , A61K31/70 , A61K31/7016 , A61P9/10 , A61P9/12 , A61P11/06 , A61P17/02 , C07C201/04 , C07H3/02 , C07H3/04
CPC classification number: C07C201/04 , C07B43/02 , C07C203/00
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公开(公告)号：AU2007225489A1
公开(公告)日：2007-09-20
申请号：AU2007225489
申请日：2007-03-14
Applicant: GUSTAFSSON LARS E , LINNARSSON DAG , NILSSON KRISTOFER
Inventor： LINNARSSON DAG , NILSSON KRISTOFER , GUSTAFSSON LARS E
IPC: C07B43/02 , A61K31/70 , A61K31/7016 , A61P9/10 , A61P9/12 , A61P11/06 , A61P17/02 , C07C201/04 , C07H3/02 , C07H3/04
Abstract: Organic nitrites can be produced from a compound which is a mono/polyhydric alcohol or an aldehyde- or ketone-derivate thereof after de-aeration of the same, using NO gas, and stored in an environment saturated with gaseous NO. Organic nitrites produced according to the invention exhibit less impurities and improved storage stability compared to conventionally produced nitrites. The organic nitrites of the invention can easily be formulated into pharmaceutical compositions and have utility for the treatment of various conditions.
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公开(公告)号：DK2004576T3
公开(公告)日：2012-03-05
申请号：DK07716121
申请日：2007-03-14
Applicant: GUSTAFSSON LARS E , LINNARSSON DAG , NILSSON KRISTOFER
Inventor： GUSTAFSSON LARS E , LINNARSSON DAG , NILSSON KRISTOFER
IPC: C07B43/02 , A61K31/70 , A61K31/7016 , A61P9/10 , A61P9/12 , A61P11/06 , A61P17/02 , C07C201/04 , C07H3/02 , C07H3/04
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公开(公告)号：AT534618T
公开(公告)日：2011-12-15
申请号：AT07716121
申请日：2007-03-14
Applicant: GUSTAFSSON LARS E , LINNARSSON DAG , NILSSON KRISTOFER
Inventor： GUSTAFSSON LARS E , LINNARSSON DAG , NILSSON KRISTOFER
IPC: C07B43/02 , A61K31/70 , A61K31/7016 , A61P9/10 , A61P9/12 , A61P11/06 , A61P17/02 , C07C201/04
Abstract: Organic nitrites can be produced from a compound which is a mono/polyhydric alcohol or an aldehyde- or ketone-derivate thereof after de-aeration of the same, using NO gas, and stored in an environment saturated with gaseous NO. Organic nitrites produced according to the invention exhibit less impurities and improved storage stability compared to conventionally produced nitrites. The organic nitrites of the invention can easily be formulated into pharmaceutical compositions and have utility for the treatment of various conditions.
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7.发明申请NEW METHOD FOR THE MANUFACTURE OF THERAPEUTIC COMPOUNDS AND COMPOSITIONS, COMPOUNDS AND COMPOSITIONS PRODUCED THEREWHITH, AND THEIR USE 审中-公开制备治疗化合物及其组合物的新方法，其生产的化合物和组合物及其使用
公开(公告)号：WO2007106034A1
公开(公告)日：2007-09-20
申请号：PCT/SE2007/050152
申请日：2007-03-14
Applicant: GUSTAFSSON, Lars, E , LINNARSSON, Dag , NILSSON, Kristofer
Inventor： GUSTAFSSON, Lars, E , LINNARSSON, Dag , NILSSON, Kristofer
IPC: C07B43/02 , A61K31/70 , A61K31/7016 , A61P11/06 , A61P17/02 , A61P9/10 , A61P9/12 , C07C201/04 , C07H3/02 , C07H3/04
CPC classification number: C07C201/04 , C07B43/02 , C07C203/00
Abstract: Organic nitrites can be produced from a compound which is a mono/polyhydric alcohol or an aldehyde- or ketone-derivate thereof after de-aeration of the same, using NO gas, and stored in an environment saturated with gaseous NO. Organic nitrites produced according to the invention exhibit less impurities and improved storage stability compared to conventionally produced nitrites. The organic nitrites of the invention can easily be formulated into pharmaceutical compositions and have utility for the treatment of various conditions.
Abstract translation: 有机亚硝酸盐可以通过使用NO气体在其通气之后从作为单/多元醇或其醛衍生物或酮衍生物的化合物生产，并储存在饱和有NO的环境中。 根据本发明生产的有机亚硝酸盐与常规生产的亚硝酸盐相比表现出较少的杂质和改善的储存稳定性。 本发明的有机亚硝酸盐可以容易地配制成药物组合物，并具有治疗各种病症的效用。
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